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Metastatic neoplasm

MedGen UID:
422476
Concept ID:
C2939420
Neoplastic Process
Synonyms: metastatic disease; Metastatic Neoplasm; metastatic neoplasm; Metastatic Tumor; metastatic tumor; metastatic tumour; Neoplasm, metastatic; Neoplasm, secondary; Tumor, metastatic; Tumor, secondary
SNOMED CT: Neoplasm, metastatic (14799000); Tumor, metastatic (14799000); Neoplasm, secondary (14799000); Tumor, secondary (14799000)
 
Monarch Initiative: MONDO:0024883

Definition

A tumor that has spread from its original (primary) site of growth to another site, close to or distant from the primary site. Metastasis is characteristic of advanced malignancies, but in rare instances can be seen in neoplasms lacking malignant morphology. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic neoplasm

Professional guidelines

PubMed

Bekaert L, Emery E, Levallet G, Lechapt-Zalcman E
Brain Tumor Pathol 2017 Jan;34(1):8-19. Epub 2016 Nov 22 doi: 10.1007/s10014-016-0275-3. PMID: 27878432
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Recent clinical studies

Etiology

Plaza JA, Chung C, Wick M, Sangueza M, Gru A
Am J Dermatopathol 2022 Mar 1;44(3):155-162. doi: 10.1097/DAD.0000000000001844. PMID: 35171883
Cato LD, Evans T, Ward ST
Ann R Coll Surg Engl 2021 Nov;103(10):738-744. Epub 2021 Aug 26 doi: 10.1308/rcsann.2021.0044. PMID: 34436951Free PMC Article
Ghanem I, Castelo B, Jimenez-Fonseca P, Carmona-Bayonas A, Higuera O, Beato C, García T, Hernández R, Calderon C
Clin Transl Oncol 2020 Mar;22(3):330-336. Epub 2019 May 10 doi: 10.1007/s12094-019-02123-w. PMID: 31077086
Barquet-Muñoz SA, Cruz-Rodríguez E, Cantú De León DF, Isla-Ortiz D, Montalvo-Esquivel G, Herrera-Montalvo LA, Pérez-Plasencia C, Pérez-Montiel D, Herrera-Gómez Á
Rev Invest Clin 2017 Sep-Oct;69(5):286-292. doi: 10.24875/ric.17002143. PMID: 29077701
Xu KF, Feng R, Cui H, Tian X, Wang H, Zhao J, Huang H, Zhang W, Lo BH
Semin Respir Crit Care Med 2016 Jun;37(3):457-67. Epub 2016 May 27 doi: 10.1055/s-0036-1580690. PMID: 27231867

Diagnosis

Hutchins T
Tech Vasc Interv Radiol 2021 Sep;24(3):100769. Epub 2021 Sep 27 doi: 10.1016/j.tvir.2021.100769. PMID: 34861969
Kanber Y, Pusztaszeri M, Auger M
Cytopathology 2021 Sep;32(5):562-587. Epub 2021 Jun 3 doi: 10.1111/cyt.12993. PMID: 34033162
Guo M, Yu JJ, Perl AK, Wikenheiser-Brokamp KA, Riccetti M, Zhang EY, Sudha P, Adam M, Potter A, Kopras EJ, Giannikou K, Potter SS, Sherman S, Hammes SR, Kwiatkowski DJ, Whitsett JA, McCormack FX, Xu Y
Am J Respir Crit Care Med 2020 Nov 15;202(10):1373-1387. doi: 10.1164/rccm.201912-2445OC. PMID: 32603599Free PMC Article
Matsukuma KE, Yeh MM
Ann Diagn Pathol 2019 Feb;38:126-137. Epub 2018 Oct 12 doi: 10.1016/j.anndiagpath.2018.10.005. PMID: 30597357
Xu KF, Feng R, Cui H, Tian X, Wang H, Zhao J, Huang H, Zhang W, Lo BH
Semin Respir Crit Care Med 2016 Jun;37(3):457-67. Epub 2016 May 27 doi: 10.1055/s-0036-1580690. PMID: 27231867

Therapy

Martin AN, Kerwin MJ, Turrentine FE, Bauer TW, Adams RB, Stukenborg GJ, Zaydfudim VM
J Surg Res 2016 Nov;206(1):106-112. Epub 2016 Jul 15 doi: 10.1016/j.jss.2016.07.013. PMID: 27916348Free PMC Article
Etgen T, Steinich I, Gsottschneider L
J Stroke Cerebrovasc Dis 2014 Feb;23(2):361-6. Epub 2013 Jun 12 doi: 10.1016/j.jstrokecerebrovasdis.2013.05.004. PMID: 23763899
Simons JP, Hill JS, Ng SC, Shah SA, Zhou Z, Whalen GF, Tseng JF
Ann Surg 2009 Dec;250(6):929-34. doi: 10.1097/SLA.0b013e3181bc9c2f. PMID: 19855257
Chen M, Pennathur A, Luketich JD
Lasers Surg Med 2006 Jun;38(5):396-402. doi: 10.1002/lsm.20364. PMID: 16788924
Skoutelis AT, Dougenis D, Gogos CA, Bassaris HP
Eur J Cardiothorac Surg 1993;7(9):501-2. doi: 10.1016/1010-7940(93)90283-h. PMID: 8217231

Prognosis

Damron EP, Dono A, Chafi H, Martir M, Yu TK, Khwaja S, Amsbaugh M, Tandon N, Esquenazi Y, Blanco AI
World Neurosurg 2022 May;161:e210-e219. Epub 2022 Feb 3 doi: 10.1016/j.wneu.2022.01.109. PMID: 35123024
Kanber Y, Pusztaszeri M, Auger M
Cytopathology 2021 Sep;32(5):562-587. Epub 2021 Jun 3 doi: 10.1111/cyt.12993. PMID: 34033162
Guo M, Yu JJ, Perl AK, Wikenheiser-Brokamp KA, Riccetti M, Zhang EY, Sudha P, Adam M, Potter A, Kopras EJ, Giannikou K, Potter SS, Sherman S, Hammes SR, Kwiatkowski DJ, Whitsett JA, McCormack FX, Xu Y
Am J Respir Crit Care Med 2020 Nov 15;202(10):1373-1387. doi: 10.1164/rccm.201912-2445OC. PMID: 32603599Free PMC Article
Ghanem I, Castelo B, Jimenez-Fonseca P, Carmona-Bayonas A, Higuera O, Beato C, García T, Hernández R, Calderon C
Clin Transl Oncol 2020 Mar;22(3):330-336. Epub 2019 May 10 doi: 10.1007/s12094-019-02123-w. PMID: 31077086
Hart WR
Int J Gynecol Pathol 2005 Jan;24(1):4-25. PMID: 15626914

Clinical prediction guides

Damron EP, Dono A, Chafi H, Martir M, Yu TK, Khwaja S, Amsbaugh M, Tandon N, Esquenazi Y, Blanco AI
World Neurosurg 2022 May;161:e210-e219. Epub 2022 Feb 3 doi: 10.1016/j.wneu.2022.01.109. PMID: 35123024
Kanber Y, Pusztaszeri M, Auger M
Cytopathology 2021 Sep;32(5):562-587. Epub 2021 Jun 3 doi: 10.1111/cyt.12993. PMID: 34033162
Guo M, Yu JJ, Perl AK, Wikenheiser-Brokamp KA, Riccetti M, Zhang EY, Sudha P, Adam M, Potter A, Kopras EJ, Giannikou K, Potter SS, Sherman S, Hammes SR, Kwiatkowski DJ, Whitsett JA, McCormack FX, Xu Y
Am J Respir Crit Care Med 2020 Nov 15;202(10):1373-1387. doi: 10.1164/rccm.201912-2445OC. PMID: 32603599Free PMC Article
Ghanem I, Castelo B, Jimenez-Fonseca P, Carmona-Bayonas A, Higuera O, Beato C, García T, Hernández R, Calderon C
Clin Transl Oncol 2020 Mar;22(3):330-336. Epub 2019 May 10 doi: 10.1007/s12094-019-02123-w. PMID: 31077086
Marchevsky AM, Gupta R, Balzer B
Arch Pathol Lab Med 2010 Feb;134(2):194-206. doi: 10.5858/134.2.194. PMID: 20121607

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