U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Norepinephrine-Secreting

MedGen UID:
770306
•Concept ID:
C3641666
•
Finding
Synonym: Norepinephrine Secreting

Definition

A finding indicating that an excess amount of norepinephrine is secreted by a tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNorepinephrine-Secreting

Professional guidelines

PubMed

Comprehensive review of evaluation and management of cardiac paragangliomas.
Tella SH, Jha A, Taïeb D, Horvath KA, Pacak K
Heart 2020 Aug;106(16):1202-1210. Epub 2020 May 22 doi: 10.1136/heartjnl-2020-316540. PMID: 32444502Free PMC Article

Recent clinical studies

Etiology

Comprehensive review of evaluation and management of cardiac paragangliomas.
Tella SH, Jha A, Taïeb D, Horvath KA, Pacak K
Heart 2020 Aug;106(16):1202-1210. Epub 2020 May 22 doi: 10.1136/heartjnl-2020-316540. PMID: 32444502Free PMC Article
HEREDITARY ENDOCRINE TUMOURS: CURRENT STATE-OF-THE-ART AND RESEARCH OPPORTUNITIES: Metastatic pheochromocytomas and paragangliomas: proceedings of the MEN2019 workshop.
Dahia PLM, Clifton-Bligh R, Gimenez-Roqueplo AP, Robledo M, Jimenez C
Endocr Relat Cancer 2020 Aug;27(8):T41-T52. doi: 10.1530/ERC-19-0435. PMID: 32069214Free PMC Article
Genetics and biology of pheochromocytoma.
Mannelli M, Simi L, Gaglianò MS, Opocher G, Ercolino T, Becherini L, Parenti G
Exp Clin Endocrinol Diabetes 2007 Mar;115(3):160-5. doi: 10.1055/s-2007-970407. PMID: 17427103
The role of epinephrine, norepinephrine, and dopamine in blood pressure disturbances in patients with pheochromocytoma.
Ito Y, Fujimoto Y, Obara T
World J Surg 1992 Jul-Aug;16(4):759-63; discussion 763-4. doi: 10.1007/BF02067379. PMID: 1413846
Anxiety in patients with pheochromocytomas.
Starkman MN, Zelnik TC, Nesse RM, Cameron OG
Arch Intern Med 1985 Feb;145(2):248-52. PMID: 3977483

Diagnosis

Catecholamine-induced cardiomyopathy improvement after para-aortic paraganglioma resection: a case report.
Ranjbar M, Amin A, Totonchi Z, Ghaemmaghami Z, Jalilian Z, Hesami M, Givtaj N, Jadbabaei AN, Divanbeigi I, Mazloomfard MM
ESC Heart Fail 2022 Feb;9(1):213-218. Epub 2021 Dec 29 doi: 10.1002/ehf2.13783. PMID: 34967117Free PMC Article
Comprehensive review of evaluation and management of cardiac paragangliomas.
Tella SH, Jha A, Taïeb D, Horvath KA, Pacak K
Heart 2020 Aug;106(16):1202-1210. Epub 2020 May 22 doi: 10.1136/heartjnl-2020-316540. PMID: 32444502Free PMC Article
HEREDITARY ENDOCRINE TUMOURS: CURRENT STATE-OF-THE-ART AND RESEARCH OPPORTUNITIES: Metastatic pheochromocytomas and paragangliomas: proceedings of the MEN2019 workshop.
Dahia PLM, Clifton-Bligh R, Gimenez-Roqueplo AP, Robledo M, Jimenez C
Endocr Relat Cancer 2020 Aug;27(8):T41-T52. doi: 10.1530/ERC-19-0435. PMID: 32069214Free PMC Article
Anxiety in patients with pheochromocytomas.
Starkman MN, Zelnik TC, Nesse RM, Cameron OG
Arch Intern Med 1985 Feb;145(2):248-52. PMID: 3977483
A NOREPINEPHRINE-SECRETING GLOMIC TISSUE TUMOR (CHEMODECTOMA).
DUKE WM, PHILLIPS MW, DONALD JM Jr, BOSHELL BR
JAMA 1965 Jul 5;193:20-2. doi: 10.1001/jama.1965.03090010026006. PMID: 14297705

Therapy

Comprehensive review of evaluation and management of cardiac paragangliomas.
Tella SH, Jha A, Taïeb D, Horvath KA, Pacak K
Heart 2020 Aug;106(16):1202-1210. Epub 2020 May 22 doi: 10.1136/heartjnl-2020-316540. PMID: 32444502Free PMC Article
Laparoscopic approach to pheochromocytoma: is a lower intraabdominal pressure helpful?
Sood J, Jayaraman L, Kumra VP, Chowbey PK
Anesth Analg 2006 Feb;102(2):637-41. doi: 10.1213/01.ane.0000184816.00346.65. PMID: 16428576
Efficacy and safety of doxazosin for perioperative management of patients with pheochromocytoma.
Prys-Roberts C, Farndon JR
World J Surg 2002 Aug;26(8):1037-42. Epub 2002 Jun 19 doi: 10.1007/s00268-002-6667-z. PMID: 12192533
Long-term effects of radiation therapy for a catecholamine-producing glomus jugulare tumor. Case report.
Pluta RM, Ram Z, Patronas NJ, Keiser H
J Neurosurg 1994 Jun;80(6):1091-4. doi: 10.3171/jns.1994.80.6.1091. PMID: 8189265
Pheochromocytoma resistant to alpha-adrenergic blockade.
Hauptman JB, Modlinger RS, Ertel NH
Arch Intern Med 1983 Dec;143(12):2321-3. PMID: 6139989

Prognosis

Comprehensive review of evaluation and management of cardiac paragangliomas.
Tella SH, Jha A, Taïeb D, Horvath KA, Pacak K
Heart 2020 Aug;106(16):1202-1210. Epub 2020 May 22 doi: 10.1136/heartjnl-2020-316540. PMID: 32444502Free PMC Article
HEREDITARY ENDOCRINE TUMOURS: CURRENT STATE-OF-THE-ART AND RESEARCH OPPORTUNITIES: Metastatic pheochromocytomas and paragangliomas: proceedings of the MEN2019 workshop.
Dahia PLM, Clifton-Bligh R, Gimenez-Roqueplo AP, Robledo M, Jimenez C
Endocr Relat Cancer 2020 Aug;27(8):T41-T52. doi: 10.1530/ERC-19-0435. PMID: 32069214Free PMC Article
Dopamine-secreting pheochromocytomas: in search of a syndrome.
Dubois LA, Gray DK
World J Surg 2005 Jul;29(7):909-13. doi: 10.1007/s00268-005-7860-7. PMID: 15951922
Long-term effects of radiation therapy for a catecholamine-producing glomus jugulare tumor. Case report.
Pluta RM, Ram Z, Patronas NJ, Keiser H
J Neurosurg 1994 Jun;80(6):1091-4. doi: 10.3171/jns.1994.80.6.1091. PMID: 8189265
Dopamine- and norepinephrine-secreting intrapericardial pheochromocytoma in a normotensive patient.
Awoke S, Perlstein RS
South Med J 1985 Aug;78(8):994-8. doi: 10.1097/00007611-198508000-00027. PMID: 4023796

Clinical prediction guides

Functional hyperactivity in long QT syndrome type 1 pluripotent stem cell-derived sympathetic neurons.
Winbo A, Ramanan S, Eugster E, Rydberg A, Jovinge S, Skinner JR, Montgomery JM
Am J Physiol Heart Circ Physiol 2021 Jul 1;321(1):H217-H227. Epub 2021 Jun 18 doi: 10.1152/ajpheart.01002.2020. PMID: 34142889
Comprehensive review of evaluation and management of cardiac paragangliomas.
Tella SH, Jha A, Taïeb D, Horvath KA, Pacak K
Heart 2020 Aug;106(16):1202-1210. Epub 2020 May 22 doi: 10.1136/heartjnl-2020-316540. PMID: 32444502Free PMC Article
HEREDITARY ENDOCRINE TUMOURS: CURRENT STATE-OF-THE-ART AND RESEARCH OPPORTUNITIES: Metastatic pheochromocytomas and paragangliomas: proceedings of the MEN2019 workshop.
Dahia PLM, Clifton-Bligh R, Gimenez-Roqueplo AP, Robledo M, Jimenez C
Endocr Relat Cancer 2020 Aug;27(8):T41-T52. doi: 10.1530/ERC-19-0435. PMID: 32069214Free PMC Article
Genetics and biology of pheochromocytoma.
Mannelli M, Simi L, Gaglianò MS, Opocher G, Ercolino T, Becherini L, Parenti G
Exp Clin Endocrinol Diabetes 2007 Mar;115(3):160-5. doi: 10.1055/s-2007-970407. PMID: 17427103
Long-term effects of radiation therapy for a catecholamine-producing glomus jugulare tumor. Case report.
Pluta RM, Ram Z, Patronas NJ, Keiser H
J Neurosurg 1994 Jun;80(6):1091-4. doi: 10.3171/jns.1994.80.6.1091. PMID: 8189265

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...