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Lichen nitidus

MedGen UID:
58196
•Concept ID:
C0162849
•
Disease or Syndrome
Synonym: Lichen Nitidus
SNOMED CT: Lichen nitidus (41890004); Pinkus' disease (41890004)
 
Monarch Initiative: MONDO:0006571

Definition

A chronic inflammatory disease characterized by shiny, flat-topped, usually flesh-colored micropapules no larger than the head of a pin. Lesions are localized in the early stages, found chiefly on the lower abdomen, penis, and inner surface of the thighs. Distribution may become generalized as the disease progresses. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLichen nitidus

Recent clinical studies

Etiology

Pediatric lichen nitidus: A single-center experience.
Kundak S, Çakır Y
Pediatr Dermatol 2019 Mar;36(2):189-192. Epub 2019 Feb 11 doi: 10.1111/pde.13749. PMID: 30746752
Lichenoid dermatoses in hospitals in Lomé, Togo: 959 cases.
Teclessou JN, Akakpo AS, Saka B, Mouhari-Toure A, Kombate K, Pitche P
Med Sante Trop 2018 Aug 1;28(3):261-264. doi: 10.1684/mst.2018.0805. PMID: 30105987
Lichen planus and other lichenoid dermatoses: Kids are not just little people.
Payette MJ, Weston G, Humphrey S, Yu J, Holland KE
Clin Dermatol 2015 Nov-Dec;33(6):631-43. Epub 2015 Sep 12 doi: 10.1016/j.clindermatol.2015.09.006. PMID: 26686015
Lichenoid tissue reaction.
Panja SK, Banerjee PK
Indian J Dermatol 1989 Sep;34(3):47-53. PMID: 2632377
Papulosquamous diseases: a review.
Fox BJ, Odom RB
J Am Acad Dermatol 1985 Apr;12(4):597-624. doi: 10.1016/s0190-9622(85)70084-9. PMID: 3157710

Diagnosis

Lichen Nitidus.
Jordan AS, Green MC, Sulit DJ
J Am Osteopath Assoc 2019 Oct 1;119(10):704. doi: 10.7556/jaoa.2019.119. PMID: 31566698
Lichen nitidus.
Agharbi FZ
Pan Afr Med J 2019;32:39. Epub 2019 Jan 22 doi: 10.11604/pamj.2019.32.39.13564. PMID: 31143344Free PMC Article
Noninfectious Penile Lesions.
Teichman JMH, Mannas M, Elston DM
Am Fam Physician 2018 Jan 15;97(2):102-110. PMID: 29365226
Lichen planus and other lichenoid dermatoses: Kids are not just little people.
Payette MJ, Weston G, Humphrey S, Yu J, Holland KE
Clin Dermatol 2015 Nov-Dec;33(6):631-43. Epub 2015 Sep 12 doi: 10.1016/j.clindermatol.2015.09.006. PMID: 26686015
Noninfectious penile lesions.
Teichman JM, Sea J, Thompson IM, Elston DM
Am Fam Physician 2010 Jan 15;81(2):167-74. PMID: 20082512

Therapy

Facial lichen nitidus actinicus.
Dar NR, Rao SU
Australas J Dermatol 2012 May;53(2):e16-7. Epub 2010 Dec 30 doi: 10.1111/j.1440-0960.2010.00716.x. PMID: 22571575
Generalized lichen nitidus.
Al-Mutairi N, Hassanein A, Nour-Eldin O, Arun J
Pediatr Dermatol 2005 Mar-Apr;22(2):158-60. doi: 10.1111/j.1525-1470.2005.22215.x. PMID: 15804308
Lichenoid eruptions in children.
Tilly JJ, Drolet BA, Esterly NB
J Am Acad Dermatol 2004 Oct;51(4):606-24. doi: 10.1016/j.jaad.2003.12.012. PMID: 15389198
Generalized lichen nitidus.
Chen W, Schramm M, Zouboulis CC
J Am Acad Dermatol 1997 Apr;36(4):630-1. doi: 10.1016/s0190-9622(97)70255-x. PMID: 9092753
Coexistence of atopic dermatitis and lichen nitidus in three patients.
Lestringant GG, Piletta P, Feldmann R, Galadari I, Frossard PM, Saurat JH
Dermatology 1996;192(2):171-3. doi: 10.1159/000246351. PMID: 8829506

Prognosis

Perforating lichen nitidus.
Zussman J, Smart CN
Am J Dermatopathol 2015 May;37(5):406-8. doi: 10.1097/DAD.0000000000000211. PMID: 25803725
Antigen mimicry followed by epitope spreading: a pathogenetic trigger for the clinical morphology of lichen planus and its transition to Graham Lassueur Piccardi Little Syndrome and keratosis lichenoides chronica - Medical hypotheses or reality?
Tchernev G, Nenoff P
An Bras Dermatol 2009 Nov-Dec;84(6):682-8. doi: 10.1590/s0365-05962009000600019. PMID: 20191185
Generalized purpuric lichen nitidus. Report of a case and review of the literature.
Rallis E, Verros C, Moussatou V, Sambaziotis D, Papadakis P
Dermatol Online J 2007 May 1;13(2):5. PMID: 17498424
Lichenoid eruptions in children.
Tilly JJ, Drolet BA, Esterly NB
J Am Acad Dermatol 2004 Oct;51(4):606-24. doi: 10.1016/j.jaad.2003.12.012. PMID: 15389198
Perforating lichen nitidus.
Bardach H
J Cutan Pathol 1981 Apr;8(2):111-6. doi: 10.1111/j.1600-0560.1981.tb00994.x. PMID: 7276287

Clinical prediction guides

In vivo reflectance confocal microscopy for evaluating seborrheic keratosis, verruca plana, syringoma and lichen nitidus.
Dai H, Jiang HY, Xu AE
Skin Res Technol 2021 Mar;27(2):272-276. Epub 2020 Nov 11 doi: 10.1111/srt.12934. PMID: 33174647
Noninfectious Penile Lesions.
Teichman JMH, Mannas M, Elston DM
Am Fam Physician 2018 Jan 15;97(2):102-110. PMID: 29365226
Perforating lichen nitidus.
Zussman J, Smart CN
Am J Dermatopathol 2015 May;37(5):406-8. doi: 10.1097/DAD.0000000000000211. PMID: 25803725
Noninfectious penile lesions.
Teichman JM, Sea J, Thompson IM, Elston DM
Am Fam Physician 2010 Jan 15;81(2):167-74. PMID: 20082512
Lichenoid eruptions in children.
Tilly JJ, Drolet BA, Esterly NB
J Am Acad Dermatol 2004 Oct;51(4):606-24. doi: 10.1016/j.jaad.2003.12.012. PMID: 15389198

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