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Malignant cranial nerve neoplasm

MedGen UID:
57567
•Concept ID:
C0153644
•
Neoplastic Process
Synonyms: Cranial Nerve Neoplasms, Malignant; Cranial Nerve Tumors, Malignant; Malignant Cranial Nerve Neoplasms; Malignant Cranial Nerve Tumors; Neoplasms, Cranial Nerve, Malignant; Tumors, Cranial Nerve, Malignant
SNOMED CT: Malignant tumor of cranial nerve (188307009)
 
Monarch Initiative: MONDO:0002433

Definition

A primary or metastatic malignant neoplasm that affects a cranial nerve. [from NCI]

Professional guidelines

PubMed

Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation.
Plotkin SR, Messiaen L, Legius E, Pancza P, Avery RA, Blakeley JO, Babovic-Vuksanovic D, Ferner R, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Hanemann CO, Kalamarides M, Kehrer-Sawatzki H, Korf BR, Mautner VF, MacCollin M, Papi L, Rauen KA, Riccardi V, Schorry E, Smith MJ, Stemmer-Rachamimov A, Stevenson DA, Ullrich NJ, Viskochil D, Wimmer K, Yohay K; International Consensus Group on Neurofibromatosis Diagnostic Criteria (I-NF-DC), Huson SM, Wolkenstein P, Evans DG
Genet Med 2022 Sep;24(9):1967-1977. Epub 2022 Jun 9 doi: 10.1016/j.gim.2022.05.007. PMID: 35674741
EANO guideline on the diagnosis and treatment of vestibular schwannoma.
Goldbrunner R, Weller M, Regis J, Lund-Johansen M, Stavrinou P, Reuss D, Evans DG, Lefranc F, Sallabanda K, Falini A, Axon P, Sterkers O, Fariselli L, Wick W, Tonn JC
Neuro Oncol 2020 Jan 11;22(1):31-45. doi: 10.1093/neuonc/noz153. PMID: 31504802Free PMC Article
Current treatment of optic nerve gliomas.
Farazdaghi MK, Katowitz WR, Avery RA
Curr Opin Ophthalmol 2019 Sep;30(5):356-363. doi: 10.1097/ICU.0000000000000587. PMID: 31246635Free PMC Article

Recent clinical studies

Etiology

Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
Intratemporal facial nerve schwannomas: multicenter experience of 80 cases.
Loos E, Verhaert N, Darrouzet V, Godey B, Linder T, Vincent C, Lavieille JP, Schmerber S, Lescanne E, Trabalzini F, De Foer B, Van Havenbergh T, Somers T
Eur Arch Otorhinolaryngol 2020 Aug;277(8):2209-2217. Epub 2020 Apr 11 doi: 10.1007/s00405-020-05960-6. PMID: 32279104
Peripheral and cranial nerve sheath tumors.
Mrugala MM, Batchelor TT, Plotkin SR
Curr Opin Neurol 2005 Oct;18(5):604-10. doi: 10.1097/01.wco.0000179507.51647.02. PMID: 16155448
Bilateral acoustic neuromas.
Anand VT, Byrnes DP, Walby AP, Kerr AG
Clin Otolaryngol Allied Sci 1993 Oct;18(5):365-71. doi: 10.1111/j.1365-2273.1993.tb00594.x. PMID: 8877201
Clinoidal meningiomas.
al-Mefty O, Ayoubi S
Acta Neurochir Suppl (Wien) 1991;53:92-7. doi: 10.1007/978-3-7091-9183-5_16. PMID: 1803892

Diagnosis

Trigeminal neuromas: modern diagnosis and treatment.
Bezborodova TY, Zolotova SV
Zh Vopr Neirokhir Im N N Burdenko 2023;87(1):104-110. doi: 10.17116/neiro202387011104. PMID: 36763561
Oculomotor nerve schwannoma: case series and literature review.
Douglas VP, Flores C, Douglas KA, Strominger MB, Kasper E, Torun N
Surv Ophthalmol 2022 Jul-Aug;67(4):1160-1174. Epub 2021 Nov 21 doi: 10.1016/j.survophthal.2021.11.008. PMID: 34813853
Perineural tumor spread.
Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E
Neuroimaging Clin N Am 2008 May;18(2):413-29, xi. doi: 10.1016/j.nic.2008.01.001. PMID: 18466839
Vagal paragangliomas.
Sniezek JC, Netterville JL, Sabri AN
Otolaryngol Clin North Am 2001 Oct;34(5):925-39, vi. doi: 10.1016/s0030-6665(05)70355-8. PMID: 11557447
Olfactory neuroblastoma.
Baker DC, Perzin KH, Conley J
Otolaryngol Head Neck Surg (1979) 1979 May-Jun;87(3):279-83. doi: 10.1177/019459987908700301. PMID: 492698

Therapy

A Critical Overview of Targeted Therapies for Vestibular Schwannoma.
Tamura R, Toda M
Int J Mol Sci 2022 May 13;23(10) doi: 10.3390/ijms23105462. PMID: 35628268Free PMC Article
Current Understanding of Neurofibromatosis Type 1, 2, and Schwannomatosis.
Tamura R
Int J Mol Sci 2021 May 29;22(11) doi: 10.3390/ijms22115850. PMID: 34072574Free PMC Article
Vestibular Schwannomas.
Carlson ML, Link MJ
N Engl J Med 2021 Apr 8;384(14):1335-1348. doi: 10.1056/NEJMra2020394. PMID: 33826821
Current treatment of optic nerve gliomas.
Farazdaghi MK, Katowitz WR, Avery RA
Curr Opin Ophthalmol 2019 Sep;30(5):356-363. doi: 10.1097/ICU.0000000000000587. PMID: 31246635Free PMC Article
Chemotherapy: present and future.
Terry AR, Plotkin SR
Otolaryngol Clin North Am 2012 Apr;45(2):471-86, x. doi: 10.1016/j.otc.2011.12.013. PMID: 22483828

Prognosis

Intratemporal facial nerve schwannomas: multicenter experience of 80 cases.
Loos E, Verhaert N, Darrouzet V, Godey B, Linder T, Vincent C, Lavieille JP, Schmerber S, Lescanne E, Trabalzini F, De Foer B, Van Havenbergh T, Somers T
Eur Arch Otorhinolaryngol 2020 Aug;277(8):2209-2217. Epub 2020 Apr 11 doi: 10.1007/s00405-020-05960-6. PMID: 32279104
Cranial Nerve Schwannomas: Diagnostic Imaging Approach.
Skolnik AD, Loevner LA, Sampathu DM, Newman JG, Lee JY, Bagley LJ, Learned KO
Radiographics 2016 Sep-Oct;36(5):1463-77. Epub 2016 Aug 19 doi: 10.1148/rg.2016150199. PMID: 27541436
Malignant peripheral nerve sheath tumors of the eighth cranial nerve arising without prior irradiation.
Carlson ML, Jacob JT, Habermann EB, Glasgow AE, Raghunathan A, Link MJ
J Neurosurg 2016 Nov;125(5):1120-1129. Epub 2016 Jan 8 doi: 10.3171/2015.7.JNS151056. PMID: 26745487
Perineural tumor spread.
Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E
Neuroimaging Clin N Am 2008 May;18(2):413-29, xi. doi: 10.1016/j.nic.2008.01.001. PMID: 18466839
Vagal paragangliomas.
Sniezek JC, Netterville JL, Sabri AN
Otolaryngol Clin North Am 2001 Oct;34(5):925-39, vi. doi: 10.1016/s0030-6665(05)70355-8. PMID: 11557447

Clinical prediction guides

Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
EANO guideline on the diagnosis and treatment of vestibular schwannoma.
Goldbrunner R, Weller M, Regis J, Lund-Johansen M, Stavrinou P, Reuss D, Evans DG, Lefranc F, Sallabanda K, Falini A, Axon P, Sterkers O, Fariselli L, Wick W, Tonn JC
Neuro Oncol 2020 Jan 11;22(1):31-45. doi: 10.1093/neuonc/noz153. PMID: 31504802Free PMC Article
Intratemporal facial nerve schwannoma: clinical presentation and management.
Lahlou G, Nguyen Y, Russo FY, Ferrary E, Sterkers O, Bernardeschi D
Eur Arch Otorhinolaryngol 2016 Nov;273(11):3497-3504. Epub 2015 Dec 16 doi: 10.1007/s00405-015-3850-z. PMID: 26676873
Hearing preservation: microsurgery.
Kari E, Friedman RA
Curr Opin Otolaryngol Head Neck Surg 2012 Oct;20(5):358-66. doi: 10.1097/MOO.0b013e3283579673. PMID: 22929113
Vestibular neurectomy.
Thomsen J, Berner B, Tos M
Auris Nasus Larynx 2000 Oct;27(4):297-301. doi: 10.1016/s0385-8146(00)00076-6. PMID: 10996487

Recent systematic reviews

Surgical Treatment of Trochlear Nerve Schwannomas: Case Series and Systematic Review.
Ozoner B, Gungor A, Ture H, Ture U
World Neurosurg 2022 Jun;162:e288-e300. Epub 2022 Mar 9 doi: 10.1016/j.wneu.2022.03.006. PMID: 35276398
Treatment for vestibular schwannoma: Systematic review and single arm meta-analysis.
Thai NLB, Mai NY, Vuong NL, Tin NM, Karam D, Refaey MA, Shahin KM, Soliman AL, Al Khudari R, Thuan TM, Sabbah GM, El-Qushayri AE, Karimzadeh S, Hirayama K, Huy NT
Am J Otolaryngol 2022 Mar-Apr;43(2):103337. Epub 2021 Dec 20 doi: 10.1016/j.amjoto.2021.103337. PMID: 34973662
Metastatic Lesions of the Clivus: A Systematic Review.
Jozsa F, Das JM
World Neurosurg 2022 Feb;158:190-204. Epub 2021 Nov 30 doi: 10.1016/j.wneu.2021.11.105. PMID: 34861450
Indications and contraindications of auditory brainstem implants: systematic review and illustrative cases.
Merkus P, Di Lella F, Di Trapani G, Pasanisi E, Beltrame MA, Zanetti D, Negri M, Sanna M
Eur Arch Otorhinolaryngol 2014 Jan;271(1):3-13. Epub 2013 Feb 13 doi: 10.1007/s00405-013-2378-3. PMID: 23404468
Malignant mental nerve neuropathy: systematic review.
Galán Gil S, Peñarrocha Diago M, Peñarrocha Diago M
Med Oral Patol Oral Cir Bucal 2008 Oct 1;13(10):E616-21. PMID: 18830167

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