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Ampulla of vater cancer

MedGen UID:
57785
•Concept ID:
C0153454
•
Neoplastic Process
Synonyms: ampulla of vater cancer; cancer of hepatopancreatic ampulla; hepatopancreatic ampulla cancer; Malignant Ampulla of Vater Neoplasm; malignant ampulla of Vater neoplasm; Malignant Ampulla of Vater Tumor; malignant ampulla of Vater tumor; malignant ampulla of Vater tumour; malignant hepatopancreatic ampulla neoplasm; Malignant Neoplasm of Ampulla of Vater; malignant neoplasm of ampulla of Vater; malignant neoplasm of hepatopancreatic ampulla; Malignant Neoplasm of the Ampulla of Vater; malignant neoplasm of the ampulla of Vater; Malignant tumor of ampulla of Vater; Malignant Tumor of Ampulla of Vater; malignant tumor of ampulla of Vater; malignant tumor of ampulla of vater; Malignant Tumor of the Ampulla of Vater; malignant tumor of the ampulla of Vater; malignant tumour of ampulla of vater; malignant tumour of ampulla of Vater; malignant tumour of the ampulla of Vater
SNOMED CT: Malignant tumor of ampulla of Vater (363417006)
 
Monarch Initiative: MONDO:0000919

Definition

A primary or metastatic malignant neoplasm involving the ampulla of Vater. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines

PubMed

Adjuvant systemic treatment in resected biliary tract cancer: State of the art, controversies, and future directions.
Rizzo A, Brandi G
Cancer Treat Res Commun 2021;27:100334. Epub 2021 Feb 12 doi: 10.1016/j.ctarc.2021.100334. PMID: 33592563
Nivolumab: an investigational agent for the treatment of biliary tract cancer.
Di Federico A, Rizzo A, Ricci AD, Frega G, Palloni A, Tavolari S, Brandi G
Expert Opin Investig Drugs 2021 Apr;30(4):325-332. Epub 2020 Dec 23 doi: 10.1080/13543784.2021.1863946. PMID: 33307866
Futibatinib, an investigational agent for the treatment of intrahepatic cholangiocarcinoma: evidence to date and future perspectives.
Rizzo A, Ricci AD, Brandi G
Expert Opin Investig Drugs 2021 Apr;30(4):317-324. Epub 2020 Oct 25 doi: 10.1080/13543784.2021.1837774. PMID: 33054456

Recent clinical studies

Etiology

Impact of histopathological type on the prognosis of ampullary carcinoma: A systematic review and meta-analysis.
Shin DW, Kim S, Jung K, Jung JH, Kim B, Ahn J, Kim J, Hwang JH, Lee JC
Eur J Surg Oncol 2023 Feb;49(2):306-315. Epub 2022 Oct 9 doi: 10.1016/j.ejso.2022.10.001. PMID: 36272870
Neoadjuvant therapy for cholangiocarcinoma: A comprehensive literature review.
Rizzo A, Brandi G
Cancer Treat Res Commun 2021;27:100354. Epub 2021 Mar 16 doi: 10.1016/j.ctarc.2021.100354. PMID: 33756174
Recent advances of immunotherapy for biliary tract cancer.
Rizzo A, Ricci AD, Brandi G
Expert Rev Gastroenterol Hepatol 2021 May;15(5):527-536. Epub 2021 Jan 8 doi: 10.1080/17474124.2021.1853527. PMID: 33215952
Targeting BRAF-Mutant Biliary Tract Cancer: Recent Advances and Future Challenges.
Rizzo A, Federico AD, Ricci AD, Frega G, Palloni A, Pagani R, Tavolari S, Marco MD, Brandi G
Cancer Control 2020 Jan-Dec;27(1):1073274820983013. doi: 10.1177/1073274820983013. PMID: 33356500Free PMC Article
Smoking, Alcohol, and Biliary Tract Cancer Risk: A Pooling Project of 26 Prospective Studies.
McGee EE, Jackson SS, Petrick JL, Van Dyke AL, Adami HO, Albanes D, Andreotti G, Beane-Freeman LE, Berrington de Gonzalez A, Buring JE, Chan AT, Chen Y, Fraser GE, Freedman ND, Gao YT, Gapstur SM, Gaziano JM, Giles GG, Grant EJ, Grodstein F, Hartge P, Jenab M, Kitahara CM, Knutsen SF, Koh WP, Larsson SC, Lee IM, Liao LM, Luo J, Milne RL, Monroe KR, Neuhouser ML, O'Brien KM, Peters U, Poynter JN, Purdue MP, Robien K, Sandler DP, Sawada N, Schairer C, Sesso HD, Simon TG, Sinha R, Stolzenberg-Solomon R, Tsugane S, Wang R, Weiderpass E, Weinstein SJ, White E, Wolk A, Yuan JM, Zeleniuch-Jacquotte A, Zhang X, Zhu B, McGlynn KA, Campbell PT, Koshiol J
J Natl Cancer Inst 2019 Dec 1;111(12):1263-1278. doi: 10.1093/jnci/djz103. PMID: 31127946Free PMC Article

Diagnosis

Descriptive epidemiology of biliary tract cancer incidence and geographic variation in Japan.
Makiuchi T, Sobue T
Eur J Cancer Prev 2023 Jan 1;32(1):2-9. Epub 2022 Apr 26 doi: 10.1097/CEJ.0000000000000758. PMID: 35485392
Neoadjuvant therapy for cholangiocarcinoma: A comprehensive literature review.
Rizzo A, Brandi G
Cancer Treat Res Commun 2021;27:100354. Epub 2021 Mar 16 doi: 10.1016/j.ctarc.2021.100354. PMID: 33756174
Nivolumab: an investigational agent for the treatment of biliary tract cancer.
Di Federico A, Rizzo A, Ricci AD, Frega G, Palloni A, Tavolari S, Brandi G
Expert Opin Investig Drugs 2021 Apr;30(4):325-332. Epub 2020 Dec 23 doi: 10.1080/13543784.2021.1863946. PMID: 33307866
Recent advances of immunotherapy for biliary tract cancer.
Rizzo A, Ricci AD, Brandi G
Expert Rev Gastroenterol Hepatol 2021 May;15(5):527-536. Epub 2021 Jan 8 doi: 10.1080/17474124.2021.1853527. PMID: 33215952
Targeting BRAF-Mutant Biliary Tract Cancer: Recent Advances and Future Challenges.
Rizzo A, Federico AD, Ricci AD, Frega G, Palloni A, Pagani R, Tavolari S, Marco MD, Brandi G
Cancer Control 2020 Jan-Dec;27(1):1073274820983013. doi: 10.1177/1073274820983013. PMID: 33356500Free PMC Article

Therapy

Neoadjuvant therapy for cholangiocarcinoma: A comprehensive literature review.
Rizzo A, Brandi G
Cancer Treat Res Commun 2021;27:100354. Epub 2021 Mar 16 doi: 10.1016/j.ctarc.2021.100354. PMID: 33756174
Nivolumab: an investigational agent for the treatment of biliary tract cancer.
Di Federico A, Rizzo A, Ricci AD, Frega G, Palloni A, Tavolari S, Brandi G
Expert Opin Investig Drugs 2021 Apr;30(4):325-332. Epub 2020 Dec 23 doi: 10.1080/13543784.2021.1863946. PMID: 33307866
Recent advances of immunotherapy for biliary tract cancer.
Rizzo A, Ricci AD, Brandi G
Expert Rev Gastroenterol Hepatol 2021 May;15(5):527-536. Epub 2021 Jan 8 doi: 10.1080/17474124.2021.1853527. PMID: 33215952
Targeting BRAF-Mutant Biliary Tract Cancer: Recent Advances and Future Challenges.
Rizzo A, Federico AD, Ricci AD, Frega G, Palloni A, Pagani R, Tavolari S, Marco MD, Brandi G
Cancer Control 2020 Jan-Dec;27(1):1073274820983013. doi: 10.1177/1073274820983013. PMID: 33356500Free PMC Article
Smoking, Alcohol, and Biliary Tract Cancer Risk: A Pooling Project of 26 Prospective Studies.
McGee EE, Jackson SS, Petrick JL, Van Dyke AL, Adami HO, Albanes D, Andreotti G, Beane-Freeman LE, Berrington de Gonzalez A, Buring JE, Chan AT, Chen Y, Fraser GE, Freedman ND, Gao YT, Gapstur SM, Gaziano JM, Giles GG, Grant EJ, Grodstein F, Hartge P, Jenab M, Kitahara CM, Knutsen SF, Koh WP, Larsson SC, Lee IM, Liao LM, Luo J, Milne RL, Monroe KR, Neuhouser ML, O'Brien KM, Peters U, Poynter JN, Purdue MP, Robien K, Sandler DP, Sawada N, Schairer C, Sesso HD, Simon TG, Sinha R, Stolzenberg-Solomon R, Tsugane S, Wang R, Weiderpass E, Weinstein SJ, White E, Wolk A, Yuan JM, Zeleniuch-Jacquotte A, Zhang X, Zhu B, McGlynn KA, Campbell PT, Koshiol J
J Natl Cancer Inst 2019 Dec 1;111(12):1263-1278. doi: 10.1093/jnci/djz103. PMID: 31127946Free PMC Article

Prognosis

Impact of histopathological type on the prognosis of ampullary carcinoma: A systematic review and meta-analysis.
Shin DW, Kim S, Jung K, Jung JH, Kim B, Ahn J, Kim J, Hwang JH, Lee JC
Eur J Surg Oncol 2023 Feb;49(2):306-315. Epub 2022 Oct 9 doi: 10.1016/j.ejso.2022.10.001. PMID: 36272870
Descriptive epidemiology of biliary tract cancer incidence and geographic variation in Japan.
Makiuchi T, Sobue T
Eur J Cancer Prev 2023 Jan 1;32(1):2-9. Epub 2022 Apr 26 doi: 10.1097/CEJ.0000000000000758. PMID: 35485392
The epidemiological trends of biliary tract cancers in the United States of America.
Jiang Y, Jiang L, Li F, Li Q, Yuan S, Huang S, Fu Y, Yan X, Chen J, Li H, Li S, Liu J
BMC Gastroenterol 2022 Dec 29;22(1):546. doi: 10.1186/s12876-022-02637-8. PMID: 36581813Free PMC Article
Neoadjuvant therapy for cholangiocarcinoma: A comprehensive literature review.
Rizzo A, Brandi G
Cancer Treat Res Commun 2021;27:100354. Epub 2021 Mar 16 doi: 10.1016/j.ctarc.2021.100354. PMID: 33756174
Targeting BRAF-Mutant Biliary Tract Cancer: Recent Advances and Future Challenges.
Rizzo A, Federico AD, Ricci AD, Frega G, Palloni A, Pagani R, Tavolari S, Marco MD, Brandi G
Cancer Control 2020 Jan-Dec;27(1):1073274820983013. doi: 10.1177/1073274820983013. PMID: 33356500Free PMC Article

Clinical prediction guides

Impact of histopathological type on the prognosis of ampullary carcinoma: A systematic review and meta-analysis.
Shin DW, Kim S, Jung K, Jung JH, Kim B, Ahn J, Kim J, Hwang JH, Lee JC
Eur J Surg Oncol 2023 Feb;49(2):306-315. Epub 2022 Oct 9 doi: 10.1016/j.ejso.2022.10.001. PMID: 36272870
The epidemiological trends of biliary tract cancers in the United States of America.
Jiang Y, Jiang L, Li F, Li Q, Yuan S, Huang S, Fu Y, Yan X, Chen J, Li H, Li S, Liu J
BMC Gastroenterol 2022 Dec 29;22(1):546. doi: 10.1186/s12876-022-02637-8. PMID: 36581813Free PMC Article
Neoadjuvant therapy for cholangiocarcinoma: A comprehensive literature review.
Rizzo A, Brandi G
Cancer Treat Res Commun 2021;27:100354. Epub 2021 Mar 16 doi: 10.1016/j.ctarc.2021.100354. PMID: 33756174
Recent advances of immunotherapy for biliary tract cancer.
Rizzo A, Ricci AD, Brandi G
Expert Rev Gastroenterol Hepatol 2021 May;15(5):527-536. Epub 2021 Jan 8 doi: 10.1080/17474124.2021.1853527. PMID: 33215952
Smoking, Alcohol, and Biliary Tract Cancer Risk: A Pooling Project of 26 Prospective Studies.
McGee EE, Jackson SS, Petrick JL, Van Dyke AL, Adami HO, Albanes D, Andreotti G, Beane-Freeman LE, Berrington de Gonzalez A, Buring JE, Chan AT, Chen Y, Fraser GE, Freedman ND, Gao YT, Gapstur SM, Gaziano JM, Giles GG, Grant EJ, Grodstein F, Hartge P, Jenab M, Kitahara CM, Knutsen SF, Koh WP, Larsson SC, Lee IM, Liao LM, Luo J, Milne RL, Monroe KR, Neuhouser ML, O'Brien KM, Peters U, Poynter JN, Purdue MP, Robien K, Sandler DP, Sawada N, Schairer C, Sesso HD, Simon TG, Sinha R, Stolzenberg-Solomon R, Tsugane S, Wang R, Weiderpass E, Weinstein SJ, White E, Wolk A, Yuan JM, Zeleniuch-Jacquotte A, Zhang X, Zhu B, McGlynn KA, Campbell PT, Koshiol J
J Natl Cancer Inst 2019 Dec 1;111(12):1263-1278. doi: 10.1093/jnci/djz103. PMID: 31127946Free PMC Article

Recent systematic reviews

Impact of histopathological type on the prognosis of ampullary carcinoma: A systematic review and meta-analysis.
Shin DW, Kim S, Jung K, Jung JH, Kim B, Ahn J, Kim J, Hwang JH, Lee JC
Eur J Surg Oncol 2023 Feb;49(2):306-315. Epub 2022 Oct 9 doi: 10.1016/j.ejso.2022.10.001. PMID: 36272870
Statins associate with lower risk of biliary tract cancers: A systematic review and meta-analysis.
Cheung KS, Yeung YWM, Wong WS, Li B, Seto WK, Leung WK
Cancer Med 2023 Jan;12(1):557-568. Epub 2022 Jun 13 doi: 10.1002/cam4.4942. PMID: 35698295Free PMC Article
Association between gallstones and the risk of biliary tract cancer: a systematic review and meta-analysis.
Huang D, Joo H, Song N, Cho S, Kim W, Shin A
Epidemiol Health 2021;43:e2021011. Epub 2021 Feb 3 doi: 10.4178/epih.e2021011. PMID: 33541011Free PMC Article
Effects of aspirin and non-steroidal anti-inflammatory drugs on the risk of cholangiocarcinoma: a meta-analysis.
Lapumnuaypol K, Tiu A, Thongprayoon C, Wijarnpreecha K, Ungprasert P, Mao MA, Cheungpasitporn W
QJM 2019 Jun 1;112(6):421-427. doi: 10.1093/qjmed/hcz039. PMID: 30753687
Survival Benefit of Adjuvant Chemoradiotherapy in Patients With Ampulla of Vater Cancer: A Systematic Review and Meta-analysis.
Kwon J, Kim BH, Kim K, Chie EK, Ha SW
Ann Surg 2015 Jul;262(1):47-52. doi: 10.1097/SLA.0000000000001182. PMID: 25775067

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