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Abnormality of peripheral nervous system electrophysiology

MedGen UID:
852897
•Concept ID:
C0853150
•
Finding
Synonym: Abnormal nerve conduction study
 
HPO: HP:0030177

Definition

An abnormality of the function of the electrical signals with which peripheral nerve cells communicate with each other or with muscles. [from HPO]

Professional guidelines

PubMed

WFS1-Associated Optic Neuropathy: Genotype-Phenotype Correlations and Disease Progression.
Majander A, Jurkute N, Burté F, Brock K, João C, Huang H, Neveu MM, Chan CM, Duncan HJ, Kelly S, Burkitt-Wright E, Khoyratty F, Lai YT, Subash M, Chinnery PF, Bitner-Glindzicz M, Arno G, Webster AR, Moore AT, Michaelides M, Stockman A, Robson AG, Yu-Wai-Man P
Am J Ophthalmol 2022 Sep;241:9-27. Epub 2022 Apr 22 doi: 10.1016/j.ajo.2022.04.003. PMID: 35469785
Chronic inflammatory demyelinating polyradiculoneuropathy: can a diagnosis be made in patients not fulfilling electrodiagnostic criteria?
Liberatore G, Manganelli F, Doneddu PE, Cocito D, Fazio R, Briani C, Filosto M, Benedetti L, Mazzeo A, Antonini G, Cosentino G, Jann S, Cortese A, Marfia GA, Clerici AM, Siciliano G, Carpo M, Luigetti M, Lauria G, Rosso T, Cavaletti G, Santoro L, Peci E, Tronci S, Ruiz M, Cotti Piccinelli S, Schenone A, Leonardi L, Toscano A, Mataluni G, Spina E, Gentile L, Nobile-Orazio E; Italian CIDP Database Study Group
Eur J Neurol 2021 Feb;28(2):620-629. Epub 2020 Oct 15 doi: 10.1111/ene.14545. PMID: 32959475
Role of the neurologist in hazard identification and risk assessment.
Feldman RG, White RF
Environ Health Perspect 1996 Apr;104 Suppl 2(Suppl 2):227-37. doi: 10.1289/ehp.96104s2227. PMID: 9182031Free PMC Article

Recent clinical studies

Etiology

Atrial fibrillation: Neurogenic or myogenic?
Scridon A, Şerban RC, Chevalier P
Arch Cardiovasc Dis 2018 Jan;111(1):59-69. Epub 2017 Dec 8 doi: 10.1016/j.acvd.2017.11.001. PMID: 29229215
Electrophysiology in Fisher syndrome.
Kuwabara S, Sekiguchi Y, Misawa S
Clin Neurophysiol 2017 Jan;128(1):215-219. Epub 2016 Nov 20 doi: 10.1016/j.clinph.2016.11.009. PMID: 27923188
The electrophysiology of spinocerebellar ataxias.
Liang L, Chen T, Wu Y
Neurophysiol Clin 2016 Feb;46(1):27-34. Epub 2016 Mar 2 doi: 10.1016/j.neucli.2015.12.006. PMID: 26947625
Diagnosis of Charcot-Marie-Tooth disease.
Banchs I, Casasnovas C, Albertí A, De Jorge L, Povedano M, Montero J, Martínez-Matos JA, Volpini V
J Biomed Biotechnol 2009;2009:985415. Epub 2009 Oct 8 doi: 10.1155/2009/985415. PMID: 19826499Free PMC Article
Porphyric neuropathy.
Albers JW, Fink JK
Muscle Nerve 2004 Oct;30(4):410-22. doi: 10.1002/mus.20137. PMID: 15372536

Diagnosis

Pathophysiology of Takotsubo Syndrome: JACC State-of-the-Art Review.
Lyon AR, Citro R, Schneider B, Morel O, Ghadri JR, Templin C, Omerovic E
J Am Coll Cardiol 2021 Feb 23;77(7):902-921. doi: 10.1016/j.jacc.2020.10.060. PMID: 33602474
Electrophysiology in Fisher syndrome.
Kuwabara S, Sekiguchi Y, Misawa S
Clin Neurophysiol 2017 Jan;128(1):215-219. Epub 2016 Nov 20 doi: 10.1016/j.clinph.2016.11.009. PMID: 27923188
Porphyric neuropathy.
Albers JW, Fink JK
Muscle Nerve 2004 Oct;30(4):410-22. doi: 10.1002/mus.20137. PMID: 15372536
Electrophysiology of radiculopathies.
Fisher MA
Clin Neurophysiol 2002 Mar;113(3):317-35. doi: 10.1016/s1388-2457(02)00018-4. PMID: 11897532
Thoracic outlet syndrome.
Pang D, Wessel HB
Neurosurgery 1988 Jan;22(1 Pt 1):105-21. doi: 10.1227/00006123-198801010-00018. PMID: 3278249

Therapy

Vision at the limits: Absolute threshold, visual function, and outcomes in clinical trials.
Simunovic MP, Grigg JR, Mahroo OA
Surv Ophthalmol 2022 Jul-Aug;67(4):1270-1286. Epub 2022 Jan 31 doi: 10.1016/j.survophthal.2022.01.008. PMID: 35093403
Impact of carpal tunnel syndrome on ulnar nerve at wrist: Systematic review.
Ginanneschi F, Mondelli M, Cioncoloni D, Rossi A
J Electromyogr Kinesiol 2018 Jun;40:32-38. Epub 2018 Mar 20 doi: 10.1016/j.jelekin.2018.03.004. PMID: 29587171
Axonal Guillain-Barré syndrome: concepts and controversies.
Kuwabara S, Yuki N
Lancet Neurol 2013 Dec;12(12):1180-8. doi: 10.1016/S1474-4422(13)70215-1. PMID: 24229616
Post-surgical inflammatory neuropathy.
Staff NP, Engelstad J, Klein CJ, Amrami KK, Spinner RJ, Dyck PJ, Warner MA, Warner ME, Dyck PJ
Brain 2010 Oct;133(10):2866-80. Epub 2010 Sep 15 doi: 10.1093/brain/awq252. PMID: 20846945
Cardiovascular complications of cirrhosis.
Møller S, Henriksen JH
Gut 2008 Feb;57(2):268-78. doi: 10.1136/gut.2006.112177. PMID: 18192456

Prognosis

Electrophysiological measurements of diabetic peripheral neuropathy: A systematic review.
Shabeeb D, Najafi M, Hasanzadeh G, Hadian MR, Musa AE, Shirazi A
Diabetes Metab Syndr 2018 Jul;12(4):591-600. Epub 2018 Mar 28 doi: 10.1016/j.dsx.2018.03.026. PMID: 29610062
Atrial fibrillation: Neurogenic or myogenic?
Scridon A, Şerban RC, Chevalier P
Arch Cardiovasc Dis 2018 Jan;111(1):59-69. Epub 2017 Dec 8 doi: 10.1016/j.acvd.2017.11.001. PMID: 29229215
Cardiac electrophysiology of patients with spinal cord injury.
Manogue M, Hirsh DS, Lloyd M
Heart Rhythm 2017 Jun;14(6):920-927. Epub 2017 Feb 12 doi: 10.1016/j.hrthm.2017.02.015. PMID: 28215570
Electrophysiology in Fisher syndrome.
Kuwabara S, Sekiguchi Y, Misawa S
Clin Neurophysiol 2017 Jan;128(1):215-219. Epub 2016 Nov 20 doi: 10.1016/j.clinph.2016.11.009. PMID: 27923188
Porphyric neuropathy.
Albers JW, Fink JK
Muscle Nerve 2004 Oct;30(4):410-22. doi: 10.1002/mus.20137. PMID: 15372536

Clinical prediction guides

Peripheral nerve involvement in hereditary spastic paraplegia characterized by quantitative magnetic resonance neurography.
Jacobi H, Weiler M, Sam G, Heiland S, Hayes JM, Bendszus M, Schüle R, Hayes JC
Eur J Neurol 2023 Aug;30(8):2442-2452. Epub 2023 May 26 doi: 10.1111/ene.15841. PMID: 37154411
Electrophysiological measurements of diabetic peripheral neuropathy: A systematic review.
Shabeeb D, Najafi M, Hasanzadeh G, Hadian MR, Musa AE, Shirazi A
Diabetes Metab Syndr 2018 Jul;12(4):591-600. Epub 2018 Mar 28 doi: 10.1016/j.dsx.2018.03.026. PMID: 29610062
Atrial fibrillation: Neurogenic or myogenic?
Scridon A, Şerban RC, Chevalier P
Arch Cardiovasc Dis 2018 Jan;111(1):59-69. Epub 2017 Dec 8 doi: 10.1016/j.acvd.2017.11.001. PMID: 29229215
Cardiac electrophysiology of patients with spinal cord injury.
Manogue M, Hirsh DS, Lloyd M
Heart Rhythm 2017 Jun;14(6):920-927. Epub 2017 Feb 12 doi: 10.1016/j.hrthm.2017.02.015. PMID: 28215570
Post-surgical inflammatory neuropathy.
Staff NP, Engelstad J, Klein CJ, Amrami KK, Spinner RJ, Dyck PJ, Warner MA, Warner ME, Dyck PJ
Brain 2010 Oct;133(10):2866-80. Epub 2010 Sep 15 doi: 10.1093/brain/awq252. PMID: 20846945

Recent systematic reviews

Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings.
Guerrero JI, Barragán LA, Martínez JD, Montoya JP, Peña A, Sobrino FE, Tovar-Spinoza Z, Ghotme KA
BMC Infect Dis 2021 Jun 2;21(1):515. doi: 10.1186/s12879-021-06185-6. PMID: 34078305Free PMC Article
Electrophysiological measurements of diabetic peripheral neuropathy: A systematic review.
Shabeeb D, Najafi M, Hasanzadeh G, Hadian MR, Musa AE, Shirazi A
Diabetes Metab Syndr 2018 Jul;12(4):591-600. Epub 2018 Mar 28 doi: 10.1016/j.dsx.2018.03.026. PMID: 29610062
Impact of carpal tunnel syndrome on ulnar nerve at wrist: Systematic review.
Ginanneschi F, Mondelli M, Cioncoloni D, Rossi A
J Electromyogr Kinesiol 2018 Jun;40:32-38. Epub 2018 Mar 20 doi: 10.1016/j.jelekin.2018.03.004. PMID: 29587171
Intermediate Charcot-Marie-Tooth disease: an electrophysiological reappraisal and systematic review.
Berciano J, García A, Gallardo E, Peeters K, Pelayo-Negro AL, Álvarez-Paradelo S, Gazulla J, Martínez-Tames M, Infante J, Jordanova A
J Neurol 2017 Aug;264(8):1655-1677. Epub 2017 Mar 31 doi: 10.1007/s00415-017-8474-3. PMID: 28364294

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