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Dextrocardia Situs Solitus

MedGen UID:
768595
•Concept ID:
C3639955
•
Congenital Abnormality
Synonym: Dextrocardia Normal Situs

Definition

A congenital heart defect in which the heart is located in the right side and the other organs are in their normal position. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDextrocardia Situs Solitus

Professional guidelines

PubMed

Laterality Defects in Primary Ciliary Dyskinesia: Relationship to Ultrastructural Defect or Genotype.
Barber AT, Shapiro AJ, Davis SD, Ferkol TW, Atkinson JJ, Sagel SD, Dell SD, Olivier KN, Milla CE, Rosenfeld M, Li L, Lin FC, Sullivan KM, Capps NA, Zariwala MA, Knowles MR, Leigh MW
Ann Am Thorac Soc 2023 Mar;20(3):397-405. doi: 10.1513/AnnalsATS.202206-487OC. PMID: 36342963Free PMC Article
Double outlet left ventricle. Morphology, cineangiocardiographic diagnosis and surgical treatment.
Brandt PW, Calder AL, Barratt-Boyes BG, Neutze JM
Am J Cardiol 1976 Dec;38(7):897-909. doi: 10.1016/0002-9149(76)90803-1. PMID: 998525

Recent clinical studies

Diagnosis

Dextrocardia, situs solitus, inlet ventricular septal defect (VSD), and iatrogenic tricuspid regurgitation (TR)-A surgical perspective.
Mahajan S, Khanna S, Kumar B, Halder V
J Card Surg 2020 Jun;35(6):1383-1386. Epub 2020 Apr 29 doi: 10.1111/jocs.14587. PMID: 32349171
Left-sided approach for mitral valve replacement in a case of dextrocardia with situs solitus.
Kikon M, Kazmi A, Gupta A, Grover V
Interact Cardiovasc Thorac Surg 2013 Nov;17(5):900-2. Epub 2013 Aug 2 doi: 10.1093/icvts/ivt314. PMID: 23912624Free PMC Article

Prognosis

BMP2 is a potential causative gene for isolated dextrocardia situs solitus.
Yogi A, Iemura R, Nakatani H, Takasawa K, Gau M, Yamauchi T, Yoshida M, Moriyama K, Ishii T, Hosokawa S, Yamada M, Suzuki H, Kosaki K, Kashimada K, Morio T
Eur J Med Genet 2023 Sep;66(9):104820. Epub 2023 Aug 11 doi: 10.1016/j.ejmg.2023.104820. PMID: 37572998

Clinical prediction guides

BMP2 is a potential causative gene for isolated dextrocardia situs solitus.
Yogi A, Iemura R, Nakatani H, Takasawa K, Gau M, Yamauchi T, Yoshida M, Moriyama K, Ishii T, Hosokawa S, Yamada M, Suzuki H, Kosaki K, Kashimada K, Morio T
Eur J Med Genet 2023 Sep;66(9):104820. Epub 2023 Aug 11 doi: 10.1016/j.ejmg.2023.104820. PMID: 37572998

Supplemental Content

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    Practice guidelines

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