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Renovascular hypertension

MedGen UID:
43786
Concept ID:
C0020545
Disease or Syndrome
Synonyms: Hypertension, Renovascular; Renovascular Hypertension
SNOMED CT: Hypertension due to renovascular disease (123799005); Renovascular hypertension (123799005)
 
HPO: HP:0100817
Monarch Initiative: MONDO:0006947

Definition

The presence of hypertension related to stenosis of the renal artery. [from HPO]

Conditions with this feature

Fibromuscular dysplasia
MedGen UID:
4700
Concept ID:
C0016052
Disease or Syndrome
Fibromuscular dysplasia (FMDA) is a nonatherosclerotic, noninflammatory arterial disease that most commonly involves the renal and carotid arteries. The prevalence of symptomatic renal artery FMDA is about 4 in 1,000 and the prevalence of cervicocranial FMDA is about half of that. Histologic classification includes 3 main subtypes, intimal, medial, and perimedial, which may be associated in a single patient. Angiographic classification includes the multifocal type, with multiple stenoses and the 'string of beads' appearance that is related to medial FMDA, and tubular and focal types, which are not clearly related to specific histologic lesions (summary by Plouin et al., 2007)
Autosomal recessive inherited pseudoxanthoma elasticum
MedGen UID:
698415
Concept ID:
C1275116
Disease or Syndrome
Pseudoxanthoma elasticum (PXE) is a systemic disorder that affects the elastic tissue of the skin, the eye, and vascular system. Individuals most commonly present with angioid streaks of the retina found on routine eye examination or associated with retinal hemorrhage and/or characteristic papules in the skin. The most frequent cause of morbidity and disability in PXE is reduced vision due to complications of subretinal neovascularizations and macular atrophy. Other manifestations include premature gastrointestinal angina and/or bleeding, intermittent claudication of arm and leg muscles, stroke, renovascular hypertension, and cardiovascular complications (angina/myocardial infarction). Most affected individuals live a normal life span.
Grange syndrome
MedGen UID:
355427
Concept ID:
C1865267
Disease or Syndrome
Grange syndrome (GRNG) is a rare early-onset disease characterized by hypertension and multifocal stenoocclusive lesions of renal, cerebral, and abdominal arteries. Bone fragility, syndactyly, brachydactyly, congenital heart defects, and learning disabilities have been reported with variable expressivity and incomplete penetrance (summary by Rath et al., 2019).

Professional guidelines

PubMed

Sarathy H, Salman LA, Lee C, Cohen JB
Med Clin North Am 2022 Mar;106(2):269-283. Epub 2022 Feb 2 doi: 10.1016/j.mcna.2021.11.004. PMID: 35227430Free PMC Article
Rossi GP, Bisogni V, Rossitto G, Maiolino G, Cesari M, Zhu R, Seccia TM
High Blood Press Cardiovasc Prev 2020 Dec;27(6):547-560. Epub 2020 Nov 7 doi: 10.1007/s40292-020-00415-9. PMID: 33159664Free PMC Article
Gornik HL, Persu A, Adlam D, Aparicio LS, Azizi M, Boulanger M, Bruno RM, de Leeuw P, Fendrikova-Mahlay N, Froehlich J, Ganesh SK, Gray BH, Jamison C, Januszewicz A, Jeunemaitre X, Kadian-Dodov D, Kim ES, Kovacic JC, Mace P, Morganti A, Sharma A, Southerland AM, Touzé E, van der Niepen P, Wang J, Weinberg I, Wilson S, Olin JW, Plouin PF
Vasc Med 2019 Apr;24(2):164-189. Epub 2019 Jan 16 doi: 10.1177/1358863X18821816. PMID: 30648921

Recent clinical studies

Etiology

Rossi GP, Bisogni V, Rossitto G, Maiolino G, Cesari M, Zhu R, Seccia TM
High Blood Press Cardiovasc Prev 2020 Dec;27(6):547-560. Epub 2020 Nov 7 doi: 10.1007/s40292-020-00415-9. PMID: 33159664Free PMC Article
Textor SC
Curr Opin Cardiol 2020 Nov;35(6):627-635. doi: 10.1097/HCO.0000000000000790. PMID: 32852347
Tziomalos K
Curr Hypertens Rev 2020;16(1):11. doi: 10.2174/1573402115666190416161116. PMID: 31038070
Boutari C, Georgianou E, Sachinidis A, Katsimardou A, Christou K, Piperidou A, Karagiannis A
Curr Hypertens Rev 2020;16(1):24-29. doi: 10.2174/1573402115666190416153321. PMID: 31038069
Tafur-Soto JD, White CJ
Cardiol Clin 2015 Feb;33(1):59-73. doi: 10.1016/j.ccl.2014.09.006. PMID: 25439331

Diagnosis

de Oliveira Campos JL, Bitencourt L, Pedrosa AL, Silva DF, Lin FJJ, de Oliveira Dias LT, Simões E Silva AC
Pediatr Nephrol 2021 Dec;36(12):3853-3868. Epub 2021 Apr 13 doi: 10.1007/s00467-021-05063-2. PMID: 33851262
Mannemuddhu SS, Ojeda JC, Yadav A
Prim Care 2020 Dec;47(4):631-644. Epub 2020 Oct 1 doi: 10.1016/j.pop.2020.08.009. PMID: 33121633
Textor SC
Curr Opin Cardiol 2020 Nov;35(6):627-635. doi: 10.1097/HCO.0000000000000790. PMID: 32852347
Tziomalos K
Curr Hypertens Rev 2020;16(1):11. doi: 10.2174/1573402115666190416161116. PMID: 31038070
Tafur-Soto JD, White CJ
Cardiol Clin 2015 Feb;33(1):59-73. doi: 10.1016/j.ccl.2014.09.006. PMID: 25439331

Therapy

Carey RM, Wright JT Jr, Taler SJ, Whelton PK
Circ Res 2021 Apr 2;128(7):827-846. Epub 2021 Apr 1 doi: 10.1161/CIRCRESAHA.121.318083. PMID: 33793326Free PMC Article
Textor SC
Curr Opin Cardiol 2020 Nov;35(6):627-635. doi: 10.1097/HCO.0000000000000790. PMID: 32852347
Prince M, Gupta A, Bob-Manuel T, Tafur J
Prog Cardiovasc Dis 2020 Jan-Feb;63(1):58-63. Epub 2019 Dec 7 doi: 10.1016/j.pcad.2019.12.001. PMID: 31821813
Boutari C, Georgianou E, Sachinidis A, Katsimardou A, Christou K, Piperidou A, Karagiannis A
Curr Hypertens Rev 2020;16(1):24-29. doi: 10.2174/1573402115666190416153321. PMID: 31038069
Tafur-Soto JD, White CJ
Cardiol Clin 2015 Feb;33(1):59-73. doi: 10.1016/j.ccl.2014.09.006. PMID: 25439331

Prognosis

Tziomalos K
Curr Hypertens Rev 2020;16(1):11. doi: 10.2174/1573402115666190416161116. PMID: 31038070
Bakris GL
Am J Med 2003 Dec 8;115 Suppl 8A:49S-54S. doi: 10.1016/j.amjmed.2003.08.013. PMID: 14678866
O'Neill JA Jr
Semin Pediatr Surg 1994 May;3(2):114-23. PMID: 8062055
Goble MM
Pediatr Clin North Am 1993 Feb;40(1):105-22. doi: 10.1016/s0031-3955(16)38484-x. PMID: 8417399
Ram CV
Cardiol Clin 1988 Nov;6(4):483-508. PMID: 3067842

Clinical prediction guides

Rossi GP, Bisogni V, Rossitto G, Maiolino G, Cesari M, Zhu R, Seccia TM
High Blood Press Cardiovasc Prev 2020 Dec;27(6):547-560. Epub 2020 Nov 7 doi: 10.1007/s40292-020-00415-9. PMID: 33159664Free PMC Article
Textor SC
Curr Opin Cardiol 2020 Nov;35(6):627-635. doi: 10.1097/HCO.0000000000000790. PMID: 32852347
Gornik HL, Persu A, Adlam D, Aparicio LS, Azizi M, Boulanger M, Bruno RM, de Leeuw P, Fendrikova-Mahlay N, Froehlich J, Ganesh SK, Gray BH, Jamison C, Januszewicz A, Jeunemaitre X, Kadian-Dodov D, Kim ES, Kovacic JC, Mace P, Morganti A, Sharma A, Southerland AM, Touzé E, van der Niepen P, Wang J, Weinberg I, Wilson S, Olin JW, Plouin PF
Vasc Med 2019 Apr;24(2):164-189. Epub 2019 Jan 16 doi: 10.1177/1358863X18821816. PMID: 30648921
Smith A, Gaba RC, Bui JT, Minocha J
Tech Vasc Interv Radiol 2016 Sep;19(3):211-7. Epub 2016 Jun 3 doi: 10.1053/j.tvir.2016.06.006. PMID: 27641455
Textor SC, Lerman L
Am J Hypertens 2010 Nov;23(11):1159-69. Epub 2010 Sep 23 doi: 10.1038/ajh.2010.174. PMID: 20864945Free PMC Article

Recent systematic reviews

Tian Y, Yuan B, Zhang N, Huang Z
Ann Vasc Surg 2022 Jan;78:362-372. Epub 2021 Sep 17 doi: 10.1016/j.avsg.2021.06.042. PMID: 34543714
Mudalige NL, Ranasinghe C, Stojanovic J
Pediatr Nephrol 2022 Jan;37(1):49-59. Epub 2021 Jul 8 doi: 10.1007/s00467-021-05165-x. PMID: 34240276
Elliott WJ, Bistrika EA
Expert Opin Drug Saf 2018 Feb;17(2):207-216. Epub 2017 Oct 31 doi: 10.1080/14740338.2018.1397129. PMID: 29065722
Trinquart L, Mounier-Vehier C, Sapoval M, Gagnon N, Plouin PF
Hypertension 2010 Sep;56(3):525-32. Epub 2010 Jul 12 doi: 10.1161/HYPERTENSIONAHA.110.152918. PMID: 20625080
de Mast Q, Beutler JJ
J Hypertens 2009 Jul;27(7):1333-40. doi: 10.1097/HJH.0b013e328329bbf4. PMID: 19365285

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