U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal atrial septum morphology

MedGen UID:
488868
•Concept ID:
C0344722
•
Congenital Abnormality
Synonym: Abnormality of the atrial septum
SNOMED CT: Abnormality of atrial septum (253363004)
 
HPO: HP:0011994

Definition

An abnormality of the interatrial septum. [from HPO]

Professional guidelines

PubMed

Management algorithm in pulmonary atresia with intact ventricular septum.
Alwi M
Catheter Cardiovasc Interv 2006 May;67(5):679-86. doi: 10.1002/ccd.20672. PMID: 16572430
Cross-sectional echocardiographic assessment of atrioventricular septal defect: basic morphology and preoperative risk factors.
Smallhorn JF
Echocardiography 2001 Jul;18(5):415-32. doi: 10.1046/j.1540-8175.2001.00415.x. PMID: 11466155
Comprehensive management of pulmonary atresia with intact ventricular septum.
Rao PS
Ann Thorac Surg 1985 Oct;40(4):409-13. doi: 10.1016/s0003-4975(10)60082-3. PMID: 3901947

Recent clinical studies

Etiology

Fetal cardiac interventions: Where do we stand?
Friedman KG, Tworetzky W
Arch Cardiovasc Dis 2020 Feb;113(2):121-128. Epub 2020 Feb 26 doi: 10.1016/j.acvd.2019.06.007. PMID: 32113817
Echocardiographic features of PFOs and paradoxical embolism: a complicated puzzle.
Aggeli C, Verveniotis A, Andrikopoulou E, Vavuranakis E, Toutouzas K, Tousoulis D
Int J Cardiovasc Imaging 2018 Dec;34(12):1849-1861. Epub 2018 Jun 28 doi: 10.1007/s10554-018-1406-1. PMID: 29956022
Porcine heart interatrial septum anatomy.
Hołda MK, Hołda J, Koziej M, Piątek K, Klimek-Piotrowska W
Ann Anat 2018 May;217:24-28. Epub 2018 Feb 16 doi: 10.1016/j.aanat.2018.01.002. PMID: 29458135
Hypertrophic cardiomyopathy.
Santos Mateo JJ, Sabater Molina M, Gimeno Blanes JR
Med Clin (Barc) 2018 Jun 8;150(11):434-442. Epub 2017 Nov 14 doi: 10.1016/j.medcli.2017.09.013. PMID: 29150126
Patent foramen ovale.
Homma S, Messé SR, Rundek T, Sun YP, Franke J, Davidson K, Sievert H, Sacco RL, Di Tullio MR
Nat Rev Dis Primers 2016 Jan 21;2:15086. doi: 10.1038/nrdp.2015.86. PMID: 27188965

Diagnosis

Hypertrophic cardiomyopathy.
Santos Mateo JJ, Sabater Molina M, Gimeno Blanes JR
Med Clin (Barc) 2018 Jun 8;150(11):434-442. Epub 2017 Nov 14 doi: 10.1016/j.medcli.2017.09.013. PMID: 29150126
Patent foramen ovale.
Homma S, Messé SR, Rundek T, Sun YP, Franke J, Davidson K, Sievert H, Sacco RL, Di Tullio MR
Nat Rev Dis Primers 2016 Jan 21;2:15086. doi: 10.1038/nrdp.2015.86. PMID: 27188965
Foetal therapy: what works? Closed interatrial septum.
Herberg U, Berg C, Geipel A, Gembruch U, Breuer J
Cardiol Young 2014 Oct;24 Suppl 2:47-54. Epub 2014 Aug 27 doi: 10.1017/S104795111400122X. PMID: 25159557
Complete atrioventricular canal.
Calabrò R, Limongelli G
Orphanet J Rare Dis 2006 Apr 5;1:8. doi: 10.1186/1750-1172-1-8. PMID: 16722604Free PMC Article
Hypertrophic cardiomyopathy.
Sasson Z, Rakowski H, Wigle ED
Cardiol Clin 1988 May;6(2):233-88. PMID: 3066484

Therapy

The Secrets of the Frogs Heart.
Corno AF, Zhou Z, Uppu SC, Huang S, Marino B, Milewicz DM, Salazar JD
Pediatr Cardiol 2022 Oct;43(7):1471-1480. Epub 2022 Mar 15 doi: 10.1007/s00246-022-02870-8. PMID: 35290490
Patent foramen ovale closure for secondary prevention of cryptogenic stroke.
Kolte D, Palacios IF
Expert Rev Cardiovasc Ther 2021 Mar;19(3):211-220. Epub 2021 Feb 19 doi: 10.1080/14779072.2021.1878026. PMID: 33605829
Fetal cardiac interventions: Where do we stand?
Friedman KG, Tworetzky W
Arch Cardiovasc Dis 2020 Feb;113(2):121-128. Epub 2020 Feb 26 doi: 10.1016/j.acvd.2019.06.007. PMID: 32113817
Hypertrophic cardiomyopathy.
Santos Mateo JJ, Sabater Molina M, Gimeno Blanes JR
Med Clin (Barc) 2018 Jun 8;150(11):434-442. Epub 2017 Nov 14 doi: 10.1016/j.medcli.2017.09.013. PMID: 29150126
Patent foramen ovale.
Dattilo PB, Kim MS, Carroll JD
Cardiol Clin 2013 Aug;31(3):401-15. doi: 10.1016/j.ccl.2013.05.002. PMID: 23931102

Prognosis

Echocardiographic features of PFOs and paradoxical embolism: a complicated puzzle.
Aggeli C, Verveniotis A, Andrikopoulou E, Vavuranakis E, Toutouzas K, Tousoulis D
Int J Cardiovasc Imaging 2018 Dec;34(12):1849-1861. Epub 2018 Jun 28 doi: 10.1007/s10554-018-1406-1. PMID: 29956022
Foetal therapy: what works? Closed interatrial septum.
Herberg U, Berg C, Geipel A, Gembruch U, Breuer J
Cardiol Young 2014 Oct;24 Suppl 2:47-54. Epub 2014 Aug 27 doi: 10.1017/S104795111400122X. PMID: 25159557
Cat eye syndrome.
Sharma D, Murki S, Pratap T, Vasikarla M
BMJ Case Rep 2014 May 19;2014 doi: 10.1136/bcr-2014-203923. PMID: 24842361Free PMC Article
Complete atrioventricular canal.
Calabrò R, Limongelli G
Orphanet J Rare Dis 2006 Apr 5;1:8. doi: 10.1186/1750-1172-1-8. PMID: 16722604Free PMC Article
The surgical anatomy of the conduction tissues.
Anderson RH, Ho SY, Becker AE
Thorax 1983 Jun;38(6):408-20. doi: 10.1136/thx.38.6.408. PMID: 6348996Free PMC Article

Clinical prediction guides

Patent foramen ovale closure for secondary prevention of cryptogenic stroke.
Kolte D, Palacios IF
Expert Rev Cardiovasc Ther 2021 Mar;19(3):211-220. Epub 2021 Feb 19 doi: 10.1080/14779072.2021.1878026. PMID: 33605829
Echocardiographic features of PFOs and paradoxical embolism: a complicated puzzle.
Aggeli C, Verveniotis A, Andrikopoulou E, Vavuranakis E, Toutouzas K, Tousoulis D
Int J Cardiovasc Imaging 2018 Dec;34(12):1849-1861. Epub 2018 Jun 28 doi: 10.1007/s10554-018-1406-1. PMID: 29956022
Porcine heart interatrial septum anatomy.
Hołda MK, Hołda J, Koziej M, Piątek K, Klimek-Piotrowska W
Ann Anat 2018 May;217:24-28. Epub 2018 Feb 16 doi: 10.1016/j.aanat.2018.01.002. PMID: 29458135
Atrial septal pouch - Morphological features and clinical considerations.
Hołda MK, Koziej M, Hołda J, Piątek K, Tyrak K, Chołopiak W, Bolechała F, Walocha JA, Klimek-Piotrowska W
Int J Cardiol 2016 Oct 1;220:337-42. Epub 2016 Jun 28 doi: 10.1016/j.ijcard.2016.06.141. PMID: 27390952
The surgical anatomy of the conduction tissues.
Anderson RH, Ho SY, Becker AE
Thorax 1983 Jun;38(6):408-20. doi: 10.1136/thx.38.6.408. PMID: 6348996Free PMC Article

Recent systematic reviews

Morphometric Features of Patent Foramen Ovale as a Risk Factor of Cerebrovascular Accidents: A Systematic Review and Meta-Analysis.
Hołda MK, Koziej M
Cerebrovasc Dis 2020;49(1):1-9. Epub 2020 Feb 25 doi: 10.1159/000506433. PMID: 32097931

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...