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Heart aneurysm

MedGen UID:
42360
•Concept ID:
C0018789
•
Disease or Syndrome
Synonyms: Aneurysm, Cardiac; Aneurysm, Heart; Aneurysms, Cardiac; Aneurysms, Heart; Cardiac Aneurysm; Cardiac Aneurysms; Heart Aneurysm; Heart Aneurysms
SNOMED CT: Aneurysm of heart (65340007); Cardiac aneurysm (65340007)
 
Monarch Initiative: MONDO:0006779

Definition

A localized bulging or dilatation in the muscle wall of a heart (myocardium), usually in the left ventricle. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are hematoma caused by myocardial rupture. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHeart aneurysm

Professional guidelines

PubMed

Treatment of ischaemic heart disease complications.
Moll JW
Cor Vasa 1984;26(5):376-83. PMID: 6509993
SYSTOLIC MURMUR DEVELOPING AFTER MYOCARDIAL ISCHEMIA OR INFARCTION: DIFFERENTIAL DIAGNOSIS.
HOLLOWAY DH Jr, WHALEN RE, MCINTOSH HD
JAMA 1965 Mar 15;191:888-92. doi: 10.1001/jama.1965.03080110012002. PMID: 14260219
Rupture of congenital aneurysm of sinus of Valsava into right ventricle. Its diagnosis and treatment.
CH'EN HC, T'AO SC, SHIH MH, WAN TH
Chin Med J 1962 Dec;81:784-91. PMID: 14019800

Recent clinical studies

Etiology

In Utero Presentation of Left Ventricular Aneurysm.
Ansah DA, Lawrence EJ, Kearney DL, Qureshi AM
Neoreviews 2023 Aug 1;24(8):e530-e537. doi: 10.1542/neo.24-8-e530. PMID: 37525319
Outcome of submitral aneurysm.
Aggarwal P, Shrivastava A, Kuber D, Nath RK, Sinha SK, Kumar T, Raj A, Pandit BN
J Card Surg 2022 Sep;37(9):2673-2681. Epub 2022 Jun 7 doi: 10.1111/jocs.16663. PMID: 35671348
Left Ventricular Reconstruction for Postinfarction Left Ventricular Aneurysm: Review of Surgical Techniques.
Ruzza A, Czer LSC, Arabia F, Vespignani R, Esmailian F, Cheng W, De Robertis MA, Trento A
Tex Heart Inst J 2017 Oct;44(5):326-335. Epub 2017 Oct 1 doi: 10.14503/THIJ-16-6068. PMID: 29259502Free PMC Article
Left atrial appendage aneurysm: a systematic review of 82 cases.
Aryal MR, Hakim FA, Ghimire S, Ghimire S, Giri S, Pandit A, Bhandari Y, Bhandari N, Pathak R, Karmacharya P, Pradhan R
Echocardiography 2014 Nov;31(10):1312-8. Epub 2014 Jun 28 doi: 10.1111/echo.12667. PMID: 24976376
Right atrial appendage aneurysm: a systematic review.
Aryal MR, Hakim FA, Giri S, Ghimire S, Pandit A, Bhandari Y, Acharya YP, Pradhan R
Echocardiography 2014 Apr;31(4):534-9. Epub 2014 Jan 22 doi: 10.1111/echo.12510. PMID: 24447323

Diagnosis

Left atrial appendage aneurysm.
Jiang B, Wang X, Liu F, Song L
Interact Cardiovasc Thorac Surg 2020 Mar 1;30(3):495-496. doi: 10.1093/icvts/ivz283. PMID: 31773142
A Third Ventricle?
Ward CC, Schmidt GA
Ann Am Thorac Soc 2019 May;16(5):631-635. doi: 10.1513/AnnalsATS.201811-808CC. PMID: 31042095
Sub-mitral aneurysm.
Guimfacq V, Kemdem A, Vandenbossche JL
Eur Heart J 2009 Jan;30(1):43. Epub 2008 Jul 4 doi: 10.1093/eurheartj/ehn322. PMID: 18603622
Left-ventricular aneurysms: from disease to repair.
Antunes MJ, Antunes PE
Expert Rev Cardiovasc Ther 2005 Mar;3(2):285-94. doi: 10.1586/14779072.3.2.285. PMID: 15853602
Cardiac ventricular aneurysm.
Harley HR
Thorax 1969 Mar;24(2):148-72. doi: 10.1136/thx.24.2.148. PMID: 5821618Free PMC Article

Therapy

The Worth of a Miracle.
JAMA 2021 Feb 23;325(8):793. doi: 10.1001/jama.2020.17810. PMID: 33620392
Unusual Submitral Aneurysms.
Faria DC, Ribeiro R, Sousa-Uva M, Freitas A, Ferreira A, Soares AO, Borges Santos M, Gouveia R, Ramos S, Delgado Alves J, Augusto JB
Circ Cardiovasc Imaging 2020 Oct;13(10):e010466. Epub 2020 Sep 22 doi: 10.1161/CIRCIMAGING.120.010466. PMID: 32957799
Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke.
Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L, Arquizan C, Béjot Y, Vuillier F, Detante O, Guidoux C, Canaple S, Vaduva C, Dequatre-Ponchelle N, Sibon I, Garnier P, Ferrier A, Timsit S, Robinet-Borgomano E, Sablot D, Lacour JC, Zuber M, Favrole P, Pinel JF, Apoil M, Reiner P, Lefebvre C, Guérin P, Piot C, Rossi R, Dubois-Randé JL, Eicher JC, Meneveau N, Lusson JR, Bertrand B, Schleich JM, Godart F, Thambo JB, Leborgne L, Michel P, Pierard L, Turc G, Barthelet M, Charles-Nelson A, Weimar C, Moulin T, Juliard JM, Chatellier G; CLOSE Investigators
N Engl J Med 2017 Sep 14;377(11):1011-1021. doi: 10.1056/NEJMoa1705915. PMID: 28902593
Left atrial dissection.
Tsukui H, Iwasa S, Yamazaki K
Gen Thorac Cardiovasc Surg 2015 Aug;63(8):434-45. Epub 2015 May 24 doi: 10.1007/s11748-015-0562-7. PMID: 26003839
Heart diseases and stroke.
Sila CA
Curr Neurol Neurosci Rep 2006 Jan;6(1):23-7. doi: 10.1007/s11910-996-0005-z. PMID: 16469267

Prognosis

Left Ventricular Reconstruction Surgery in Candidates for Heart Transplantation.
Contreras CAM, Orellana PX, Almeida AFS, Finger MA, Rossi JM Neto, Chaccur P
Braz J Cardiovasc Surg 2019 Jun 1;34(3):265-270. doi: 10.21470/1678-9741-2018-0087. PMID: 31310463Free PMC Article
Left ventricular pseudo-pseudoaneurysm.
García-Lledó A, Moya Mur JL, García Segovia J
Rev Esp Cardiol (Engl Ed) 2015 Feb;68(2):147. Epub 2014 Jun 27 doi: 10.1016/j.rec.2014.02.027. PMID: 25623433
Right atrial appendage aneurysm: a systematic review.
Aryal MR, Hakim FA, Giri S, Ghimire S, Pandit A, Bhandari Y, Acharya YP, Pradhan R
Echocardiography 2014 Apr;31(4):534-9. Epub 2014 Jan 22 doi: 10.1111/echo.12510. PMID: 24447323
Prognosis for neonates with enterovirus myocarditis.
Freund MW, Kleinveld G, Krediet TG, van Loon AM, Verboon-Maciolek MA
Arch Dis Child Fetal Neonatal Ed 2010 May;95(3):F206-12. doi: 10.1136/adc.2009.165183. PMID: 20444813
Left ventricular pseudoaneurysm.
Frances C, Romero A, Grady D
J Am Coll Cardiol 1998 Sep;32(3):557-61. doi: 10.1016/s0735-1097(98)00290-3. PMID: 9741493

Clinical prediction guides

Clinical Characteristics and Prognostic Importance of Left Ventricular Apical Aneurysms in Hypertrophic Cardiomyopathy.
Lee DZJ, Montazeri M, Bataiosu R, Hoss S, Adler A, Nguyen ET, Rakowski H, Chan RH
JACC Cardiovasc Imaging 2022 Oct;15(10):1696-1711. Epub 2022 Jun 15 doi: 10.1016/j.jcmg.2022.03.029. PMID: 36202449
Outcome of submitral aneurysm.
Aggarwal P, Shrivastava A, Kuber D, Nath RK, Sinha SK, Kumar T, Raj A, Pandit BN
J Card Surg 2022 Sep;37(9):2673-2681. Epub 2022 Jun 7 doi: 10.1111/jocs.16663. PMID: 35671348
Mid-ventricular obstructive hypertrophic cardiomyopathy with apical aneurysm: An important subtype of arrhythmogenic cardiomyopathy.
Cui L, Tse G, Zhao Z, Bazoukis G, Letsas KP, Korantzopoulos P, Roever L, Li G, Liu T
Ann Noninvasive Electrocardiol 2019 Sep;24(5):e12638. Epub 2019 Feb 9 doi: 10.1111/anec.12638. PMID: 30737990Free PMC Article
Left atrial dissection.
Tsukui H, Iwasa S, Yamazaki K
Gen Thorac Cardiovasc Surg 2015 Aug;63(8):434-45. Epub 2015 May 24 doi: 10.1007/s11748-015-0562-7. PMID: 26003839
Periannular extension of infective endocarditis.
Kang N, Wan S, Ng CS, Underwood MJ
Ann Thorac Cardiovasc Surg 2009 Apr;15(2):74-81. PMID: 19471219

Recent systematic reviews

Vascular aneurysms in Ehlers-Danlos syndrome subtypes: A systematic review.
Shabani M, Abdollahi A, Brar BK, MacCarrick GL, Ambale Venkatesh B, Lima JAC, Bodurtha JN
Clin Genet 2023 Mar;103(3):261-267. Epub 2022 Oct 24 doi: 10.1111/cge.14245. PMID: 36210598
Atrial septal aneurysm contribution to the risk of cryptogenic stroke in patients with patent foramen ovale: A brief updated systematic review and meta-analysis.
Rigatelli G, Zuin M, Bilato C
Trends Cardiovasc Med 2023 Aug;33(6):329-333. Epub 2022 Feb 15 doi: 10.1016/j.tcm.2022.02.006. PMID: 35181471
Left atrial appendage aneurysm: a systematic review of 82 cases.
Aryal MR, Hakim FA, Ghimire S, Ghimire S, Giri S, Pandit A, Bhandari Y, Bhandari N, Pathak R, Karmacharya P, Pradhan R
Echocardiography 2014 Nov;31(10):1312-8. Epub 2014 Jun 28 doi: 10.1111/echo.12667. PMID: 24976376
Characteristics and outcome of primary congenital left ventricular aneurysm and diverticulum: analysis of cases from the literature.
Ohlow MA, Brunelli M, Lauer B
Prenat Diagn 2014 Sep;34(9):893-9. Epub 2014 May 15 doi: 10.1002/pd.4389. PMID: 24752829
Right atrial appendage aneurysm: a systematic review.
Aryal MR, Hakim FA, Giri S, Ghimire S, Pandit A, Bhandari Y, Acharya YP, Pradhan R
Echocardiography 2014 Apr;31(4):534-9. Epub 2014 Jan 22 doi: 10.1111/echo.12510. PMID: 24447323

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