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Adult B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1

MedGen UID:
859700
•Concept ID:
C3900106
•
Neoplastic Process
Synonyms: Adult B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR::ABL1; Adult B Acute Lymphoblastic Leukemia with t(9;22)(q34;q11.2); BCR-ABL1

Definition

A B acute lymphoblastic leukemia that occurs during adulthood. It is characterized by the presence of lymphoblasts that carry a translocation between the BCR gene on chromosome 22 and the ABL1 gene on chromosome 9. It results in the production of the p190 kd or p210 kd fusion protein. It has an unfavorable clinical outcome. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1

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