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Angiotensin Converting Enzyme Inhibitor Fetopathy

MedGen UID:
810713
Concept ID:
C0919881
Disease or Syndrome
Synonym: ACE Inhibitor Fetopathy

Definition

Fetal embryopathy associated with maternal angiotensis converting enzyme (ACE) inhibitor use during pregnancy that may include fetal acute renal failure, growth restriction, oligohydramnios, calvaria abnormalities, preterm birth, and pulmonary hypoplasia with respiratory distress. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAngiotensin Converting Enzyme Inhibitor Fetopathy

Recent clinical studies

Etiology

Pryde PG, Sedman AB, Nugent CE, Barr M Jr
J Am Soc Nephrol 1993 Mar;3(9):1575-82. doi: 10.1681/ASN.V391575. PMID: 8507813

Diagnosis

Mercado-Deane MG, Beeson JE, John SD
Radiographics 2002 Nov-Dec;22(6):1429-38. doi: 10.1148/rg.226025047. PMID: 12432113

Therapy

Laube GF, Kemper MJ, Schubiger G, Neuhaus TJ
Arch Dis Child Fetal Neonatal Ed 2007 Sep;92(5):F402-3. Epub 2007 Feb 6 doi: 10.1136/adc.2006.101717. PMID: 17284475Free PMC Article
Hegde AU, Parekji S, Ali US, Mehta KP
Indian Pediatr 1999 Jan;36(1):79-82. PMID: 10709127
Sedman AB, Kershaw DB, Bunchman TE
Pediatr Nephrol 1995 Jun;9(3):382-5. doi: 10.1007/BF02254221. PMID: 7632538
Pryde PG, Sedman AB, Nugent CE, Barr M Jr
J Am Soc Nephrol 1993 Mar;3(9):1575-82. doi: 10.1681/ASN.V391575. PMID: 8507813
Barr M Jr, Cohen MM Jr
Teratology 1991 Nov;44(5):485-95. doi: 10.1002/tera.1420440503. PMID: 1771591

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