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Ehrlich tumor carcinoma

MedGen UID:
40103
•Concept ID:
C0007125
•
Experimental Model of Disease; Neoplastic Process
Synonyms: Ascites Tumor, Ehrlich; Carcinoma, Ehrlich Tumor; Ehrlich Ascites Tumor; Ehrlich Tumor Carcinoma; Tumor, Ehrlich Ascites
 
Monarch Initiative: MONDO:0006739

Definition

A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEhrlich tumor carcinoma

Professional guidelines

PubMed

Design, Formulation and in vivo Evaluation of Novel Honokiol-Loaded PEGylated PLGA Nanocapsules for Treatment of Breast Cancer.
Haggag YA, Ibrahim RR, Hafiz AA
Int J Nanomedicine 2020;15:1625-1642. Epub 2020 Mar 9 doi: 10.2147/IJN.S241428. PMID: 32210557Free PMC Article
Enhanced anticancer activity of combined treatment of imatinib and dipyridamole in solid Ehrlich carcinoma-bearing mice.
El-Sisi AE, Sokar SS, Ibrahim HA, Abu-Risha SE
Naunyn Schmiedebergs Arch Pharmacol 2020 Jun;393(6):1113-1129. Epub 2020 Jan 16 doi: 10.1007/s00210-019-01803-2. PMID: 31950222
Solid Ehrlich tumor growth treatment by magnetic waves.
Ali FM, El Gebaly RH, El Hag MA, Rohaim AM
Technol Health Care 2011;19(6):455-67. doi: 10.3233/THC-2011-0649. PMID: 22129946

Recent clinical studies

Etiology

Immune Stimulating Outcome of Chrysin and γ-Irradiation via Apoptotic Activation Against Solid Ehrlich Carcinoma Bearing Mice.
El Bakary NM, Alsharkawy AZ, Shouaib ZA, Barakat EMS
Integr Cancer Ther 2022 Jan-Dec;21:15347354221096668. doi: 10.1177/15347354221096668. PMID: 35543434Free PMC Article
Anticancer Effects of New Ceramides Isolated from the Red Sea Red Algae Hypnea musciformis in a Model of Ehrlich Ascites Carcinoma: LC-HRMS Analysis Profile and Molecular Modeling.
Elhady SS, Habib ES, Abdelhameed RFA, Goda MS, Hazem RM, Mehanna ET, Helal MA, Hosny KM, Diri RM, Hassanean HA, Ibrahim AK, Eltamany EE, Abdelmohsen UR, Ahmed SA
Mar Drugs 2022 Jan 10;20(1) doi: 10.3390/md20010063. PMID: 35049918Free PMC Article
The effect of antioxidants in Ehrlich Ascites Cancer.
Yılmaz S, Tokpınar A, Eroğlu E, Ateş Ş, Zahid R, Avnioğlu S, Bozkurt Ö, Nisari M
Cell Mol Biol (Noisy-le-grand) 2021 Sep 29;67(2):20-24. doi: 10.14715/cmb/2021.67.2.4. PMID: 34817342
Enhanced anticancer activity of combined treatment of imatinib and dipyridamole in solid Ehrlich carcinoma-bearing mice.
El-Sisi AE, Sokar SS, Ibrahim HA, Abu-Risha SE
Naunyn Schmiedebergs Arch Pharmacol 2020 Jun;393(6):1113-1129. Epub 2020 Jan 16 doi: 10.1007/s00210-019-01803-2. PMID: 31950222
Toxicity and Antitumor Activity of a Thiophene-Acridine Hybrid.
Lisboa T, Silva D, Duarte S, Ferreira R, Andrade C, Lopes AL, Ribeiro J, Farias D, Moura R, Reis M, Medeiros K, Magalhães H, Sobral M
Molecules 2019 Dec 24;25(1) doi: 10.3390/molecules25010064. PMID: 31878135Free PMC Article

Diagnosis

Growth inhibition and pro-apoptotic activity of violacein in Ehrlich ascites tumor.
Bromberg N, Dreyfuss JL, Regatieri CV, Palladino MV, Durán N, Nader HB, Haun M, Justo GZ
Chem Biol Interact 2010 Jun 7;186(1):43-52. Epub 2010 Apr 21 doi: 10.1016/j.cbi.2010.04.016. PMID: 20416285
Photochemical and phototoxic activity of berberine on murine fibroblast NIH-3T3 and Ehrlich ascites carcinoma cells.
Jantová S, Letasiová S, Brezová V, Cipák L, Lábaj J
J Photochem Photobiol B 2006 Dec 1;85(3):163-76. Epub 2006 Aug 14 doi: 10.1016/j.jphotobiol.2006.07.001. PMID: 16905326
Regulation of tumour cell sensitivity to TNF-induced oxidative stress and cytotoxicity: role of glutathione.
Obrador E, Navarro J, Mompo J, Asensi M, Pellicer JA, Estrela JM
Biofactors 1998;8(1-2):23-6. doi: 10.1002/biof.5520080105. PMID: 9699004
Membrane lipid composition and cellular function.
Spector AA, Yorek MA
J Lipid Res 1985 Sep;26(9):1015-35. PMID: 3906008
Na+ + K+ + 2Cl- cotransport in animal cells--its role in volume regulation.
Geck P, Pfeiffer B
Ann N Y Acad Sci 1985;456:166-82. doi: 10.1111/j.1749-6632.1985.tb14862.x. PMID: 2418724

Therapy

The effect of antioxidants in Ehrlich Ascites Cancer.
Yılmaz S, Tokpınar A, Eroğlu E, Ateş Ş, Zahid R, Avnioğlu S, Bozkurt Ö, Nisari M
Cell Mol Biol (Noisy-le-grand) 2021 Sep 29;67(2):20-24. doi: 10.14715/cmb/2021.67.2.4. PMID: 34817342
What are the immune responses during the growth of Ehrlich's tumor in ascitic and solid form?
Feitosa IB, Mori B, Teles CBG, Costa AGD
Life Sci 2021 Jan 1;264:118578. Epub 2020 Oct 13 doi: 10.1016/j.lfs.2020.118578. PMID: 33058910
Enhanced anticancer activity of combined treatment of imatinib and dipyridamole in solid Ehrlich carcinoma-bearing mice.
El-Sisi AE, Sokar SS, Ibrahim HA, Abu-Risha SE
Naunyn Schmiedebergs Arch Pharmacol 2020 Jun;393(6):1113-1129. Epub 2020 Jan 16 doi: 10.1007/s00210-019-01803-2. PMID: 31950222
Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
Medhat AM, Azab KS, Said MM, El Fatih NM, El Bakary NM
Tumour Biol 2017 Oct;39(10):1010428317728480. doi: 10.1177/1010428317728480. PMID: 29022496
Anticancer activity of salicin and fenofibrate.
Sabaa M, ELFayoumi HM, Elshazly S, Youns M, Barakat W
Naunyn Schmiedebergs Arch Pharmacol 2017 Oct;390(10):1061-1071. Epub 2017 Jul 21 doi: 10.1007/s00210-017-1407-y. PMID: 28733879

Prognosis

Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line.
Agrawal SS, Saraswati S, Mathur R, Pandey M
Life Sci 2011 Aug 1;89(5-6):147-58. Epub 2011 Jun 13 doi: 10.1016/j.lfs.2011.05.020. PMID: 21684292
Antitumor and cytotoxic activities of methanol extract of Indigofera linnaei Ali.
Kumar RS, Rajkapoor B, Perumal P
Asian Pac J Cancer Prev 2011;12(3):613-8. PMID: 21627353
Antitumor and cytotoxic effects of Phyllanthus polyphyllus on Ehrlich ascites carcinoma and human cancer cell lines.
Rajkapoor B, Sankari M, Sumithra M, Anbu J, Harikrishnan N, Gobinath M, Suba V, Balaji R
Biosci Biotechnol Biochem 2007 Sep;71(9):2177-83. Epub 2007 Sep 7 doi: 10.1271/bbb.70149. PMID: 17827693
Induction of cytogenetic damage in human lymphocytes in vitro and of antineoplastic effects in Ehrlich ascites tumor cells in vivo treated by methotrexate, hyperthermia and/or caffeine.
Maskaleris T, Lialiaris T, Triantaphyllidis C
Mutat Res 1998 Dec 3;422(2):229-36. doi: 10.1016/s0027-5107(98)00198-5. PMID: 9838133
Membrane lipid composition and cellular function.
Spector AA, Yorek MA
J Lipid Res 1985 Sep;26(9):1015-35. PMID: 3906008

Clinical prediction guides

Anticancer Effects of New Ceramides Isolated from the Red Sea Red Algae Hypnea musciformis in a Model of Ehrlich Ascites Carcinoma: LC-HRMS Analysis Profile and Molecular Modeling.
Elhady SS, Habib ES, Abdelhameed RFA, Goda MS, Hazem RM, Mehanna ET, Helal MA, Hosny KM, Diri RM, Hassanean HA, Ibrahim AK, Eltamany EE, Abdelmohsen UR, Ahmed SA
Mar Drugs 2022 Jan 10;20(1) doi: 10.3390/md20010063. PMID: 35049918Free PMC Article
Anti-proliferative effects of the combination of Sulfamethoxazole and Quercetin via caspase3 and NFkB gene regulation: an in vitro and in vivo study.
Sahyon HAE, Ramadan ENM, Althobaiti F, Mashaly MMA
Naunyn Schmiedebergs Arch Pharmacol 2022 Feb;395(2):227-246. Epub 2022 Jan 7 doi: 10.1007/s00210-021-02174-3. PMID: 34994822
Acylated chitosan anchored paclitaxel loaded liposomes: Pharmacokinetic and biodistribution study in Ehrlich ascites tumor bearing mice.
Nanda B, Manjappa AS, Chuttani K, Balasinor NH, Mishra AK, Ramachandra Murthy RS
Int J Biol Macromol 2019 Feb 1;122:367-379. Epub 2018 Oct 17 doi: 10.1016/j.ijbiomac.2018.10.071. PMID: 30342146
Qa-2 expression levels is related with tumor-infiltrating lymphocytes profile during solid Ehrlich tumor development.
da Silva IL, Veloso ES, Gonçalves INN, Braga AD, Lopes MTP, Cassali GD, Quintanilla M, Simões RT, Ferreira E
Biomed Pharmacother 2017 Aug;92:750-756. Epub 2017 Jun 4 doi: 10.1016/j.biopha.2017.05.135. PMID: 28591688
Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line.
Agrawal SS, Saraswati S, Mathur R, Pandey M
Life Sci 2011 Aug 1;89(5-6):147-58. Epub 2011 Jun 13 doi: 10.1016/j.lfs.2011.05.020. PMID: 21684292

Recent systematic reviews

What are the immune responses during the growth of Ehrlich's tumor in ascitic and solid form?
Feitosa IB, Mori B, Teles CBG, Costa AGD
Life Sci 2021 Jan 1;264:118578. Epub 2020 Oct 13 doi: 10.1016/j.lfs.2020.118578. PMID: 33058910

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