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Bacteremia, susceptibility to, 1(BACTS1)

MedGen UID:
482275
•Concept ID:
C3280645
•
Finding
Synonym: BACTS1
 
Gene (location): TIRAP (11q24.2)
 
Monarch Initiative: MONDO:0013723
OMIM®: 614382

Definition

Any bacteremia, susceptibility in which the cause of the disease is a mutation in the TIRAP gene. [from MONDO]

Professional guidelines

PubMed

Post-treatment outcomes of ceftriaxone versus antistaphylococcal penicillins or cefazolin for definitive therapy of methicillin-susceptible Staphylococcus aureus bacteremia.
Yetmar ZA, Khodadadi RB, Go JR, Chesdachai S, Abu Saleh OM
Eur J Clin Microbiol Infect Dis 2023 Apr;42(4):423-430. Epub 2023 Feb 17 doi: 10.1007/s10096-023-04575-z. PMID: 36800065
Cefazolin in the treatment of central nervous system infections: A narrative review and recommendation.
Antosz K, Battle S, Chang J, Scheetz MH, Al-Hasan M, Bookstaver PB
Pharmacotherapy 2023 Jan;43(1):85-95. Epub 2023 Jan 22 doi: 10.1002/phar.2750. PMID: 36521869
Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group.
Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, Bolger A, Cabell CH, Takahashi M, Baltimore RS, Newburger JW, Strom BL, Tani LY, Gerber M, Bonow RO, Pallasch T, Shulman ST, Rowley AH, Burns JC, Ferrieri P, Gardner T, Goff D, Durack DT; American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee; American Heart Association Council on Cardiovascular Disease in the Young; American Heart Association Council on Clinical Cardiology; American Heart Association Council on Cardiovascular Surgery and Anesthesia; Quality of Care and Outcomes Research Interdisciplinary Working Group
Circulation 2007 Oct 9;116(15):1736-54. Epub 2007 Apr 19 doi: 10.1161/CIRCULATIONAHA.106.183095. PMID: 17446442

Recent clinical studies

Etiology

Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial.
Omrani AS, Abujarir SH, Ben Abid F, Shaar SH, Yilmaz M, Shaukat A, Alsamawi MS, Elgara MS, Alghazzawi MI, Shunnar KM, Zaqout A, Aldeeb YM, Alfouzan W, Almaslamani MA; SOAB Study Group
Clin Microbiol Infect 2024 Apr;30(4):492-498. Epub 2023 Oct 18 doi: 10.1016/j.cmi.2023.10.014. PMID: 37858867
Bacteremia in Children with Solid Tumors: Etiology, Antimicrobial Susceptibility, Factors Associated with Multidrug Resistance, and Mortality.
Ginzburg A, Goldstein G, Raviv D, Cohen H, Weinreb S, Harlev D, Nitsan-Luques A, Abou Saoud MY, Strahilevitz J, Averbuch D
Microb Drug Resist 2022 May;28(5):601-610. Epub 2022 Mar 31 doi: 10.1089/mdr.2021.0256. PMID: 35363049
Clinical Characteristics and Low Susceptibility to Daptomycin in Enterococcus faecium Bacteremia.
Namikawa H, Yamada K, Shibata W, Fujimoto H, Takizawa E, Niki M, Nakaie K, Nakamura Y, Oinuma KI, Niki M, Takemoto Y, Kaneko Y, Shuto T, Kakeya H
Tohoku J Exp Med 2017 Nov;243(3):211-218. doi: 10.1620/tjem.243.211. PMID: 29187672
Comparative Effectiveness of Cefazolin Versus Nafcillin or Oxacillin for Treatment of Methicillin-Susceptible Staphylococcus aureus Infections Complicated by Bacteremia: A Nationwide Cohort Study.
McDanel JS, Roghmann MC, Perencevich EN, Ohl ME, Goto M, Livorsi DJ, Jones M, Albertson JP, Nair R, O'Shea AMJ, Schweizer ML
Clin Infect Dis 2017 Jul 1;65(1):100-106. doi: 10.1093/cid/cix287. PMID: 28379314
Enterobacter bacteremia.
Gupta N, Aparna, Choudhary U, Garg N, Arora DR
J Assoc Physicians India 2003 Jul;51:669-72. PMID: 14621034

Diagnosis

Short versus extended treatment with a carbapenem in patients with high-risk fever of unknown origin during neutropenia: a non-inferiority, open-label, multicentre, randomised trial.
de Jonge NA, Sikkens JJ, Zweegman S, Beeker A, Ypma P, Herbers AH, Vasmel W, de Kreuk A, Coenen JLLM, Lissenberg-Witte B, Kramer MHH, van Agtmael MA, Janssen JJWM
Lancet Haematol 2022 Aug;9(8):e563-e572. Epub 2022 Jun 9 doi: 10.1016/S2352-3026(22)00145-4. PMID: 35691326
Performance of the Reveal Rapid Antibiotic Susceptibility Testing System on Gram-Negative Blood Cultures at a Large Urban Hospital.
Tibbetts R, George S, Burwell R, Rajeev L, Rhodes PA, Singh P, Samuel L
J Clin Microbiol 2022 Jun 15;60(6):e0009822. Epub 2022 May 24 doi: 10.1128/jcm.00098-22. PMID: 35607972Free PMC Article
Daptomycin.
Heidary M, Khosravi AD, Khoshnood S, Nasiri MJ, Soleimani S, Goudarzi M
J Antimicrob Chemother 2018 Jan 1;73(1):1-11. doi: 10.1093/jac/dkx349. PMID: 29059358
Randomized Trial of Rapid Multiplex Polymerase Chain Reaction-Based Blood Culture Identification and Susceptibility Testing.
Banerjee R, Teng CB, Cunningham SA, Ihde SM, Steckelberg JM, Moriarty JP, Shah ND, Mandrekar JN, Patel R
Clin Infect Dis 2015 Oct 1;61(7):1071-80. Epub 2015 Jul 20 doi: 10.1093/cid/civ447. PMID: 26197846Free PMC Article
Kingella kingae: carriage, transmission, and disease.
Yagupsky P
Clin Microbiol Rev 2015 Jan;28(1):54-79. doi: 10.1128/CMR.00028-14. PMID: 25567222Free PMC Article

Therapy

Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial.
Omrani AS, Abujarir SH, Ben Abid F, Shaar SH, Yilmaz M, Shaukat A, Alsamawi MS, Elgara MS, Alghazzawi MI, Shunnar KM, Zaqout A, Aldeeb YM, Alfouzan W, Almaslamani MA; SOAB Study Group
Clin Microbiol Infect 2024 Apr;30(4):492-498. Epub 2023 Oct 18 doi: 10.1016/j.cmi.2023.10.014. PMID: 37858867
Update on Staphylococcus aureus bacteraemia.
Tabah A, Laupland KB
Curr Opin Crit Care 2022 Oct 1;28(5):495-504. Epub 2022 Aug 4 doi: 10.1097/MCC.0000000000000974. PMID: 35942696
Short versus extended treatment with a carbapenem in patients with high-risk fever of unknown origin during neutropenia: a non-inferiority, open-label, multicentre, randomised trial.
de Jonge NA, Sikkens JJ, Zweegman S, Beeker A, Ypma P, Herbers AH, Vasmel W, de Kreuk A, Coenen JLLM, Lissenberg-Witte B, Kramer MHH, van Agtmael MA, Janssen JJWM
Lancet Haematol 2022 Aug;9(8):e563-e572. Epub 2022 Jun 9 doi: 10.1016/S2352-3026(22)00145-4. PMID: 35691326
Performance of the Reveal Rapid Antibiotic Susceptibility Testing System on Gram-Negative Blood Cultures at a Large Urban Hospital.
Tibbetts R, George S, Burwell R, Rajeev L, Rhodes PA, Singh P, Samuel L
J Clin Microbiol 2022 Jun 15;60(6):e0009822. Epub 2022 May 24 doi: 10.1128/jcm.00098-22. PMID: 35607972Free PMC Article
Randomized Trial of Rapid Multiplex Polymerase Chain Reaction-Based Blood Culture Identification and Susceptibility Testing.
Banerjee R, Teng CB, Cunningham SA, Ihde SM, Steckelberg JM, Moriarty JP, Shah ND, Mandrekar JN, Patel R
Clin Infect Dis 2015 Oct 1;61(7):1071-80. Epub 2015 Jul 20 doi: 10.1093/cid/civ447. PMID: 26197846Free PMC Article

Prognosis

Difficult-to-Treat Resistance in Gram-negative Bacteremia at 173 US Hospitals: Retrospective Cohort Analysis of Prevalence, Predictors, and Outcome of Resistance to All First-line Agents.
Kadri SS, Adjemian J, Lai YL, Spaulding AB, Ricotta E, Prevots DR, Palmore TN, Rhee C, Klompas M, Dekker JP, Powers JH 3rd, Suffredini AF, Hooper DC, Fridkin S, Danner RL; National Institutes of Health Antimicrobial Resistance Outcomes Research Initiative (NIH–ARORI)
Clin Infect Dis 2018 Nov 28;67(12):1803-1814. doi: 10.1093/cid/ciy378. PMID: 30052813Free PMC Article
Daptomycin.
Heidary M, Khosravi AD, Khoshnood S, Nasiri MJ, Soleimani S, Goudarzi M
J Antimicrob Chemother 2018 Jan 1;73(1):1-11. doi: 10.1093/jac/dkx349. PMID: 29059358
Clinical Characteristics and Low Susceptibility to Daptomycin in Enterococcus faecium Bacteremia.
Namikawa H, Yamada K, Shibata W, Fujimoto H, Takizawa E, Niki M, Nakaie K, Nakamura Y, Oinuma KI, Niki M, Takemoto Y, Kaneko Y, Shuto T, Kakeya H
Tohoku J Exp Med 2017 Nov;243(3):211-218. doi: 10.1620/tjem.243.211. PMID: 29187672
Kingella kingae: carriage, transmission, and disease.
Yagupsky P
Clin Microbiol Rev 2015 Jan;28(1):54-79. doi: 10.1128/CMR.00028-14. PMID: 25567222Free PMC Article
Enterobacter bacteremia.
Gupta N, Aparna, Choudhary U, Garg N, Arora DR
J Assoc Physicians India 2003 Jul;51:669-72. PMID: 14621034

Clinical prediction guides

Clinical and microbiological characteristics of Ruminococcus gnavus bacteremia and intra-abdominal infection.
Watanabe N, Watari T, Otsuka Y, Hosokawa N, Yamagata K, Fujioka M
Anaerobe 2024 Feb;85:102818. Epub 2024 Jan 10 doi: 10.1016/j.anaerobe.2024.102818. PMID: 38211774
Clinical outcomes and epidemiological characteristics of bacteremia in the older Japanese population.
Nakamura K, Hayakawa K, Tsuzuki S, Ide S, Nomoto H, Nakamoto T, Yamada G, Yamamoto K, Ohmagari N
J Infect Chemother 2023 Oct;29(10):971-977. Epub 2023 Jun 22 doi: 10.1016/j.jiac.2023.06.015. PMID: 37355094
Comparison of the Treatment Outcome of Piperacillin-Tazobactam versus Carbapenems for Patients with Bacteremia Caused by Extended-Spectrum β-Lactamase-Producing Escherichia coli in Areas with Low Frequency of Coproduction of OXA-1: a Preliminary Analysis.
Hoashi K, Hayama B, Suzuki M, Sakurai A, Takehana K, Enokida T, Takeda K, Ohkushi D, Doi Y, Harada S
Microbiol Spectr 2022 Aug 31;10(4):e0220622. Epub 2022 Aug 2 doi: 10.1128/spectrum.02206-22. PMID: 35916524Free PMC Article
Difficult-to-Treat Resistance in Gram-negative Bacteremia at 173 US Hospitals: Retrospective Cohort Analysis of Prevalence, Predictors, and Outcome of Resistance to All First-line Agents.
Kadri SS, Adjemian J, Lai YL, Spaulding AB, Ricotta E, Prevots DR, Palmore TN, Rhee C, Klompas M, Dekker JP, Powers JH 3rd, Suffredini AF, Hooper DC, Fridkin S, Danner RL; National Institutes of Health Antimicrobial Resistance Outcomes Research Initiative (NIH–ARORI)
Clin Infect Dis 2018 Nov 28;67(12):1803-1814. doi: 10.1093/cid/ciy378. PMID: 30052813Free PMC Article
Clinical Characteristics and Low Susceptibility to Daptomycin in Enterococcus faecium Bacteremia.
Namikawa H, Yamada K, Shibata W, Fujimoto H, Takizawa E, Niki M, Nakaie K, Nakamura Y, Oinuma KI, Niki M, Takemoto Y, Kaneko Y, Shuto T, Kakeya H
Tohoku J Exp Med 2017 Nov;243(3):211-218. doi: 10.1620/tjem.243.211. PMID: 29187672

Recent systematic reviews

Roseomonas species infections in humans: a systematic review.
Ioannou P, Mavrikaki V, Kofteridis DP
J Chemother 2020 Sep;32(5):226-236. Epub 2020 Jul 3 doi: 10.1080/1120009X.2020.1785742. PMID: 32619387
Antimicrobial Resistant Streptococcus pneumoniae: Prevalence, Mechanisms, and Clinical Implications.
Cherazard R, Epstein M, Doan TL, Salim T, Bharti S, Smith MA
Am J Ther 2017 May;24(3):e361-e369. doi: 10.1097/MJT.0000000000000551. PMID: 28430673
Antibiotic de-escalation for bloodstream infections and pneumonia: systematic review and meta-analysis.
Paul M, Dickstein Y, Raz-Pasteur A
Clin Microbiol Infect 2016 Dec;22(12):960-967. Epub 2016 Jun 6 doi: 10.1016/j.cmi.2016.05.023. PMID: 27283148
Mortality attributable to carbapenem-resistant Pseudomonas aeruginosa bacteremia: a meta-analysis of cohort studies.
Zhang Y, Chen XL, Huang AW, Liu SL, Liu WJ, Zhang N, Lu XZ
Emerg Microbes Infect 2016 Mar 23;5(3):e27. doi: 10.1038/emi.2016.22. PMID: 27004762Free PMC Article
Probiotics for preventing urinary tract infections in adults and children.
Schwenger EM, Tejani AM, Loewen PS
Cochrane Database Syst Rev 2015 Dec 23;2015(12):CD008772. doi: 10.1002/14651858.CD008772.pub2. PMID: 26695595Free PMC Article

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