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Decreased erythrocyte sedimentation rate

MedGen UID:
508793
•Concept ID:
C0151631
•
Finding
Synonyms: Decreased ESR; Erythrocyte sedimentation rate (ESR) low; Erythrocyte sedimentation rate below reference range; ESR low; Low erythrocyte sedimentation rate; Low ESR
SNOMED CT: ESR low (165466008); Erythrocyte sedimentation rate (ESR) low (165466008); Low erythrocyte sedimentation rate (165466008); Erythrocyte sedimentation rate below reference range (165466008)
 
HPO: HP:0025022

Definition

A reduced erythrocyte sedimentation rate (ESR). The ESR is a test that measures the distance that erythrocytes have fallen after one hour in a vertical column of anticoagulated blood under the influence of gravity. The ESR is a nonspecific finding. A decreased ESR may be seen in polycythemia or in certain blood diseases in which red blood cells have an irregular or smaller shape that causes slower settling. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased erythrocyte sedimentation rate

Professional guidelines

PubMed

Variation in the Management of Hospitalized Children With Orbital Cellulitis Over 10 Years.
Nguyen EL, Hersi L, Mahant S, Cichon J, Drouin O, Pound C, Quet J, Wahi G, Bayliss A, Vomiero G, Foulds JL, Kanani R, Sakran M, Sehgal A, Borkhoff CM, Pullenayegum E, Widjaja E, Reginald A, Wolter NE, Oni S, Anwar R, Louriachi H, Ge Y, Kirolos N, Patel A, Jasani H, Kornelsen E, Chugh A, Gouda S, Akbaroghli S, McKerlie M, Parkin PC, Gill PJ
Hosp Pediatr 2023 May 1;13(5):375-391. doi: 10.1542/hpeds.2022-007006. PMID: 37122049
Differential diagnosis of increased Erythrocyte Sedimentation rate.
Ščudla V, Horák P
Vnitr Lek 2023 Winter;69(1):48-56. doi: 10.36290/vnl.2023.007. PMID: 36931882
Systemic inflammation and its response to treatment in patients with asthma.
Girdhar A, Kumar V, Singh A, Menon B, Vijayan VK
Respir Care 2011 Jun;56(6):800-5. doi: 10.4187/respcare.00601. PMID: 21679494

Recent clinical studies

Etiology

Efficacy and safety of iguratimod combined with methylprednisolone for primary Sjögren's syndrome: a meta-analysis and trial sequential analysis.
Hu G, Yu YF, Yin S, Yang XY, Xu Q, You H
Eur Rev Med Pharmacol Sci 2023 Aug;27(16):7544-7556. doi: 10.26355/eurrev_202308_33406. PMID: 37667931
Differences between Risk Factors for Sepsis and Septic Shock in Obstructive Urolithiasis.
Lee SH, Choi T, Choi J, Yoo KH
J Korean Med Sci 2020 Nov 9;35(43):e359. doi: 10.3346/jkms.2020.35.e359. PMID: 33169555Free PMC Article
Adjunct immune therapy of first-diagnosed TB, relapsed TB, treatment-failed TB, multidrug-resistant TB and TB/HIV.
Butov DA, Efremenko YV, Prihoda ND, Yurchenko LI, Sokolenko NI, Arjanova OV, Stepanenko AL, Butova TS, Zaitzeva SS, Jirathitikal V, Bourinbaiar AS, Kutsyna GA
Immunotherapy 2012 Jul;4(7):687-95. doi: 10.2217/imt.12.59. PMID: 22853755
Clinical analysis of macrophage activation syndrome in pediatric patients with autoimmune diseases.
Lin CI, Yu HH, Lee JH, Wang LC, Lin YT, Yang YH, Chiang BL
Clin Rheumatol 2012 Aug;31(8):1223-30. Epub 2012 May 22 doi: 10.1007/s10067-012-1998-0. PMID: 22615046
Treatment of primary Sjögren's syndrome with hydroxychloroquine.
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Am J Med 1988 Oct 14;85(4A):62-7. doi: 10.1016/0002-9343(88)90365-8. PMID: 3177432

Diagnosis

Differential diagnosis of increased Erythrocyte Sedimentation rate.
Ščudla V, Horák P
Vnitr Lek 2023 Winter;69(1):48-56. doi: 10.36290/vnl.2023.007. PMID: 36931882
Differences between Risk Factors for Sepsis and Septic Shock in Obstructive Urolithiasis.
Lee SH, Choi T, Choi J, Yoo KH
J Korean Med Sci 2020 Nov 9;35(43):e359. doi: 10.3346/jkms.2020.35.e359. PMID: 33169555Free PMC Article
Adjunct immune therapy of first-diagnosed TB, relapsed TB, treatment-failed TB, multidrug-resistant TB and TB/HIV.
Butov DA, Efremenko YV, Prihoda ND, Yurchenko LI, Sokolenko NI, Arjanova OV, Stepanenko AL, Butova TS, Zaitzeva SS, Jirathitikal V, Bourinbaiar AS, Kutsyna GA
Immunotherapy 2012 Jul;4(7):687-95. doi: 10.2217/imt.12.59. PMID: 22853755
Clinical analysis of macrophage activation syndrome in pediatric patients with autoimmune diseases.
Lin CI, Yu HH, Lee JH, Wang LC, Lin YT, Yang YH, Chiang BL
Clin Rheumatol 2012 Aug;31(8):1223-30. Epub 2012 May 22 doi: 10.1007/s10067-012-1998-0. PMID: 22615046

Therapy

Efficacy and safety of iguratimod combined with methylprednisolone for primary Sjögren's syndrome: a meta-analysis and trial sequential analysis.
Hu G, Yu YF, Yin S, Yang XY, Xu Q, You H
Eur Rev Med Pharmacol Sci 2023 Aug;27(16):7544-7556. doi: 10.26355/eurrev_202308_33406. PMID: 37667931
The Role of Multimodality Imaging in Monitoring Disease Activity and Therapeutic Response to Tocilizumab in Giant Cell Arteritis.
Conticini E, Sota J, Falsetti P, Baldi C, Bardelli M, Bellisai F, Tosi GM, Frediani B, Cantarini L
Mediators Inflamm 2020;2020:3203241. Epub 2020 Sep 27 doi: 10.1155/2020/3203241. PMID: 33061825Free PMC Article
Adjunct immune therapy of first-diagnosed TB, relapsed TB, treatment-failed TB, multidrug-resistant TB and TB/HIV.
Butov DA, Efremenko YV, Prihoda ND, Yurchenko LI, Sokolenko NI, Arjanova OV, Stepanenko AL, Butova TS, Zaitzeva SS, Jirathitikal V, Bourinbaiar AS, Kutsyna GA
Immunotherapy 2012 Jul;4(7):687-95. doi: 10.2217/imt.12.59. PMID: 22853755
Clinical analysis of macrophage activation syndrome in pediatric patients with autoimmune diseases.
Lin CI, Yu HH, Lee JH, Wang LC, Lin YT, Yang YH, Chiang BL
Clin Rheumatol 2012 Aug;31(8):1223-30. Epub 2012 May 22 doi: 10.1007/s10067-012-1998-0. PMID: 22615046
Treatment of primary Sjögren's syndrome with hydroxychloroquine.
Fox RI, Chan E, Benton L, Fong S, Friedlaender M, Howell FV
Am J Med 1988 Oct 14;85(4A):62-7. doi: 10.1016/0002-9343(88)90365-8. PMID: 3177432

Prognosis

Differences between Risk Factors for Sepsis and Septic Shock in Obstructive Urolithiasis.
Lee SH, Choi T, Choi J, Yoo KH
J Korean Med Sci 2020 Nov 9;35(43):e359. doi: 10.3346/jkms.2020.35.e359. PMID: 33169555Free PMC Article
A controlled trial comparing sulfasalazine, gold sodium thiomalate, and placebo in rheumatoid arthritis.
Williams HJ, Ward JR, Dahl SL, Clegg DO, Willkens RF, Oglesby T, Weisman MH, Schlegel S, Michaels RM, Luggen ME
Arthritis Rheum 1988 Jun;31(6):702-13. doi: 10.1002/art.1780310602. PMID: 2898244

Clinical prediction guides

Efficacy and safety of iguratimod combined with methylprednisolone for primary Sjögren's syndrome: a meta-analysis and trial sequential analysis.
Hu G, Yu YF, Yin S, Yang XY, Xu Q, You H
Eur Rev Med Pharmacol Sci 2023 Aug;27(16):7544-7556. doi: 10.26355/eurrev_202308_33406. PMID: 37667931
Differences between Risk Factors for Sepsis and Septic Shock in Obstructive Urolithiasis.
Lee SH, Choi T, Choi J, Yoo KH
J Korean Med Sci 2020 Nov 9;35(43):e359. doi: 10.3346/jkms.2020.35.e359. PMID: 33169555Free PMC Article
The Role of Multimodality Imaging in Monitoring Disease Activity and Therapeutic Response to Tocilizumab in Giant Cell Arteritis.
Conticini E, Sota J, Falsetti P, Baldi C, Bardelli M, Bellisai F, Tosi GM, Frediani B, Cantarini L
Mediators Inflamm 2020;2020:3203241. Epub 2020 Sep 27 doi: 10.1155/2020/3203241. PMID: 33061825Free PMC Article
Adjunct immune therapy of first-diagnosed TB, relapsed TB, treatment-failed TB, multidrug-resistant TB and TB/HIV.
Butov DA, Efremenko YV, Prihoda ND, Yurchenko LI, Sokolenko NI, Arjanova OV, Stepanenko AL, Butova TS, Zaitzeva SS, Jirathitikal V, Bourinbaiar AS, Kutsyna GA
Immunotherapy 2012 Jul;4(7):687-95. doi: 10.2217/imt.12.59. PMID: 22853755
Treatment of primary Sjögren's syndrome with hydroxychloroquine.
Fox RI, Chan E, Benton L, Fong S, Friedlaender M, Howell FV
Am J Med 1988 Oct 14;85(4A):62-7. doi: 10.1016/0002-9343(88)90365-8. PMID: 3177432

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