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Chorea gravidarum

MedGen UID:
75545
Concept ID:
C0264746
Disease or Syndrome
Synonyms: Chorea Gravidarum; Chorea Gravidarums; Chorea, Pregnancy Induced; Chorea, Pregnancy-Induced; Choreas, Pregnancy-Induced; Choreoathetoses, Pregnancy-Associated; Choreoathetosis, Pregnancy Associated; Choreoathetosis, Pregnancy-Associated; Gravidarum, Chorea; Pregnancy-Associated Choreoathetoses; Pregnancy-Associated Choreoathetosis; Pregnancy-Induced Chorea; Pregnancy-Induced Choreas
SNOMED CT: Chorea gravidarum (25113000)
 
Monarch Initiative: MONDO:0001976

Definition

A rare movement disorder developed during pregnancy, characterized by involuntary jerky motion (chorea) and inability to maintain stable position of body parts (athetosis). rheumatic fever and collagen vascular disorders are frequently associated with this disease. Chorea may vary from mild to severe and occurs in approximately 1 per 2,000 to 3,000 pregnancies. (From Md Med J 1997 Sep;46(8):436-9) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChorea gravidarum

Professional guidelines

PubMed

Feinstein E, Walker R
Tremor Other Hyperkinet Mov (N Y) 2020 Jul 16;10:22. doi: 10.5334/tohm.351. PMID: 32775036Free PMC Article
Wild EJ, Tabrizi SJ
Pract Neurol 2007 Nov;7(6):360-73. doi: 10.1136/pn.2007.134585. PMID: 18024776

Recent clinical studies

Etiology

Bovenzi R, Conti M, Schirinzi T
Expert Opin Pharmacother 2023 May-Aug;24(11):1317-1329. Epub 2023 May 24 doi: 10.1080/14656566.2023.2216380. PMID: 37204415
Pandey S
J Assoc Physicians India 2013 Jul;61(7):471-4, 483. PMID: 24772751
Maia DP, Fonseca PG, Camargos ST, Pfannes C, Cunningham MC, Cardoso F
Parkinsonism Relat Disord 2012 Jun;18(5):458-61. Epub 2012 Jan 10 doi: 10.1016/j.parkreldis.2011.12.013. PMID: 22236583
Karageyim AY, Kars B, Dansuk R, Aygun E, Unal O, Turan MC
J Matern Fetal Neonatal Med 2002 Nov;12(5):353-4. doi: 10.1080/jmf.12.5.353.354. PMID: 12607770
Lubbe WF, Butler WS, Palmer SJ, Liggins GC
Br J Obstet Gynaecol 1984 Apr;91(4):357-63. doi: 10.1111/j.1471-0528.1984.tb05923.x. PMID: 6424702

Diagnosis

Ba F, Miyasaki JM
Handb Clin Neurol 2020;172:219-239. doi: 10.1016/B978-0-444-64240-0.00013-1. PMID: 32768090
Rengifo-Quintero LJ, Beltrán-Avendaño MA
Rev Colomb Obstet Ginecol 2019 Sep;70(3):189-194. doi: 10.18597/rcog.3251. PMID: 31738489
Pandey S
J Assoc Physicians India 2013 Jul;61(7):471-4, 483. PMID: 24772751
Robottom BJ, Weiner WJ
Handb Clin Neurol 2011;100:231-5. doi: 10.1016/B978-0-444-52014-2.00015-X. PMID: 21496582
Wild EJ, Tabrizi SJ
Pract Neurol 2007 Nov;7(6):360-73. doi: 10.1136/pn.2007.134585. PMID: 18024776

Therapy

Feinstein E, Walker R
Tremor Other Hyperkinet Mov (N Y) 2020 Jul 16;10:22. doi: 10.5334/tohm.351. PMID: 32775036Free PMC Article
Rengifo-Quintero LJ, Beltrán-Avendaño MA
Rev Colomb Obstet Ginecol 2019 Sep;70(3):189-194. doi: 10.18597/rcog.3251. PMID: 31738489
Wild EJ, Tabrizi SJ
Pract Neurol 2007 Nov;7(6):360-73. doi: 10.1136/pn.2007.134585. PMID: 18024776
Palanivelu LM
J Obstet Gynaecol 2007 Apr;27(3):310. doi: 10.1080/01443610701241134. PMID: 17464821
Lewis BV, Parsons M
Lancet 1966 Feb 5;1(7432):284-6. doi: 10.1016/s0140-6736(66)90638-6. PMID: 4158893

Prognosis

Bovenzi R, Conti M, Schirinzi T
Expert Opin Pharmacother 2023 May-Aug;24(11):1317-1329. Epub 2023 May 24 doi: 10.1080/14656566.2023.2216380. PMID: 37204415
Rengifo-Quintero LJ, Beltrán-Avendaño MA
Rev Colomb Obstet Ginecol 2019 Sep;70(3):189-194. doi: 10.18597/rcog.3251. PMID: 31738489
Pathania M, Lali BS, Yadav NK, Chaturvedi A
BMJ Case Rep 2013 Feb 15;2013 doi: 10.1136/bcr-2012-008234. PMID: 23417936Free PMC Article
Kim A, Choi CH, Han CH, Shin JC
J Perinatol 2009 Apr;29(4):317-9. doi: 10.1038/jp.2008.183. PMID: 19325553
Cardoso F
Arch Neurol 2002 May;59(5):868-70. doi: 10.1001/archneur.59.5.868. PMID: 12020275

Clinical prediction guides

Vale TC, Glass PG, Lees A, Cardoso F
Eur Neurol 2013;69(1):48-52. Epub 2012 Nov 3 doi: 10.1159/000343628. PMID: 23128056
Karageyim AY, Kars B, Dansuk R, Aygun E, Unal O, Turan MC
J Matern Fetal Neonatal Med 2002 Nov;12(5):353-4. doi: 10.1080/jmf.12.5.353.354. PMID: 12607770
Omdal R, Roalsø S
Acta Neurol Scand 1992 Aug;86(2):219-20. doi: 10.1111/j.1600-0404.1992.tb05070.x. PMID: 1414234
Ichikawa K, Kim RC, Givelber H, Collins GH
Arch Neurol 1980 Jul;37(7):429-32. doi: 10.1001/archneur.1980.00500560059007. PMID: 7387488

Recent systematic reviews

Feinstein E, Walker R
Tremor Other Hyperkinet Mov (N Y) 2020 Jul 16;10:22. doi: 10.5334/tohm.351. PMID: 32775036Free PMC Article

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