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Diabetic kidney disease

MedGen UID:
8352
Concept ID:
C0011881
Disease or Syndrome
Synonym: Diabetic nephropathy
SNOMED CT: Diabetic nephropathy (127013003); Renal disorder associated with diabetes mellitus (127013003); Diabetic renal disease (127013003); Kidney disorder due to diabetes mellitus (127013003); Disorder of kidney due to diabetes mellitus (127013003)
 
Monarch Initiative: MONDO:0005016

Definition

Progressive kidney disorder caused by vascular damage to the glomerular capillaries, in patients with diabetes mellitus. It is usually manifested with nephritic syndrome and glomerulosclerosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiabetic kidney disease

Professional guidelines

PubMed

Blonde L, Umpierrez GE, Reddy SS, McGill JB, Berga SL, Bush M, Chandrasekaran S, DeFronzo RA, Einhorn D, Galindo RJ, Gardner TW, Garg R, Garvey WT, Hirsch IB, Hurley DL, Izuora K, Kosiborod M, Olson D, Patel SB, Pop-Busui R, Sadhu AR, Samson SL, Stec C, Tamborlane WV Jr, Tuttle KR, Twining C, Vella A, Vellanki P, Weber SL
Endocr Pract 2022 Oct;28(10):923-1049. Epub 2022 Aug 11 doi: 10.1016/j.eprac.2022.08.002. PMID: 35963508Free PMC Article
Yamazaki T, Mimura I, Tanaka T, Nangaku M
Diabetes Metab J 2021 Jan;45(1):11-26. Epub 2021 Jan 22 doi: 10.4093/dmj.2020.0217. PMID: 33508907Free PMC Article
Lin YC, Chang YH, Yang SY, Wu KD, Chu TS
J Formos Med Assoc 2018 Aug;117(8):662-675. Epub 2018 Mar 2 doi: 10.1016/j.jfma.2018.02.007. PMID: 29486908

Recent clinical studies

Etiology

Tuttle KR, Agarwal R, Alpers CE, Bakris GL, Brosius FC, Kolkhof P, Uribarri J
Kidney Int 2022 Aug;102(2):248-260. Epub 2022 Jun 3 doi: 10.1016/j.kint.2022.05.012. PMID: 35661785
Jung CY, Yoo TH
Diabetes Metab J 2022 Mar;46(2):181-197. Epub 2022 Mar 24 doi: 10.4093/dmj.2021.0329. PMID: 35385633Free PMC Article
Bonner R, Albajrami O, Hudspeth J, Upadhyay A
Prim Care 2020 Dec;47(4):645-659. Epub 2020 Sep 23 doi: 10.1016/j.pop.2020.08.004. PMID: 33121634
Alicic RZ, Rooney MT, Tuttle KR
Clin J Am Soc Nephrol 2017 Dec 7;12(12):2032-2045. Epub 2017 May 18 doi: 10.2215/CJN.11491116. PMID: 28522654Free PMC Article
Thomas MC, Brownlee M, Susztak K, Sharma K, Jandeleit-Dahm KA, Zoungas S, Rossing P, Groop PH, Cooper ME
Nat Rev Dis Primers 2015 Jul 30;1:15018. doi: 10.1038/nrdp.2015.18. PMID: 27188921Free PMC Article

Diagnosis

Gupta S, Dominguez M, Golestaneh L
Med Clin North Am 2023 Jul;107(4):689-705. Epub 2023 Apr 7 doi: 10.1016/j.mcna.2023.03.004. PMID: 37258007
Crasto W, Patel V, Davies MJ, Khunti K
Endocrinol Metab Clin North Am 2021 Sep;50(3):431-455. doi: 10.1016/j.ecl.2021.05.005. PMID: 34399955
Bonner R, Albajrami O, Hudspeth J, Upadhyay A
Prim Care 2020 Dec;47(4):645-659. Epub 2020 Sep 23 doi: 10.1016/j.pop.2020.08.004. PMID: 33121634
Lin YC, Chang YH, Yang SY, Wu KD, Chu TS
J Formos Med Assoc 2018 Aug;117(8):662-675. Epub 2018 Mar 2 doi: 10.1016/j.jfma.2018.02.007. PMID: 29486908
Alicic RZ, Rooney MT, Tuttle KR
Clin J Am Soc Nephrol 2017 Dec 7;12(12):2032-2045. Epub 2017 May 18 doi: 10.2215/CJN.11491116. PMID: 28522654Free PMC Article

Therapy

Rayego-Mateos S, Rodrigues-Diez RR, Fernandez-Fernandez B, Mora-Fernández C, Marchant V, Donate-Correa J, Navarro-González JF, Ortiz A, Ruiz-Ortega M
Kidney Int 2023 Feb;103(2):282-296. Epub 2022 Dec 5 doi: 10.1016/j.kint.2022.10.030. PMID: 36470394
Yamazaki T, Mimura I, Tanaka T, Nangaku M
Diabetes Metab J 2021 Jan;45(1):11-26. Epub 2021 Jan 22 doi: 10.4093/dmj.2020.0217. PMID: 33508907Free PMC Article
Bonner R, Albajrami O, Hudspeth J, Upadhyay A
Prim Care 2020 Dec;47(4):645-659. Epub 2020 Sep 23 doi: 10.1016/j.pop.2020.08.004. PMID: 33121634
Pérez-Morales RE, Del Pino MD, Valdivielso JM, Ortiz A, Mora-Fernández C, Navarro-González JF
Nephron 2019;143(1):12-16. Epub 2018 Oct 1 doi: 10.1159/000493278. PMID: 30273931
Alicic RZ, Rooney MT, Tuttle KR
Clin J Am Soc Nephrol 2017 Dec 7;12(12):2032-2045. Epub 2017 May 18 doi: 10.2215/CJN.11491116. PMID: 28522654Free PMC Article

Prognosis

Jung CY, Yoo TH
Diabetes Metab J 2022 Mar;46(2):181-197. Epub 2022 Mar 24 doi: 10.4093/dmj.2021.0329. PMID: 35385633Free PMC Article
Pereira PR, Carrageta DF, Oliveira PF, Rodrigues A, Alves MG, Monteiro MP
Med Res Rev 2022 Jul;42(4):1518-1544. Epub 2022 Mar 10 doi: 10.1002/med.21883. PMID: 35274315
Crasto W, Patel V, Davies MJ, Khunti K
Endocrinol Metab Clin North Am 2021 Sep;50(3):431-455. doi: 10.1016/j.ecl.2021.05.005. PMID: 34399955
Tang SCW, Yiu WH
Nat Rev Nephrol 2020 Apr;16(4):206-222. Epub 2020 Jan 15 doi: 10.1038/s41581-019-0234-4. PMID: 31942046
Reidy K, Kang HM, Hostetter T, Susztak K
J Clin Invest 2014 Jun;124(6):2333-40. Epub 2014 Jun 2 doi: 10.1172/JCI72271. PMID: 24892707Free PMC Article

Clinical prediction guides

Jung CY, Yoo TH
Diabetes Metab J 2022 Mar;46(2):181-197. Epub 2022 Mar 24 doi: 10.4093/dmj.2021.0329. PMID: 35385633Free PMC Article
Crasto W, Patel V, Davies MJ, Khunti K
Endocrinol Metab Clin North Am 2021 Sep;50(3):431-455. doi: 10.1016/j.ecl.2021.05.005. PMID: 34399955
Wan H, Wang Y, Xiang Q, Fang S, Chen Y, Chen C, Zhang W, Zhang H, Xia F, Wang N, Lu Y
Cardiovasc Diabetol 2020 Jul 31;19(1):118. doi: 10.1186/s12933-020-01095-4. PMID: 32736628Free PMC Article
Doshi SM, Friedman AN
Clin J Am Soc Nephrol 2017 Aug 7;12(8):1366-1373. Epub 2017 Mar 9 doi: 10.2215/CJN.11111016. PMID: 28280116Free PMC Article
Reidy K, Kang HM, Hostetter T, Susztak K
J Clin Invest 2014 Jun;124(6):2333-40. Epub 2014 Jun 2 doi: 10.1172/JCI72271. PMID: 24892707Free PMC Article

Recent systematic reviews

Liu Y, An C, Liu P, Yang F, Zhao Q
Ren Fail 2023 Dec;45(1):2217287. doi: 10.1080/0886022X.2023.2217287. PMID: 37246403Free PMC Article
Jiang S, Fang J, Li W
Cochrane Database Syst Rev 2023 Jan 3;1(1):CD014906. doi: 10.1002/14651858.CD014906.pub2. PMID: 36594428Free PMC Article
Singh AK, Singh A, Singh R, Misra A
Diabetes Metab Syndr 2022 Oct;16(10):102638. Epub 2022 Oct 4 doi: 10.1016/j.dsx.2022.102638. PMID: 36223666
Kaze AD, Zhuo M, Kim SC, Patorno E, Paik JM
Cardiovasc Diabetol 2022 Mar 23;21(1):47. doi: 10.1186/s12933-022-01476-x. PMID: 35321742Free PMC Article
Jiang W, Wang J, Shen X, Lu W, Wang Y, Li W, Gao Z, Xu J, Li X, Liu R, Zheng M, Chang B, Li J, Yang J, Chang B
Diabetes Care 2020 Apr;43(4):925-933. doi: 10.2337/dc19-1897. PMID: 32198286

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