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Midshaft hypospadias

MedGen UID:
868314
•Concept ID:
C4022708
•
Anatomical Abnormality
HPO: HP:0012854

Definition

Hypospadias with location of the urethral meatus in the middle of the inferior shaft of the penis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMidshaft hypospadias

Professional guidelines

PubMed

Yield of modern genetic evaluation for patients with proximal hypospadias and descended gonads.
Rowe CK, Adam MP, Ahn JJ, Merguerian PA, Shnorhavorian M
J Pediatr Urol 2019 Oct;15(5):527.e1-527.e6. Epub 2019 Jul 27 doi: 10.1016/j.jpurol.2019.07.017. PMID: 31537436

Recent clinical studies

Etiology

Application and efficacy of reconstructing forked corpus spongiosum in distal/midshaft hypospadias repair.
Zhang B, Bi YL, Ruan SS
Asian J Androl 2021 Jan-Feb;23(1):47-51. doi: 10.4103/aja.aja_42_20. PMID: 32859871Free PMC Article
Perioperative complications within 30 days of hypospadias surgery: Results from NSQIP-Pediatrics.
Jiang DD, Chakiryan NH, Gillis KA, Acevedo AM, Austin JC, Seideman CA
J Pediatr Urol 2020 Jun;16(3):316.e1-316.e7. Epub 2020 Apr 6 doi: 10.1016/j.jpurol.2020.03.026. PMID: 32317234
Tubularized proximally-incised plate in distal/midshaft hypospadias repair.
Marte A, Pintozzi L
Pediatr Med Chir 2017 Jun 23;39(2):151. doi: 10.4081/pmc.2017.151. PMID: 28673072
Midshaft hypospadias.
Upadhyay J, Shekarriz B, Khoury AE
Urol Clin North Am 2002 May;29(2):299-310. doi: 10.1016/s0094-0143(02)00049-6. PMID: 12371222
Urethral mobilization and advancement for midshaft to distal hypospadias.
Atala A
J Urol 2002 Oct;168(4 Pt 2):1738-41; discussion 1741. doi: 10.1097/01.ju.0000023971.96439.b8. PMID: 12352348

Diagnosis

Yield of modern genetic evaluation for patients with proximal hypospadias and descended gonads.
Rowe CK, Adam MP, Ahn JJ, Merguerian PA, Shnorhavorian M
J Pediatr Urol 2019 Oct;15(5):527.e1-527.e6. Epub 2019 Jul 27 doi: 10.1016/j.jpurol.2019.07.017. PMID: 31537436
PCR and FISH analysis of a ring Y chromosome.
Henegariu O, Kernek S, Keating MA, Palmer CG, Heerema NA
Am J Med Genet 1997 Mar 17;69(2):171-6. doi: 10.1002/(sici)1096-8628(19970317)69:2<171::aid-ajmg11>3.0.co;2-i. PMID: 9056556

Therapy

Reconstructing forked corpus spongiosum to correct glans droop in distal/midshaft hypospadias repair.
Zhang B, Bi Y, Ruan S
J Int Med Res 2020 May;48(5):300060520925698. doi: 10.1177/0300060520925698. PMID: 32459109Free PMC Article
Perioperative complications within 30 days of hypospadias surgery: Results from NSQIP-Pediatrics.
Jiang DD, Chakiryan NH, Gillis KA, Acevedo AM, Austin JC, Seideman CA
J Pediatr Urol 2020 Jun;16(3):316.e1-316.e7. Epub 2020 Apr 6 doi: 10.1016/j.jpurol.2020.03.026. PMID: 32317234
Tunica vaginalis flap is superior to inner preputial dartos flap as a waterproofing layer for primary TIP repair in midshaft hypospadias.
Babu R, Hariharasudhan S
J Pediatr Urol 2013 Dec;9(6 Pt A):804-7. Epub 2012 Nov 25 doi: 10.1016/j.jpurol.2012.10.022. PMID: 23186594
Para-meatus skin incision with long channel technique for midshaft hypospadias repair without penile curvature.
Su C, Yang T, Zhang Z, Xu Y, Liang Q
Urology 2012 May;79(5):1143-8. Epub 2012 Feb 4 doi: 10.1016/j.urology.2011.11.034. PMID: 22305761
Primary and reoperative hypospadias repair with the Snodgrass technique.
Retik AB, Borer JG
World J Urol 1998;16(3):186-91. doi: 10.1007/s003450050050. PMID: 9666542

Prognosis

Reconstructing forked corpus spongiosum to correct glans droop in distal/midshaft hypospadias repair.
Zhang B, Bi Y, Ruan S
J Int Med Res 2020 May;48(5):300060520925698. doi: 10.1177/0300060520925698. PMID: 32459109Free PMC Article
Yield of modern genetic evaluation for patients with proximal hypospadias and descended gonads.
Rowe CK, Adam MP, Ahn JJ, Merguerian PA, Shnorhavorian M
J Pediatr Urol 2019 Oct;15(5):527.e1-527.e6. Epub 2019 Jul 27 doi: 10.1016/j.jpurol.2019.07.017. PMID: 31537436
Tubularized proximally-incised plate in distal/midshaft hypospadias repair.
Marte A, Pintozzi L
Pediatr Med Chir 2017 Jun 23;39(2):151. doi: 10.4081/pmc.2017.151. PMID: 28673072
Urethral mobilization and advancement for midshaft to distal hypospadias.
Atala A
J Urol 2002 Oct;168(4 Pt 2):1738-41; discussion 1741. doi: 10.1097/01.ju.0000023971.96439.b8. PMID: 12352348
Tubularized incised-plate urethroplasty for hypospadias reoperation.
Snodgrass WT, Lorenzo A
BJU Int 2002 Jan;89(1):98-100. doi: 10.1046/j.1464-4096.2001.01688.x. PMID: 11849171

Clinical prediction guides

The modified Belt-Fuqua procedure using an asymmetric "furisode" sleeve for proximal hypospadias with severe curvature.
Yamazaki Y, Nishi M, Shimokihara K, Eura R, Gohbara A
J Pediatr Urol 2022 Jun;18(3):365.e1-365.e8. Epub 2022 Mar 22 doi: 10.1016/j.jpurol.2022.03.013. PMID: 35382983
Reconstructing forked corpus spongiosum to correct glans droop in distal/midshaft hypospadias repair.
Zhang B, Bi Y, Ruan S
J Int Med Res 2020 May;48(5):300060520925698. doi: 10.1177/0300060520925698. PMID: 32459109Free PMC Article
Standard Snodgrass technique in conjunction with double-layer covering of the neourethra with dorsal dartos flap is the therapy of first choice for hypospadias.
Mustafa M, Wadie BS, Abol-Enein H
Int Urol Nephrol 2008;40(3):573-6. Epub 2008 Mar 8 doi: 10.1007/s11255-008-9363-6. PMID: 18327654

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