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Esophageal disorder

MedGen UID:
8693
•Concept ID:
C0014852
•
Disease or Syndrome
Synonym: Esophageal disease
SNOMED CT: Disorder of esophagus (37657006)
 
Monarch Initiative: MONDO:0003749

Definition

A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEsophageal disorder

Professional guidelines

PubMed

Eosinophilic Esophagitis: Clinical Pearls for Primary Care Providers and Gastroenterologists.
Goyal R, Kamboj AK, Snyder DL
Mayo Clin Proc 2024 Apr;99(4):640-648. doi: 10.1016/j.mayocp.2023.12.026. PMID: 38569813
Noncardiac chest pain: update on the diagnosis and management.
Min YW, Rhee PL
Korean J Gastroenterol 2015 Feb;65(2):76-84. doi: 10.4166/kjg.2015.65.2.76. PMID: 25716709
Achalasia: an overview of diagnosis and treatment.
Pohl D, Tutuian R
J Gastrointestin Liver Dis 2007 Sep;16(3):297-303. PMID: 17925926

Recent clinical studies

Etiology

Functional Food in Relation to Gastroesophageal Reflux Disease (GERD).
Herdiana Y
Nutrients 2023 Aug 15;15(16) doi: 10.3390/nu15163583. PMID: 37630773Free PMC Article
The 2018 ISDE achalasia guidelines.
Zaninotto G, Bennett C, Boeckxstaens G, Costantini M, Ferguson MK, Pandolfino JE, Patti MG, Ribeiro U Jr, Richter J, Swanstrom L, Tack J, Triadafilopoulos G, Markar SR, Salvador R, Faccio L, Andreollo NA, Cecconello I, Costamagna G, da Rocha JRM, Hungness ES, Fisichella PM, Fuchs KH, Gockel I, Gurski R, Gyawali CP, Herbella FAM, Holloway RH, Hongo M, Jobe BA, Kahrilas PJ, Katzka DA, Dua KS, Liu D, Moonen A, Nasi A, Pasricha PJ, Penagini R, Perretta S, Sallum RAA, Sarnelli G, Savarino E, Schlottmann F, Sifrim D, Soper N, Tatum RP, Vaezi MF, van Herwaarden-Lindeboom M, Vanuytsel T, Vela MF, Watson DI, Zerbib F, Gittens S, Pontillo C, Vermigli S, Inama D, Low DE
Dis Esophagus 2018 Sep 1;31(9) doi: 10.1093/dote/doy071. PMID: 30169645
The Role of Esophageal Hypersensitivity in Functional Heartburn.
Kondo T, Miwa H
J Clin Gastroenterol 2017 Aug;51(7):571-578. doi: 10.1097/MCG.0000000000000885. PMID: 28682989
White Paper AGA: Drug Development for Eosinophilic Esophagitis.
Hirano I, Spechler S, Furuta G, Dellon ES
Clin Gastroenterol Hepatol 2017 Aug;15(8):1173-1183. Epub 2017 Mar 22 doi: 10.1016/j.cgh.2017.03.016. PMID: 28342955Free PMC Article
Eosinophilic esophagitis: an autoimmune esophageal disorder.
Malhotra N, Levine J
Curr Probl Pediatr Adolesc Health Care 2014 Dec;44(11):335-40. doi: 10.1016/j.cppeds.2014.10.004. PMID: 25499460

Diagnosis

Genetic and Molecular Contributors in Eosinophilic Esophagitis.
Sato H, Osonoi K, Sharlin CS, Shoda T
Curr Allergy Asthma Rep 2023 May;23(5):255-266. Epub 2023 Apr 21 doi: 10.1007/s11882-023-01075-0. PMID: 37084008
Robotic Surgery in Achalasia: State of the Art.
Palomba G, Capuano M, Basile R, Sorrentino G, Fernicola A, Anoldo P, Milone M, De GD, Aprea G
Chirurgia (Bucur) 2023 Feb;118(1):8-19. doi: 10.21614/chirurgia.2830. PMID: 36913413
Nonerosive reflux disease: clinical concepts.
Gyawali CP, Azagury DE, Chan WW, Chandramohan SM, Clarke JO, de Bortoli N, Figueredo E, Fox M, Jodorkovsky D, Lazarescu A, Malfertheiner P, Martinek J, Murayama KM, Penagini R, Savarino E, Shetler KP, Stein E, Tatum RP, Wu J
Ann N Y Acad Sci 2018 Dec;1434(1):290-303. Epub 2018 May 15 doi: 10.1111/nyas.13845. PMID: 29761528
The Role of Esophageal Hypersensitivity in Functional Heartburn.
Kondo T, Miwa H
J Clin Gastroenterol 2017 Aug;51(7):571-578. doi: 10.1097/MCG.0000000000000885. PMID: 28682989
Functional disorders of swallowing.
Baumann A, Katz PO
Handb Clin Neurol 2016;139:483-488. doi: 10.1016/B978-0-12-801772-2.00039-4. PMID: 27719865

Therapy

Robotic Surgery in Achalasia: State of the Art.
Palomba G, Capuano M, Basile R, Sorrentino G, Fernicola A, Anoldo P, Milone M, De GD, Aprea G
Chirurgia (Bucur) 2023 Feb;118(1):8-19. doi: 10.21614/chirurgia.2830. PMID: 36913413
The 2018 ISDE achalasia guidelines.
Zaninotto G, Bennett C, Boeckxstaens G, Costantini M, Ferguson MK, Pandolfino JE, Patti MG, Ribeiro U Jr, Richter J, Swanstrom L, Tack J, Triadafilopoulos G, Markar SR, Salvador R, Faccio L, Andreollo NA, Cecconello I, Costamagna G, da Rocha JRM, Hungness ES, Fisichella PM, Fuchs KH, Gockel I, Gurski R, Gyawali CP, Herbella FAM, Holloway RH, Hongo M, Jobe BA, Kahrilas PJ, Katzka DA, Dua KS, Liu D, Moonen A, Nasi A, Pasricha PJ, Penagini R, Perretta S, Sallum RAA, Sarnelli G, Savarino E, Schlottmann F, Sifrim D, Soper N, Tatum RP, Vaezi MF, van Herwaarden-Lindeboom M, Vanuytsel T, Vela MF, Watson DI, Zerbib F, Gittens S, Pontillo C, Vermigli S, Inama D, Low DE
Dis Esophagus 2018 Sep 1;31(9) doi: 10.1093/dote/doy071. PMID: 30169645
White Paper AGA: Drug Development for Eosinophilic Esophagitis.
Hirano I, Spechler S, Furuta G, Dellon ES
Clin Gastroenterol Hepatol 2017 Aug;15(8):1173-1183. Epub 2017 Mar 22 doi: 10.1016/j.cgh.2017.03.016. PMID: 28342955Free PMC Article
Molecular pathogenesis of eosinophilic esophagitis.
Blanchard C
Curr Opin Gastroenterol 2015 Jul;31(4):321-7. doi: 10.1097/MOG.0000000000000186. PMID: 26039724
Odynophagia/dysphagia in AIDS.
Raufman JP
Gastroenterol Clin North Am 1988 Sep;17(3):599-614. PMID: 3049365

Prognosis

Gastroesophageal Reflux and Esophageal Motility Disorder After Lung Transplant: Influence on the Transplanted Graft.
de Pablo A, Alonso R, Ciriza C, Lopez E, Canga F, Juarros L, Gamez P, Perez V
Transplant Proc 2021 Jul-Aug;53(6):1989-1997. Epub 2021 May 14 doi: 10.1016/j.transproceed.2021.03.035. PMID: 33994181
Eosinophilic esophagitis: an autoimmune esophageal disorder.
Malhotra N, Levine J
Curr Probl Pediatr Adolesc Health Care 2014 Dec;44(11):335-40. doi: 10.1016/j.cppeds.2014.10.004. PMID: 25499460
Achalasia: an overview of diagnosis and treatment.
Pohl D, Tutuian R
J Gastrointestin Liver Dis 2007 Sep;16(3):297-303. PMID: 17925926
A critical approach to noncardiac chest pain: pathophysiology, diagnosis, and treatment.
Fang J, Bjorkman D
Am J Gastroenterol 2001 Apr;96(4):958-68. doi: 10.1111/j.1572-0241.2001.03678.x. PMID: 11316212
Duodenogastro-oesophageal reflux.
Vaezi MF, Richter JE
Baillieres Best Pract Res Clin Gastroenterol 2000 Oct;14(5):719-29. doi: 10.1053/bega.2000.0120. PMID: 11003805

Clinical prediction guides

Robotic Surgery in Achalasia: State of the Art.
Palomba G, Capuano M, Basile R, Sorrentino G, Fernicola A, Anoldo P, Milone M, De GD, Aprea G
Chirurgia (Bucur) 2023 Feb;118(1):8-19. doi: 10.21614/chirurgia.2830. PMID: 36913413
Gastroesophageal Reflux and Esophageal Motility Disorder After Lung Transplant: Influence on the Transplanted Graft.
de Pablo A, Alonso R, Ciriza C, Lopez E, Canga F, Juarros L, Gamez P, Perez V
Transplant Proc 2021 Jul-Aug;53(6):1989-1997. Epub 2021 May 14 doi: 10.1016/j.transproceed.2021.03.035. PMID: 33994181
Esophageal foreign bodies: observational cohort study and factors associated with recurrent impaction.
Ferrari D, Siboni S, Riva CG, Aiolfi A, Panici Tonucci T, Asti E, Bonavina L
Eur J Gastroenterol Hepatol 2020 Jul;32(7):827-831. doi: 10.1097/MEG.0000000000001717. PMID: 32243348
The assessment of the esophageal motility of children with esophageal disorders by the detailed observation of the pH-multichannel intraluminal impedance waveform and baseline impedance: screening test potential.
Masui D, Fukahori S, Ishii S, Hashizume N, Saikusa N, Yoshida M, Higashidate N, Sakamoto S, Tsuruhisa S, Nakahara H, Tanaka Y, Yagi M
Esophagus 2019 Apr;16(2):133-140. Epub 2018 Aug 25 doi: 10.1007/s10388-018-0640-x. PMID: 30145680
Eosinophilic esophagitis: an autoimmune esophageal disorder.
Malhotra N, Levine J
Curr Probl Pediatr Adolesc Health Care 2014 Dec;44(11):335-40. doi: 10.1016/j.cppeds.2014.10.004. PMID: 25499460

Recent systematic reviews

Radiation burden in patients with esophageal atresia: a systematic review.
Comella A, Tan Tanny SP, Hutson JM, Omari TI, Teague WJ, Nataraja RM, King SK
Pediatr Surg Int 2021 Jul;37(7):919-927. Epub 2021 Apr 10 doi: 10.1007/s00383-021-04892-4. PMID: 33839909
PERORAL (POEM) OR SURGICAL MYOTOMY FOR THE TREATMENT OF ACHALASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Martins RK, Ribeiro IB, DE Moura DTH, Hathorn KE, Bernardo WM, DE Moura EGH
Arq Gastroenterol 2020 Jan-Mar;57(1):79-86. doi: 10.1590/S0004-2803.202000000-14. PMID: 32294740
Natural history of eosinophilic esophagitis: a systematic review of epidemiology and disease course.
Shaheen NJ, Mukkada V, Eichinger CS, Schofield H, Todorova L, Falk GW
Dis Esophagus 2018 Aug 1;31(8) doi: 10.1093/dote/doy015. PMID: 29617744Free PMC Article

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