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Angiocentric glioma

MedGen UID:
453267
•Concept ID:
C2363903
•
Neoplastic Process
Synonyms: Angiocentric Glioma; angiocentric glioma; Angiocentric Glioma (WHO Grade 1); Angiocentric Glioma (WHO Grade I); angiocentric glioma (WHO grade I); Angiocentric Neuroepithelial Tumor; angiocentric neuroepithelial tumor; angiocentric neuroepithelial tumour; ANGL; Monomorphus Angiocentric Glioma; Monomorphus angiocentric glioma
SNOMED CT: Angiocentric glioma (450900009)
 
Monarch Initiative: MONDO:0016705
Orphanet: ORPHA251671

Definition

An extremely rare slow-growing glial neoplasm of the central nervous system, usually arising in a superficial location in the cerebrum, affecting all ages and both sexes, and characterized by intractable seizures and headaches, with most cases being cured by surgical incision alone and therefore having a good prognosis. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAngiocentric glioma
Follow this link to review classifications for Angiocentric glioma in Orphanet.

Professional guidelines

PubMed

Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
Lake JA, Donson AM, Prince E, Davies KD, Nellan A, Green AL, Mulcahy Levy J, Dorris K, Vibhakar R, Hankinson TC, Foreman NK, Ewalt MD, Kleinschmidt-DeMasters BK, Hoffman LM, Gilani A
Pediatr Blood Cancer 2020 Jan;67(1):e28028. Epub 2019 Oct 8 doi: 10.1002/pbc.28028. PMID: 31595628Free PMC Article

Recent clinical studies

Etiology

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Paediatric-type diffuse low-grade gliomas: a clinically and biologically distinct group of tumours with a favourable outcome.
Fabbri VP, Caporalini C, Asioli S, Buccoliero A
Pathologica 2022 Dec;114(6):410-421. doi: 10.32074/1591-951X-828. PMID: 36534420Free PMC Article
MYB-QKI rearrangement in angiocentric glioma.
Lian F, Wang LM, Qi XL, Liu LN, Wang XF, Fu J, Xiong J, Lu DH, Piao YS
Clin Neuropathol 2020 Nov/Dec;39(6):263-270. doi: 10.5414/NP301284. PMID: 32589128
Characterization of gliomas: from morphology to molecules.
Ferris SP, Hofmann JW, Solomon DA, Perry A
Virchows Arch 2017 Aug;471(2):257-269. Epub 2017 Jul 4 doi: 10.1007/s00428-017-2181-4. PMID: 28674742
The 2007 WHO classification of tumours of the central nervous system.
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P
Acta Neuropathol 2007 Aug;114(2):97-109. Epub 2007 Jul 6 doi: 10.1007/s00401-007-0243-4. PMID: 17618441Free PMC Article

Diagnosis

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
MYB/MYBL1::QKI fusion-positive diffuse glioma.
Suh YY, Lee K, Shim YM, Phi JH, Park CK, Kim SK, Choi SH, Yun H, Park SH
J Neuropathol Exp Neurol 2023 Feb 21;82(3):250-260. doi: 10.1093/jnen/nlac123. PMID: 36592415Free PMC Article
Angiocentric glioma of brainstem.
Almubarak AO, Alahmari A, Al Hindi H, AlShail E
Neurosciences (Riyadh) 2020 Oct;25(5):416-420. doi: 10.17712/nsj.2020.5.20200026. PMID: 33459294Free PMC Article
Low-grade developmental and epilepsy associated brain tumors: a critical update 2020.
Slegers RJ, Blumcke I
Acta Neuropathol Commun 2020 Mar 9;8(1):27. doi: 10.1186/s40478-020-00904-x. PMID: 32151273Free PMC Article
Rare glial tumors.
Soffietti R, Rudà R, Reardon D
Handb Clin Neurol 2016;134:399-415. doi: 10.1016/B978-0-12-802997-8.00024-4. PMID: 26948368

Therapy

The epileptology of Koolen-de Vries syndrome: Electro-clinico-radiologic findings in 31 patients.
Myers KA, Mandelstam SA, Ramantani G, Rushing EJ, de Vries BB, Koolen DA, Scheffer IE
Epilepsia 2017 Jun;58(6):1085-1094. Epub 2017 Apr 25 doi: 10.1111/epi.13746. PMID: 28440867
Malignant glioma with angiocentric features.
Lu JQ, Patel S, Wilson BA, Pugh J, Mehta V
J Neurosurg Pediatr 2013 Mar;11(3):350-5. Epub 2012 Dec 14 doi: 10.3171/2012.11.PEDS12234. PMID: 23240849
Imaging characteristics of an unusual, high-grade angiocentric glioma: a case report and review of the literature.
Aguilar HN, Hung RW, Mehta V, Kotylak T
J Radiol Case Rep 2012 Oct;6(10):1-10. Epub 2012 Oct 1 doi: 10.3941/jrcr.v6i10.1134. PMID: 23378871Free PMC Article

Prognosis

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Angiocentric glioma: A case report and review of the literature.
Wang H, Zhu J, Zhu P, Luo C
J Clin Neurosci 2021 Dec;94:179-185. Epub 2021 Oct 28 doi: 10.1016/j.jocn.2021.10.016. PMID: 34863434
Angiocentric glioma of brainstem.
Almubarak AO, Alahmari A, Al Hindi H, AlShail E
Neurosciences (Riyadh) 2020 Oct;25(5):416-420. doi: 10.17712/nsj.2020.5.20200026. PMID: 33459294Free PMC Article
Characterization of gliomas: from morphology to molecules.
Ferris SP, Hofmann JW, Solomon DA, Perry A
Virchows Arch 2017 Aug;471(2):257-269. Epub 2017 Jul 4 doi: 10.1007/s00428-017-2181-4. PMID: 28674742
Rare glial tumors.
Soffietti R, Rudà R, Reardon D
Handb Clin Neurol 2016;134:399-415. doi: 10.1016/B978-0-12-802997-8.00024-4. PMID: 26948368

Clinical prediction guides

Neuroimaging features of angiocentric glioma: A case series and systematic review.
Kurokawa R, Baba A, Emile P, Kurokawa M, Ota Y, Kim J, Capizzano A, Srinivasan A, Moritani T
J Neuroimaging 2022 May;32(3):389-399. Epub 2022 Feb 24 doi: 10.1111/jon.12983. PMID: 35201652Free PMC Article
Angiocentric glioma-associated seizures: The possible role of EATT2, pyruvate carboxylase and glutamine synthetase.
Buccoliero AM, Caporalini C, Scagnet M, Mussa F, Giordano F, Sardi I, Migliastro I, Moscardi S, Conti V, Barba C, Antonelli M, Gianno F, Rossi S, Diomedi-Camassei F, Gessi M, Donofrio V, Bertero L, Giangaspero F, Santi M, Aronica E, Genitori L, Guerrini R
Seizure 2021 Mar;86:152-154. Epub 2021 Feb 16 doi: 10.1016/j.seizure.2021.02.014. PMID: 33621827
Cystic angiocentric glioma: a case report and literature review.
Wang Q, Xiong Y, Chen J, Shao Q
Childs Nerv Syst 2021 Aug;37(8):2701-2705. Epub 2020 Sep 26 doi: 10.1007/s00381-020-04882-2. PMID: 32979070
MYB-QKI rearrangement in angiocentric glioma.
Lian F, Wang LM, Qi XL, Liu LN, Wang XF, Fu J, Xiong J, Lu DH, Piao YS
Clin Neuropathol 2020 Nov/Dec;39(6):263-270. doi: 10.5414/NP301284. PMID: 32589128
Characterization of gliomas: from morphology to molecules.
Ferris SP, Hofmann JW, Solomon DA, Perry A
Virchows Arch 2017 Aug;471(2):257-269. Epub 2017 Jul 4 doi: 10.1007/s00428-017-2181-4. PMID: 28674742

Recent systematic reviews

Neuroimaging features of angiocentric glioma: A case series and systematic review.
Kurokawa R, Baba A, Emile P, Kurokawa M, Ota Y, Kim J, Capizzano A, Srinivasan A, Moritani T
J Neuroimaging 2022 May;32(3):389-399. Epub 2022 Feb 24 doi: 10.1111/jon.12983. PMID: 35201652Free PMC Article

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