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Disorder of ear

MedGen UID:
3946
•Concept ID:
C0013447
•
Disease or Syndrome
Synonym: Disease of ear
SNOMED CT: Disorder of ear (25906001)
 
Monarch Initiative: MONDO:0021205

Definition

A non-neoplastic or neoplastic disorder that affects the ear. Representative examples include infections, hearing disorders, benign neoplasms, and carcinomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDisorder of ear

Professional guidelines

PubMed

Therapeutic strategies in the treatment of Menière's disease: the Italian experience.
Quaranta N, Picciotti P, Porro G, Sterlicchio B, Danesi G, Petrone P, Asprella Libonati G
Eur Arch Otorhinolaryngol 2019 Jul;276(7):1943-1950. Epub 2019 Apr 11 doi: 10.1007/s00405-019-05423-7. PMID: 30976990

Recent clinical studies

Etiology

Clinical Practice Guideline (Update): Earwax (Cerumen Impaction).
Schwartz SR, Magit AE, Rosenfeld RM, Ballachanda BB, Hackell JM, Krouse HJ, Lawlor CM, Lin K, Parham K, Stutz DR, Walsh S, Woodson EA, Yanagisawa K, Cunningham ER Jr
Otolaryngol Head Neck Surg 2017 Jan;156(1_suppl):S1-S29. doi: 10.1177/0194599816671491. PMID: 28045591
Ototoxicity and cancer therapy.
Landier W
Cancer 2016 Jun 1;122(11):1647-58. Epub 2016 Feb 9 doi: 10.1002/cncr.29779. PMID: 26859792
Surgical anatomy and pathology of the middle ear.
Luers JC, Hüttenbrink KB
J Anat 2016 Feb;228(2):338-53. Epub 2015 Oct 19 doi: 10.1111/joa.12389. PMID: 26482007Free PMC Article
Cerumen removal--current challenges.
Grossan M
Ear Nose Throat J 1998 Jul;77(7):541-6, 548. PMID: 9693470
Multifrequency tympanometry.
Colletti V
Audiology 1977 Jul-Aug;16(4):278-87. doi: 10.3109/00206097709071839. PMID: 883908

Diagnosis

Updates in Eustachian Tube Dysfunction.
Maddineni S, Ahmad I
Otolaryngol Clin North Am 2022 Dec;55(6):1151-1164. doi: 10.1016/j.otc.2022.07.010. PMID: 36371132
Unlearning the ABCs of Tympanometry.
McCoul ED
Otolaryngol Head Neck Surg 2021 Oct;165(4):491-492. Epub 2021 Mar 9 doi: 10.1177/0194599821995828. PMID: 33687296
Chronic Ear Disease.
Emmett SD, Kokesh J, Kaylie D
Med Clin North Am 2018 Nov;102(6):1063-1079. Epub 2018 Sep 20 doi: 10.1016/j.mcna.2018.06.008. PMID: 30342609
Clinical Practice Guideline (Update): Earwax (Cerumen Impaction).
Schwartz SR, Magit AE, Rosenfeld RM, Ballachanda BB, Hackell JM, Krouse HJ, Lawlor CM, Lin K, Parham K, Stutz DR, Walsh S, Woodson EA, Yanagisawa K, Cunningham ER Jr
Otolaryngol Head Neck Surg 2017 Jan;156(1_suppl):S1-S29. doi: 10.1177/0194599816671491. PMID: 28045591
Eustachian tube dysfunction: consensus statement on definition, types, clinical presentation and diagnosis.
Schilder AG, Bhutta MF, Butler CC, Holy C, Levine LH, Kvaerner KJ, Norman G, Pennings RJ, Poe D, Silvola JT, Sudhoff H, Lund VJ
Clin Otolaryngol 2015 Oct;40(5):407-11. doi: 10.1111/coa.12475. PMID: 26347263Free PMC Article

Therapy

Optical Identification of Middle Ear Infection.
Prasad A, Hasan SMA, Gartia MR
Molecules 2020 May 9;25(9) doi: 10.3390/molecules25092239. PMID: 32397569Free PMC Article
Advances in Understanding, Diagnosis, and Treatment of Tinnitus.
Tang D, Li H, Chen L
Adv Exp Med Biol 2019;1130:109-128. doi: 10.1007/978-981-13-6123-4_7. PMID: 30915704
Clinical Practice Guideline (Update): Earwax (Cerumen Impaction).
Schwartz SR, Magit AE, Rosenfeld RM, Ballachanda BB, Hackell JM, Krouse HJ, Lawlor CM, Lin K, Parham K, Stutz DR, Walsh S, Woodson EA, Yanagisawa K, Cunningham ER Jr
Otolaryngol Head Neck Surg 2017 Jan;156(1_suppl):S1-S29. doi: 10.1177/0194599816671491. PMID: 28045591
Ototoxicity and cancer therapy.
Landier W
Cancer 2016 Jun 1;122(11):1647-58. Epub 2016 Feb 9 doi: 10.1002/cncr.29779. PMID: 26859792
Cerumen removal--current challenges.
Grossan M
Ear Nose Throat J 1998 Jul;77(7):541-6, 548. PMID: 9693470

Prognosis

Dermatologic Conditions of the External Ear: Basics, Updates, and Pearls.
Leibowitz R, Koblinski JE, Hogue LM, Cheeley JT, Blalock TW
Otolaryngol Clin North Am 2023 Oct;56(5):949-963. Epub 2023 Jul 7 doi: 10.1016/j.otc.2023.05.014. PMID: 37423814
Management of retraction pockets: historic and novel approaches.
Spinos D, Mallick S, Judd O
J Laryngol Otol 2022 Jul;136(7):582-587. Epub 2022 Jan 7 doi: 10.1017/S0022215121004321. PMID: 34991748
Otologic manifestations of Susac syndrome.
Patel VA, Dunklebarger M, Zacharia TT, Isildak H
Acta Otorhinolaryngol Ital 2018 Dec;38(6):544-553. doi: 10.14639/0392-100X-2166. PMID: 30623900Free PMC Article
Hearing loss in autoimmune disorders: Prevalence and therapeutic options.
Mancini P, Atturo F, Di Mario A, Portanova G, Ralli M, De Virgilio A, de Vincentiis M, Greco A
Autoimmun Rev 2018 Jul;17(7):644-652. Epub 2018 May 3 doi: 10.1016/j.autrev.2018.01.014. PMID: 29729446
Primary ciliary dyskinesia in adults.
Honoré I, Burgel PR
Rev Mal Respir 2016 Feb;33(2):165-89. Epub 2015 Dec 1 doi: 10.1016/j.rmr.2015.10.743. PMID: 26654126

Clinical prediction guides

Dermatologic Conditions of the External Ear: Basics, Updates, and Pearls.
Leibowitz R, Koblinski JE, Hogue LM, Cheeley JT, Blalock TW
Otolaryngol Clin North Am 2023 Oct;56(5):949-963. Epub 2023 Jul 7 doi: 10.1016/j.otc.2023.05.014. PMID: 37423814
Middle-ear disease in children with cleft palate.
Karanth TK, Whittemore KR
Auris Nasus Larynx 2018 Dec;45(6):1143-1151. doi: 10.1016/j.anl.2018.04.012. PMID: 29764722
Ototoxicity and cancer therapy.
Landier W
Cancer 2016 Jun 1;122(11):1647-58. Epub 2016 Feb 9 doi: 10.1002/cncr.29779. PMID: 26859792
Understanding platinum-induced ototoxicity.
Langer T, am Zehnhoff-Dinnesen A, Radtke S, Meitert J, Zolk O
Trends Pharmacol Sci 2013 Aug;34(8):458-69. Epub 2013 Jun 13 doi: 10.1016/j.tips.2013.05.006. PMID: 23769626
Multifrequency tympanometry.
Colletti V
Audiology 1977 Jul-Aug;16(4):278-87. doi: 10.3109/00206097709071839. PMID: 883908

Recent systematic reviews

Systemic pharmacological interventions for Ménière's disease.
Webster KE, Galbraith K, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Cochrane Database Syst Rev 2023 Feb 23;2(2):CD015171. doi: 10.1002/14651858.CD015171.pub2. PMID: 36827524Free PMC Article
Hearing Loss, Tinnitus, and Dizziness in COVID-19: A Systematic Review and Meta-Analysis.
Jafari Z, Kolb BE, Mohajerani MH
Can J Neurol Sci 2022 Mar;49(2):184-195. Epub 2021 Apr 12 doi: 10.1017/cjn.2021.63. PMID: 33843530Free PMC Article
Management of paediatric acute mastoiditis: systematic review.
Loh R, Phua M, Shaw CL
J Laryngol Otol 2018 Feb;132(2):96-104. Epub 2017 Sep 7 doi: 10.1017/S0022215117001840. PMID: 28879826
Vestibular rehabilitation for unilateral peripheral vestibular dysfunction.
McDonnell MN, Hillier SL
Cochrane Database Syst Rev 2015 Jan 13;1:CD005397. doi: 10.1002/14651858.CD005397.pub4. PMID: 25581507
Burden of disease caused by otitis media: systematic review and global estimates.
Monasta L, Ronfani L, Marchetti F, Montico M, Vecchi Brumatti L, Bavcar A, Grasso D, Barbiero C, Tamburlini G
PLoS One 2012;7(4):e36226. Epub 2012 Apr 30 doi: 10.1371/journal.pone.0036226. PMID: 22558393Free PMC Article

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