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Diabetic foot

MedGen UID:
60092
Concept ID:
C0206172
Disease or Syndrome
Synonyms: Diabetic Feet; Diabetic Foot; Feet, Diabetic; Foot, Diabetic
SNOMED CT: Diabetic foot (280137006)

Definition

Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiabetic foot

Professional guidelines

PubMed

Cloete L
Nurs Stand 2022 Jan 5;37(1):61-66. Epub 2021 Oct 28 doi: 10.7748/ns.2021.e11709. PMID: 34708622
Bowers S, Franco E
Am Fam Physician 2020 Feb 1;101(3):159-166. PMID: 32003952
Bandyk DF
Semin Vasc Surg 2018 Jun-Dec;31(2-4):43-48. Epub 2019 Feb 6 doi: 10.1053/j.semvascsurg.2019.02.001. PMID: 30876640

Recent clinical studies

Etiology

Reardon R, Simring D, Kim B, Mortensen J, Williams D, Leslie A
Aust J Gen Pract 2020 May;49(5):250-255. doi: 10.31128/AJGP-11-19-5161. PMID: 32416652
Schaper NC, van Netten JJ, Apelqvist J, Bus SA, Hinchliffe RJ, Lipsky BA; IWGDF Editorial Board
Diabetes Metab Res Rev 2020 Mar;36 Suppl 1:e3266. doi: 10.1002/dmrr.3266. PMID: 32176447
Bandyk DF
Semin Vasc Surg 2018 Jun-Dec;31(2-4):43-48. Epub 2019 Feb 6 doi: 10.1053/j.semvascsurg.2019.02.001. PMID: 30876640
Armstrong DG, Boulton AJM, Bus SA
N Engl J Med 2017 Jun 15;376(24):2367-2375. doi: 10.1056/NEJMra1615439. PMID: 28614678
Lim JZ, Ng NS, Thomas C
J R Soc Med 2017 Mar;110(3):104-109. Epub 2017 Jan 24 doi: 10.1177/0141076816688346. PMID: 28116957Free PMC Article

Diagnosis

Reardon R, Simring D, Kim B, Mortensen J, Williams D, Leslie A
Aust J Gen Pract 2020 May;49(5):250-255. doi: 10.31128/AJGP-11-19-5161. PMID: 32416652
Bandyk DF
Semin Vasc Surg 2018 Jun-Dec;31(2-4):43-48. Epub 2019 Feb 6 doi: 10.1053/j.semvascsurg.2019.02.001. PMID: 30876640
Mishra SC, Chhatbar KC, Kashikar A, Mehndiratta A
BMJ 2017 Nov 16;359:j5064. doi: 10.1136/bmj.j5064. PMID: 29146579Free PMC Article
Lim JZ, Ng NS, Thomas C
J R Soc Med 2017 Mar;110(3):104-109. Epub 2017 Jan 24 doi: 10.1177/0141076816688346. PMID: 28116957Free PMC Article
Volmer-Thole M, Lobmann R
Int J Mol Sci 2016 Jun 10;17(6) doi: 10.3390/ijms17060917. PMID: 27294922Free PMC Article

Therapy

Tay JS, Kim YJ
Medicine (Baltimore) 2021 Dec 10;100(49):e28173. doi: 10.1097/MD.0000000000028173. PMID: 34889293Free PMC Article
Gariani K, Pham TT, Kressmann B, Jornayvaz FR, Gastaldi G, Stafylakis D, Philippe J, Lipsky BA, Uçkay L
Clin Infect Dis 2021 Oct 5;73(7):e1539-e1545. doi: 10.1093/cid/ciaa1758. PMID: 33242083
Seidel D, Storck M, Lawall H, Wozniak G, Mauckner P, Hochlenert D, Wetzel-Roth W, Sondern K, Hahn M, Rothenaicher G, Krönert T, Zink K, Neugebauer E
BMJ Open 2020 Mar 24;10(3):e026345. doi: 10.1136/bmjopen-2018-026345. PMID: 32209619Free PMC Article
Kranke P, Bennett MH, Martyn-St James M, Schnabel A, Debus SE, Weibel S
Cochrane Database Syst Rev 2015 Jun 24;2015(6):CD004123. doi: 10.1002/14651858.CD004123.pub4. PMID: 26106870Free PMC Article
Jull AB, Cullum N, Dumville JC, Westby MJ, Deshpande S, Walker N
Cochrane Database Syst Rev 2015 Mar 6;2015(3):CD005083. doi: 10.1002/14651858.CD005083.pub4. PMID: 25742878Free PMC Article

Prognosis

Zhang C, Huang L, Wang X, Zhou X, Zhang X, Li L, Wu J, Kou M, Cai C, Lian Q, Zhou X
Stem Cell Res Ther 2022 Sep 5;13(1):451. doi: 10.1186/s13287-022-03143-0. PMID: 36064461Free PMC Article
Seidel D, Storck M, Lawall H, Wozniak G, Mauckner P, Hochlenert D, Wetzel-Roth W, Sondern K, Hahn M, Rothenaicher G, Krönert T, Zink K, Neugebauer E
BMJ Open 2020 Mar 24;10(3):e026345. doi: 10.1136/bmjopen-2018-026345. PMID: 32209619Free PMC Article
Pourkazemi A, Ghanbari A, Khojamli M, Balo H, Hemmati H, Jafaryparvar Z, Motamed B
BMC Endocr Disord 2020 Mar 20;20(1):40. doi: 10.1186/s12902-020-0512-y. PMID: 32192488Free PMC Article
Hajhosseini B, Longaker MT, Gurtner GC
Ann Surg 2020 Apr;271(4):671-679. doi: 10.1097/SLA.0000000000003567. PMID: 31460882
Armstrong DG, Boulton AJM, Bus SA
N Engl J Med 2017 Jun 15;376(24):2367-2375. doi: 10.1056/NEJMra1615439. PMID: 28614678

Clinical prediction guides

Wang Y, Shao T, Wang J, Huang X, Deng X, Cao Y, Zhou M, Zhao C
Biomed Pharmacother 2021 Jan;133:110991. Epub 2020 Nov 20 doi: 10.1016/j.biopha.2020.110991. PMID: 33227713
Pourkazemi A, Ghanbari A, Khojamli M, Balo H, Hemmati H, Jafaryparvar Z, Motamed B
BMC Endocr Disord 2020 Mar 20;20(1):40. doi: 10.1186/s12902-020-0512-y. PMID: 32192488Free PMC Article
Monteiro-Soares M, Boyko EJ, Jeffcoate W, Mills JL, Russell D, Morbach S, Game F
Diabetes Metab Res Rev 2020 Mar;36 Suppl 1:e3272. doi: 10.1002/dmrr.3272. PMID: 32176449
Bandyk DF
Semin Vasc Surg 2018 Jun-Dec;31(2-4):43-48. Epub 2019 Feb 6 doi: 10.1053/j.semvascsurg.2019.02.001. PMID: 30876640
Brocco E, Ninkovic S, Marin M, Whisstock C, Bruseghin M, Boschetti G, Viti R, Forlini W, Volpe A
J Cardiovasc Surg (Torino) 2018 Oct;59(5):670-684. Epub 2018 May 29 doi: 10.23736/S0021-9509.18.10606-9. PMID: 29808982

Recent systematic reviews

Zhang Z, Zhang W, Xu Y, Liu D
Asian J Surg 2022 Jan;45(1):68-78. Epub 2021 Aug 8 doi: 10.1016/j.asjsur.2021.07.047. PMID: 34376365
Pérez-Panero AJ, Ruiz-Muñoz M, Cuesta-Vargas AI, Gónzalez-Sánchez M
Medicine (Baltimore) 2019 Aug;98(35):e16877. doi: 10.1097/MD.0000000000016877. PMID: 31464916Free PMC Article
Matos M, Mendes R, Silva AB, Sousa N
Diabetes Res Clin Pract 2018 May;139:81-90. Epub 2018 Feb 23 doi: 10.1016/j.diabres.2018.02.020. PMID: 29477503
Zhang P, Lu J, Jing Y, Tang S, Zhu D, Bi Y
Ann Med 2017 Mar;49(2):106-116. Epub 2016 Nov 3 doi: 10.1080/07853890.2016.1231932. PMID: 27585063
van Netten JJ, Price PE, Lavery LA, Monteiro-Soares M, Rasmussen A, Jubiz Y, Bus SA; International Working Group on the Diabetic Foot
Diabetes Metab Res Rev 2016 Jan;32 Suppl 1:84-98. doi: 10.1002/dmrr.2701. PMID: 26340966

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