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Diffuse cerebral calcification

MedGen UID:
870671
Concept ID:
C4025125
Finding
HPO: HP:0005849

Definition

Generalized deposition of calcium salts within the cerebrum. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiffuse cerebral calcification

Professional guidelines

PubMed

Nakamura Y, Nishijima S, Kuroda M, Nakayama T, Tsuruta R, Yoshiyama D, Yasumoto Y, Ito Y
Eur J Cardiothorac Surg 2021 Jun 14;59(6):1200-1207. doi: 10.1093/ejcts/ezaa469. PMID: 33448282
Lundy P, Domino J, Ryken T, Fouke S, McCracken DJ, Ormond DR, Olson JJ
J Neurooncol 2020 Nov;150(2):95-120. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03597-3. PMID: 33215340
Eskreis-Winkler S, Zhang Y, Zhang J, Liu Z, Dimov A, Gupta A, Wang Y
NMR Biomed 2017 Apr;30(4) Epub 2016 Dec 1 doi: 10.1002/nbm.3668. PMID: 27906525

Recent clinical studies

Etiology

Hashimoto Y, Greene C, Munnich A, Campbell M
Fluids Barriers CNS 2023 Mar 28;20(1):22. doi: 10.1186/s12987-023-00424-5. PMID: 36978081Free PMC Article
Alves IS, Coutinho AMN, Vieira APF, Rocha BP, Passos UL, Gonçalves VT, Silva PDS, Zhan MX, Pinho PC, Delgado DS, Docema MFL, Lee HW, Policeni BA, Leite CC, Martin MGM, Amancio CT
Radiographics 2022 May-Jun;42(3):822-840. Epub 2022 Feb 25 doi: 10.1148/rg.210153. PMID: 35213261
Ashrafi MR, Amanat M, Garshasbi M, Kameli R, Nilipour Y, Heidari M, Rezaei Z, Tavasoli AR
Expert Rev Neurother 2020 Jan;20(1):65-84. Epub 2019 Dec 12 doi: 10.1080/14737175.2020.1699060. PMID: 31829048
Diogo MC, Glatter S, Binder J, Kiss H, Prayer D
Prenat Diagn 2020 Jan;40(1):110-124. Epub 2020 Jan 6 doi: 10.1002/pd.5591. PMID: 31802515Free PMC Article
Epps RE, Pittelkow MR, Su WP
Semin Dermatol 1995 Jun;14(2):179-86. doi: 10.1016/s1085-5629(05)80016-1. PMID: 7640200

Diagnosis

Mandal AKJ, Patel NB, Missouris CG
Am J Med Sci 2020 Oct;360(4):406-409. Epub 2020 May 21 doi: 10.1016/j.amjms.2020.05.023. PMID: 32593413
Masselli G, Vaccaro Notte MR, Zacharzewska-Gondek A, Laghi F, Manganaro L, Brunelli R
Clin Radiol 2020 Aug;75(8):640.e1-640.e11. Epub 2020 Apr 26 doi: 10.1016/j.crad.2020.03.035. PMID: 32349872
Ashrafi MR, Amanat M, Garshasbi M, Kameli R, Nilipour Y, Heidari M, Rezaei Z, Tavasoli AR
Expert Rev Neurother 2020 Jan;20(1):65-84. Epub 2019 Dec 12 doi: 10.1080/14737175.2020.1699060. PMID: 31829048
Saigal G, Nagornaya N, Post MJD
Handb Clin Neurol 2016;135:365-397. doi: 10.1016/B978-0-444-53485-9.00019-2. PMID: 27432675
Epps RE, Pittelkow MR, Su WP
Semin Dermatol 1995 Jun;14(2):179-86. doi: 10.1016/s1085-5629(05)80016-1. PMID: 7640200

Therapy

Murthy SB, Zhang C, Shah S, Schwamm LH, Fonarow GC, Smith EE, Bhatt DL, Ziai WC, Kamel H, Sheth KN
Stroke 2023 Dec;54(12):2972-2980. Epub 2023 Nov 9 doi: 10.1161/STROKEAHA.123.043194. PMID: 37942641Free PMC Article
Du H, Zheng J, Li X, Bos D, Yang W, Cheng Y, Liu C, Wong LKS, Hu J, Chen X
Ann Clin Transl Neurol 2023 Jun;10(6):974-982. Epub 2023 Apr 23 doi: 10.1002/acn3.51780. PMID: 37088543Free PMC Article
Helman G, Viaene AN, Takanohashi A, Breur M, Berger R, Woidill S, Cottrell JR, Schiffmann R, Crow YJ, Simons C, Bugiani M, Vanderver A
J Child Neurol 2021 Feb;36(2):133-140. Epub 2020 Sep 28 doi: 10.1177/0883073820958330. PMID: 32988269
Mandal AKJ, Patel NB, Missouris CG
Am J Med Sci 2020 Oct;360(4):406-409. Epub 2020 May 21 doi: 10.1016/j.amjms.2020.05.023. PMID: 32593413
Epps RE, Pittelkow MR, Su WP
Semin Dermatol 1995 Jun;14(2):179-86. doi: 10.1016/s1085-5629(05)80016-1. PMID: 7640200

Prognosis

Auffret L, Ajlil Y, Tauziède-Espariat A, Kergrohen T, Puiseux C, Riffaud L, Blouin P, Bertozzi AI, Leblond P, Blomgren K, Froelich S, Picca A, Touat M, Sanson M, Beccaria K, Blauwblomme T, Dangouloff-Ros V, Boddaert N, Varlet P, Debily MA, Grill J, Castel D
Acta Neuropathol 2023 Dec 8;147(1):2. doi: 10.1007/s00401-023-02651-4. PMID: 38066305Free PMC Article
Du H, Zheng J, Li X, Bos D, Yang W, Cheng Y, Liu C, Wong LKS, Hu J, Chen X
Ann Clin Transl Neurol 2023 Jun;10(6):974-982. Epub 2023 Apr 23 doi: 10.1002/acn3.51780. PMID: 37088543Free PMC Article
Helman G, Viaene AN, Takanohashi A, Breur M, Berger R, Woidill S, Cottrell JR, Schiffmann R, Crow YJ, Simons C, Bugiani M, Vanderver A
J Child Neurol 2021 Feb;36(2):133-140. Epub 2020 Sep 28 doi: 10.1177/0883073820958330. PMID: 32988269
Diogo MC, Glatter S, Binder J, Kiss H, Prayer D
Prenat Diagn 2020 Jan;40(1):110-124. Epub 2020 Jan 6 doi: 10.1002/pd.5591. PMID: 31802515Free PMC Article
Xu L, Ouyang Z, Wang J, Liu Z, Fang J, Du J, He Y, Li G
J Neurooncol 2017 Mar;132(1):75-82. Epub 2016 Nov 18 doi: 10.1007/s11060-016-2336-1. PMID: 27864704

Clinical prediction guides

Du H, Zheng J, Li X, Bos D, Yang W, Cheng Y, Liu C, Wong LKS, Hu J, Chen X
Ann Clin Transl Neurol 2023 Jun;10(6):974-982. Epub 2023 Apr 23 doi: 10.1002/acn3.51780. PMID: 37088543Free PMC Article
Onishi S, Amatya VJ, Kolakshyapati M, Takano M, Yonezawa U, Taguchi A, Kaichi Y, Takeshima Y, Awai K, Sugiyama K, Kurisu K, Yamasaki F
Eur J Radiol 2020 May;126:108924. Epub 2020 Mar 2 doi: 10.1016/j.ejrad.2020.108924. PMID: 32193035
Gao L, Han F, Jin Y, Xiong J, Lv Y, Yao Z, Zhang J
Clin Radiol 2018 Mar;73(3):275-282. Epub 2017 Nov 13 doi: 10.1016/j.crad.2017.10.011. PMID: 29146003
Yadav N, Rao S, Saini J, Prasad C, Mahadevan A, Sadashiva N
Eur J Radiol 2017 Dec;97:44-52. Epub 2017 Oct 5 doi: 10.1016/j.ejrad.2017.10.004. PMID: 29153366
Bekiesinska-Figatowska M, Mierzewska H, Jurkiewicz E
Eur J Radiol 2013 May;82(5):837-49. Epub 2013 Jan 10 doi: 10.1016/j.ejrad.2012.12.006. PMID: 23313708

Recent systematic reviews

Donofrio CA, Bertazzoni G, Riccio L, Pinacoli A, Pianta L, Generali D, Ungari M, Servadei F, Roncaroli F, Fioravanti A
World Neurosurg 2024 Feb;182:83-90. Epub 2023 Nov 22 doi: 10.1016/j.wneu.2023.11.057. PMID: 37995988
Mickeviciute GC, Valiuskyte M, Plattén M, Wszolek ZK, Andersen O, Danylaité Karrenbauer V, Ineichen BV, Granberg T
J Intern Med 2022 Mar;291(3):269-282. Epub 2021 Dec 22 doi: 10.1111/joim.13420. PMID: 34875121
Lundy P, Domino J, Ryken T, Fouke S, McCracken DJ, Ormond DR, Olson JJ
J Neurooncol 2020 Nov;150(2):95-120. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03597-3. PMID: 33215340
Cunningham DA, Lowe LH, Shao L, Acosta NR
Pediatr Radiol 2016 Aug;46(9):1301-8. Epub 2016 Apr 5 doi: 10.1007/s00247-016-3607-x. PMID: 27048363
Fouke SJ, Benzinger T, Gibson D, Ryken TC, Kalkanis SN, Olson JJ
J Neurooncol 2015 Dec;125(3):457-79. Epub 2015 Nov 3 doi: 10.1007/s11060-015-1908-9. PMID: 26530262

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