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Reading seizure

MedGen UID:
75817
•Concept ID:
C0278193
•
Disease or Syndrome
Synonyms: EPILEPSY, READING; Reading seizures; Reflex Epilepsy, Reading
SNOMED CT: Reading seizure (7689009); Reading epilepsy (7689009)
 
Monarch Initiative: MONDO:0007560
OMIM®: 132300
Orphanet: ORPHA166433

Definition

A rare reflex epilepsy characterized by reading-induced seizures which in most cases present with orofacial/jaw myoclonus possibly extending to the upper limbs but can also manifest as dyslexia or alexia and visual symptoms. In both variants secondary generalized tonic-clonic seizures may evolve if the stimulus is not interrupted. The disease typically begins in the second or third decade of life and may be inherited in an autosomal dominant pattern. It usually takes a benign course with little tendency to spontaneous seizures. [from ORDO]

Clinical features

From HPO
Seizure
MedGen UID:
20693
•Concept ID:
C0036572
•
Sign or Symptom
A seizure is an intermittent abnormality of nervous system physiology characterized by a transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain.
See: Feature record | Search on this feature
EEG abnormality
MedGen UID:
56235
•Concept ID:
C0151611
•
Finding
Abnormality observed by electroencephalogram (EEG), which is used to record of the brain's spontaneous electrical activity from multiple electrodes placed on the scalp.
See: Feature record | Search on this feature

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReading seizure
Follow this link to review classifications for Reading seizure in Orphanet.

Professional guidelines

PubMed

Management of epilepsy with eyelid myoclonia: Results of an international expert consensus panel.
Smith KM, Wirrell EC, Andrade DM, Choi H, Trenité DK, Jones H, Knupp KG, Mugar J, Nordli DR Jr, Riva A, Stern JM, Striano P, Thiele EA, Zawar I
Epilepsia 2023 Sep;64(9):2342-2350. Epub 2023 Jun 23 doi: 10.1111/epi.17682. PMID: 37326215
Progesterone and its derivatives for the treatment of catamenial epilepsy: A systematic review.
Nucera B, Rinaldi F, Dono F, Lanzone J, Evangelista G, Consoli S, Tappatà M, Narducci F, Troisi S, Trinka E, Brigo F
Seizure 2023 Jul;109:52-59. Epub 2023 May 5 doi: 10.1016/j.seizure.2023.05.004. PMID: 37229848
International League Against Epilepsy classification and definition of epilepsy syndromes with onset at a variable age: position statement by the ILAE Task Force on Nosology and Definitions.
Riney K, Bogacz A, Somerville E, Hirsch E, Nabbout R, Scheffer IE, Zuberi SM, Alsaadi T, Jain S, French J, Specchio N, Trinka E, Wiebe S, Auvin S, Cabral-Lim L, Naidoo A, Perucca E, Moshé SL, Wirrell EC, Tinuper P
Epilepsia 2022 Jun;63(6):1443-1474. Epub 2022 May 3 doi: 10.1111/epi.17240. PMID: 35503725

Recent clinical studies

Etiology

SUDEP counseling: Where do we stand?
Whitney R, Jones KC, Sharma S, RamachandranNair R
Epilepsia 2023 Jun;64(6):1424-1431. Epub 2023 Apr 21 doi: 10.1111/epi.17617. PMID: 37039574
Perampanel and pregnancy.
Vazquez B, Tomson T, Dobrinsky C, Schuck E, O'Brien TJ
Epilepsia 2021 Mar;62(3):698-708. doi: 10.1111/epi.16821. PMID: 33666943Free PMC Article
Redefining epilepsy.
Fisher RS
Curr Opin Neurol 2015 Apr;28(2):130-5. doi: 10.1097/WCO.0000000000000174. PMID: 25734953
ILAE official report: a practical clinical definition of epilepsy.
Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J Jr, Forsgren L, French JA, Glynn M, Hesdorffer DC, Lee BI, Mathern GW, Moshé SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S
Epilepsia 2014 Apr;55(4):475-82. Epub 2014 Apr 14 doi: 10.1111/epi.12550. PMID: 24730690
Syncope.
Moya-I-Mitjans Á, Rivas-Gándara N, Sarrias-Mercè A, Pérez-Rodón J, Roca-Luque I
Rev Esp Cardiol (Engl Ed) 2012 Aug;65(8):755-65. Epub 2012 Jul 3 doi: 10.1016/j.recesp.2012.03.005. PMID: 22763183

Diagnosis

SUDEP counseling: Where do we stand?
Whitney R, Jones KC, Sharma S, RamachandranNair R
Epilepsia 2023 Jun;64(6):1424-1431. Epub 2023 Apr 21 doi: 10.1111/epi.17617. PMID: 37039574
Sunflower syndrome: a poorly understood photosensitive epilepsy.
Geenen KR, Patel S, Thiele EA
Dev Med Child Neurol 2021 Mar;63(3):259-262. Epub 2020 Oct 31 doi: 10.1111/dmcn.14723. PMID: 33135153
Juvenile myoclonic epilepsy as a spectrum disorder: A focused review.
Baykan B, Wolf P
Seizure 2017 Jul;49:36-41. Epub 2017 May 18 doi: 10.1016/j.seizure.2017.05.011. PMID: 28544889
Redefining epilepsy.
Fisher RS
Curr Opin Neurol 2015 Apr;28(2):130-5. doi: 10.1097/WCO.0000000000000174. PMID: 25734953
ILAE official report: a practical clinical definition of epilepsy.
Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J Jr, Forsgren L, French JA, Glynn M, Hesdorffer DC, Lee BI, Mathern GW, Moshé SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S
Epilepsia 2014 Apr;55(4):475-82. Epub 2014 Apr 14 doi: 10.1111/epi.12550. PMID: 24730690

Therapy

International League Against Epilepsy classification and definition of epilepsy syndromes with onset at a variable age: position statement by the ILAE Task Force on Nosology and Definitions.
Riney K, Bogacz A, Somerville E, Hirsch E, Nabbout R, Scheffer IE, Zuberi SM, Alsaadi T, Jain S, French J, Specchio N, Trinka E, Wiebe S, Auvin S, Cabral-Lim L, Naidoo A, Perucca E, Moshé SL, Wirrell EC, Tinuper P
Epilepsia 2022 Jun;63(6):1443-1474. Epub 2022 May 3 doi: 10.1111/epi.17240. PMID: 35503725
Perampanel and pregnancy.
Vazquez B, Tomson T, Dobrinsky C, Schuck E, O'Brien TJ
Epilepsia 2021 Mar;62(3):698-708. doi: 10.1111/epi.16821. PMID: 33666943Free PMC Article
Sunflower syndrome: a poorly understood photosensitive epilepsy.
Geenen KR, Patel S, Thiele EA
Dev Med Child Neurol 2021 Mar;63(3):259-262. Epub 2020 Oct 31 doi: 10.1111/dmcn.14723. PMID: 33135153
Vagus Nerve Stimulation and the Cardiovascular System.
Capilupi MJ, Kerath SM, Becker LB
Cold Spring Harb Perspect Med 2020 Feb 3;10(2) doi: 10.1101/cshperspect.a034173. PMID: 31109966Free PMC Article
Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis.
Koopman FA, Chavan SS, Miljko S, Grazio S, Sokolovic S, Schuurman PR, Mehta AD, Levine YA, Faltys M, Zitnik R, Tracey KJ, Tak PP
Proc Natl Acad Sci U S A 2016 Jul 19;113(29):8284-9. Epub 2016 Jul 5 doi: 10.1073/pnas.1605635113. PMID: 27382171Free PMC Article

Prognosis

Predictors of hyperkinetic seizures.
Menghi V, Bisulli F, Cardinale F, Vignatelli L, Zenesini C, Mai R, Proserpio P, Francione S, Sartori I, Tinuper P, Nobili L
Epilepsy Behav 2022 Apr;129:108629. Epub 2022 Mar 7 doi: 10.1016/j.yebeh.2022.108629. PMID: 35272206
Perampanel and pregnancy.
Vazquez B, Tomson T, Dobrinsky C, Schuck E, O'Brien TJ
Epilepsia 2021 Mar;62(3):698-708. doi: 10.1111/epi.16821. PMID: 33666943Free PMC Article
Juvenile myoclonic epilepsy and sleep.
Xu L, Guo D, Liu YY, Qiao DD, Ye JY, Xue R
Epilepsy Behav 2018 Mar;80:326-330. Epub 2018 Jan 19 doi: 10.1016/j.yebeh.2017.11.008. PMID: 29358100
Juvenile myoclonic epilepsy as a spectrum disorder: A focused review.
Baykan B, Wolf P
Seizure 2017 Jul;49:36-41. Epub 2017 May 18 doi: 10.1016/j.seizure.2017.05.011. PMID: 28544889
Syncope.
Moya-I-Mitjans Á, Rivas-Gándara N, Sarrias-Mercè A, Pérez-Rodón J, Roca-Luque I
Rev Esp Cardiol (Engl Ed) 2012 Aug;65(8):755-65. Epub 2012 Jul 3 doi: 10.1016/j.recesp.2012.03.005. PMID: 22763183

Clinical prediction guides

Predictors of hyperkinetic seizures.
Menghi V, Bisulli F, Cardinale F, Vignatelli L, Zenesini C, Mai R, Proserpio P, Francione S, Sartori I, Tinuper P, Nobili L
Epilepsy Behav 2022 Apr;129:108629. Epub 2022 Mar 7 doi: 10.1016/j.yebeh.2022.108629. PMID: 35272206
Perampanel and pregnancy.
Vazquez B, Tomson T, Dobrinsky C, Schuck E, O'Brien TJ
Epilepsia 2021 Mar;62(3):698-708. doi: 10.1111/epi.16821. PMID: 33666943Free PMC Article
Clinical advances in photosensitive epilepsy.
Padmanaban V, Inati S, Ksendzovsky A, Zaghloul K
Brain Res 2019 Jan 15;1703:18-25. Epub 2018 Aug 1 doi: 10.1016/j.brainres.2018.07.025. PMID: 30076791
Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis.
Koopman FA, Chavan SS, Miljko S, Grazio S, Sokolovic S, Schuurman PR, Mehta AD, Levine YA, Faltys M, Zitnik R, Tracey KJ, Tak PP
Proc Natl Acad Sci U S A 2016 Jul 19;113(29):8284-9. Epub 2016 Jul 5 doi: 10.1073/pnas.1605635113. PMID: 27382171Free PMC Article
Fixation-off sensitivity.
Brigo F, Rossini F, Stefani A, Nardone R, Tezzon F, Fiaschi A, Manganotti P, Bongiovanni LG
Clin Neurophysiol 2013 Feb;124(2):221-7. Epub 2012 Aug 24 doi: 10.1016/j.clinph.2012.07.017. PMID: 22925838

Recent systematic reviews

Progesterone and its derivatives for the treatment of catamenial epilepsy: A systematic review.
Nucera B, Rinaldi F, Dono F, Lanzone J, Evangelista G, Consoli S, Tappatà M, Narducci F, Troisi S, Trinka E, Brigo F
Seizure 2023 Jul;109:52-59. Epub 2023 May 5 doi: 10.1016/j.seizure.2023.05.004. PMID: 37229848
Academic attainment following pediatric epilepsy surgery: A systematic review.
Sherlock C, Madigan C, Linehan C, Keenan L, Downes M
Epilepsy Behav 2022 Sep;134:108847. Epub 2022 Jul 29 doi: 10.1016/j.yebeh.2022.108847. PMID: 35914437
Epilepsy diagnosis based on one unprovoked seizure and ≥60% risk. A systematic review of the etiologies.
Vergara López S, Ramos-Jiménez C, Adrián de la Cruz Reyes L, Kevin Galindo Ruiz A, Armando Baigts Arriola L, Manuel Moncayo Olivares J, Gabriela Aguirre Galindo E, Fabricio Pérez Pedroza I, San-Juan D
Epilepsy Behav 2021 Dec;125:108392. Epub 2021 Nov 2 doi: 10.1016/j.yebeh.2021.108392. PMID: 34740089
Efficacy of antiepileptic drugs in autoimmune epilepsy: A systematic review.
Cabezudo-García P, Mena-Vázquez N, Villagrán-García M, Serrano-Castro PJ
Seizure 2018 Jul;59:72-76. Epub 2018 May 7 doi: 10.1016/j.seizure.2018.05.004. PMID: 29754014
Theory of Mind in Patients with Epilepsy: a Systematic Review and Meta-analysis.
Stewart E, Catroppa C, Lah S
Neuropsychol Rev 2016 Mar;26(1):3-24. Epub 2016 Jan 21 doi: 10.1007/s11065-015-9313-x. PMID: 26797753

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