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Pharynx cancer

MedGen UID:
57554
•Concept ID:
C0153405
•
Neoplastic Process
Synonyms: Cancer of Pharynx; Cancer of the Pharynx; Cancer, Pharnyx; Cancer, Pharyngeal; Cancers, Pharnyx; Cancers, Pharyngeal; Pharnyx Cancer; Pharnyx Cancers; Pharyngeal Cancer; Pharyngeal Cancers; Pharynx Cancer; Pharynx Cancers
SNOMED CT: Cancer of pharynx (363507003); CA - Cancer of pharynx (363507003); Malignant neoplasm of pharynx (363507003); Malignant tumor of pharynx (363507003)
 
Monarch Initiative: MONDO:0005517

Definition

A primary or metastatic malignant neoplasm that affects the pharynx. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPharynx cancer

Professional guidelines

PubMed

Surgical treatment of cervical spondylodiscitis: a review of 30 consecutive patients.
Shousha M, Boehm H
Spine (Phila Pa 1976) 2012 Jan 1;37(1):E30-6. doi: 10.1097/BRS.0b013e31821bfdb2. PMID: 21494200
Scattered doses to different parts of cancer patients during radiotherapy treatment in Nigeria.
Ogundare FO, Ademola JA
Radiat Prot Dosimetry 2002;102(1):71-4. doi: 10.1093/oxfordjournals.rpd.a006076. PMID: 12212905

Recent clinical studies

Etiology

ALDH2 polymorphism, alcohol intake and the attributable burden of cancer in East Asia: systematic review, meta-analysis, and modeling study.
Ng CS, Ong XJ, Au M, Lau YH, Kwok HHY, Quan J
Ann Epidemiol 2023 Sep;85:113-120.e20. Epub 2023 Jun 1 doi: 10.1016/j.annepidem.2023.05.013. PMID: 37268241
The association between oral hygiene and head and neck cancer: a meta-analysis.
Bai X, Cui C, Yin J, Li H, Gong Q, Wei B, Lu Y
Acta Odontol Scand 2023 Jul;81(5):374-395. Epub 2022 Dec 20 doi: 10.1080/00016357.2022.2158129. PMID: 36538375
Effect of Periodontitis and Scaling and Root Planing on Risk of Pharyngeal Cancer: A Nested Case-Control Study.
Chen PJ, Chen YY, Lin CW, Yeh YT, Yeh HW, Huang JY, Yang SF, Yeh CB
Int J Environ Res Public Health 2020 Dec 22;18(1) doi: 10.3390/ijerph18010008. PMID: 33375028Free PMC Article
A spatial study of oral & pharynx cancer mortality and incidence in the U.S.A.: 2000-2015.
Amin RW, Rivera B
Sci Total Environ 2020 Apr 15;713:136688. Epub 2020 Jan 15 doi: 10.1016/j.scitotenv.2020.136688. PMID: 32019034
An Ecological Analysis of Tobacco Use and Oral Cavity and Pharynx Cancers in U.S. Males.
Damphousse KE, Mowls DS, Beebe LA
J Okla State Med Assoc 2015 Nov;108(11):488-91. PMID: 26817067

Diagnosis

Head and Neck Cancer Incidence in the United States Before and During the COVID-19 Pandemic.
Semprini J, Pagedar NA, Boakye EA, Osazuwa-Peters N
JAMA Otolaryngol Head Neck Surg 2024 Mar 1;150(3):193-200. doi: 10.1001/jamaoto.2023.4322. PMID: 38206603Free PMC Article
Effect of Periodontitis and Scaling and Root Planing on Risk of Pharyngeal Cancer: A Nested Case-Control Study.
Chen PJ, Chen YY, Lin CW, Yeh YT, Yeh HW, Huang JY, Yang SF, Yeh CB
Int J Environ Res Public Health 2020 Dec 22;18(1) doi: 10.3390/ijerph18010008. PMID: 33375028Free PMC Article
An Ecological Analysis of Tobacco Use and Oral Cavity and Pharynx Cancers in U.S. Males.
Damphousse KE, Mowls DS, Beebe LA
J Okla State Med Assoc 2015 Nov;108(11):488-91. PMID: 26817067
Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium.
Leoncini E, Ricciardi W, Cadoni G, Arzani D, Petrelli L, Paludetti G, Brennan P, Luce D, Stucker I, Matsuo K, Talamini R, La Vecchia C, Olshan AF, Winn DM, Herrero R, Franceschi S, Castellsague X, Muscat J, Morgenstern H, Zhang ZF, Levi F, Dal Maso L, Kelsey K, McClean M, Vaughan TL, Lazarus P, Purdue MP, Hayes RB, Chen C, Schwartz SM, Shangina O, Koifman S, Ahrens W, Matos E, Lagiou P, Lissowska J, Szeszenia-Dabrowska N, Fernandez L, Menezes A, Agudo A, Daudt AW, Richiardi L, Kjaerheim K, Mates D, Betka J, Yu GP, Schantz S, Simonato L, Brenner H, Conway DI, Macfarlane TV, Thomson P, Fabianova E, Znaor A, Rudnai P, Healy C, Boffetta P, Chuang SC, Lee YC, Hashibe M, Boccia S
Eur J Epidemiol 2014 Jan;29(1):35-48. Epub 2013 Nov 24 doi: 10.1007/s10654-013-9863-2. PMID: 24271556Free PMC Article
Impact of delay in diagnosis on survival to head and neck carcinomas: a systematic review with meta-analysis.
Seoane J, Takkouche B, Varela-Centelles P, Tomás I, Seoane-Romero JM
Clin Otolaryngol 2012 Apr;37(2):99-106. doi: 10.1111/j.1749-4486.2012.02464.x. PMID: 22429704

Therapy

ALDH2 polymorphism, alcohol intake and the attributable burden of cancer in East Asia: systematic review, meta-analysis, and modeling study.
Ng CS, Ong XJ, Au M, Lau YH, Kwok HHY, Quan J
Ann Epidemiol 2023 Sep;85:113-120.e20. Epub 2023 Jun 1 doi: 10.1016/j.annepidem.2023.05.013. PMID: 37268241
Effects of Bauxite and Alumina Exposure on Incidence of Cancer - Meta-analysis.
Thevi T , Abas AL
Kathmandu Univ Med J (KUMJ) 2020 Oct.-Dec.;18(72):414-419. PMID: 34165102
A spatial study of oral & pharynx cancer mortality and incidence in the U.S.A.: 2000-2015.
Amin RW, Rivera B
Sci Total Environ 2020 Apr 15;713:136688. Epub 2020 Jan 15 doi: 10.1016/j.scitotenv.2020.136688. PMID: 32019034
An Ecological Analysis of Tobacco Use and Oral Cavity and Pharynx Cancers in U.S. Males.
Damphousse KE, Mowls DS, Beebe LA
J Okla State Med Assoc 2015 Nov;108(11):488-91. PMID: 26817067
Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium.
Leoncini E, Ricciardi W, Cadoni G, Arzani D, Petrelli L, Paludetti G, Brennan P, Luce D, Stucker I, Matsuo K, Talamini R, La Vecchia C, Olshan AF, Winn DM, Herrero R, Franceschi S, Castellsague X, Muscat J, Morgenstern H, Zhang ZF, Levi F, Dal Maso L, Kelsey K, McClean M, Vaughan TL, Lazarus P, Purdue MP, Hayes RB, Chen C, Schwartz SM, Shangina O, Koifman S, Ahrens W, Matos E, Lagiou P, Lissowska J, Szeszenia-Dabrowska N, Fernandez L, Menezes A, Agudo A, Daudt AW, Richiardi L, Kjaerheim K, Mates D, Betka J, Yu GP, Schantz S, Simonato L, Brenner H, Conway DI, Macfarlane TV, Thomson P, Fabianova E, Znaor A, Rudnai P, Healy C, Boffetta P, Chuang SC, Lee YC, Hashibe M, Boccia S
Eur J Epidemiol 2014 Jan;29(1):35-48. Epub 2013 Nov 24 doi: 10.1007/s10654-013-9863-2. PMID: 24271556Free PMC Article

Prognosis

Head and Neck Cancer Incidence in the United States Before and During the COVID-19 Pandemic.
Semprini J, Pagedar NA, Boakye EA, Osazuwa-Peters N
JAMA Otolaryngol Head Neck Surg 2024 Mar 1;150(3):193-200. doi: 10.1001/jamaoto.2023.4322. PMID: 38206603Free PMC Article
Incidence and mortality rates of lip, oral cavity, and pharynx cancers in Brazil: time-trend and age-period-cohort analysis from the last 30 years, Global Burden of Disease Study.
Romagna DV, Oliveira MM, Abreu LG, Stein C, Hugo FN, Teixeira R, Malta DC, Naghavi M, Iser BPM
Rev Soc Bras Med Trop 2022;55(suppl 1):e0286. Epub 2022 Jan 28 doi: 10.1590/0037-8682-0286-2021. PMID: 35107536Free PMC Article
Effects of Bauxite and Alumina Exposure on Incidence of Cancer - Meta-analysis.
Thevi T , Abas AL
Kathmandu Univ Med J (KUMJ) 2020 Oct.-Dec.;18(72):414-419. PMID: 34165102
A spatial study of oral & pharynx cancer mortality and incidence in the U.S.A.: 2000-2015.
Amin RW, Rivera B
Sci Total Environ 2020 Apr 15;713:136688. Epub 2020 Jan 15 doi: 10.1016/j.scitotenv.2020.136688. PMID: 32019034
An Ecological Analysis of Tobacco Use and Oral Cavity and Pharynx Cancers in U.S. Males.
Damphousse KE, Mowls DS, Beebe LA
J Okla State Med Assoc 2015 Nov;108(11):488-91. PMID: 26817067

Clinical prediction guides

Head and Neck Cancer Incidence in the United States Before and During the COVID-19 Pandemic.
Semprini J, Pagedar NA, Boakye EA, Osazuwa-Peters N
JAMA Otolaryngol Head Neck Surg 2024 Mar 1;150(3):193-200. doi: 10.1001/jamaoto.2023.4322. PMID: 38206603Free PMC Article
Effect of Periodontitis and Scaling and Root Planing on Risk of Pharyngeal Cancer: A Nested Case-Control Study.
Chen PJ, Chen YY, Lin CW, Yeh YT, Yeh HW, Huang JY, Yang SF, Yeh CB
Int J Environ Res Public Health 2020 Dec 22;18(1) doi: 10.3390/ijerph18010008. PMID: 33375028Free PMC Article
An Ecological Analysis of Tobacco Use and Oral Cavity and Pharynx Cancers in U.S. Males.
Damphousse KE, Mowls DS, Beebe LA
J Okla State Med Assoc 2015 Nov;108(11):488-91. PMID: 26817067
Measuring side effects after radiotherapy for pharynx cancer.
Jensen K
Acta Oncol 2007;46(8):1051-63. doi: 10.1080/02841860701481547. PMID: 17882557
The epidemiology of oral and pharynx cancer in Brazil.
Wünsch-Filho V
Oral Oncol 2002 Dec;38(8):737-46. doi: 10.1016/s1368-8375(02)00066-0. PMID: 12570051

Recent systematic reviews

Health effects associated with chewing tobacco: a Burden of Proof study.
Gil GF, Anderson JA, Aravkin A, Bhangdia K, Carr S, Dai X, Flor LS, Hay SI, Malloy MJ, McLaughlin SA, Mullany EC, Murray CJL, O'Connell EM, Okereke C, Sorensen RJD, Whisnant J, Zheng P, Gakidou E
Nat Commun 2024 Feb 5;15(1):1082. doi: 10.1038/s41467-024-45074-9. PMID: 38316758Free PMC Article
ALDH2 polymorphism, alcohol intake and the attributable burden of cancer in East Asia: systematic review, meta-analysis, and modeling study.
Ng CS, Ong XJ, Au M, Lau YH, Kwok HHY, Quan J
Ann Epidemiol 2023 Sep;85:113-120.e20. Epub 2023 Jun 1 doi: 10.1016/j.annepidem.2023.05.013. PMID: 37268241
Cancers of the Oral Cavity and Pharynx: 20-Year Comparative Survival and Mortality Analysis by Age, Sex, Race, Stage, Grade, Cohort Entry Time-Period and Disease Duration: A Systematic Review of 218,066 Cases for Diagnosis Years 1973-2014: (SEER*Stat 8.3.5).
Milano AF
J Insur Med 2022 Jul 1;49(3):147-171. doi: 10.17849/insm-49-3-147-171.1. PMID: 36378890
Alcohol-based mouthwash as a risk factor of oral cancer: A systematic review.
Ustrell-Borràs M, Traboulsi-Garet B, Gay-Escoda C
Med Oral Patol Oral Cir Bucal 2020 Jan 1;25(1):e1-e12. doi: 10.4317/medoral.23085. PMID: 31655832Free PMC Article
Impact of delay in diagnosis on survival to head and neck carcinomas: a systematic review with meta-analysis.
Seoane J, Takkouche B, Varela-Centelles P, Tomás I, Seoane-Romero JM
Clin Otolaryngol 2012 Apr;37(2):99-106. doi: 10.1111/j.1749-4486.2012.02464.x. PMID: 22429704

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