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Renal artery obstruction

MedGen UID:
48406
•Concept ID:
C0035066
•
Disease or Syndrome
Synonyms: Obstruction, Renal Artery; Obstructions, Renal Artery; Renal Artery Obstruction; Renal Artery Obstructions
 
Monarch Initiative: MONDO:0006945

Definition

Narrowing or occlusion of the renal artery or arteries. It is due usually to atherosclerosis; fibromuscular dysplasia; thrombosis; embolism, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (hypertension, renovascular). [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal artery obstruction

Professional guidelines

PubMed

Endovascular Versus Medical Management of Atherosclerotic Renovascular Disease: Update and Emerging Concepts.
Pappaccogli M, Robberechts T, Lengelé JP, Van der Niepen P, Sarafidis P, Rabbia F, Persu A
Hypertension 2023 Jun;80(6):1150-1161. Epub 2023 Mar 15 doi: 10.1161/HYPERTENSIONAHA.122.17965. PMID: 36919595
Assessment and management of peripheral arterial disease: what every cardiologist should know.
Tran B
Heart 2021 Nov;107(22):1835-1843. Epub 2021 May 13 doi: 10.1136/heartjnl-2019-316164. PMID: 33985986Free PMC Article
Clinical insights into the diagnosis and management of renovascular disease. An evidence-based review.
Bloch MJ, Basile J
Minerva Med 2004 Oct;95(5):357-73. PMID: 15467512

Recent clinical studies

Etiology

Renal artery stenosis.
Safian RD
Prog Cardiovasc Dis 2021 Mar-Apr;65:60-70. Epub 2021 Mar 18 doi: 10.1016/j.pcad.2021.03.003. PMID: 33745915
Renal revascularization in resistant hypertension.
Prince M, Gupta A, Bob-Manuel T, Tafur J
Prog Cardiovasc Dis 2020 Jan-Feb;63(1):58-63. Epub 2019 Dec 7 doi: 10.1016/j.pcad.2019.12.001. PMID: 31821813
When and How Should We Revascularize Patients With Atherosclerotic Renal Artery Stenosis?
Prince M, Tafur JD, White CJ
JACC Cardiovasc Interv 2019 Mar 25;12(6):505-517. doi: 10.1016/j.jcin.2018.10.023. PMID: 30898248
Atherosclerotic Renal Artery Stenosis.
Schoepe R, McQuillan S, Valsan D, Teehan G
Adv Exp Med Biol 2017;956:209-213. doi: 10.1007/5584_2016_89. PMID: 27873231
Renal artery stenosis.
Tafur-Soto JD, White CJ
Cardiol Clin 2015 Feb;33(1):59-73. doi: 10.1016/j.ccl.2014.09.006. PMID: 25439331

Diagnosis

Transplant Renal Artery Stenosis: Current Concepts.
Gunawardena T, Sharma H
Exp Clin Transplant 2022 Dec;20(12):1049-1057. doi: 10.6002/ect.2022.0334. PMID: 36718003
Renal artery stenosis.
Safian RD
Prog Cardiovasc Dis 2021 Mar-Apr;65:60-70. Epub 2021 Mar 18 doi: 10.1016/j.pcad.2021.03.003. PMID: 33745915
Obstructive Kidney Disease.
Stevens S
Nurs Clin North Am 2018 Dec;53(4):569-578. Epub 2018 Oct 12 doi: 10.1016/j.cnur.2018.07.007. PMID: 30388982
Renal Arterial Disease and Hypertension.
Textor SC
Med Clin North Am 2017 Jan;101(1):65-79. doi: 10.1016/j.mcna.2016.08.010. PMID: 27884236Free PMC Article
Renal-artery stenosis.
Safian RD, Textor SC
N Engl J Med 2001 Feb 8;344(6):431-42. doi: 10.1056/NEJM200102083440607. PMID: 11172181

Therapy

Renal artery stenosis.
Safian RD
Prog Cardiovasc Dis 2021 Mar-Apr;65:60-70. Epub 2021 Mar 18 doi: 10.1016/j.pcad.2021.03.003. PMID: 33745915
Renal revascularization in resistant hypertension.
Prince M, Gupta A, Bob-Manuel T, Tafur J
Prog Cardiovasc Dis 2020 Jan-Feb;63(1):58-63. Epub 2019 Dec 7 doi: 10.1016/j.pcad.2019.12.001. PMID: 31821813
Endothelin: 30 Years From Discovery to Therapy.
Barton M, Yanagisawa M
Hypertension 2019 Dec;74(6):1232-1265. Epub 2019 Nov 4 doi: 10.1161/HYPERTENSIONAHA.119.12105. PMID: 31679425
When and How Should We Revascularize Patients With Atherosclerotic Renal Artery Stenosis?
Prince M, Tafur JD, White CJ
JACC Cardiovasc Interv 2019 Mar 25;12(6):505-517. doi: 10.1016/j.jcin.2018.10.023. PMID: 30898248
Renal Artery Stenosis: Optimal Therapy and Indications for Revascularization.
Patel SM, Li J, Parikh SA
Curr Cardiol Rep 2015 Sep;17(9):623. doi: 10.1007/s11886-015-0623-7. PMID: 26238738

Prognosis

Management and Outcomes of Childhood Renal Artery Stenosis and Middle Aortic Syndrome.
Rumman RK, Matsuda-Abedini M, Langlois V, Radhakrishnan S, Lorenzo AJ, Amaral J, Mertens L, Parekh RS
Am J Hypertens 2018 May 7;31(6):687-695. doi: 10.1093/ajh/hpy014. PMID: 29373648
Endovascular versus medical therapy for atherosclerotic renovascular disease.
Yu MS, Folt DA, Drummond CA, Haller ST, Cooper EL, Brewster P, Evans KL, Cooper CJ
Curr Atheroscler Rep 2014 Dec;16(12):459. doi: 10.1007/s11883-014-0459-4. PMID: 25301353Free PMC Article
Diagnosis and treatment of renal artery stenosis.
Plouin PF, Bax L
Nat Rev Nephrol 2010 Mar;6(3):151-9. Epub 2010 Jan 26 doi: 10.1038/nrneph.2009.230. PMID: 20101256
Renal artery stenosis and chronic ischemic nephropathy: epidemiology and diagnosis.
Kendrick J, Chonchol M
Adv Chronic Kidney Dis 2008 Oct;15(4):355-62. doi: 10.1053/j.ackd.2008.07.004. PMID: 18805381
Suprarenal aortic occlusion.
Tapper SS, Edwards WH, Edwards WH Jr, Mulherin JL Jr, Martin RS 3rd
J Vasc Surg 1993 Sep;18(3):372-9; discussion 379-80. doi: 10.1067/mva.1993.47466. PMID: 8377231

Clinical prediction guides

Renal Ultrasound (and Doppler Sonography) in Hypertension: An Update.
Boddi M
Adv Exp Med Biol 2017;956:191-208. doi: 10.1007/5584_2016_170. PMID: 27966109
Atherosclerotic Renal Artery Stenosis.
Schoepe R, McQuillan S, Valsan D, Teehan G
Adv Exp Med Biol 2017;956:209-213. doi: 10.1007/5584_2016_89. PMID: 27873231
Management of Renovascular Hypertension.
Smith A, Gaba RC, Bui JT, Minocha J
Tech Vasc Interv Radiol 2016 Sep;19(3):211-7. Epub 2016 Jun 3 doi: 10.1053/j.tvir.2016.06.006. PMID: 27641455
Mesenchymal stem cells and chronic renal artery stenosis.
Oliveira-Sales EB, Boim MA
Am J Physiol Renal Physiol 2016 Jan 1;310(1):F6-9. Epub 2015 Nov 4 doi: 10.1152/ajprenal.00341.2015. PMID: 26538439
Renal artery stenosis: Up-date on diagnosis and treatment.
Zeller T, Macharzina R, Rastan A, Beschorner U, Noory E
Vasa 2014 Jan;43(1):27-38. doi: 10.1024/0301-1526/a000325. PMID: 24429328

Recent systematic reviews

Endovascular Treatment of Transplant Renal Artery Stenosis: A Systematic Review and Meta-analysis.
Hinojosa-Gonzalez DE, Salgado-Garza G, Torres-Martinez M, Villegas-De Leon SU, Bueno-Gutierrez LC, Herrera-Carrillo FE, Gonzalez-Urquijo M, Segura Ibarra V, Fabiani MA, Flores-Villalba E
J Endovasc Ther 2022 Apr;29(2):294-306. Epub 2021 Aug 16 doi: 10.1177/15266028211038593. PMID: 34399594
Renal artery stent in solitary functioning kidneys: 77% of benefit: A systematic review with meta-analysis.
Ma Z, Liu L, Zhang B, Chen W, Yang J, Li H
Medicine (Baltimore) 2016 Sep;95(36):e4780. doi: 10.1097/MD.0000000000004780. PMID: 27603380Free PMC Article
Comparative Effectiveness of Management Strategies for Renal Artery Stenosis: An Updated Systematic Review.
Raman G, Adam GP, Halladay CW, Langberg VN, Azodo IA, Balk EM
Ann Intern Med 2016 Nov 1;165(9):635-649. Epub 2016 Aug 16 doi: 10.7326/M16-1053. PMID: 27536808
Efficacy of revascularization for renal artery stenosis caused by fibromuscular dysplasia: a systematic review and meta-analysis.
Trinquart L, Mounier-Vehier C, Sapoval M, Gagnon N, Plouin PF
Hypertension 2010 Sep;56(3):525-32. Epub 2010 Jul 12 doi: 10.1161/HYPERTENSIONAHA.110.152918. PMID: 20625080
Effectiveness of management strategies for renal artery stenosis: a systematic review.
Balk E, Raman G, Chung M, Ip S, Tatsioni A, Alonso A, Chew P, Gilbert SJ, Lau J
Ann Intern Med 2006 Dec 19;145(12):901-12. Epub 2006 Oct 24 doi: 10.7326/0003-4819-145-12-200612190-00143. PMID: 17062633

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