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Localized Resectable Neuroblastoma

MedGen UID:
75855
•Concept ID:
C0278691
•
Neoplastic Process

Definition

Neuroblastoma that is confined to a specific site and is amenable to surgical removal. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Resectable Neuroblastoma

Professional guidelines

PubMed

Management of Neuroblastoma in Pediatric Patients.
Croteau N, Nuchtern J, LaQuaglia MP
Surg Oncol Clin N Am 2021 Apr;30(2):291-304. Epub 2021 Feb 10 doi: 10.1016/j.soc.2020.11.010. PMID: 33706901
The Clinical Management and Outcomes of Pelvic Neuroblastic Tumors.
Zobel M, Zamora A, Sura A, Wang L, Stein J, Marachelian A, Kim ES
J Surg Res 2020 May;249:8-12. Epub 2020 Jan 7 doi: 10.1016/j.jss.2019.12.009. PMID: 31918331
Neuroblastoma: clinical and biological approach to risk stratification and treatment.
Tolbert VP, Matthay KK
Cell Tissue Res 2018 May;372(2):195-209. Epub 2018 Mar 23 doi: 10.1007/s00441-018-2821-2. PMID: 29572647Free PMC Article

Recent clinical studies

Etiology

Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group.
Ambros IM, Tonini GP, Pötschger U, Gross N, Mosseri V, Beiske K, Berbegall AP, Bénard J, Bown N, Caron H, Combaret V, Couturier J, Defferrari R, Delattre O, Jeison M, Kogner P, Lunec J, Marques B, Martinsson T, Mazzocco K, Noguera R, Schleiermacher G, Valent A, Van Roy N, Villamon E, Janousek D, Pribill I, Glogova E, Attiyeh EF, Hogarty MD, Monclair TF, Holmes K, Valteau-Couanet D, Castel V, Tweddle DA, Park JR, Cohn S, Ladenstein R, Beck-Popovic M, De Bernardi B, Michon J, Pearson ADJ, Ambros PF
J Clin Oncol 2020 Nov 1;38(31):3685-3697. Epub 2020 Sep 9 doi: 10.1200/JCO.18.02132. PMID: 32903140Free PMC Article
Identification of novel prognostic markers in relapsing localized resectable neuroblastoma.
Parodi F, Passoni L, Massimo L, Luksch R, Gambini C, Rossi E, Zuffardi O, Pistoia V, Pezzolo A
OMICS 2011 Mar;15(3):113-21. Epub 2011 Feb 14 doi: 10.1089/omi.2010.0085. PMID: 21319993
Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.
Pezzolo A, Rossi E, Gimelli S, Parodi F, Negri F, Conte M, Pistorio A, Sementa A, Pistoia V, Zuffardi O, Gambini C
Neuro Oncol 2009 Apr;11(2):192-200. Epub 2008 Oct 15 doi: 10.1215/15228517-2008-086. PMID: 18923191Free PMC Article
Localized resectable neuroblastoma: results of the second study of the Italian Cooperative Group for Neuroblastoma.
De Bernardi B, Conte M, Mancini A, Donfrancesco A, Alvisi P, Tomà P, Casale F, Cordero di Montezemolo L, Cornelli PE, Carli M
J Clin Oncol 1995 Apr;13(4):884-93. doi: 10.1200/JCO.1995.13.4.884. PMID: 7707115
Localized neuroblastoma treated by surgery: a Pediatric Oncology Group Study.
Nitschke R, Smith EI, Shochat S, Altshuler G, Travers H, Shuster JJ, Hayes FA, Patterson R, McWilliams N
J Clin Oncol 1988 Aug;6(8):1271-9. doi: 10.1200/JCO.1988.6.8.1271. PMID: 3411339

Diagnosis

Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group.
Ambros IM, Tonini GP, Pötschger U, Gross N, Mosseri V, Beiske K, Berbegall AP, Bénard J, Bown N, Caron H, Combaret V, Couturier J, Defferrari R, Delattre O, Jeison M, Kogner P, Lunec J, Marques B, Martinsson T, Mazzocco K, Noguera R, Schleiermacher G, Valent A, Van Roy N, Villamon E, Janousek D, Pribill I, Glogova E, Attiyeh EF, Hogarty MD, Monclair TF, Holmes K, Valteau-Couanet D, Castel V, Tweddle DA, Park JR, Cohn S, Ladenstein R, Beck-Popovic M, De Bernardi B, Michon J, Pearson ADJ, Ambros PF
J Clin Oncol 2020 Nov 1;38(31):3685-3697. Epub 2020 Sep 9 doi: 10.1200/JCO.18.02132. PMID: 32903140Free PMC Article
Identification of novel prognostic markers in relapsing localized resectable neuroblastoma.
Parodi F, Passoni L, Massimo L, Luksch R, Gambini C, Rossi E, Zuffardi O, Pistoia V, Pezzolo A
OMICS 2011 Mar;15(3):113-21. Epub 2011 Feb 14 doi: 10.1089/omi.2010.0085. PMID: 21319993
Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.
Pezzolo A, Rossi E, Gimelli S, Parodi F, Negri F, Conte M, Pistorio A, Sementa A, Pistoia V, Zuffardi O, Gambini C
Neuro Oncol 2009 Apr;11(2):192-200. Epub 2008 Oct 15 doi: 10.1215/15228517-2008-086. PMID: 18923191Free PMC Article

Therapy

Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group.
Ambros IM, Tonini GP, Pötschger U, Gross N, Mosseri V, Beiske K, Berbegall AP, Bénard J, Bown N, Caron H, Combaret V, Couturier J, Defferrari R, Delattre O, Jeison M, Kogner P, Lunec J, Marques B, Martinsson T, Mazzocco K, Noguera R, Schleiermacher G, Valent A, Van Roy N, Villamon E, Janousek D, Pribill I, Glogova E, Attiyeh EF, Hogarty MD, Monclair TF, Holmes K, Valteau-Couanet D, Castel V, Tweddle DA, Park JR, Cohn S, Ladenstein R, Beck-Popovic M, De Bernardi B, Michon J, Pearson ADJ, Ambros PF
J Clin Oncol 2020 Nov 1;38(31):3685-3697. Epub 2020 Sep 9 doi: 10.1200/JCO.18.02132. PMID: 32903140Free PMC Article
Localized resectable neuroblastoma: results of the second study of the Italian Cooperative Group for Neuroblastoma.
De Bernardi B, Conte M, Mancini A, Donfrancesco A, Alvisi P, Tomà P, Casale F, Cordero di Montezemolo L, Cornelli PE, Carli M
J Clin Oncol 1995 Apr;13(4):884-93. doi: 10.1200/JCO.1995.13.4.884. PMID: 7707115

Prognosis

Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group.
Ambros IM, Tonini GP, Pötschger U, Gross N, Mosseri V, Beiske K, Berbegall AP, Bénard J, Bown N, Caron H, Combaret V, Couturier J, Defferrari R, Delattre O, Jeison M, Kogner P, Lunec J, Marques B, Martinsson T, Mazzocco K, Noguera R, Schleiermacher G, Valent A, Van Roy N, Villamon E, Janousek D, Pribill I, Glogova E, Attiyeh EF, Hogarty MD, Monclair TF, Holmes K, Valteau-Couanet D, Castel V, Tweddle DA, Park JR, Cohn S, Ladenstein R, Beck-Popovic M, De Bernardi B, Michon J, Pearson ADJ, Ambros PF
J Clin Oncol 2020 Nov 1;38(31):3685-3697. Epub 2020 Sep 9 doi: 10.1200/JCO.18.02132. PMID: 32903140Free PMC Article
Identification of novel prognostic markers in relapsing localized resectable neuroblastoma.
Parodi F, Passoni L, Massimo L, Luksch R, Gambini C, Rossi E, Zuffardi O, Pistoia V, Pezzolo A
OMICS 2011 Mar;15(3):113-21. Epub 2011 Feb 14 doi: 10.1089/omi.2010.0085. PMID: 21319993
Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.
Pezzolo A, Rossi E, Gimelli S, Parodi F, Negri F, Conte M, Pistorio A, Sementa A, Pistoia V, Zuffardi O, Gambini C
Neuro Oncol 2009 Apr;11(2):192-200. Epub 2008 Oct 15 doi: 10.1215/15228517-2008-086. PMID: 18923191Free PMC Article
Localized resectable neuroblastoma: results of the second study of the Italian Cooperative Group for Neuroblastoma.
De Bernardi B, Conte M, Mancini A, Donfrancesco A, Alvisi P, Tomà P, Casale F, Cordero di Montezemolo L, Cornelli PE, Carli M
J Clin Oncol 1995 Apr;13(4):884-93. doi: 10.1200/JCO.1995.13.4.884. PMID: 7707115
Localized neuroblastoma treated by surgery: a Pediatric Oncology Group Study.
Nitschke R, Smith EI, Shochat S, Altshuler G, Travers H, Shuster JJ, Hayes FA, Patterson R, McWilliams N
J Clin Oncol 1988 Aug;6(8):1271-9. doi: 10.1200/JCO.1988.6.8.1271. PMID: 3411339

Clinical prediction guides

Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group.
Ambros IM, Tonini GP, Pötschger U, Gross N, Mosseri V, Beiske K, Berbegall AP, Bénard J, Bown N, Caron H, Combaret V, Couturier J, Defferrari R, Delattre O, Jeison M, Kogner P, Lunec J, Marques B, Martinsson T, Mazzocco K, Noguera R, Schleiermacher G, Valent A, Van Roy N, Villamon E, Janousek D, Pribill I, Glogova E, Attiyeh EF, Hogarty MD, Monclair TF, Holmes K, Valteau-Couanet D, Castel V, Tweddle DA, Park JR, Cohn S, Ladenstein R, Beck-Popovic M, De Bernardi B, Michon J, Pearson ADJ, Ambros PF
J Clin Oncol 2020 Nov 1;38(31):3685-3697. Epub 2020 Sep 9 doi: 10.1200/JCO.18.02132. PMID: 32903140Free PMC Article
Identification of novel prognostic markers in relapsing localized resectable neuroblastoma.
Parodi F, Passoni L, Massimo L, Luksch R, Gambini C, Rossi E, Zuffardi O, Pistoia V, Pezzolo A
OMICS 2011 Mar;15(3):113-21. Epub 2011 Feb 14 doi: 10.1089/omi.2010.0085. PMID: 21319993
Presence of 1q gain and absence of 7p gain are new predictors of local or metastatic relapse in localized resectable neuroblastoma.
Pezzolo A, Rossi E, Gimelli S, Parodi F, Negri F, Conte M, Pistorio A, Sementa A, Pistoia V, Zuffardi O, Gambini C
Neuro Oncol 2009 Apr;11(2):192-200. Epub 2008 Oct 15 doi: 10.1215/15228517-2008-086. PMID: 18923191Free PMC Article
Localized neuroblastoma treated by surgery: a Pediatric Oncology Group Study.
Nitschke R, Smith EI, Shochat S, Altshuler G, Travers H, Shuster JJ, Hayes FA, Patterson R, McWilliams N
J Clin Oncol 1988 Aug;6(8):1271-9. doi: 10.1200/JCO.1988.6.8.1271. PMID: 3411339

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