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Dissociated vertical deviation

MedGen UID:
573279
•Concept ID:
C0339640
•
Disease or Syndrome
Synonyms: Dissociated Vertical Deviation; Dissociated Vertical Deviations
SNOMED CT: Dissociated vertical deviation (232108003); DVD - Dissociated vertical deviation (232108003); DVD - Dissociated vertical divergence (232108003); Alternating sursumduction (232108003); Dissociated vertical divergence (232108003)
 
HPO: HP:0500074

Definition

An incomitant tendency for an occluded eye to elevate and extort which resolves on uncovering. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDissociated vertical deviation

Professional guidelines

PubMed

Conventional surgery versus botulinum toxin injection for the management of esotropia in children with Down syndrome.
Alnajjar T, Sesma G, Alfreihi S
J AAPOS 2022 Oct;26(5):251.e1-251.e4. Epub 2022 Sep 15 doi: 10.1016/j.jaapos.2022.06.001. PMID: 36116586
Diagnosis and surgical treatment of dissociated horizontal deviation strabismus.
Gamio S
Binocul Vis Strabolog Q Simms Romano 2011;26(1):43-50. PMID: 21438856
Botulinum treatment of infantile esotropia with abduction nystagmus.
Ruiz MF, Moreno M, Sánchez-Garrido CM, Rodríguez JM
J Pediatr Ophthalmol Strabismus 2000 Jul-Aug;37(4):196-205. doi: 10.3928/0191-3913-20000701-05. PMID: 10955541

Recent clinical studies

Etiology

Interventions for infantile esotropia.
Mehner L, Ng SM, Singh J
Cochrane Database Syst Rev 2023 Jan 16;1(1):CD004917. doi: 10.1002/14651858.CD004917.pub4. PMID: 36645238Free PMC Article
Surgical management of Helveston syndrome (Triad exotropia).
Jin X, Peng Y, Al-Wesabi SA, Deng J, Ming Y, Wu X
Int Ophthalmol 2022 Apr;42(4):1021-1030. Epub 2021 Nov 8 doi: 10.1007/s10792-021-02027-1. PMID: 34748142Free PMC Article
Different Surgical Approaches for Treatment of Dissociated Vertical Deviation (DVD).
Mravicic I, Gulic MP, Barisic A, Biscevic A, Pjano MA, Pidro A
Med Arch 2019 Dec;73(6):386-390. doi: 10.5455/medarh.2019.73.386-390. PMID: 32082005Free PMC Article
Interventions for dissociated vertical deviation.
Hatt SR, Wang X, Holmes JM
Cochrane Database Syst Rev 2015 Nov 20;2015(11):CD010868. doi: 10.1002/14651858.CD010868.pub2. PMID: 26587695Free PMC Article
Comitant strabismus.
Schworm HD, Rudolph G
Curr Opin Ophthalmol 2000 Oct;11(5):310-7. doi: 10.1097/00055735-200010000-00004. PMID: 11148695

Diagnosis

Parks 3-step test.
Kumar A
Indian J Ophthalmol 2022 Aug;70(8):3167. doi: 10.4103/ijo.IJO_714_22. PMID: 35919015Free PMC Article
Comitant strabismus.
Schworm HD, Rudolph G
Curr Opin Ophthalmol 2000 Oct;11(5):310-7. doi: 10.1097/00055735-200010000-00004. PMID: 11148695
Comitant strabismus.
de Faber JT, Kingma-Wilschut C, Grootendorst R
Curr Opin Ophthalmol 1999 Oct;10(5):305-9. doi: 10.1097/00055735-199910000-00004. PMID: 10621542
Infantile exotropia.
Biglan AW, Davis JS, Cheng KP, Pettapiece MC
J Pediatr Ophthalmol Strabismus 1996 Mar-Apr;33(2):79-84. doi: 10.3928/0191-3913-19960301-04. PMID: 8965243
Congenital esotropia.
Nelson LB, Wagner RS, Simon JW, Harley RD
Surv Ophthalmol 1987 May-Jun;31(6):363-83. doi: 10.1016/0039-6257(87)90030-0. PMID: 3303394

Therapy

Interventions for infantile esotropia.
Mehner L, Ng SM, Singh J
Cochrane Database Syst Rev 2023 Jan 16;1(1):CD004917. doi: 10.1002/14651858.CD004917.pub4. PMID: 36645238Free PMC Article
Interventions for dissociated vertical deviation.
Hatt SR, Wang X, Holmes JM
Cochrane Database Syst Rev 2015 Nov 20;2015(11):CD010868. doi: 10.1002/14651858.CD010868.pub2. PMID: 26587695Free PMC Article
Use of botulinum toxin in strabismus.
Crouch ER
Curr Opin Ophthalmol 2006 Oct;17(5):435-40. doi: 10.1097/01.icu.0000243018.97627.4c. PMID: 16932060
Comitant strabismus.
Schworm HD, Rudolph G
Curr Opin Ophthalmol 2000 Oct;11(5):310-7. doi: 10.1097/00055735-200010000-00004. PMID: 11148695
Congenital esotropia.
Nelson LB, Wagner RS, Simon JW, Harley RD
Surv Ophthalmol 1987 May-Jun;31(6):363-83. doi: 10.1016/0039-6257(87)90030-0. PMID: 3303394

Prognosis

Infantile Esoropia: Management results and prognostic factors.
Lajmi H, El Fekih L, Khlifi K, Wassim H
Tunis Med 2021 Décembre;99(12):1180-1187. PMID: 35288925Free PMC Article
Bilateral Symmetric and Asymmetric Superior Rectus Recession for Patients with Dissociated Vertical Deviation.
Tibrewal S, Nguyen PTT, Ganesh S, Molinari A
Asia Pac J Ophthalmol (Phila) 2019 May-Jun;8(3):218-223. Epub 2019 May 15 doi: 10.22608/APO.2018415. PMID: 31090282
Understanding ocular torticollis in children.
Boricean ID, Bărar A
Oftalmologia 2011;55(1):10-26. PMID: 21774381
Comitant strabismus.
Schworm HD, Rudolph G
Curr Opin Ophthalmol 2000 Oct;11(5):310-7. doi: 10.1097/00055735-200010000-00004. PMID: 11148695
Early-onset accommodative esotropia.
Havertape SA, Whitfill CR, Cruz OA
J Pediatr Ophthalmol Strabismus 1999 Mar-Apr;36(2):69-73. doi: 10.3928/0191-3913-19990301-05. PMID: 10204132

Clinical prediction guides

Interventions for infantile esotropia.
Mehner L, Ng SM, Singh J
Cochrane Database Syst Rev 2023 Jan 16;1(1):CD004917. doi: 10.1002/14651858.CD004917.pub4. PMID: 36645238Free PMC Article
Unilateral Surgery in Bilateral Asymmetrical Dissociated Vertical Deviation With Strong Preferential Fixation.
Lembo A, Serafino M, Villani E, Nucci P
J Pediatr Ophthalmol Strabismus 2022 Jan-Feb;59(1):60-64. Epub 2021 Sep 30 doi: 10.3928/01913913-20210708-06. PMID: 34592873
Stereopsis in children with intermittent exotropia and dissociated vertical deviation.
Klaehn LD, Kramer AM, Hodge DO, Mohney BG
J AAPOS 2021 Oct;25(5):300-301. Epub 2021 Aug 20 doi: 10.1016/j.jaapos.2021.05.005. PMID: 34425236
Bilateral hypotropic dissociated vertical deviation: a case report.
Shohadeh N, Alhalabi N
J Med Case Rep 2020 Dec 10;14(1):241. doi: 10.1186/s13256-020-02567-7. PMID: 33303002Free PMC Article
Comparison of Clinical Features and Long-term Surgical Outcomes in Infantile Constant and Intermittent Exotropia.
Na KH, Kim SH
J Pediatr Ophthalmol Strabismus 2016 Mar-Apr;53(2):99-104. Epub 2016 Feb 4 doi: 10.3928/01913913-20160122-05. PMID: 26848593

Recent systematic reviews

Interventions for infantile esotropia.
Mehner L, Ng SM, Singh J
Cochrane Database Syst Rev 2023 Jan 16;1(1):CD004917. doi: 10.1002/14651858.CD004917.pub4. PMID: 36645238Free PMC Article
Interventions for dissociated vertical deviation.
Hatt SR, Wang X, Holmes JM
Cochrane Database Syst Rev 2015 Nov 20;2015(11):CD010868. doi: 10.1002/14651858.CD010868.pub2. PMID: 26587695Free PMC Article

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