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Prolonged ST segment

MedGen UID:
606922
•Concept ID:
C0429030
•
Finding
Synonym: Prolonged ST Segment by ECG Finding
SNOMED CT: Prolonged ST segment (56260006)

Definition

An electrocardiographic finding of a prolonged ST segment, resulting in an increased QT interval, without lengthening of the T wave duration; this may be observed in hypocalcemia. (CDISC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProlonged ST segment

Professional guidelines

PubMed

Genotype Positive Long QT Syndrome in Patients With Coexisting Congenital Heart Disease.
Ebrahim MA, Williams MR, Shepard S, Perry JC
Am J Cardiol 2017 Jul 15;120(2):256-261. Epub 2017 Apr 27 doi: 10.1016/j.amjcard.2017.04.018. PMID: 28532774

Recent clinical studies

Etiology

Secondary rotational atherectomy is associated with reduced occurrence of prolonged ST-segment elevation following ablation.
Kanda D, Takumi T, Arikawa R, Anzaki K, Sonoda T, Ohmure K, Fukumoto D, Tokushige A, Ohishi M
Intern Emerg Med 2023 Oct;18(7):1995-2002. Epub 2023 Aug 11 doi: 10.1007/s11739-023-03385-7. PMID: 37566359Free PMC Article
Prolonged ST segment and T-wave alternans with torsade de pointes secondary to hypocalcemia due to hypoparathyroidism: A case report.
Liu J, Hou H, Xu H, Chen Y, Su X
Ann Noninvasive Electrocardiol 2022 Jul;27(4):e12939. Epub 2022 Feb 11 doi: 10.1111/anec.12939. PMID: 35146844Free PMC Article
Coping and Cardiac Troponin T - A Risk for Hypertension and Sub-Clinical ECG Left Ventricular Hypertrophy: The SABPA Study.
Myburgh CE, Malan L, Wentzel A, Scheepers JW, Malan NT
Heart Lung Circ 2019 Jun;28(6):908-916. Epub 2018 May 31 doi: 10.1016/j.hlc.2018.05.101. PMID: 29895484
Genotype Positive Long QT Syndrome in Patients With Coexisting Congenital Heart Disease.
Ebrahim MA, Williams MR, Shepard S, Perry JC
Am J Cardiol 2017 Jul 15;120(2):256-261. Epub 2017 Apr 27 doi: 10.1016/j.amjcard.2017.04.018. PMID: 28532774
Prolonged ST segment depression after stress testing: does it really identify more severe disease?
Desai MY, De la Peña-Almaguer E, Mannting F
Int J Cardiol 2003 Jan;87(1):59-66. doi: 10.1016/s0167-5273(02)00206-1. PMID: 12468055

Diagnosis

Prolonged ST segment and T-wave alternans with torsade de pointes secondary to hypocalcemia due to hypoparathyroidism: A case report.
Liu J, Hou H, Xu H, Chen Y, Su X
Ann Noninvasive Electrocardiol 2022 Jul;27(4):e12939. Epub 2022 Feb 11 doi: 10.1111/anec.12939. PMID: 35146844Free PMC Article
Coping and Cardiac Troponin T - A Risk for Hypertension and Sub-Clinical ECG Left Ventricular Hypertrophy: The SABPA Study.
Myburgh CE, Malan L, Wentzel A, Scheepers JW, Malan NT
Heart Lung Circ 2019 Jun;28(6):908-916. Epub 2018 May 31 doi: 10.1016/j.hlc.2018.05.101. PMID: 29895484
Genotype Positive Long QT Syndrome in Patients With Coexisting Congenital Heart Disease.
Ebrahim MA, Williams MR, Shepard S, Perry JC
Am J Cardiol 2017 Jul 15;120(2):256-261. Epub 2017 Apr 27 doi: 10.1016/j.amjcard.2017.04.018. PMID: 28532774
Electrolyte disorders and arrhythmogenesis.
El-Sherif N, Turitto G
Cardiol J 2011;18(3):233-45. PMID: 21660912
Pronounced and prolonged ST segment elevation: a pathognomonic sign of tumor invasion of the heart.
Hartman RB, Clark PI, Schulman P
Arch Intern Med 1982 Oct;142(10):1917-9. PMID: 7125773

Therapy

Prolonged ST segment and T-wave alternans with torsade de pointes secondary to hypocalcemia due to hypoparathyroidism: A case report.
Liu J, Hou H, Xu H, Chen Y, Su X
Ann Noninvasive Electrocardiol 2022 Jul;27(4):e12939. Epub 2022 Feb 11 doi: 10.1111/anec.12939. PMID: 35146844Free PMC Article
Coping and Cardiac Troponin T - A Risk for Hypertension and Sub-Clinical ECG Left Ventricular Hypertrophy: The SABPA Study.
Myburgh CE, Malan L, Wentzel A, Scheepers JW, Malan NT
Heart Lung Circ 2019 Jun;28(6):908-916. Epub 2018 May 31 doi: 10.1016/j.hlc.2018.05.101. PMID: 29895484
Postoperative myocardial ischemia: etiology of cardiac morbidity or manifestation of underlying disease?
Fleisher LA, Nelson AH, Rosenbaum SH
J Clin Anesth 1995 Mar;7(2):97-102. doi: 10.1016/0952-8180(94)00030-8. PMID: 7598933

Prognosis

Genotype Positive Long QT Syndrome in Patients With Coexisting Congenital Heart Disease.
Ebrahim MA, Williams MR, Shepard S, Perry JC
Am J Cardiol 2017 Jul 15;120(2):256-261. Epub 2017 Apr 27 doi: 10.1016/j.amjcard.2017.04.018. PMID: 28532774
Tako Tsubo cardiomyopathy in a patient with multiple trauma.
Vergez M, Pirracchio R, Mateo J, Payen D, Cholley B
Resuscitation 2009 Sep;80(9):1074-7. Epub 2009 Jul 5 doi: 10.1016/j.resuscitation.2009.05.021. PMID: 19581037
Prolonged ST segment depression after stress testing: does it really identify more severe disease?
Desai MY, De la Peña-Almaguer E, Mannting F
Int J Cardiol 2003 Jan;87(1):59-66. doi: 10.1016/s0167-5273(02)00206-1. PMID: 12468055

Clinical prediction guides

Coping and Cardiac Troponin T - A Risk for Hypertension and Sub-Clinical ECG Left Ventricular Hypertrophy: The SABPA Study.
Myburgh CE, Malan L, Wentzel A, Scheepers JW, Malan NT
Heart Lung Circ 2019 Jun;28(6):908-916. Epub 2018 May 31 doi: 10.1016/j.hlc.2018.05.101. PMID: 29895484
Prolonged ST segment depression after stress testing: does it really identify more severe disease?
Desai MY, De la Peña-Almaguer E, Mannting F
Int J Cardiol 2003 Jan;87(1):59-66. doi: 10.1016/s0167-5273(02)00206-1. PMID: 12468055
Postoperative myocardial ischemia: etiology of cardiac morbidity or manifestation of underlying disease?
Fleisher LA, Nelson AH, Rosenbaum SH
J Clin Anesth 1995 Mar;7(2):97-102. doi: 10.1016/0952-8180(94)00030-8. PMID: 7598933
Detection and management of the asymptomatic patient with coronary artery disease.
Conti CR
Adv Cardiol 1980;27:181-90. doi: 10.1159/000383984. PMID: 7446285

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