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microgyria

MedGen UID:
386642
Concept ID:
C2362742
Congenital Abnormality
Synonym: Microgyria
SNOMED CT: Microgyria (4945003)

Definition

A congenital abnormality characterized by the presence of abnormally small convolutions in the brain. It results in mental retardation. [from NCI]

Term Hierarchy

Recent clinical studies

Etiology

Hill C, Noureldein M, Karkhanis P, Kinning E, Vijay S, Gowda H
Am J Med Genet A 2023 Mar;191(3):859-863. Epub 2022 Dec 20 doi: 10.1002/ajmg.a.63083. PMID: 36538928
Kopyta I, Jamroz E, Kluczewska E, Sarecka-Hujar B
J Child Neurol 2014 Apr;29(4):442-9. Epub 2013 Mar 14 doi: 10.1177/0883073813478660. PMID: 23503883
Threlkeld SW, McClure MM, Bai J, Wang Y, LoTurco JJ, Rosen GD, Fitch RH
Brain Res Bull 2007 Mar 15;71(5):508-14. Epub 2006 Dec 5 doi: 10.1016/j.brainresbull.2006.11.005. PMID: 17259020Free PMC Article
Barkovich AJ, Peck WW
AJNR Am J Neuroradiol 1997 Jun-Jul;18(6):1163-70. PMID: 9194444Free PMC Article
Guerrini R, Dravet C, Raybaud C, Roger J, Bureau M, Battaglia A, Livet MO, Gambarelli D, Robain O
Dev Med Child Neurol 1992 Aug;34(8):706-18. doi: 10.1111/j.1469-8749.1992.tb11506.x. PMID: 1644233

Diagnosis

Hill C, Noureldein M, Karkhanis P, Kinning E, Vijay S, Gowda H
Am J Med Genet A 2023 Mar;191(3):859-863. Epub 2022 Dec 20 doi: 10.1002/ajmg.a.63083. PMID: 36538928
Chandra SP, Kurwale NS, Chibber SS, Banerji J, Dwivedi R, Garg A, Bal C, Tripathi M, Sarkar C, Tripathi M
Neurosurgery 2016 May;78(5):743-51. doi: 10.1227/NEU.0000000000001060. PMID: 26474092
Kopyta I, Jamroz E, Kluczewska E, Sarecka-Hujar B
J Child Neurol 2014 Apr;29(4):442-9. Epub 2013 Mar 14 doi: 10.1177/0883073813478660. PMID: 23503883
Hablitz JJ, DeFazio T
Epilepsy Res 1998 Sep;32(1-2):75-82. doi: 10.1016/s0920-1211(98)00041-2. PMID: 9761310
Barkovich AJ, Peck WW
AJNR Am J Neuroradiol 1997 Jun-Jul;18(6):1163-70. PMID: 9194444Free PMC Article

Therapy

Stöllberger C, Finsterer J
Neurol Neurochir Pol 2017 Mar-Apr;51(2):194-196. Epub 2017 Feb 3 doi: 10.1016/j.pjnns.2017.01.010. PMID: 28215696
Threlkeld SW, Hill CA, Rosen GD, Fitch RH
Int J Dev Neurosci 2009 Jun;27(4):321-8. Epub 2009 Apr 1 doi: 10.1016/j.ijdevneu.2009.03.007. PMID: 19460626Free PMC Article
Cui C, Sakata-Haga H, Ohta K, Nishida M, Yashiki M, Sawada K, Fukui Y
Congenit Anom (Kyoto) 2006 Dec;46(4):180-7. doi: 10.1111/j.1741-4520.2006.00126.x. PMID: 17096818

Prognosis

Kopyta I, Jamroz E, Kluczewska E, Sarecka-Hujar B
J Child Neurol 2014 Apr;29(4):442-9. Epub 2013 Mar 14 doi: 10.1177/0883073813478660. PMID: 23503883
Gérard-Blanluet M, Sheen V, Machinis K, Neal J, Apse K, Danan C, Sinico M, Brugières P, Mage K, Ratsimbazafy L, Elbez A, Janaud JC, Amselem S, Walsh C, Encha-Razavi F
Am J Med Genet A 2006 May 15;140(10):1041-6. doi: 10.1002/ajmg.a.31197. PMID: 16596669
Güngör N, Coşkun T, Akçören Z, Cağlar M
Turk J Pediatr 1994 Apr-Jun;36(2):145-52. PMID: 8016916

Clinical prediction guides

Kopyta I, Jamroz E, Kluczewska E, Sarecka-Hujar B
J Child Neurol 2014 Apr;29(4):442-9. Epub 2013 Mar 14 doi: 10.1177/0883073813478660. PMID: 23503883
Rial D, Xikota JC, Miozzo A, Cruz VE, Prediger RD, Walz R
Brain Res Bull 2009 May 29;79(3-4):177-81. Epub 2009 Feb 21 doi: 10.1016/j.brainresbull.2009.02.003. PMID: 19429188
Jacobs KM, Kharazia VN, Prince DA
Epilepsy Res 1999 Sep;36(2-3):165-88. doi: 10.1016/s0920-1211(99)00050-9. PMID: 10515164
Hablitz JJ, DeFazio T
Epilepsy Res 1998 Sep;32(1-2):75-82. doi: 10.1016/s0920-1211(98)00041-2. PMID: 9761310
Urich H
Clin Exp Neurol 1979;16:119-31. PMID: 233076

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