U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Perioral dermatitis

MedGen UID:
75521
•Concept ID:
C0263449
•
Disease or Syndrome
Synonyms: Dermatitides, Perioral; Dermatitis, Perioral; Perioral Dermatitides; Perioral Dermatitis
SNOMED CT: Perioral dermatitis (238751002); POD - Perioral dermatitis (238751002)

Definition

A papular eruption of unknown etiology that progresses to residual papular erythema and scaling usually confined to the area of the mouth, and almost exclusively occurring in young women. It may also be localized or extend to involve the eyelids and adjacent glabella area of the forehead (periocular dermatitis). (Dorland, 28th ed) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPerioral dermatitis

Professional guidelines

PubMed

Perioral dermatitis: Diagnosis, proposed etiologies, and management.
Searle T, Ali FR, Al-Niaimi F
J Cosmet Dermatol 2021 Dec;20(12):3839-3848. Epub 2021 Mar 16 doi: 10.1111/jocd.14060. PMID: 33751778
Perioral dermatitis: a review of the condition with special attention to treatment options.
Tempark T, Shwayder TA
Am J Clin Dermatol 2014 Apr;15(2):101-13. doi: 10.1007/s40257-014-0067-7. PMID: 24623018
Perioral dermatitis.
Wollenberg A, Bieber T, Dirschka T, Luger T, Meurer M, Proksch E, Schön MP, Schwarz T, Thaçi D, Zuberbier T, Werfel T; German Society of Dermatology
J Dtsch Dermatol Ges 2011 May;9(5):422-7. Epub 2010 Oct 8 doi: 10.1111/j.1610-0387.2010.07329.x. PMID: 21040469

Recent clinical studies

Etiology

Investigation of the Prevalence of Demodex spp. in Dermatological Diseases.
Erdal B, Albayrak H
Turkiye Parazitol Derg 2022 Mar 1;46(1):54-59. doi: 10.4274/tpd.galenos.2021.93685. PMID: 35232707
Pharmacological interventions for periorificial (perioral) dermatitis in children and adults: a systematic review.
Gray NA, Tod B, Rohwer A, Fincham L, Visser WI, McCaul M
J Eur Acad Dermatol Venereol 2022 Mar;36(3):380-390. Epub 2021 Dec 2 doi: 10.1111/jdv.17817. PMID: 34779023
The "Maskne" microbiome - pathophysiology and therapeutics.
Teo WL
Int J Dermatol 2021 Jul;60(7):799-809. Epub 2021 Feb 12 doi: 10.1111/ijd.15425. PMID: 33576511Free PMC Article
Perioral dermatitis: a review of the condition with special attention to treatment options.
Tempark T, Shwayder TA
Am J Clin Dermatol 2014 Apr;15(2):101-13. doi: 10.1007/s40257-014-0067-7. PMID: 24623018
Perioral dermatitis.
Hogan DJ
Curr Probl Dermatol 1995;22:98-104. doi: 10.1159/000424239. PMID: 7587342

Diagnosis

Perioral dermatitis: Diagnosis, proposed etiologies, and management.
Searle T, Ali FR, Al-Niaimi F
J Cosmet Dermatol 2021 Dec;20(12):3839-3848. Epub 2021 Mar 16 doi: 10.1111/jocd.14060. PMID: 33751778
A Practical Approach to Recalcitrant Face and Neck Dermatitis in Atopic Dermatitis.
Jaros J, Hendricks AJ, Shi VY, Lio PA
Dermatitis 2020 May-Jun;31(3):169-177. doi: 10.1097/DER.0000000000000590. PMID: 32355092
Candidiasis: Red and White Manifestations in the Oral Cavity.
Hellstein JW, Marek CL
Head Neck Pathol 2019 Mar;13(1):25-32. Epub 2019 Jan 29 doi: 10.1007/s12105-019-01004-6. PMID: 30693459Free PMC Article
Perioral dermatitis: a review of the condition with special attention to treatment options.
Tempark T, Shwayder TA
Am J Clin Dermatol 2014 Apr;15(2):101-13. doi: 10.1007/s40257-014-0067-7. PMID: 24623018
Acneiform eruptions.
Dessinioti C, Antoniou C, Katsambas A
Clin Dermatol 2014 Jan-Feb;32(1):24-34. doi: 10.1016/j.clindermatol.2013.05.023. PMID: 24314375

Therapy

Perioral dermatitis: Diagnosis, proposed etiologies, and management.
Searle T, Ali FR, Al-Niaimi F
J Cosmet Dermatol 2021 Dec;20(12):3839-3848. Epub 2021 Mar 16 doi: 10.1111/jocd.14060. PMID: 33751778
A Practical Approach to Recalcitrant Face and Neck Dermatitis in Atopic Dermatitis.
Jaros J, Hendricks AJ, Shi VY, Lio PA
Dermatitis 2020 May-Jun;31(3):169-177. doi: 10.1097/DER.0000000000000590. PMID: 32355092
Perioral dermatitis: a review of the condition with special attention to treatment options.
Tempark T, Shwayder TA
Am J Clin Dermatol 2014 Apr;15(2):101-13. doi: 10.1007/s40257-014-0067-7. PMID: 24623018
Perioral dermatitis.
Lipozenčić J, Hadžavdić SL
Clin Dermatol 2014 Jan-Feb;32(1):125-30. doi: 10.1016/j.clindermatol.2013.05.034. PMID: 24314386
Adverse effects of topical glucocorticosteroids.
Hengge UR, Ruzicka T, Schwartz RA, Cork MJ
J Am Acad Dermatol 2006 Jan;54(1):1-15; quiz 16-8. doi: 10.1016/j.jaad.2005.01.010. PMID: 16384751

Prognosis

Recent Advances in Pharmacotherapeutic Paradigm of Mild to Recalcitrant Atopic Dermatitis.
Hussain Z, Sahudin S, Thu HE, Shuid AN, Bukhari SN, Kumolosasi E
Crit Rev Ther Drug Carrier Syst 2016;33(3):213-263. doi: 10.1615/CritRevTherDrugCarrierSyst.2016015219. PMID: 27910751
Inflammatory and glandular skin disease in pregnancy.
Yang CS, Teeple M, Muglia J, Robinson-Bostom L
Clin Dermatol 2016 May-Jun;34(3):335-43. Epub 2016 Feb 11 doi: 10.1016/j.clindermatol.2016.02.005. PMID: 27265071
Critical appraisal of reports on the treatment of perioral dermatitis.
Weber K, Thurmayr R
Dermatology 2005;210(4):300-7. doi: 10.1159/000084754. PMID: 15942216
Topical cosmetics and perioral dermatitis.
Dirschka T, Weber K, Tronnier H
J Dtsch Dermatol Ges 2004 Mar;2(3):194-9. doi: 10.1046/j.1439-0353.2004.04764.x. PMID: 16281636
Perioral dermatitis.
Hogan DJ
Curr Probl Dermatol 1995;22:98-104. doi: 10.1159/000424239. PMID: 7587342

Clinical prediction guides

Inflammatory and glandular skin disease in pregnancy.
Yang CS, Teeple M, Muglia J, Robinson-Bostom L
Clin Dermatol 2016 May-Jun;34(3):335-43. Epub 2016 Feb 11 doi: 10.1016/j.clindermatol.2016.02.005. PMID: 27265071
Human demodicosis: revisit and a proposed classification.
Chen W, Plewig G
Br J Dermatol 2014 Jun;170(6):1219-25. doi: 10.1111/bjd.12850. PMID: 24471456
Adverse effects of topical glucocorticosteroids.
Hengge UR, Ruzicka T, Schwartz RA, Cork MJ
J Am Acad Dermatol 2006 Jan;54(1):1-15; quiz 16-8. doi: 10.1016/j.jaad.2005.01.010. PMID: 16384751
Perioral dermatitis in children--clinical presentation, pathogenesis-related factors and response to topical metronidazole.
Boeck K, Abeck D, Werfel S, Ring J
Dermatology 1997;195(3):235-8. doi: 10.1159/000245950. PMID: 9407169
Childhood rosacea.
Drolet B, Paller AS
Pediatr Dermatol 1992 Mar;9(1):22-6. doi: 10.1111/j.1525-1470.1992.tb00320.x. PMID: 1533454

Recent systematic reviews

Pharmacological interventions for periorificial (perioral) dermatitis in children and adults: a systematic review.
Gray NA, Tod B, Rohwer A, Fincham L, Visser WI, McCaul M
J Eur Acad Dermatol Venereol 2022 Mar;36(3):380-390. Epub 2021 Dec 2 doi: 10.1111/jdv.17817. PMID: 34779023
Perioral dermatitis: Diagnosis, proposed etiologies, and management.
Searle T, Ali FR, Al-Niaimi F
J Cosmet Dermatol 2021 Dec;20(12):3839-3848. Epub 2021 Mar 16 doi: 10.1111/jocd.14060. PMID: 33751778

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...