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Stage II Small Intestinal Gastrointestinal Stromal Tumor

MedGen UID:
453643
•Concept ID:
C2981416
•
Neoplastic Process
Synonym: Stage II Small Intestinal Gastrointestinal Stromal Tumor AJCC v7

Definition

Stage II includes: T3, N0, M0, Mitotic rate: Low. T3: Tumor more than 5 cm, but not more than 10 cm, in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 7th ed.) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage II Small Intestinal Gastrointestinal Stromal Tumor

Recent clinical studies

Etiology

Gastrointestinal stromal tumors. A clinicopathological study.
Alghamdi HM, Amr SS, Shawarby MA, Sheikh SS, Alsayyah AA, Alamri AM, Ismail MH, Almarhabi A, Alrefaee MA, Ahmed MI
Saudi Med J 2019 Feb;40(2):126-130. doi: 10.15537/smj.2019.2.23913. PMID: 30723856Free PMC Article
Laparoscopic versus open resection of gastrointestinal stromal tumors: survival outcomes from the NCDB.
Inaba CS, Dosch A, Koh CY, Sujatha-Bhaskar S, Pejcinovska M, Smith BR, Nguyen NT
Surg Endosc 2019 Mar;33(3):923-932. Epub 2018 Aug 31 doi: 10.1007/s00464-018-6393-8. PMID: 30171396
Review of a non-epithelial tumour of the small bowel after c-kit revolution.
Fiori E, Ferraro D, De Cesare A, Leone G, Barmann C, Schillaci A, Borrini F
Ann Ital Chir 2016;87:183-5. PMID: 27179285
From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary. Part II.
Young RH
Adv Anat Pathol 2007 May;14(3):149-77. doi: 10.1097/PAP.0b013e3180504abf. PMID: 17452813
Malignant gastrointestinal stromal tumors of the small intestine: a review of 50 cases from a prospective database.
Crosby JA, Catton CN, Davis A, Couture J, O'Sullivan B, Kandel R, Swallow CJ
Ann Surg Oncol 2001 Jan-Feb;8(1):50-9. doi: 10.1007/s10434-001-0050-4. PMID: 11206225

Diagnosis

Gastrointestinal stromal tumors. A clinicopathological study.
Alghamdi HM, Amr SS, Shawarby MA, Sheikh SS, Alsayyah AA, Alamri AM, Ismail MH, Almarhabi A, Alrefaee MA, Ahmed MI
Saudi Med J 2019 Feb;40(2):126-130. doi: 10.15537/smj.2019.2.23913. PMID: 30723856Free PMC Article
From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary. Part II.
Young RH
Adv Anat Pathol 2007 May;14(3):149-77. doi: 10.1097/PAP.0b013e3180504abf. PMID: 17452813
Small bowel cancer: single-centre results over a period of 12 years.
Egberts JH, Scharrer ML, Hinz S, Schafmayer C, Klomp HJ, Faendrich F, Tepel J
Hepatogastroenterology 2007 Jan-Feb;54(73):129-34. PMID: 17419246
Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: a case report.
Escobar GA, Robinson WA, Nydam TL, Heiple DC, Weiss GJ, Buckley L, Gonzalez R, McCarter MD
BMC Cancer 2007 Jan 17;7:13. doi: 10.1186/1471-2407-7-13. PMID: 17229322Free PMC Article
Malignant gastrointestinal stromal tumors of the small intestine: a review of 50 cases from a prospective database.
Crosby JA, Catton CN, Davis A, Couture J, O'Sullivan B, Kandel R, Swallow CJ
Ann Surg Oncol 2001 Jan-Feb;8(1):50-9. doi: 10.1007/s10434-001-0050-4. PMID: 11206225

Therapy

Laparoscopic versus open resection of gastrointestinal stromal tumors: survival outcomes from the NCDB.
Inaba CS, Dosch A, Koh CY, Sujatha-Bhaskar S, Pejcinovska M, Smith BR, Nguyen NT
Surg Endosc 2019 Mar;33(3):923-932. Epub 2018 Aug 31 doi: 10.1007/s00464-018-6393-8. PMID: 30171396
Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: a case report.
Escobar GA, Robinson WA, Nydam TL, Heiple DC, Weiss GJ, Buckley L, Gonzalez R, McCarter MD
BMC Cancer 2007 Jan 17;7:13. doi: 10.1186/1471-2407-7-13. PMID: 17229322Free PMC Article

Prognosis

Review of a non-epithelial tumour of the small bowel after c-kit revolution.
Fiori E, Ferraro D, De Cesare A, Leone G, Barmann C, Schillaci A, Borrini F
Ann Ital Chir 2016;87:183-5. PMID: 27179285
Small bowel cancer: single-centre results over a period of 12 years.
Egberts JH, Scharrer ML, Hinz S, Schafmayer C, Klomp HJ, Faendrich F, Tepel J
Hepatogastroenterology 2007 Jan-Feb;54(73):129-34. PMID: 17419246
Malignant gastrointestinal stromal tumors of the small intestine: a review of 50 cases from a prospective database.
Crosby JA, Catton CN, Davis A, Couture J, O'Sullivan B, Kandel R, Swallow CJ
Ann Surg Oncol 2001 Jan-Feb;8(1):50-9. doi: 10.1007/s10434-001-0050-4. PMID: 11206225

Clinical prediction guides

Laparoscopic versus open resection of gastrointestinal stromal tumors: survival outcomes from the NCDB.
Inaba CS, Dosch A, Koh CY, Sujatha-Bhaskar S, Pejcinovska M, Smith BR, Nguyen NT
Surg Endosc 2019 Mar;33(3):923-932. Epub 2018 Aug 31 doi: 10.1007/s00464-018-6393-8. PMID: 30171396
Malignant gastrointestinal stromal tumors of the small intestine: a review of 50 cases from a prospective database.
Crosby JA, Catton CN, Davis A, Couture J, O'Sullivan B, Kandel R, Swallow CJ
Ann Surg Oncol 2001 Jan-Feb;8(1):50-9. doi: 10.1007/s10434-001-0050-4. PMID: 11206225

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