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Weakness of muscles of respiration

MedGen UID:
870886
•Concept ID:
C4025347
•
Finding
HPO: HP:0004347

Definition

Reduced function of the muscles required to generate subatmospheric pressure in the thoracic cavity during breathing [from HPO]

Professional guidelines

PubMed

Mechanical ventilation and COPD: from pathophysiology to ventilatory management.
Scaramuzzo G, Ottaviani I, Volta CA, Spadaro S
Minerva Med 2022 Jun;113(3):460-470. doi: 10.23736/S0026-4806.22.07974-5. PMID: 35856181
Respiratory Sarcopenia and Sarcopenic Respiratory Disability: Concepts, Diagnosis, and Treatment.
Nagano A, Wakabayashi H, Maeda K, Kokura Y, Miyazaki S, Mori T, Fujiwara D
J Nutr Health Aging 2021;25(4):507-515. doi: 10.1007/s12603-021-1587-5. PMID: 33786569Free PMC Article
Care management in amyotrophic lateral sclerosis.
Soriani MH, Desnuelle C
Rev Neurol (Paris) 2017 May;173(5):288-299. Epub 2017 Apr 29 doi: 10.1016/j.neurol.2017.03.031. PMID: 28461024

Recent clinical studies

Etiology

Myasthenic crisis.
Claytor B, Cho SM, Li Y
Muscle Nerve 2023 Jul;68(1):8-19. Epub 2023 Apr 28 doi: 10.1002/mus.27832. PMID: 37114503
ICU-acquired weakness.
Vanhorebeek I, Latronico N, Van den Berghe G
Intensive Care Med 2020 Apr;46(4):637-653. Epub 2020 Feb 19 doi: 10.1007/s00134-020-05944-4. PMID: 32076765Free PMC Article
Nemaline myopathies: a current view.
Sewry CA, Laitila JM, Wallgren-Pettersson C
J Muscle Res Cell Motil 2019 Jun;40(2):111-126. Epub 2019 Jun 21 doi: 10.1007/s10974-019-09519-9. PMID: 31228046Free PMC Article
Critical illness-associated diaphragm weakness.
Dres M, Goligher EC, Heunks LMA, Brochard LJ
Intensive Care Med 2017 Oct;43(10):1441-1452. Epub 2017 Sep 15 doi: 10.1007/s00134-017-4928-4. PMID: 28917004
Clinical review: intensive care unit acquired weakness.
Hermans G, Van den Berghe G
Crit Care 2015 Aug 5;19(1):274. doi: 10.1186/s13054-015-0993-7. PMID: 26242743Free PMC Article

Diagnosis

Myasthenic crisis.
Claytor B, Cho SM, Li Y
Muscle Nerve 2023 Jul;68(1):8-19. Epub 2023 Apr 28 doi: 10.1002/mus.27832. PMID: 37114503
Assessing Diaphragmatic Function.
Schepens T, Fard S, Goligher EC
Respir Care 2020 Jun;65(6):807-819. doi: 10.4187/respcare.07410. PMID: 32457172
ICU-acquired weakness.
Vanhorebeek I, Latronico N, Van den Berghe G
Intensive Care Med 2020 Apr;46(4):637-653. Epub 2020 Feb 19 doi: 10.1007/s00134-020-05944-4. PMID: 32076765Free PMC Article
Diaphragm Dysfunction in Critical Illness.
Supinski GS, Morris PE, Dhar S, Callahan LA
Chest 2018 Apr;153(4):1040-1051. Epub 2017 Sep 5 doi: 10.1016/j.chest.2017.08.1157. PMID: 28887062Free PMC Article
Clinical review: intensive care unit acquired weakness.
Hermans G, Van den Berghe G
Crit Care 2015 Aug 5;19(1):274. doi: 10.1186/s13054-015-0993-7. PMID: 26242743Free PMC Article

Therapy

Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort.
Goligher EC, Jonkman AH, Dianti J, Vaporidi K, Beitler JR, Patel BK, Yoshida T, Jaber S, Dres M, Mauri T, Bellani G, Demoule A, Brochard L, Heunks L
Intensive Care Med 2020 Dec;46(12):2314-2326. Epub 2020 Nov 2 doi: 10.1007/s00134-020-06288-9. PMID: 33140181Free PMC Article
Assessing Diaphragmatic Function.
Schepens T, Fard S, Goligher EC
Respir Care 2020 Jun;65(6):807-819. doi: 10.4187/respcare.07410. PMID: 32457172
Monitoring diaphragm function in the ICU.
Dres M, Demoule A
Curr Opin Crit Care 2020 Feb;26(1):18-25. doi: 10.1097/MCC.0000000000000682. PMID: 31876624
Diaphragm Dysfunction in Critical Illness.
Supinski GS, Morris PE, Dhar S, Callahan LA
Chest 2018 Apr;153(4):1040-1051. Epub 2017 Sep 5 doi: 10.1016/j.chest.2017.08.1157. PMID: 28887062Free PMC Article
Critical illness-associated diaphragm weakness.
Dres M, Goligher EC, Heunks LMA, Brochard LJ
Intensive Care Med 2017 Oct;43(10):1441-1452. Epub 2017 Sep 15 doi: 10.1007/s00134-017-4928-4. PMID: 28917004

Prognosis

Myasthenic crisis.
Claytor B, Cho SM, Li Y
Muscle Nerve 2023 Jul;68(1):8-19. Epub 2023 Apr 28 doi: 10.1002/mus.27832. PMID: 37114503
Mechanical ventilation in Guillain-Barré syndrome.
Shang P, Zhu M, Baker M, Feng J, Zhou C, Zhang HL
Expert Rev Clin Immunol 2020 Nov;16(11):1053-1064. Epub 2020 Nov 25 doi: 10.1080/1744666X.2021.1840355. PMID: 33112177
Assessing Diaphragmatic Function.
Schepens T, Fard S, Goligher EC
Respir Care 2020 Jun;65(6):807-819. doi: 10.4187/respcare.07410. PMID: 32457172
Nemaline myopathies: a current view.
Sewry CA, Laitila JM, Wallgren-Pettersson C
J Muscle Res Cell Motil 2019 Jun;40(2):111-126. Epub 2019 Jun 21 doi: 10.1007/s10974-019-09519-9. PMID: 31228046Free PMC Article
Clinical review: intensive care unit acquired weakness.
Hermans G, Van den Berghe G
Crit Care 2015 Aug 5;19(1):274. doi: 10.1186/s13054-015-0993-7. PMID: 26242743Free PMC Article

Clinical prediction guides

Mechanical ventilation in Guillain-Barré syndrome.
Shang P, Zhu M, Baker M, Feng J, Zhou C, Zhang HL
Expert Rev Clin Immunol 2020 Nov;16(11):1053-1064. Epub 2020 Nov 25 doi: 10.1080/1744666X.2021.1840355. PMID: 33112177
Assessing Diaphragmatic Function.
Schepens T, Fard S, Goligher EC
Respir Care 2020 Jun;65(6):807-819. doi: 10.4187/respcare.07410. PMID: 32457172
The effect of early mobilization in critically ill patients: A meta-analysis.
Zang K, Chen B, Wang M, Chen D, Hui L, Guo S, Ji T, Shang F
Nurs Crit Care 2020 Nov;25(6):360-367. Epub 2019 Jun 20 doi: 10.1111/nicc.12455. PMID: 31219229
Intensive care unit-acquired weakness: unanswered questions and targets for future research.
Piva S, Fagoni N, Latronico N
F1000Res 2019;8 Epub 2019 Apr 17 doi: 10.12688/f1000research.17376.1. PMID: 31069055Free PMC Article
Clinical review: intensive care unit acquired weakness.
Hermans G, Van den Berghe G
Crit Care 2015 Aug 5;19(1):274. doi: 10.1186/s13054-015-0993-7. PMID: 26242743Free PMC Article

Recent systematic reviews

Systematic early versus late mobilization or standard early mobilization in mechanically ventilated adult ICU patients: systematic review and meta-analysis.
Menges D, Seiler B, Tomonaga Y, Schwenkglenks M, Puhan MA, Yebyo HG
Crit Care 2021 Jan 6;25(1):16. doi: 10.1186/s13054-020-03446-9. PMID: 33407707Free PMC Article
The effect of early mobilization in critically ill patients: A meta-analysis.
Zang K, Chen B, Wang M, Chen D, Hui L, Guo S, Ji T, Shang F
Nurs Crit Care 2020 Nov;25(6):360-367. Epub 2019 Jun 20 doi: 10.1111/nicc.12455. PMID: 31219229
Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis.
Zhang L, Hu W, Cai Z, Liu J, Wu J, Deng Y, Yu K, Chen X, Zhu L, Ma J, Qin Y
PLoS One 2019;14(10):e0223185. Epub 2019 Oct 3 doi: 10.1371/journal.pone.0223185. PMID: 31581205Free PMC Article
Early intervention (mobilization or active exercise) for critically ill adults in the intensive care unit.
Doiron KA, Hoffmann TC, Beller EM
Cochrane Database Syst Rev 2018 Mar 27;3(3):CD010754. doi: 10.1002/14651858.CD010754.pub2. PMID: 29582429Free PMC Article
Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease.
Jones S, Man WD, Gao W, Higginson IJ, Wilcock A, Maddocks M
Cochrane Database Syst Rev 2016 Oct 17;10(10):CD009419. doi: 10.1002/14651858.CD009419.pub3. PMID: 27748503Free PMC Article

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