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Abnormality of the seventh cranial nerve

MedGen UID:
866868
•Concept ID:
C4021223
•
Anatomical Abnormality
Synonym: Abnormality of the facial nerve
 
HPO: HP:0010827

Definition

Abnormality of the seventh cranial nerve sometimes also referred to as the facial nerve. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of the seventh cranial nerve

Professional guidelines

PubMed

Clinical features, treatment and outcome in neurosarcoidosis: systematic review and meta-analysis.
Fritz D, van de Beek D, Brouwer MC
BMC Neurol 2016 Nov 15;16(1):220. doi: 10.1186/s12883-016-0741-x. PMID: 27846819Free PMC Article
Guillain-Barré syndrome: clinical profile and management.
Sudulagunta SR, Sodalagunta MB, Sepehrar M, Khorram H, Bangalore Raja SK, Kothandapani S, Noroozpour Z, Aheta Sham M, Prasad N, Sunny SP, Mohammed MD, Gangadharappa R, Nidsale Sudarshan R
Ger Med Sci 2015;13:Doc16. Epub 2015 Sep 21 doi: 10.3205/000220. PMID: 26421004Free PMC Article
Bell's palsy: diagnosis and management.
Tiemstra JD, Khatkhate N
Am Fam Physician 2007 Oct 1;76(7):997-1002. PMID: 17956069

Recent clinical studies

Etiology

Clinical Presentation of a Complex Neurodevelopmental Disorder Caused by Mutations in ADNP.
Van Dijck A, Vulto-van Silfhout AT, Cappuyns E, van der Werf IM, Mancini GM, Tzschach A, Bernier R, Gozes I, Eichler EE, Romano C, Lindstrand A, Nordgren A; ADNP Consortium, Kvarnung M, Kleefstra T, de Vries BBA, Küry S, Rosenfeld JA, Meuwissen ME, Vandeweyer G, Kooy RF
Biol Psychiatry 2019 Feb 15;85(4):287-297. Epub 2018 Mar 15 doi: 10.1016/j.biopsych.2018.02.1173. PMID: 29724491Free PMC Article
Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder.
Koemans TS, Kleefstra T, Chubak MC, Stone MH, Reijnders MRF, de Munnik S, Willemsen MH, Fenckova M, Stumpel CTRM, Bok LA, Sifuentes Saenz M, Byerly KA, Baughn LB, Stegmann APA, Pfundt R, Zhou H, van Bokhoven H, Schenck A, Kramer JM
PLoS Genet 2017 Oct;13(10):e1006864. Epub 2017 Oct 25 doi: 10.1371/journal.pgen.1006864. PMID: 29069077Free PMC Article
Classification and Current Management of Inner Ear Malformations.
Sennaroğlu L, Bajin MD
Balkan Med J 2017 Sep 29;34(5):397-411. Epub 2017 Aug 25 doi: 10.4274/balkanmedj.2017.0367. PMID: 28840850Free PMC Article
Moebius syndrome: clinical features, diagnosis, management and early intervention.
Picciolini O, Porro M, Cattaneo E, Castelletti S, Masera G, Mosca F, Bedeschi MF
Ital J Pediatr 2016 Jun 3;42(1):56. doi: 10.1186/s13052-016-0256-5. PMID: 27260152Free PMC Article
The facial tics.
Harrison MS
J Laryngol Otol 1976 Jun;90(6):561-70. doi: 10.1017/s0022215100082451. PMID: 778316

Diagnosis

Craniofacial Microsomia.
Birgfeld C, Heike C
Clin Plast Surg 2019 Apr;46(2):207-221. doi: 10.1016/j.cps.2018.12.001. PMID: 30851752
Moebius syndrome: clinical features, diagnosis, management and early intervention.
Picciolini O, Porro M, Cattaneo E, Castelletti S, Masera G, Mosca F, Bedeschi MF
Ital J Pediatr 2016 Jun 3;42(1):56. doi: 10.1186/s13052-016-0256-5. PMID: 27260152Free PMC Article
Binder syndrome.
Chummun S, McLean NR, Nugent M, Anderson PJ, David DJ
J Craniofac Surg 2012 Jul;23(4):986-90. doi: 10.1097/SCS.0b013e31824e2683. PMID: 22777437
Seventh cranial neuropathy.
Gilchrist JM
Semin Neurol 2009 Feb;29(1):5-13. Epub 2009 Feb 12 doi: 10.1055/s-0028-1124018. PMID: 19214928
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Therapy

TREATMENT OPTIONS FOR TRIGEMINAL NEURALGIA.
Radoš I
Acta Clin Croat 2022 Sep;61(Suppl 2):96-102. doi: 10.20471/acc.2022.61.s2.12. PMID: 36824641Free PMC Article
Trigeminal Neuralgia: Basic and Clinical Aspects.
Araya EI, Claudino RF, Piovesan EJ, Chichorro JG
Curr Neuropharmacol 2020;18(2):109-119. doi: 10.2174/1570159X17666191010094350. PMID: 31608834Free PMC Article
Congenital myasthenic syndromes.
Finsterer J
Orphanet J Rare Dis 2019 Feb 26;14(1):57. doi: 10.1186/s13023-019-1025-5. PMID: 30808424Free PMC Article
Guillain-Barré syndrome: clinical profile and management.
Sudulagunta SR, Sodalagunta MB, Sepehrar M, Khorram H, Bangalore Raja SK, Kothandapani S, Noroozpour Z, Aheta Sham M, Prasad N, Sunny SP, Mohammed MD, Gangadharappa R, Nidsale Sudarshan R
Ger Med Sci 2015;13:Doc16. Epub 2015 Sep 21 doi: 10.3205/000220. PMID: 26421004Free PMC Article
Bell's palsy: diagnosis and management.
Tiemstra JD, Khatkhate N
Am Fam Physician 2007 Oct 1;76(7):997-1002. PMID: 17956069

Prognosis

Clinical neurophysiology of cranial nerve disorders.
Kennelly KD
Handb Clin Neurol 2019;161:327-342. doi: 10.1016/B978-0-444-64142-7.00058-8. PMID: 31307611
Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder.
Koemans TS, Kleefstra T, Chubak MC, Stone MH, Reijnders MRF, de Munnik S, Willemsen MH, Fenckova M, Stumpel CTRM, Bok LA, Sifuentes Saenz M, Byerly KA, Baughn LB, Stegmann APA, Pfundt R, Zhou H, van Bokhoven H, Schenck A, Kramer JM
PLoS Genet 2017 Oct;13(10):e1006864. Epub 2017 Oct 25 doi: 10.1371/journal.pgen.1006864. PMID: 29069077Free PMC Article
Moebius syndrome: clinical features, diagnosis, management and early intervention.
Picciolini O, Porro M, Cattaneo E, Castelletti S, Masera G, Mosca F, Bedeschi MF
Ital J Pediatr 2016 Jun 3;42(1):56. doi: 10.1186/s13052-016-0256-5. PMID: 27260152Free PMC Article
Seventh cranial neuropathy.
Gilchrist JM
Semin Neurol 2009 Feb;29(1):5-13. Epub 2009 Feb 12 doi: 10.1055/s-0028-1124018. PMID: 19214928
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Clinical prediction guides

Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder.
Koemans TS, Kleefstra T, Chubak MC, Stone MH, Reijnders MRF, de Munnik S, Willemsen MH, Fenckova M, Stumpel CTRM, Bok LA, Sifuentes Saenz M, Byerly KA, Baughn LB, Stegmann APA, Pfundt R, Zhou H, van Bokhoven H, Schenck A, Kramer JM
PLoS Genet 2017 Oct;13(10):e1006864. Epub 2017 Oct 25 doi: 10.1371/journal.pgen.1006864. PMID: 29069077Free PMC Article
Classification and Current Management of Inner Ear Malformations.
Sennaroğlu L, Bajin MD
Balkan Med J 2017 Sep 29;34(5):397-411. Epub 2017 Aug 25 doi: 10.4274/balkanmedj.2017.0367. PMID: 28840850Free PMC Article
Guillain-Barré syndrome: clinical profile and management.
Sudulagunta SR, Sodalagunta MB, Sepehrar M, Khorram H, Bangalore Raja SK, Kothandapani S, Noroozpour Z, Aheta Sham M, Prasad N, Sunny SP, Mohammed MD, Gangadharappa R, Nidsale Sudarshan R
Ger Med Sci 2015;13:Doc16. Epub 2015 Sep 21 doi: 10.3205/000220. PMID: 26421004Free PMC Article
Congenital cataracts-facial dysmorphism-neuropathy.
Kalaydjieva L
Orphanet J Rare Dis 2006 Aug 29;1:32. doi: 10.1186/1750-1172-1-32. PMID: 16939648Free PMC Article
Oculonasal synkinesis.
Guyuron B, Bokhari F, Galloway DV, Thomas T
Plast Reconstr Surg 1994 Aug;94(2):251-3. doi: 10.1097/00006534-199408000-00005. PMID: 8041815

Recent systematic reviews

A systematic review and network meta-analysis of the effectiveness of sclerotherapy for venous malformation.
Cao J, Liu J, Zhang X, Wang Z
J Vasc Surg Venous Lymphat Disord 2023 Jan;11(1):210-218.e3. Epub 2022 Sep 28 doi: 10.1016/j.jvsv.2022.08.004. PMID: 36179784
Systematic review of CMTX1 patients with episodic neurological dysfunction.
Tian D, Zhao Y, Zhu R, Li Q, Liu X
Ann Clin Transl Neurol 2021 Jan;8(1):213-223. Epub 2020 Dec 12 doi: 10.1002/acn3.51271. PMID: 33314704Free PMC Article
Congenital myasthenic syndromes.
Finsterer J
Orphanet J Rare Dis 2019 Feb 26;14(1):57. doi: 10.1186/s13023-019-1025-5. PMID: 30808424Free PMC Article
Clinical features, treatment and outcome in neurosarcoidosis: systematic review and meta-analysis.
Fritz D, van de Beek D, Brouwer MC
BMC Neurol 2016 Nov 15;16(1):220. doi: 10.1186/s12883-016-0741-x. PMID: 27846819Free PMC Article
Sclerotherapy for low-flow vascular malformations of the head and neck: A systematic review of sclerosing agents.
Horbach SE, Lokhorst MM, Saeed P, de Goüyon Matignon de Pontouraude CM, Rothová A, van der Horst CM
J Plast Reconstr Aesthet Surg 2016 Mar;69(3):295-304. Epub 2015 Nov 18 doi: 10.1016/j.bjps.2015.10.045. PMID: 26723834

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