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Dissociated sensory loss

MedGen UID:
451034
•Concept ID:
C0278136
•
Finding; Finding
SNOMED CT: Dissociated sensory loss (87275002)
 
HPO: HP:0010835

Definition

A pattern of sensory loss with selective loss of touch sensation and proprioception without loss of pain and temperature, or vice-versa. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDissociated sensory loss

Professional guidelines

PubMed

Diagnostic Criteria for Small Fiber Neuropathy.
Blackmore D, Siddiqi ZA
J Clin Neuromuscul Dis 2017 Mar;18(3):125-131. doi: 10.1097/CND.0000000000000154. PMID: 28221302

Recent clinical studies

Etiology

Primary B-cell Spinal Cord Lymphoma of the Cervical Spine.
Guzik G
Ortop Traumatol Rehabil 2018 Jun 30;20(3):219-227. doi: 10.5604/01.3001.0012.2131. PMID: 30152771
Diagnostic Criteria for Small Fiber Neuropathy.
Blackmore D, Siddiqi ZA
J Clin Neuromuscul Dis 2017 Mar;18(3):125-131. doi: 10.1097/CND.0000000000000154. PMID: 28221302
Dissociated sensory loss in diabetic autonomic neuropathy.
Winkler AS, Ejskjaer N, Edmonds M, Watkins PJ
Diabet Med 2000 Jun;17(6):457-62. doi: 10.1046/j.1464-5491.2000.00298.x. PMID: 10975215
Pure sensory syndromes in thalamic stroke.
Paciaroni M, Bogousslavsky J
Eur Neurol 1998;39(4):211-7. doi: 10.1159/000007936. PMID: 9635471
Neuropathies associated with monoclonal gammopathies.
Kissel JT, Mendell JR
Neuromuscul Disord 1996 Jan;6(1):3-18. doi: 10.1016/0960-8966(95)00021-6. PMID: 8845716

Diagnosis

Diagnostic Criteria for Small Fiber Neuropathy.
Blackmore D, Siddiqi ZA
J Clin Neuromuscul Dis 2017 Mar;18(3):125-131. doi: 10.1097/CND.0000000000000154. PMID: 28221302
Insights gained into pain processing from patients with focal brain lesions.
Garcia-Larrea L
Neurosci Lett 2012 Jun 29;520(2):188-91. Epub 2012 May 10 doi: 10.1016/j.neulet.2012.05.007. PMID: 22579692
Laser evoked potentials for assessing sensory neuropathy in human patients.
Truini A, Romaniello A, Galeotti F, Iannetti GD, Cruccu G
Neurosci Lett 2004 May 6;361(1-3):25-8. doi: 10.1016/j.neulet.2003.12.008. PMID: 15135884
Sensory loss in syringomyelia: not necessarily dissociated.
Honan WP, Williams B
J R Soc Med 1993 Sep;86(9):519-20. PMID: 8410888Free PMC Article
Management of hydromyelia.
Wisoff JH, Epstein F
Neurosurgery 1989 Oct;25(4):562-71. doi: 10.1097/00006123-198910000-00009. PMID: 2797394

Therapy

Primary B-cell Spinal Cord Lymphoma of the Cervical Spine.
Guzik G
Ortop Traumatol Rehabil 2018 Jun 30;20(3):219-227. doi: 10.5604/01.3001.0012.2131. PMID: 30152771
Anterior spinal cord infarct: a rare yet disabling stroke.
Davda N, Osman C
BMJ Case Rep 2018 May 7;2018 doi: 10.1136/bcr-2017-221655. PMID: 29735490Free PMC Article
Mechanisms and prevention of anterior spinal artery syndrome following abdominal aortic surgery.
Aydin A
Angiol Sosud Khir 2015;21(1):155-64. PMID: 25757179
A case of spontaneous spinal epidural hematoma mimicking a stroke.
Son S, Kang DH, Choi DS, Kim SK, Lim BH, Choi NC
Neurologist 2012 Jan;18(1):41-3. doi: 10.1097/NRL.0b013e31823d7ade. PMID: 22217615
Anterior spinal artery syndrome.
Baba H, Tomita K, Kawagishi T, Imura S
Int Orthop 1993 Dec;17(6):353-6. doi: 10.1007/BF00180453. PMID: 8163309

Prognosis

Interlayer dural split technique for Chiari I malformation treatment in adult-Technical note.
Florian IA, Pop MM, Timiș TL, Florian IS
Int J Clin Pract 2021 Jul;75(7):e14148. Epub 2021 Mar 21 doi: 10.1111/ijcp.14148. PMID: 33709500
Dissociated sensory loss and muscle wasting in a young male with headaches: syringomyelia with type 1 Arnold-Chiari malformation.
Waqar M, Vohra AH
BMJ Case Rep 2013 Oct 29;2013 doi: 10.1136/bcr-2013-201708. PMID: 24169873Free PMC Article
Pure intramedullary spinal cord metastasis secondary to gastric cancer.
Gazzeri R, Galarza M, Faiola A, Gazzeri G
Neurosurg Rev 2006 Apr;29(2):173-7. Epub 2006 Feb 8 doi: 10.1007/s10143-005-0015-3. PMID: 16465555
Laser evoked potentials for assessing sensory neuropathy in human patients.
Truini A, Romaniello A, Galeotti F, Iannetti GD, Cruccu G
Neurosci Lett 2004 May 6;361(1-3):25-8. doi: 10.1016/j.neulet.2003.12.008. PMID: 15135884
Recurrent optic neuromyelitis with endocrinopathies: a new syndrome.
Vernant JC, Cabre P, Smadja D, Merle H, Caubarrère I, Mikol J, Poser CM
Neurology 1997 Jan;48(1):58-64. doi: 10.1212/wnl.48.1.58. PMID: 9008495

Clinical prediction guides

Laser evoked potentials for assessing sensory neuropathy in human patients.
Truini A, Romaniello A, Galeotti F, Iannetti GD, Cruccu G
Neurosci Lett 2004 May 6;361(1-3):25-8. doi: 10.1016/j.neulet.2003.12.008. PMID: 15135884
Anterior spinal artery syndrome complicated by the ondine curse.
Manconi M, Mondini S, Fabiani A, Rossi P, Ambrosetto P, Cirignotta F
Arch Neurol 2003 Dec;60(12):1787-90. doi: 10.1001/archneur.60.12.1787. PMID: 14676058
Dissociated sensory loss in diabetic autonomic neuropathy.
Winkler AS, Ejskjaer N, Edmonds M, Watkins PJ
Diabet Med 2000 Jun;17(6):457-62. doi: 10.1046/j.1464-5491.2000.00298.x. PMID: 10975215
The contribution of median nerve SEPs in the functional assessment of the cervical spinal cord in syringomyelia. A study of 24 patients.
Restuccia D, Mauguière F
Brain 1991 Feb;114 ( Pt 1B):361-79. doi: 10.1093/brain/114.1.361. PMID: 2004247
Laser-evoked cerebral potentials in the assessment of cutaneous pain sensitivity in normal subjects and patients.
Bromm B, Treede RD
Rev Neurol (Paris) 1991;147(10):625-43. PMID: 1763252

Recent systematic reviews

Charcot arthropathy of elbow due to syringomyelia: a case series and systematic review of literature.
Parida MK, Pattanaik SS, Panda AK, Das BK, Tripathy SR
Clin Rheumatol 2023 Jan;42(1):261-268. Epub 2022 Aug 22 doi: 10.1007/s10067-022-06332-7. PMID: 35994178

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