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Benign connective and soft tissue neoplasm

MedGen UID:
83866
Concept ID:
C0347481
Neoplastic Process
Synonyms: Benign Connective and Soft Tissue Neoplasm; benign connective and soft tissue neoplasm; Benign Connective and Soft Tissue Tumor; benign connective and soft tissue tumor; benign connective and soft tissue tumour; Benign Mesenchymal Cell Neoplasm; benign mesenchymal cell neoplasm; Benign Neoplasm of the Soft Tissue and Bone; benign neoplasm of the soft tissue and bone; Benign Tumor of the Soft Tissue and Bone; benign tumor of the soft tissue and bone; benign tumour of the soft tissue and bone; connective and soft tissue neoplasm, benign; connective tissue benign neoplasm; neoplasm of soft tissue; neoplasm of soft tissues; soft tissue benign neoplasm; tumor of the soft tissue; tumour of the soft tissue
 
Monarch Initiative: MONDO:0000654

Definition

A neoplasm that arises from connective and soft tissue and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include lipoma, leiomyoma, fibroma, and osteoma. [from NCI]

Professional guidelines

PubMed

Jacobson BC, Bhatt A, Greer KB, Lee LS, Park WG, Sauer BG, Shami VM
Am J Gastroenterol 2023 Jan 1;118(1):46-58. Epub 2022 Sep 6 doi: 10.14309/ajg.0000000000002100. PMID: 36602835
Kanakis GA, Nordkap L, Bang AK, Calogero AE, Bártfai G, Corona G, Forti G, Toppari J, Goulis DG, Jørgensen N
Andrology 2019 Nov;7(6):778-793. Epub 2019 May 16 doi: 10.1111/andr.12636. PMID: 31099174
De La Cruz MS, Buchanan EM
Am Fam Physician 2017 Jan 15;95(2):100-107. PMID: 28084714

Recent clinical studies

Etiology

Kager M, Kager R, Fałek P, Fałek A, Szczypiór G, Niemunis-Sawicka J, Rzepecka-Wejs L, Starosławska E, Burdan F
Folia Med Cracov 2022;62(2):93-107. doi: 10.24425/fmc.2022.141702. PMID: 36256897
Zhang Y, Kleer CG
Arch Pathol Lab Med 2016 Jul;140(7):665-71. doi: 10.5858/arpa.2016-0042-RA. PMID: 27362571
Qasem SA, DeYoung BR
Semin Diagn Pathol 2014 Jan;31(1):10-20. Epub 2014 Jan 23 doi: 10.1053/j.semdp.2014.01.006. PMID: 24680178
Ceyssens S, Stroobants S
Methods Mol Biol 2011;727:191-203. doi: 10.1007/978-1-61779-062-1_11. PMID: 21331935
Salam GA
Am Fam Physician 2002 Mar 1;65(5):901-4. PMID: 11898962

Diagnosis

Yee EJ, Stewart CL, Clay MR, McCarter MM
Surg Clin North Am 2022 Aug;102(4):637-656. doi: 10.1016/j.suc.2022.04.006. PMID: 35952693
Lerwill MF, Lee AHS, Tan PH
Virchows Arch 2022 Jan;480(1):45-63. Epub 2021 Sep 10 doi: 10.1007/s00428-021-03175-6. PMID: 34505197
Temple EW, Prusa RD
Clin Podiatr Med Surg 2021 Apr;38(2):227-233. Epub 2021 Jan 26 doi: 10.1016/j.cpm.2020.12.007. PMID: 33745653
Florenzano P, Hartley IR, Jimenez M, Roszko K, Gafni RI, Collins MT
Calcif Tissue Int 2021 Jan;108(1):128-142. Epub 2020 Jun 5 doi: 10.1007/s00223-020-00691-6. PMID: 32504138
Salam GA
Am Fam Physician 2002 Mar 1;65(5):901-4. PMID: 11898962

Therapy

Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922
Kager M, Kager R, Fałek P, Fałek A, Szczypiór G, Niemunis-Sawicka J, Rzepecka-Wejs L, Starosławska E, Burdan F
Folia Med Cracov 2022;62(2):93-107. doi: 10.24425/fmc.2022.141702. PMID: 36256897
Florenzano P, Hartley IR, Jimenez M, Roszko K, Gafni RI, Collins MT
Calcif Tissue Int 2021 Jan;108(1):128-142. Epub 2020 Jun 5 doi: 10.1007/s00223-020-00691-6. PMID: 32504138
Metwally M, Raybould G, Cheong YC, Horne AW
Cochrane Database Syst Rev 2020 Jan 29;1(1):CD003857. doi: 10.1002/14651858.CD003857.pub4. PMID: 31995657Free PMC Article
Donnez J, Dolmans MM
Hum Reprod Update 2016 Nov;22(6):665-686. Epub 2016 Jul 27 doi: 10.1093/humupd/dmw023. PMID: 27466209Free PMC Article

Prognosis

Spinnato P, Chiesa AM, Ledoux P, Kind M, Bianchi G, Tuzzato G, Righi A, Crombé A
Acad Radiol 2023 Feb;30(2):285-299. Epub 2022 Sep 7 doi: 10.1016/j.acra.2022.08.009. PMID: 36088202
Jendouzi O, Boukhlifi Y, Houadfi OE, Essaoudi MA, Alami M, Ameur A
Pan Afr Med J 2020;37:380. Epub 2020 Dec 29 doi: 10.11604/pamj.2020.37.380.25672. PMID: 33796193Free PMC Article
Johnson CN, Ha AS, Chen E, Davidson D
J Am Acad Orthop Surg 2018 Nov 15;26(22):779-788. doi: 10.5435/JAAOS-D-17-00045. PMID: 30192249
Ferrari A, Orbach D, Sultan I, Casanova M, Bisogno G
Semin Fetal Neonatal Med 2012 Aug;17(4):231-238. Epub 2012 May 25 doi: 10.1016/j.siny.2012.05.003. PMID: 22633289
Shields CJ, Winter DC, Kirwan WO, Redmond HP
Eur J Surg Oncol 2001 Dec;27(8):701-6. doi: 10.1053/ejso.2001.1169. PMID: 11735163

Clinical prediction guides

Haseli S, Mansoori B, Christensen D, Abadi A, Pooyan A, Shomal Zadeh F, Mau B, Khalili N, Murphey M, Chalian M
Radiographics 2023 Aug;43(8):e230005. doi: 10.1148/rg.230005. PMID: 37440448
Yu J, Kansal K
Surg Clin North Am 2022 Dec;102(6):1017-1030. doi: 10.1016/j.suc.2022.07.002. PMID: 36335922
Felty CC, Linos K
Am J Dermatopathol 2019 Dec;41(12):879-883. doi: 10.1097/DAD.0000000000001272. PMID: 30289773
Baker GM, Schnitt SJ
Semin Diagn Pathol 2017 Sep;34(5):410-419. Epub 2017 May 30 doi: 10.1053/j.semdp.2017.05.013. PMID: 28676174
Antonescu C
Mod Pathol 2014 Jan;27 Suppl 1:S30-8. doi: 10.1038/modpathol.2013.176. PMID: 24384851

Recent systematic reviews

Yu CY, Huang TW, Tam KW
Int J Surg 2022 Nov;107:106969. Epub 2022 Oct 31 doi: 10.1016/j.ijsu.2022.106969. PMID: 36328344
Sparić R, Andjić M, Babović I, Nejković L, Mitrović M, Štulić J, Pupovac M, Tinelli A
Int J Mol Sci 2022 Aug 27;23(17) doi: 10.3390/ijms23179728. PMID: 36077127Free PMC Article
Lissidini G, Mulè A, Santoro A, Papa G, Nicosia L, Cassano E, Ashoor AA, Veronesi P, Pantanowitz L, Hornick JL, Rossi ED
Pathologica 2022 Apr;114(2):111-120. Epub 2022 Apr 13 doi: 10.32074/1591-951X-754. PMID: 35414723Free PMC Article
Vázquez Fernández R, Maneiro Fernández JR, Cervantes Pérez EC, Mera Varela A
Ir J Med Sci 2021 Aug;190(3):1005-1014. Epub 2020 Oct 1 doi: 10.1007/s11845-020-02378-1. PMID: 33006046
Metwally M, Raybould G, Cheong YC, Horne AW
Cochrane Database Syst Rev 2020 Jan 29;1(1):CD003857. doi: 10.1002/14651858.CD003857.pub4. PMID: 31995657Free PMC Article

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