From HPO
Short thumb- MedGen UID:
- 98469
- •Concept ID:
- C0431890
- •
- Congenital Abnormality
Hypoplasia (congenital reduction in size) of the thumb.
Short distal phalanx of finger- MedGen UID:
- 326590
- •Concept ID:
- C1839829
- •
- Finding
Short distance from the end of the finger to the most distal interphalangeal crease or the distal interphalangeal joint flexion point. That is, hypoplasia of one or more of the distal phalanx of finger.
Short hallux- MedGen UID:
- 400890
- •Concept ID:
- C1865992
- •
- Finding
Underdevelopment (hypoplasia) of the big toe.
Shortening of all distal phalanges of the fingers- MedGen UID:
- 867248
- •Concept ID:
- C4021608
- •
- Finding
Hypoplasia of all of the distal phalanx of finger.
Ventricular septal defect- MedGen UID:
- 42366
- •Concept ID:
- C0018818
- •
- Congenital Abnormality
A hole between the two bottom chambers (ventricles) of the heart. The defect is centered around the most superior aspect of the ventricular septum.
Hypertensive disorder- MedGen UID:
- 6969
- •Concept ID:
- C0020538
- •
- Disease or Syndrome
The presence of chronic increased pressure in the systemic arterial system.
Pulmonary artery hypoplasia- MedGen UID:
- 75585
- •Concept ID:
- C0265910
- •
- Congenital Abnormality
Underdevelopment of the pulmonary artery.
Peripheral pulmonary artery stenosis- MedGen UID:
- 138014
- •Concept ID:
- C0345030
- •
- Finding
Stenosis of a peripheral branch of the pulmonary artery.
Pulmonic stenosis- MedGen UID:
- 408291
- •Concept ID:
- C1956257
- •
- Disease or Syndrome
A narrowing of the right ventricular outflow tract that can occur at the pulmonary valve (valvular stenosis), below the pulmonary valve (infundibular stenosis), or above the pulmonary valve (supravalvar stenosis).
Growth abnormality- MedGen UID:
- 808205
- •Concept ID:
- C0262361
- •
- Finding
Macrotia- MedGen UID:
- 488785
- •Concept ID:
- C0152421
- •
- Congenital Abnormality
Median longitudinal ear length greater than two standard deviations above the mean and median ear width greater than two standard deviations above the mean (objective); or, apparent increase in length and width of the pinna (subjective).
Hearing impairment- MedGen UID:
- 235586
- •Concept ID:
- C1384666
- •
- Disease or Syndrome
A decreased magnitude of the sensory perception of sound.
Intellectual disability, mild- MedGen UID:
- 10044
- •Concept ID:
- C0026106
- •
- Mental or Behavioral Dysfunction
Mild intellectual disability is defined as an intelligence quotient (IQ) in the range of 50-69.
Seizure- MedGen UID:
- 20693
- •Concept ID:
- C0036572
- •
- Sign or Symptom
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain.
Global developmental delay- MedGen UID:
- 107838
- •Concept ID:
- C0557874
- •
- Finding
A delay in the achievement of motor or mental milestones in the domains of development of a child, including motor skills, speech and language, cognitive skills, and social and emotional skills. This term should only be used to describe children younger than five years of age.
Tracheal calcification- MedGen UID:
- 75539
- •Concept ID:
- C0264324
- •
- Disease or Syndrome
Calcification (abnormal deposits of calcium) in the tracheal tissues.
Cerebral calcification- MedGen UID:
- 124360
- •Concept ID:
- C0270685
- •
- Finding
The presence of calcium deposition within the cerebrum.
Calcification of the auricular cartilage- MedGen UID:
- 278057
- •Concept ID:
- C1408806
- •
- Pathologic Function
Ossification affecting the external ear cartilage.
Costal cartilage calcification- MedGen UID:
- 344533
- •Concept ID:
- C1855608
- •
- Finding
Calcification of the costal cartilages, which are bars of hyaline cartilage found at the anterior ends of the ribs which serve to prolong the ribs forward and contribute to the elasticity of the walls of the thorax.
Premature fusion of phalangeal epiphyses- MedGen UID:
- 344537
- •Concept ID:
- C1855620
- •
- Finding
Fusion of the epiphysis and metaphysis of one or more phalanges prior to the normal age or stage of growth.
Malar flattening- MedGen UID:
- 347616
- •Concept ID:
- C1858085
- •
- Finding
Underdevelopment of the malar prominence of the jugal bone (zygomatic bone in mammals), appreciated in profile, frontal view, and/or by palpation.
Epiphyseal stippling- MedGen UID:
- 349104
- •Concept ID:
- C1859126
- •
- Finding
The presence of abnormal punctate (speckled, dot-like) calcifications in one or more epiphyses.
Airway obstruction- MedGen UID:
- 1387
- •Concept ID:
- C0001883
- •
- Disease or Syndrome
Obstruction of conducting airways of the lung.
Emphysema- MedGen UID:
- 18764
- •Concept ID:
- C0034067
- •
- Disease or Syndrome
A subcategory of chronic obstructive pulmonary disease (COPD). It occurs in people who smoke and suffer from chronic bronchitis. It is characterized by inflation of the alveoli, alveolar wall damage, and reduction in the number of alveoli, resulting in difficulty breathing.
Recurrent bronchitis- MedGen UID:
- 148159
- •Concept ID:
- C0741796
- •
- Disease or Syndrome
An increased susceptibility to bronchitis as manifested by a history of recurrent bronchitis.
Cartilaginous ossification of larynx- MedGen UID:
- 344538
- •Concept ID:
- C1855622
- •
- Finding
Ossification affecting the set of cartilages of larynx.
Sinusitis- MedGen UID:
- 20772
- •Concept ID:
- C0037199
- •
- Disease or Syndrome
Inflammation of the paranasal sinuses owing to a viral, bacterial, or fungal infection, allergy, or an autoimmune reaction.
Chronic sinusitis- MedGen UID:
- 101751
- •Concept ID:
- C0149516
- •
- Disease or Syndrome
A chronic form of sinusitis.
Recurrent otitis media- MedGen UID:
- 155436
- •Concept ID:
- C0747085
- •
- Disease or Syndrome
Increased susceptibility to otitis media, as manifested by recurrent episodes of otitis media.
Hypernasal speech- MedGen UID:
- 107884
- •Concept ID:
- C0566620
- •
- Finding
A type of speech characterized by the presence of an abnormally increased nasal airflow during speech associated with structural abnormality of the nasal passages.
Long face- MedGen UID:
- 324419
- •Concept ID:
- C1836047
- •
- Finding
Facial height (length) is more than 2 standard deviations above the mean (objective); or, an apparent increase in the height (length) of the face (subjective).
Depressed nasal bridge- MedGen UID:
- 373112
- •Concept ID:
- C1836542
- •
- Finding
Posterior positioning of the nasal root in relation to the overall facial profile for age.
Deep philtrum- MedGen UID:
- 374311
- •Concept ID:
- C1839797
- •
- Finding
Accentuated, prominent philtral ridges giving rise to an exaggerated groove in the midline between the nasal base and upper vermillion border.
Wide nasal bridge- MedGen UID:
- 341441
- •Concept ID:
- C1849367
- •
- Finding
Increased breadth of the nasal bridge (and with it, the nasal root).
Midface retrusion- MedGen UID:
- 339938
- •Concept ID:
- C1853242
- •
- Anatomical Abnormality
Posterior positions and/or vertical shortening of the infraorbital and perialar regions, or increased concavity of the face and/or reduced nasolabial angle.
Cartilaginous ossification of nose- MedGen UID:
- 340915
- •Concept ID:
- C1855616
- •
- Finding
- Abnormality of head or neck
- Abnormality of limbs
- Abnormality of the cardiovascular system
- Abnormality of the immune system
- Abnormality of the musculoskeletal system
- Abnormality of the nervous system
- Abnormality of the respiratory system
- Abnormality of the voice
- Ear malformation
- Growth abnormality