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Neuroectodermal neoplasm

MedGen UID:
60072
•Concept ID:
C0206093
•
Neoplastic Process
Synonyms: Neuroectodermal Tumor; Neuroectodermal Tumors; Tumor, Neuroectodermal; Tumors, Neuroectodermal
SNOMED CT: Neuroectodermal tumor (73676002); Neuroectodermal tumor (253096008)
 
HPO: HP:0030061

Definition

A neoplasm arising in the neuroectoderm, the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems, including some glial cells. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeuroectodermal neoplasm

Professional guidelines

PubMed

MTH-68/H oncolytic viral treatment in human high-grade gliomas.
Csatary LK, Gosztonyi G, Szeberenyi J, Fabian Z, Liszka V, Bodey B, Csatary CM
J Neurooncol 2004 Mar-Apr;67(1-2):83-93. doi: 10.1023/b:neon.0000021735.85511.05. PMID: 15072452

Recent clinical studies

Etiology

DNA methylation-based reclassification of olfactory neuroblastoma.
Capper D, Engel NW, Stichel D, Lechner M, Glöss S, Schmid S, Koelsche C, Schrimpf D, Niesen J, Wefers AK, Jones DTW, Sill M, Weigert O, Ligon KL, Olar A, Koch A, Forster M, Moran S, Tirado OM, Sáinz-Jaspeado M, Mora J, Esteller M, Alonso J, Del Muro XG, Paulus W, Felsberg J, Reifenberger G, Glatzel M, Frank S, Monoranu CM, Lund VJ, von Deimling A, Pfister S, Buslei R, Ribbat-Idel J, Perner S, Gudziol V, Meinhardt M, Schüller U
Acta Neuropathol 2018 Aug;136(2):255-271. Epub 2018 May 5 doi: 10.1007/s00401-018-1854-7. PMID: 29730775
Neuroendocrine neoplasms of the head and neck and olfactory neuroblastoma. Diagnosis and classification.
Uccella S, Ottini G, Facco C, Maragliano R, Asioli S, Sessa F, La Rosa S
Pathologica 2017 Mar;109(1):14-30. PMID: 28635990
Diffuse anterior retinoblastoma without retinal involvement.
Longmuir SQ, Syed NA, Boldt HC
Ophthalmology 2010 Oct;117(10):2034-8. Epub 2010 Jul 21 doi: 10.1016/j.ophtha.2010.02.010. PMID: 20663567
Neoplastic meningitis as the presentation of occult primitive neuroectodermal tumors.
Jennings MT, Slatkin N, D'Angelo M, Ketonen L, Johnson MD, Rosenblum M, Creasy J, Tulipan N, Walker R
J Child Neurol 1993 Oct;8(4):306-12. doi: 10.1177/088307389300800403. PMID: 8228025

Diagnosis

Neuroblastoma of the Lumbar Spine.
Hung B, Pennington Z, Sciubba DM
World Neurosurg 2021 Jul;151:2-4. Epub 2021 Apr 2 doi: 10.1016/j.wneu.2021.03.137. PMID: 33819706
Central nervous system ganglioneuroblastoma harboring MYO5A-NTRK3 fusion.
Ito J, Nakano Y, Shima H, Miwa T, Kogure Y, Isshiki K, Yamazaki F, Oishi Y, Morimoto Y, Kataoka K, Okita H, Hirato J, Ichimura K, Shimada H
Brain Tumor Pathol 2020 Jul;37(3):105-110. Epub 2020 Jun 18 doi: 10.1007/s10014-020-00371-1. PMID: 32556925
DNA methylation-based reclassification of olfactory neuroblastoma.
Capper D, Engel NW, Stichel D, Lechner M, Glöss S, Schmid S, Koelsche C, Schrimpf D, Niesen J, Wefers AK, Jones DTW, Sill M, Weigert O, Ligon KL, Olar A, Koch A, Forster M, Moran S, Tirado OM, Sáinz-Jaspeado M, Mora J, Esteller M, Alonso J, Del Muro XG, Paulus W, Felsberg J, Reifenberger G, Glatzel M, Frank S, Monoranu CM, Lund VJ, von Deimling A, Pfister S, Buslei R, Ribbat-Idel J, Perner S, Gudziol V, Meinhardt M, Schüller U
Acta Neuropathol 2018 Aug;136(2):255-271. Epub 2018 May 5 doi: 10.1007/s00401-018-1854-7. PMID: 29730775
Neuroendocrine neoplasms of the head and neck and olfactory neuroblastoma. Diagnosis and classification.
Uccella S, Ottini G, Facco C, Maragliano R, Asioli S, Sessa F, La Rosa S
Pathologica 2017 Mar;109(1):14-30. PMID: 28635990
Neoplastic meningitis as the presentation of occult primitive neuroectodermal tumors.
Jennings MT, Slatkin N, D'Angelo M, Ketonen L, Johnson MD, Rosenblum M, Creasy J, Tulipan N, Walker R
J Child Neurol 1993 Oct;8(4):306-12. doi: 10.1177/088307389300800403. PMID: 8228025

Therapy

Diffuse anterior retinoblastoma without retinal involvement.
Longmuir SQ, Syed NA, Boldt HC
Ophthalmology 2010 Oct;117(10):2034-8. Epub 2010 Jul 21 doi: 10.1016/j.ophtha.2010.02.010. PMID: 20663567
MTH-68/H oncolytic viral treatment in human high-grade gliomas.
Csatary LK, Gosztonyi G, Szeberenyi J, Fabian Z, Liszka V, Bodey B, Csatary CM
J Neurooncol 2004 Mar-Apr;67(1-2):83-93. doi: 10.1023/b:neon.0000021735.85511.05. PMID: 15072452

Prognosis

Advanced olfactory neuroblastoma in a teenager: a clinical case and short review of literature.
Pacino GA, Salvatore C, Antonino M, Cristina DMM, Piero P, Giacomo S
Childs Nerv Syst 2020 Mar;36(3):485-489. Epub 2020 Jan 27 doi: 10.1007/s00381-020-04514-9. PMID: 31989207
Medullomyoblastoma: a case report and literature review of a rare tumor entity.
Smolle E, Al-Qubati S, Stefanits H, Haberler C, Kleinert R, Haybaeck J
Anticancer Res 2012 Nov;32(11):4939-44. PMID: 23155263
MTH-68/H oncolytic viral treatment in human high-grade gliomas.
Csatary LK, Gosztonyi G, Szeberenyi J, Fabian Z, Liszka V, Bodey B, Csatary CM
J Neurooncol 2004 Mar-Apr;67(1-2):83-93. doi: 10.1023/b:neon.0000021735.85511.05. PMID: 15072452
Peripheral neuroectodermal tumor of the chest (Askin tumor) as secondary neoplasm after Hodgkin's disease: a case report.
Anselmo AP, Cartoni C, Pacchiarotti A, Pescarmona E, Cafolla A, Rendina E, Mandelli F
Ann Hematol 1994 Jun;68(6):311-3. doi: 10.1007/BF01695039. PMID: 8038238

Clinical prediction guides

DICER1-associated malignancies mimicking germ cell neoplasms: Report of two cases and review of the literature.
Rossi S, Barresi S, Stracuzzi A, Lopez-Nunez O, Chiaravalli S, Ferrari A, Ciolfi A, Maria Milano G, Giovannoni I, Tartaglia M, Miele E, Alaggio R
Pathol Res Pract 2021 Sep;225:153553. Epub 2021 Jul 16 doi: 10.1016/j.prp.2021.153553. PMID: 34329835

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