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Thrombotic stroke

MedGen UID:
537131
Concept ID:
C0242129
Disease or Syndrome
Synonyms: Stroke, Thrombotic; Thrombotic Stroke; Thrombotic Strokes
SNOMED CT: Thrombotic stroke (371040005)

Definition

A type of ischemic stroke resulting from obstruction due to a BLOOD CLOT formed within in a CEREBRAL ARTERY often associated with ATHEROSCLEROSIS. A stroke due to a blood clot in a cerebral vein is a venous infarction (see VENOUS INFARCTION, BRAIN). [from MeSH]

Professional guidelines

PubMed

Le VT, Abdi HH, Sánchez PJ, Yossef L, Reagan PB, Slaughter LA, Firestine A, Slaughter JL
Am J Perinatol 2021 Apr;38(5):469-476. Epub 2019 Oct 10 doi: 10.1055/s-0039-1698457. PMID: 31600794Free PMC Article
Panichpisal K, Rozner E, Levine SR
Curr Rheumatol Rep 2012 Feb;14(1):99-106. doi: 10.1007/s11926-011-0223-5. PMID: 22109663
Chroni E, Monastirli A, Tsambaos D
Drug Saf 2010 Jan 1;33(1):25-34. doi: 10.2165/11319020-000000000-00000. PMID: 20000864

Curated

UK NICE Guideline (NG236), Stroke rehabilitation in adults, 2023

UK NICE Guideline NG128, Stroke and transient ischaemic attack in over 16s: diagnosis and initial management, 2019

Recent clinical studies

Etiology

Ahmad SJ, Feigen CM, Vazquez JP, Kobets AJ, Altschul DJ
J Integr Neurosci 2022 Apr 6;21(3):77. doi: 10.31083/j.jin2103077. PMID: 35633158
Jovin TG, Nogueira RG, Lansberg MG, Demchuk AM, Martins SO, Mocco J, Ribo M, Jadhav AP, Ortega-Gutierrez S, Hill MD, Lima FO, Haussen DC, Brown S, Goyal M, Siddiqui AH, Heit JJ, Menon BK, Kemp S, Budzik R, Urra X, Marks MP, Costalat V, Liebeskind DS, Albers GW
Lancet 2022 Jan 15;399(10321):249-258. Epub 2021 Nov 11 doi: 10.1016/S0140-6736(21)01341-6. PMID: 34774198
Theophanous R, Huang W, Ragsdale L
Emerg Med Clin North Am 2021 May;39(2):323-338. doi: 10.1016/j.emc.2021.01.010. PMID: 33863462
Vlisides P, Mashour GA
Can J Anaesth 2016 Feb;63(2):193-204. Epub 2015 Sep 21 doi: 10.1007/s12630-015-0494-9. PMID: 26391795Free PMC Article
Doyle AE
Am J Hypertens 1991 Feb;4(2 Pt 2):103S-106S. doi: 10.1093/ajh/4.2.103s. PMID: 2021454

Diagnosis

Lun R, Cerasuolo JO, Carrier M, Gross PL, Kapral MK, Shamy M, Dowlatshahi D, Sutradhar R, Siegal DM
Stroke 2023 Dec;54(12):3064-3073. Epub 2023 Oct 18 doi: 10.1161/STROKEAHA.123.042993. PMID: 37850360
Kitazono T, Kamouchi M, Matsumaru Y, Shirai T, Takita A, Kuroda T, Kimura K
Cerebrovasc Dis 2023;52(6):720-729. Epub 2023 Apr 3 doi: 10.1159/000529149. PMID: 37011599
Theophanous R, Huang W, Ragsdale L
Emerg Med Clin North Am 2021 May;39(2):323-338. doi: 10.1016/j.emc.2021.01.010. PMID: 33863462
Khan A , Shin MS , Jee SH , Park YH
Analyst 2020 Mar 7;145(5):1695-1705. Epub 2020 Jan 2 doi: 10.1039/c9an02032b. PMID: 31895365
Pretorius E, Kell DB
Integr Biol (Camb) 2014 May;6(5):486-510. doi: 10.1039/c4ib00025k. PMID: 24714688

Therapy

Jovin TG, Nogueira RG, Lansberg MG, Demchuk AM, Martins SO, Mocco J, Ribo M, Jadhav AP, Ortega-Gutierrez S, Hill MD, Lima FO, Haussen DC, Brown S, Goyal M, Siddiqui AH, Heit JJ, Menon BK, Kemp S, Budzik R, Urra X, Marks MP, Costalat V, Liebeskind DS, Albers GW
Lancet 2022 Jan 15;399(10321):249-258. Epub 2021 Nov 11 doi: 10.1016/S0140-6736(21)01341-6. PMID: 34774198
Feske SK
Am J Med 2021 Dec;134(12):1457-1464. Epub 2021 Aug 27 doi: 10.1016/j.amjmed.2021.07.027. PMID: 34454905
Theophanous R, Huang W, Ragsdale L
Emerg Med Clin North Am 2021 May;39(2):323-338. doi: 10.1016/j.emc.2021.01.010. PMID: 33863462
Vlisides P, Mashour GA
Can J Anaesth 2016 Feb;63(2):193-204. Epub 2015 Sep 21 doi: 10.1007/s12630-015-0494-9. PMID: 26391795Free PMC Article
Panichpisal K, Rozner E, Levine SR
Curr Rheumatol Rep 2012 Feb;14(1):99-106. doi: 10.1007/s11926-011-0223-5. PMID: 22109663

Prognosis

Lun R, Cerasuolo JO, Carrier M, Gross PL, Kapral MK, Shamy M, Dowlatshahi D, Sutradhar R, Siegal DM
Stroke 2023 Dec;54(12):3064-3073. Epub 2023 Oct 18 doi: 10.1161/STROKEAHA.123.042993. PMID: 37850360
Khan A , Shin MS , Jee SH , Park YH
Analyst 2020 Mar 7;145(5):1695-1705. Epub 2020 Jan 2 doi: 10.1039/c9an02032b. PMID: 31895365
Selvan P, Piran P, Balucani C, Tark B, Adler Z, Levine SR
J Stroke Cerebrovasc Dis 2017 Mar;26(3):608-617. Epub 2016 Dec 29 doi: 10.1016/j.jstrokecerebrovasdis.2016.11.111. PMID: 28041897
Lidegaard Ø, Løkkegaard E, Jensen A, Skovlund CW, Keiding N
N Engl J Med 2012 Jun 14;366(24):2257-66. doi: 10.1056/NEJMoa1111840. PMID: 22693997
Milionis HJ, Winder AF, Mikhailidis DP
J Clin Pathol 2000 Jul;53(7):487-96. doi: 10.1136/jcp.53.7.487. PMID: 10961170Free PMC Article

Clinical prediction guides

Kitazono T, Kamouchi M, Matsumaru Y, Nakamura M, Umemura K, Matsuo H, Koyama N, Tsutsumi J, Kimura K
J Atheroscler Thromb 2023 Mar 1;30(3):222-236. Epub 2022 May 21 doi: 10.5551/jat.63473. PMID: 35599000Free PMC Article
Jovin TG, Nogueira RG, Lansberg MG, Demchuk AM, Martins SO, Mocco J, Ribo M, Jadhav AP, Ortega-Gutierrez S, Hill MD, Lima FO, Haussen DC, Brown S, Goyal M, Siddiqui AH, Heit JJ, Menon BK, Kemp S, Budzik R, Urra X, Marks MP, Costalat V, Liebeskind DS, Albers GW
Lancet 2022 Jan 15;399(10321):249-258. Epub 2021 Nov 11 doi: 10.1016/S0140-6736(21)01341-6. PMID: 34774198
Griñán K, Arboix A, Massons J, Díez L, Vergés E, Gil F, Arboix-Alió J, Sánchez-López MJ, García-Eroles L
Rev Invest Clin 2020 May 7;73(1):023-030. doi: 10.24875/RIC.20000227. PMID: 33053576
Betteridge DJ, Carmena R
Nat Rev Endocrinol 2016 Feb;12(2):99-110. Epub 2015 Dec 15 doi: 10.1038/nrendo.2015.194. PMID: 26668119
Milionis HJ, Winder AF, Mikhailidis DP
J Clin Pathol 2000 Jul;53(7):487-96. doi: 10.1136/jcp.53.7.487. PMID: 10961170Free PMC Article

Recent systematic reviews

Jovin TG, Nogueira RG, Lansberg MG, Demchuk AM, Martins SO, Mocco J, Ribo M, Jadhav AP, Ortega-Gutierrez S, Hill MD, Lima FO, Haussen DC, Brown S, Goyal M, Siddiqui AH, Heit JJ, Menon BK, Kemp S, Budzik R, Urra X, Marks MP, Costalat V, Liebeskind DS, Albers GW
Lancet 2022 Jan 15;399(10321):249-258. Epub 2021 Nov 11 doi: 10.1016/S0140-6736(21)01341-6. PMID: 34774198
Oliveira M, Fidalgo M, Fontão L, Antão J, Marques S, Afreixo V, Gregório T
Am J Emerg Med 2021 Apr;42:31-37. Epub 2020 Dec 24 doi: 10.1016/j.ajem.2020.12.026. PMID: 33440328
He W, Chu Y
Sci Rep 2017 Jun 13;7(1):3360. doi: 10.1038/s41598-017-03653-5. PMID: 28611377Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE Guideline (NG236), Stroke rehabilitation in adults, 2023
    • NICE, 2019
      UK NICE Guideline NG128, Stroke and transient ischaemic attack in over 16s: diagnosis and initial management, 2019

    Consumer resources

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