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Spina bifida occulta at L5

MedGen UID:
870848
•Concept ID:
C4025308
•
Congenital Abnormality
HPO: HP:0004601

Definition

The closed form of spina bifida with incomplete closure of the vertebra L5 with intact overlying skin. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSpina bifida occulta at L5

Conditions with this feature

Acropectorovertebral dysplasia
MedGen UID:
400262
•Concept ID:
C1863307
•
Disease or Syndrome
Acropectorovertebral dysgenesis, or F syndrome, is an autosomal dominant skeletal dysplasia characterized by carpal and tarsal synostoses, syndactyly between the first and second fingers, hypodactyly and polydactyly of feet, and abnormalities of the sternum and spine (summary by Thiele et al., 2004).
See: Condition Record
Acropectorovertebral dysplasia

Professional guidelines

PubMed

Factors associated with failure of bony union after conservative treatment of acute cases of unilateral lumbar spondylolysis.
Tatsumura M, Gamada H, Okuwaki S, Eto F, Nagashima K, Ogawa T, Mammoto T, Hirano A, Koda M, Yamazaki M
BMC Musculoskelet Disord 2021 Jan 13;22(1):75. doi: 10.1186/s12891-020-03940-9. PMID: 33441118Free PMC Article
The adverse influence of spina bifida occulta on the medical treatment outcome of primary monosymptomatic nocturnal enuresis.
Cakiroglu B, Tas T, Eyyupoglu SE, Hazar AI, Can Balcı MB, Nas Y, Yilmazer F, Aksoy SH
Arch Ital Urol Androl 2014 Dec 30;86(4):270-3. doi: 10.4081/aiua.2014.4.270. PMID: 25641449

Recent clinical studies

Etiology

Characteristics of lumbar spondylolysis: L5 versus non-L5.
Gamada H, Tatsumura M, Okuwaki S, Asai R, Funayama T, Yamazaki M
BMC Musculoskelet Disord 2024 Jan 12;25(1):55. doi: 10.1186/s12891-024-07190-x. PMID: 38216892Free PMC Article
The effect of transitional vertebrae and spina bifida occulta on disc herniation, disc degeneration, and end-plate changes in pediatric patients with low back pain.
Illeez OG, Ulger FEB, Aktas I
Acta Orthop Belg 2022 Jun;88(2):275-283. doi: 10.52628/88.2.8528. PMID: 36001833
Distribution and imaging characteristics of spina bifida occulta in young people with low back pain: a retrospective cross-sectional study.
Li W, Xiong Z, Dong C, Song J, Zhang L, Zhou J, Wang Y, Yi P, Yang F, Tang X, Tan M
J Orthop Surg Res 2021 Feb 22;16(1):151. doi: 10.1186/s13018-021-02285-w. PMID: 33618758Free PMC Article
Spina bifida occulta: not to be overlooked in children with nocturnal enuresis.
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087
Prevalence and patterns of spina bifida occulta in 2707 normal adults.
Fidas A, MacDonald HL, Elton RA, Wild SR, Chisholm GD, Scott R
Clin Radiol 1987 Sep;38(5):537-42. doi: 10.1016/s0009-9260(87)80150-2. PMID: 3311565

Diagnosis

Characteristics and diagnostic factors associated with fresh lumbar spondylolysis in elementary school-aged children.
Tsukagoshi Y, Kamegaya M, Tatsumura M, Tomaru Y, Kamada H, Morita M, Saisu T, Nomura S, Ikezawa Y, Yamazaki M
Eur Spine J 2020 Oct;29(10):2465-2469. Epub 2020 Jul 31 doi: 10.1007/s00586-020-06553-x. PMID: 32737580
Characteristics of lumbar spondylolysis in elementary school age children.
Sakai T, Goda Y, Tezuka F, Takata Y, Higashino K, Sato M, Mase Y, Nagamachi A, Sairyo K
Eur Spine J 2016 Feb;25(2):602-6. Epub 2015 May 26 doi: 10.1007/s00586-015-4029-4. PMID: 26006706
Spina bifida occulta in high grade spondylolisthesis.
Babbi L, Terzi S, Bandiera S, Barbanti Brodano G
Eur Rev Med Pharmacol Sci 2014;18(1 Suppl):8-14. PMID: 24825035
Spina bifida occulta: not to be overlooked in children with nocturnal enuresis.
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087
Adult diastematomyelia.
Linn RM, Ford LT
Spine (Phila Pa 1976) 1994 Apr 1;19(7):852-4. doi: 10.1097/00007632-199404000-00024. PMID: 8202809

Therapy

Migration of a ventriculo-peritoneal shunt catheter into a back incision of a patient with previous spinal fusion.
Suryadevara R, Lieber BA, Garcia E, Sood S, Haridas A, Ham S
Childs Nerv Syst 2018 Apr;34(4):787-789. Epub 2018 Jan 2 doi: 10.1007/s00381-017-3689-2. PMID: 29294141
Sacral spinous processes: a morphologic classification and biomechanical characterization of strength.
Wang T, Fielding LC, Parikh A, Kothari M, Alamin T
Spine J 2015 Dec 1;15(12):2544-51. Epub 2015 Sep 4 doi: 10.1016/j.spinee.2015.08.058. PMID: 26343242
Spina bifida occulta: not to be overlooked in children with nocturnal enuresis.
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087
High prevalence of incontinence among young adults with spina bifida: description, prediction and problem perception.
Verhoef M, Lurvink M, Barf HA, Post MW, van Asbeck FW, Gooskens RH, Prevo AJ
Spinal Cord 2005 Jun;43(6):331-40. doi: 10.1038/sj.sc.3101705. PMID: 15685262
Adult diastematomyelia.
Linn RM, Ford LT
Spine (Phila Pa 1976) 1994 Apr 1;19(7):852-4. doi: 10.1097/00007632-199404000-00024. PMID: 8202809

Prognosis

Ultrasonographic images of spina bifida before obstetric anesthesia: a case series.
Doi M, Sakurai Y, Sakamaki D, Tanaka S, Katori N, Uezono S
BMC Anesthesiol 2023 Apr 24;23(1):134. doi: 10.1186/s12871-023-02101-4. PMID: 37095440Free PMC Article
The adverse influence of spina bifida occulta on the medical treatment outcome of primary monosymptomatic nocturnal enuresis.
Cakiroglu B, Tas T, Eyyupoglu SE, Hazar AI, Can Balcı MB, Nas Y, Yilmazer F, Aksoy SH
Arch Ital Urol Androl 2014 Dec 30;86(4):270-3. doi: 10.4081/aiua.2014.4.270. PMID: 25641449
Spina bifida occulta: not to be overlooked in children with nocturnal enuresis.
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087
Spina bifida occulta: is it a predictor of underlying spinal cord abnormality in patients with lower urinary tract dysfunction?
Nejat F, Radmanesh F, Ansari S, Tajik P, Kajbafzadeh A, El Khashab M
J Neurosurg Pediatr 2008 Feb;1(2):114-7. doi: 10.3171/PED/2008/1/2/114. PMID: 18352778
High prevalence of incontinence among young adults with spina bifida: description, prediction and problem perception.
Verhoef M, Lurvink M, Barf HA, Post MW, van Asbeck FW, Gooskens RH, Prevo AJ
Spinal Cord 2005 Jun;43(6):331-40. doi: 10.1038/sj.sc.3101705. PMID: 15685262

Clinical prediction guides

The effect of transitional vertebrae and spina bifida occulta on disc herniation, disc degeneration, and end-plate changes in pediatric patients with low back pain.
Illeez OG, Ulger FEB, Aktas I
Acta Orthop Belg 2022 Jun;88(2):275-283. doi: 10.52628/88.2.8528. PMID: 36001833
Repair of symptomatic bilateral L5 spondylolysis with autogenous iliac crest graft and temporary intersegmental pedicle screw fixation in youth.
Zhang ZC, Zhang Y, Zhang LZ, Guan K, Zhao GM, Ren DJ, Li F, Sun TS
J Orthop Surg Res 2021 Jul 2;16(1):422. doi: 10.1186/s13018-021-02534-y. PMID: 34215290Free PMC Article
The adverse influence of spina bifida occulta on the medical treatment outcome of primary monosymptomatic nocturnal enuresis.
Cakiroglu B, Tas T, Eyyupoglu SE, Hazar AI, Can Balcı MB, Nas Y, Yilmazer F, Aksoy SH
Arch Ital Urol Androl 2014 Dec 30;86(4):270-3. doi: 10.4081/aiua.2014.4.270. PMID: 25641449
Spina bifida occulta: not to be overlooked in children with nocturnal enuresis.
Shin SH, Im YJ, Lee MJ, Lee YS, Choi EK, Han SW
Int J Urol 2013 Aug;20(8):831-5. Epub 2013 Jan 8 doi: 10.1111/iju.12054. PMID: 23294087
Incidental spina bifida occulta in functional enuresis observed during laser reflexo therapy.
Kalra V, Palaksha HK
J Child Neurol 1999 Aug;14(8):541-3. doi: 10.1177/088307389901400812. PMID: 10456767

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