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Meconium peritonitis

MedGen UID:
542628
•Concept ID:
C0270250
•
Disease or Syndrome
Synonym: Meconium Peritonitis
SNOMED CT: Meconium peritonitis (57341009)
 
HPO: HP:0030717

Definition

Peritonitis caused by intrauterine intestinal rupture and spillage of fetal meconium into the fetal peritoneal cavity. Intra-peritoneal meconium usually calcifies, sometimes within 24 hours. Ultrasound findings may include intraabdominal calcifications. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMeconium peritonitis

Conditions with this feature

Meier-Gorlin syndrome 7
MedGen UID:
934705
•Concept ID:
C4310738
•
Disease or Syndrome
Any Meier-Gorlin syndrome in which the cause of the disease is a mutation in the CDC45 gene.
See: Condition Record
Meier-Gorlin syndrome 7

Professional guidelines

PubMed

Analysis of the clinical diagnosis and treatment of fetal meconium peritonitis.
Zheng XQ, Wu DM, Chen X, Lin JX, Wang XC, Ren KH, Liu HQ, Xu RL, Yan JY
J Matern Fetal Neonatal Med 2024 Dec;37(1):2250045. Epub 2024 Feb 25 doi: 10.1080/14767058.2023.2250045. PMID: 38403928
Postnatal Treatment in Antenatally Diagnosed Meconium Peritonitis.
Ionescu S, Andrei B, Oancea M, Licsandru E, Ivanov M, Marcu V, Popa-Stanila R, Mocanu M
Chirurgia (Bucur) 2015 Nov-Dec;110(6):538-44. PMID: 26713828
Contemporary management of meconium ileus.
Rescorla FJ, Grosfeld JL
World J Surg 1993 May-Jun;17(3):318-25. doi: 10.1007/BF01658698. PMID: 8337877

Recent clinical studies

Etiology

Fetal Meconium Peritonitis: A Clinical Study of Nine Cases.
Fu F, Song X, Huang F, Yuan H, Xiao L
Comput Intell Neurosci 2022;2022:8658999. Epub 2022 May 27 doi: 10.1155/2022/8658999. PMID: 35669660Free PMC Article
Gastrointestinal Emergency in Neonates and Infants: A Pictorial Essay.
Choi G, Je BK, Kim YJ
Korean J Radiol 2022 Jan;23(1):124-138. doi: 10.3348/kjr.2021.0111. PMID: 34983099Free PMC Article
Meconium peritonitis: A 22-year review in a tertiary referral center.
Wong CWY, Wong KKY
J Pediatr Surg 2022 Aug;57(8):1504-1508. Epub 2021 Oct 15 doi: 10.1016/j.jpedsurg.2021.10.006. PMID: 34794810
Fetal Meconium Peritonitis - Prenatal Findings and Postnatal Outcome: A Case Series, Systematic Review, and Meta-Analysis.
Shinar S, Agrawal S, Ryu M, Van Mieghem T, Daneman A, Ryan G, Zani A, Chiu P, Chitayat D
Ultraschall Med 2022 Apr;43(2):194-203. Epub 2020 Jun 23 doi: 10.1055/a-1194-4363. PMID: 32575129
Meconium peritonitis.
Niramis R, Watanatittan S, Anuntakosol M, Rattanasuwan T, Buranakitjaroen V
J Med Assoc Thai 1999 Nov;82(11):1063-70. PMID: 10659538

Diagnosis

Gastrointestinal Emergency in Neonates and Infants: A Pictorial Essay.
Choi G, Je BK, Kim YJ
Korean J Radiol 2022 Jan;23(1):124-138. doi: 10.3348/kjr.2021.0111. PMID: 34983099Free PMC Article
Meconium peritonitis: A 22-year review in a tertiary referral center.
Wong CWY, Wong KKY
J Pediatr Surg 2022 Aug;57(8):1504-1508. Epub 2021 Oct 15 doi: 10.1016/j.jpedsurg.2021.10.006. PMID: 34794810
Meconium ileus in Cystic Fibrosis.
Sathe M, Houwen R
J Cyst Fibros 2017 Nov;16 Suppl 2:S32-S39. doi: 10.1016/j.jcf.2017.06.007. PMID: 28986020
Pediatric scrotal ultrasound: review and update.
Alkhori NA, Barth RA
Pediatr Radiol 2017 Aug;47(9):1125-1133. Epub 2017 Aug 4 doi: 10.1007/s00247-017-3923-9. PMID: 28779199
Intestinal atresia.
Prasad TR, Bajpai M
Indian J Pediatr 2000 Sep;67(9):671-8. doi: 10.1007/BF02762182. PMID: 11028122

Therapy

Fetal Meconium Peritonitis - Prenatal Findings and Postnatal Outcome: A Case Series, Systematic Review, and Meta-Analysis.
Shinar S, Agrawal S, Ryu M, Van Mieghem T, Daneman A, Ryan G, Zani A, Chiu P, Chitayat D
Ultraschall Med 2022 Apr;43(2):194-203. Epub 2020 Jun 23 doi: 10.1055/a-1194-4363. PMID: 32575129
Is the Bishop-Koop procedure useful in severe jejunoileal atresia?
Peng Y, Zheng H, He Q, Wang Z, Zhang H, Chaudhari PB, Zhong W, Yu J
J Pediatr Surg 2018 Oct;53(10):1914-1917. Epub 2018 Apr 5 doi: 10.1016/j.jpedsurg.2018.03.027. PMID: 29709288
Meconium Peritonitis: Correlation of Antenatal Diagnosis and Postnatal Outcome - An Institutional Experience over 10 Years.
Ping LM, Rajadurai VS, Saffari SE, Chandran S
Fetal Diagn Ther 2017;42(1):57-62. Epub 2016 Sep 21 doi: 10.1159/000449380. PMID: 27649500
Fetal Meconium Peritonitis and Maternal Liver Disease.
Lai CWS, Shek NWM
Obstet Gynecol 2016 Apr;127(4):740-743. doi: 10.1097/AOG.0000000000001337. PMID: 26959203
Gastrointestinal surgery in cystic fibrosis.
Beierle EA, Vinocur CD
Curr Opin Pulm Med 1998 Nov;4(6):319-25. doi: 10.1097/00063198-199811000-00002. PMID: 10813209

Prognosis

Meconium peritonitis: A 22-year review in a tertiary referral center.
Wong CWY, Wong KKY
J Pediatr Surg 2022 Aug;57(8):1504-1508. Epub 2021 Oct 15 doi: 10.1016/j.jpedsurg.2021.10.006. PMID: 34794810
Fetal Meconium Peritonitis - Prenatal Findings and Postnatal Outcome: A Case Series, Systematic Review, and Meta-Analysis.
Shinar S, Agrawal S, Ryu M, Van Mieghem T, Daneman A, Ryan G, Zani A, Chiu P, Chitayat D
Ultraschall Med 2022 Apr;43(2):194-203. Epub 2020 Jun 23 doi: 10.1055/a-1194-4363. PMID: 32575129
Intra-uterine Meconium Peritonitis.
Nawaz R, Khushdil A, Ahmed N
J Coll Physicians Surg Pak 2019 Jan;29(1):97-98. doi: 10.29271/jcpsp.2019.01.97. PMID: 30630586
Intestinal atresia.
Prasad TR, Bajpai M
Indian J Pediatr 2000 Sep;67(9):671-8. doi: 10.1007/BF02762182. PMID: 11028122
Meconium peritonitis.
Niramis R, Watanatittan S, Anuntakosol M, Rattanasuwan T, Buranakitjaroen V
J Med Assoc Thai 1999 Nov;82(11):1063-70. PMID: 10659538

Clinical prediction guides

Fetal Meconium Peritonitis - Prenatal Findings and Postnatal Outcome: A Case Series, Systematic Review, and Meta-Analysis.
Shinar S, Agrawal S, Ryu M, Van Mieghem T, Daneman A, Ryan G, Zani A, Chiu P, Chitayat D
Ultraschall Med 2022 Apr;43(2):194-203. Epub 2020 Jun 23 doi: 10.1055/a-1194-4363. PMID: 32575129
Meconium peritonitis: the role of postnatal radiographic and sonographic findings in predicting the need for surgery.
Caro-Domínguez P, Zani A, Chitayat D, Daneman A
Pediatr Radiol 2018 Nov;48(12):1755-1762. Epub 2018 Jul 16 doi: 10.1007/s00247-018-4198-5. PMID: 30014199
Meconium Peritonitis: Correlation of Antenatal Diagnosis and Postnatal Outcome - An Institutional Experience over 10 Years.
Ping LM, Rajadurai VS, Saffari SE, Chandran S
Fetal Diagn Ther 2017;42(1):57-62. Epub 2016 Sep 21 doi: 10.1159/000449380. PMID: 27649500
Intestinal atresia.
Prasad TR, Bajpai M
Indian J Pediatr 2000 Sep;67(9):671-8. doi: 10.1007/BF02762182. PMID: 11028122
Fetal gastric pseudomasses.
Fakhry J, Shapiro LR, Schechter A, Weingarten M, Glennon A
J Ultrasound Med 1987 Apr;6(4):177-80. doi: 10.7863/jum.1987.6.4.177. PMID: 3295283

Recent systematic reviews

Fetal Meconium Peritonitis - Prenatal Findings and Postnatal Outcome: A Case Series, Systematic Review, and Meta-Analysis.
Shinar S, Agrawal S, Ryu M, Van Mieghem T, Daneman A, Ryan G, Zani A, Chiu P, Chitayat D
Ultraschall Med 2022 Apr;43(2):194-203. Epub 2020 Jun 23 doi: 10.1055/a-1194-4363. PMID: 32575129

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