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Chronic hepatic encephalopathy

MedGen UID:
870490
•Concept ID:
C4024937
•
Disease or Syndrome
HPO: HP:0007111

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic hepatic encephalopathy

Conditions with this feature

Splenoportal vascular anomaly
MedGen UID:
137945
•Concept ID:
C0340826
•
Congenital Abnormality
See: Condition Record
Splenoportal vascular anomaly

Professional guidelines

PubMed

Contemporary management of pain in cirrhosis: Toward precision therapy for pain.
Holman A, Parikh N, Clauw DJ, Williams DA, Tapper EB
Hepatology 2023 Jan 1;77(1):290-304. Epub 2022 Jul 6 doi: 10.1002/hep.32598. PMID: 35665522Free PMC Article
Pathophysiology, diagnosis and treatment of ascites in cirrhosis.
Arroyo V
Ann Hepatol 2002 Apr-Jun;1(2):72-9. PMID: 15115971
The treatment of chronic hepatic encephalopathy.
Morgan MY
Hepatogastroenterology 1991 Oct;38(5):377-87. PMID: 1662661

Recent clinical studies

Etiology

Probiotics for people with hepatic encephalopathy.
Dalal R, McGee RG, Riordan SM, Webster AC
Cochrane Database Syst Rev 2017 Feb 23;2(2):CD008716. doi: 10.1002/14651858.CD008716.pub3. PMID: 28230908Free PMC Article
Probiotics for patients with hepatic encephalopathy.
McGee RG, Bakens A, Wiley K, Riordan SM, Webster AC
Cochrane Database Syst Rev 2011 Nov 9;(11):CD008716. doi: 10.1002/14651858.CD008716.pub2. PMID: 22071855
Rifaximin versus nonabsorbable disaccharides in the management of hepatic encephalopathy: a meta-analysis.
Jiang Q, Jiang XH, Zheng MH, Jiang LM, Chen YP, Wang L
Eur J Gastroenterol Hepatol 2008 Nov;20(11):1064-70. doi: 10.1097/MEG.0b013e328302f470. PMID: 19047837
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160
Overview of randomized clinical trials of oral branched-chain amino acid treatment in chronic hepatic encephalopathy.
Fabbri A, Magrini N, Bianchi G, Zoli M, Marchesini G
JPEN J Parenter Enteral Nutr 1996 Mar-Apr;20(2):159-64. doi: 10.1177/0148607196020002159. PMID: 8676537

Diagnosis

Study on Precipitating Factor of Chronic Hepatic Encephalopathy.
Ali MH, Kabir MA, Islam MS, Rahim CM, Hasan MK, Islam MK, Hasan MR, Alam MS
Mymensingh Med J 2020 Oct;29(4):800-806. PMID: 33116080
Wernicke encephalopathy and ethanol-related syndromes.
Kim TE, Lee EJ, Young JB, Shin DJ, Kim JH
Semin Ultrasound CT MR 2014 Apr;35(2):85-96. doi: 10.1053/j.sult.2013.09.004. PMID: 24745886
Pathophysiology, diagnosis and treatment of ascites in cirrhosis.
Arroyo V
Ann Hepatol 2002 Apr-Jun;1(2):72-9. PMID: 15115971
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160
Manganese and chronic hepatic encephalopathy.
Krieger D, Krieger S, Jansen O, Gass P, Theilmann L, Lichtnecker H
Lancet 1995 Jul 29;346(8970):270-4. doi: 10.1016/s0140-6736(95)92164-8. PMID: 7630246

Therapy

Probiotics for people with hepatic encephalopathy.
Dalal R, McGee RG, Riordan SM, Webster AC
Cochrane Database Syst Rev 2017 Feb 23;2(2):CD008716. doi: 10.1002/14651858.CD008716.pub3. PMID: 28230908Free PMC Article
Wernicke encephalopathy and ethanol-related syndromes.
Kim TE, Lee EJ, Young JB, Shin DJ, Kim JH
Semin Ultrasound CT MR 2014 Apr;35(2):85-96. doi: 10.1053/j.sult.2013.09.004. PMID: 24745886
Pathophysiology, diagnosis and treatment of ascites in cirrhosis.
Arroyo V
Ann Hepatol 2002 Apr-Jun;1(2):72-9. PMID: 15115971
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160
Review article: pathogenesis and treatment of chronic hepatic encephalopathy.
Jalan R, Seery JP, Taylor-Robinson SD
Aliment Pharmacol Ther 1996 Oct;10(5):681-97. doi: 10.1046/j.1365-2036.1996.58200000.x. PMID: 8899075

Prognosis

Probiotics for people with hepatic encephalopathy.
Dalal R, McGee RG, Riordan SM, Webster AC
Cochrane Database Syst Rev 2017 Feb 23;2(2):CD008716. doi: 10.1002/14651858.CD008716.pub3. PMID: 28230908Free PMC Article
Pathophysiology, diagnosis and treatment of ascites in cirrhosis.
Arroyo V
Ann Hepatol 2002 Apr-Jun;1(2):72-9. PMID: 15115971
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160
Relationship between pre-TIPS liver perfusion by the portal vein and the incidence of post-TIPS chronic hepatic encephalopathy.
Hassoun Z, Deschênes M, Lafortune M, Dufresne MP, Perreault P, Lepanto L, Gianfelice D, Bui B, Pomier-Layrargues G
Am J Gastroenterol 2001 Apr;96(4):1205-9. doi: 10.1111/j.1572-0241.2001.03704.x. PMID: 11316171
Factors predicting chronic hepatic encephalopathy after distal splenorenal shunt: a multivariate analysis of clinical and hemodynamic variables.
Spina GP, Santambrogio R, Opocher E, Pisani-Ceretti A, Ongari B, Rashidi B, Garancini P, Gallus G
Surgery 1993 Sep;114(3):519-26. PMID: 8367806

Clinical prediction guides

Oral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled double-blind study.
Stauch S, Kircheis G, Adler G, Beckh K, Ditschuneit H, Görtelmeyer R, Hendricks R, Heuser A, Karoff C, Malfertheiner P, Mayer D, Rösch W, Steffens J
J Hepatol 1998 May;28(5):856-64. doi: 10.1016/s0168-8278(98)80237-7. PMID: 9625322
Overview of randomized clinical trials of oral branched-chain amino acid treatment in chronic hepatic encephalopathy.
Fabbri A, Magrini N, Bianchi G, Zoli M, Marchesini G
JPEN J Parenter Enteral Nutr 1996 Mar-Apr;20(2):159-64. doi: 10.1177/0148607196020002159. PMID: 8676537
Manganese and chronic hepatic encephalopathy.
Krieger D, Krieger S, Jansen O, Gass P, Theilmann L, Lichtnecker H
Lancet 1995 Jul 29;346(8970):270-4. doi: 10.1016/s0140-6736(95)92164-8. PMID: 7630246
Factors predicting chronic hepatic encephalopathy after distal splenorenal shunt: a multivariate analysis of clinical and hemodynamic variables.
Spina GP, Santambrogio R, Opocher E, Pisani-Ceretti A, Ongari B, Rashidi B, Garancini P, Gallus G
Surgery 1993 Sep;114(3):519-26. PMID: 8367806
Lactitol in the treatment of chronic hepatic encephalopathy--a randomized cross-over comparison with lactulose.
Riggio O, Balducci G, Ariosto F, Merli M, Tremiterra S, Ziparo V, Capocaccia L
Hepatogastroenterology 1990 Oct;37(5):524-7. PMID: 2253931

Recent systematic reviews

Portosystemic shunts versus endoscopic intervention with or without medical treatment for prevention of rebleeding in people with cirrhosis.
Simonetti RG, Perricone G, Robbins HL, Battula NR, Weickert MO, Sutton R, Khan S
Cochrane Database Syst Rev 2020 Oct 22;10(10):CD000553. doi: 10.1002/14651858.CD000553.pub3. PMID: 33089892Free PMC Article
Probiotics for people with hepatic encephalopathy.
Dalal R, McGee RG, Riordan SM, Webster AC
Cochrane Database Syst Rev 2017 Feb 23;2(2):CD008716. doi: 10.1002/14651858.CD008716.pub3. PMID: 28230908Free PMC Article
Probiotics for patients with hepatic encephalopathy.
McGee RG, Bakens A, Wiley K, Riordan SM, Webster AC
Cochrane Database Syst Rev 2011 Nov 9;(11):CD008716. doi: 10.1002/14651858.CD008716.pub2. PMID: 22071855
Dopaminergic agonists for hepatic encephalopathy.
Als-Nielsen B, Gluud LL, Gluud C
Cochrane Database Syst Rev 2004 Oct 18;(4):CD003047. doi: 10.1002/14651858.CD003047.pub2. PMID: 15495041
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160

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