Campi I, Covelli D, Moran C, Fugazzola L, Cacciatore C, Orlandi F, Gallone G, Chatterjee K, Beck-Peccoz P, Persani L
Front Endocrinol (Lausanne) 2020;11:432. Epub 2020 Jul 7 doi: 10.3389/fendo.2020.00432. PMID: 32733382 Free PMC Article

Occurrence and management of an aberrant free T4 in combination with a normal TSH.

van Veggel KM, Rondeel JM, Anten S
Neth J Med 2018 Sep;76(7):314-321. PMID: 30220656

Neonatal hypothyroidism: treatment and outcome.

Van Vliet G
Thyroid 1999 Jan;9(1):79-84. doi: 10.1089/thy.1999.9.79. PMID: 10037081

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Recent clinical studies

Etiology

Maternal Thyroid Dysfunction and Neuropsychological Development in Children.

Chen Y, Luo ZC, Zhang T, Fan P, Ma R, Zhang J, Ouyang F
J Clin Endocrinol Metab 2023 Jan 17;108(2):339-350. doi: 10.1210/clinem/dgac577. PMID: 36198069

Update on Neonatal Isolated Hyperthyrotropinemia: A Systematic Review.

Chiesa AE, Tellechea ML
Front Endocrinol (Lausanne) 2021;12:643307. Epub 2021 Aug 18 doi: 10.3389/fendo.2021.643307. PMID: 34484109 Free PMC Article

Familial Dysalbuminemic Hyperthyroxinemia (FDH), Albumin Gene Variant (R218S), and Risk of Miscarriages in Offspring.

Lai S, Gopalakrishnan G, Li J, Liu X, Chen Y, Wen Y, Zhang S, Huang B, Phornphutkul C, Liu S, Kuang J
Am J Med Sci 2020 Nov;360(5):566-574. Epub 2020 May 28 doi: 10.1016/j.amjms.2020.05.035. PMID: 32665066

Factors associated with moderate neonatal hyperthyrotropinemia.

Cortés-Castell E, Juste M, Palazón-Bru A, Goicoechea M, Gil-Guillén VF, Rizo-Baeza MM
PLoS One 2019;14(7):e0220040. Epub 2019 Jul 18 doi: 10.1371/journal.pone.0220040. PMID: 31318940 Free PMC Article

Propranolol-induced hyperthyroxinemia.

Mooradian A, Morley JE, Simon G, Shafer RB
Arch Intern Med 1983 Nov;143(11):2193-5. PMID: 6639243

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Diagnosis

Impaired Sensitivity to Thyroid Hormones Is Associated With Diabetes and Metabolic Syndrome.

Laclaustra M, Moreno-Franco B, Lou-Bonafonte JM, Mateo-Gallego R, Casasnovas JA, Guallar-Castillon P, Cenarro A, Civeira F
Diabetes Care 2019 Feb;42(2):303-310. Epub 2018 Dec 14 doi: 10.2337/dc18-1410. PMID: 30552134

Directional thyroid hormone distribution via the blood stream to target sites.

Janssen ST, Janssen OE
Mol Cell Endocrinol 2017 Dec 15;458:16-21. Epub 2017 Feb 28 doi: 10.1016/j.mce.2017.02.037. PMID: 28257828

Inherited defects of thyroxine-binding proteins.

Pappa T, Ferrara AM, Refetoff S
Best Pract Res Clin Endocrinol Metab 2015 Oct;29(5):735-47. Epub 2015 Sep 30 doi: 10.1016/j.beem.2015.09.002. PMID: 26522458 Free PMC Article

Propranolol-induced hyperthyroxinemia.

Mooradian A, Morley JE, Simon G, Shafer RB
Arch Intern Med 1983 Nov;143(11):2193-5. PMID: 6639243

Euthyroid hyperthyroxinemia.

Borst GC, Eil C, Burman KD
Ann Intern Med 1983 Mar;98(3):366-78. doi: 10.7326/0003-4819-98-3-366. PMID: 6187257

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Therapy

Radioiodine therapy for Graves' disease: case selection and restrictions recommended to patients in North America.

Wartofsky L
Thyroid 1997 Apr;7(2):213-6. doi: 10.1089/thy.1997.7.213. PMID: 9133687

Effects of thyroxine excess on peripheral organs.

Bartalena L, Pinchera A
Acta Med Austriaca 1994;21(2):60-5. PMID: 7998484

Thyroxine excess and pregnancy.

Lazarus JH
Acta Med Austriaca 1994;21(2):53-6. PMID: 7527990

Propranolol-induced hyperthyroxinemia.

Mooradian A, Morley JE, Simon G, Shafer RB
Arch Intern Med 1983 Nov;143(11):2193-5. PMID: 6639243

Euthyroid hyperthyroxinemia.

Borst GC, Eil C, Burman KD
Ann Intern Med 1983 Mar;98(3):366-78. doi: 10.7326/0003-4819-98-3-366. PMID: 6187257

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Prognosis

Update on Neonatal Isolated Hyperthyrotropinemia: A Systematic Review.

Chiesa AE, Tellechea ML
Front Endocrinol (Lausanne) 2021;12:643307. Epub 2021 Aug 18 doi: 10.3389/fendo.2021.643307. PMID: 34484109 Free PMC Article

Familial Dysalbuminemic Hyperthyroxinemia (FDH), Albumin Gene Variant (R218S), and Risk of Miscarriages in Offspring.

Impaired Sensitivity to Thyroid Hormones Is Associated With Diabetes and Metabolic Syndrome.

Hyperthyroxinemia at birth: a cause of idiopathic neonatal hyperbilirubinemia?

Ulanovsky I, Smolkin T, Almashanu S, Mashiach T, Makhoul IR
World J Pediatr 2018 Jun;14(3):247-253. Epub 2018 May 2 doi: 10.1007/s12519-017-0113-7. PMID: 29721843

The relationship between hyperthyrotropinemia and metabolic and cardiovascular risk factors in a large group of overweight and obese children and adolescents.

Radetti G, Grugni G, Lupi F, Marazzi N, Longhi S, Fanolla A, Sartorio A
J Endocrinol Invest 2017 Dec;40(12):1311-1319. Epub 2017 Jun 5 doi: 10.1007/s40618-017-0705-z. PMID: 28585021

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Clinical prediction guides

Maternal Thyroid Dysfunction and Neuropsychological Development in Children.

Chen Y, Luo ZC, Zhang T, Fan P, Ma R, Zhang J, Ouyang F
J Clin Endocrinol Metab 2023 Jan 17;108(2):339-350. doi: 10.1210/clinem/dgac577. PMID: 36198069

The relationship between hyperthyrotropinemia and metabolic and cardiovascular risk factors in a large group of overweight and obese children and adolescents.

Radetti G, Grugni G, Lupi F, Marazzi N, Longhi S, Fanolla A, Sartorio A
J Endocrinol Invest 2017 Dec;40(12):1311-1319. Epub 2017 Jun 5 doi: 10.1007/s40618-017-0705-z. PMID: 28585021

Effects of thyroxine excess on peripheral organs.

Bartalena L, Pinchera A
Acta Med Austriaca 1994;21(2):60-5. PMID: 7998484

Variations in thyroid hormone transport proteins and their clinical implications.

Bartalena L, Robbins J
Thyroid 1992 Fall;2(3):237-45. doi: 10.1089/thy.1992.2.237. PMID: 1422238

Propranolol-induced hyperthyroxinemia.

Mooradian A, Morley JE, Simon G, Shafer RB
Arch Intern Med 1983 Nov;143(11):2193-5. PMID: 6639243

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