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Abnormality of the fontanelles or cranial sutures

MedGen UID:
871380
•Concept ID:
C4025876
•
Anatomical Abnormality
HPO: HP:0000235

Definition

Any abnormality of the fontanelles (the regions covered by a thick membrane that normally ossify in the first two years of life) or the cranial sutures (the fibrous joints in which the articulating bones or cartilages of the skull are connected by sutural ligaments). [from HPO]

Professional guidelines

PubMed

The clinical manifestations, molecular mechanisms and treatment of craniosynostosis.
Stanton E, Urata M, Chen JF, Chai Y
Dis Model Mech 2022 Apr 1;15(4) Epub 2022 Apr 22 doi: 10.1242/dmm.049390. PMID: 35451466Free PMC Article
Cleidocranial Dysplasia: A Review of Clinical, Radiological, Genetic Implications and a Guidelines Proposal.
Farrow E, Nicot R, Wiss A, Laborde A, Ferri J
J Craniofac Surg 2018 Mar;29(2):382-389. doi: 10.1097/SCS.0000000000004200. PMID: 29189406
Craniosynostosis - Recognition, clinical characteristics, and treatment.
Kajdic N, Spazzapan P, Velnar T
Bosn J Basic Med Sci 2018 May 20;18(2):110-116. doi: 10.17305/bjbms.2017.2083. PMID: 28623672Free PMC Article

Recent clinical studies

Etiology

Craniosynostosis: Clinical Presentation, Genetics, and Prenatal Diagnosis.
Brah TK, Thind R, Abel DE
Obstet Gynecol Surv 2020 Oct;75(10):636-644. doi: 10.1097/OGX.0000000000000830. PMID: 33111964
Craniosynostosis and hypophosphatasia.
Di Rocco F, Baujat G, Cormier-Daire V, Rothenbuhler A, Linglart A
Arch Pediatr 2017 May;24(5S2):5S89-5S92. doi: 10.1016/S0929-693X(18)30022-8. PMID: 29405940
Tooth-borne vs bone-borne rapid maxillary expanders in late adolescence.
Lin L, Ahn HW, Kim SJ, Moon SC, Kim SH, Nelson G
Angle Orthod 2015 Mar;85(2):253-62. Epub 2014 Dec 9 doi: 10.2319/030514-156.1. PMID: 25490552Free PMC Article
Midpalatal suture maturation: classification method for individual assessment before rapid maxillary expansion.
Angelieri F, Cevidanes LH, Franchi L, Gonçalves JR, Benavides E, McNamara JA Jr
Am J Orthod Dentofacial Orthop 2013 Nov;144(5):759-69. doi: 10.1016/j.ajodo.2013.04.022. PMID: 24182592Free PMC Article
Posterior plagiocephaly.
Kalra R, Walker ML
Childs Nerv Syst 2012 Sep;28(9):1389-93. Epub 2012 Aug 8 doi: 10.1007/s00381-012-1784-y. PMID: 22872253

Diagnosis

Craniosynostosis: Clinical Presentation, Genetics, and Prenatal Diagnosis.
Brah TK, Thind R, Abel DE
Obstet Gynecol Surv 2020 Oct;75(10):636-644. doi: 10.1097/OGX.0000000000000830. PMID: 33111964
A review of the management of single-suture craniosynostosis, past, present, and future.
Proctor MR, Meara JG
J Neurosurg Pediatr 2019 Dec 1;24(6):622-631. doi: 10.3171/2019.7.PEDS18585. PMID: 31786542
Craniosynostosis - Recognition, clinical characteristics, and treatment.
Kajdic N, Spazzapan P, Velnar T
Bosn J Basic Med Sci 2018 May 20;18(2):110-116. doi: 10.17305/bjbms.2017.2083. PMID: 28623672Free PMC Article
Posterior plagiocephaly.
Kalra R, Walker ML
Childs Nerv Syst 2012 Sep;28(9):1389-93. Epub 2012 Aug 8 doi: 10.1007/s00381-012-1784-y. PMID: 22872253
Craniosynostosis.
Johnson D, Wilkie AO
Eur J Hum Genet 2011 Apr;19(4):369-76. Epub 2011 Jan 19 doi: 10.1038/ejhg.2010.235. PMID: 21248745Free PMC Article

Therapy

Diagnosis and Surgical Management of Neonatal Hydrocephalus.
Pindrik J, Schulz L, Drapeau A
Semin Pediatr Neurol 2022 Jul;42:100969. Epub 2022 Apr 8 doi: 10.1016/j.spen.2022.100969. PMID: 35868728
Skeletal and alveolar changes in conventional rapid palatal expansion (RPE) and miniscrew-assisted RPE (MARPE): a prospective randomized clinical trial using low-dose CBCT.
Chun JH, de Castro ACR, Oh S, Kim KH, Choi SH, Nojima LI, Nojima MDCG, Lee KJ
BMC Oral Health 2022 Apr 8;22(1):114. doi: 10.1186/s12903-022-02138-w. PMID: 35395801Free PMC Article
Syndromic Craniosynostosis.
Sawh-Martinez R, Steinbacher DM
Clin Plast Surg 2019 Apr;46(2):141-155. doi: 10.1016/j.cps.2018.11.009. PMID: 30851747
Nonsyndromic Craniosynostosis.
Dempsey RF, Monson LA, Maricevich RS, Truong TA, Olarunnipa S, Lam SK, Dauser RC, Hollier LH Jr, Buchanan EP
Clin Plast Surg 2019 Apr;46(2):123-139. Epub 2019 Jan 30 doi: 10.1016/j.cps.2018.11.001. PMID: 30851746
Congenital hypothyroidism.
Rastogi MV, LaFranchi SH
Orphanet J Rare Dis 2010 Jun 10;5:17. doi: 10.1186/1750-1172-5-17. PMID: 20537182Free PMC Article

Prognosis

Subarachnomegaly-venous congestion of infancy.
Sainz LV, Schuhmann MU
Childs Nerv Syst 2021 Nov;37(11):3455-3463. Epub 2021 Oct 23 doi: 10.1007/s00381-021-05328-z. PMID: 34687332Free PMC Article
Nonsyndromic Craniosynostosis.
Dempsey RF, Monson LA, Maricevich RS, Truong TA, Olarunnipa S, Lam SK, Dauser RC, Hollier LH Jr, Buchanan EP
Clin Plast Surg 2019 Apr;46(2):123-139. Epub 2019 Jan 30 doi: 10.1016/j.cps.2018.11.001. PMID: 30851746
Tooth-borne vs bone-borne rapid maxillary expanders in late adolescence.
Lin L, Ahn HW, Kim SJ, Moon SC, Kim SH, Nelson G
Angle Orthod 2015 Mar;85(2):253-62. Epub 2014 Dec 9 doi: 10.2319/030514-156.1. PMID: 25490552Free PMC Article
The effects of micro-implant assisted rapid palatal expansion (MARPE) on the nasomaxillary complex--a finite element method (FEM) analysis.
MacGinnis M, Chu H, Youssef G, Wu KW, Machado AW, Moon W
Prog Orthod 2014 Aug 29;15(1):52. doi: 10.1186/s40510-014-0052-y. PMID: 25242527Free PMC Article
Congenital hypothyroidism.
Rastogi MV, LaFranchi SH
Orphanet J Rare Dis 2010 Jun 10;5:17. doi: 10.1186/1750-1172-5-17. PMID: 20537182Free PMC Article

Clinical prediction guides

Ciliary Signalling and Mechanotransduction in the Pathophysiology of Craniosynostosis.
Tiberio F, Parolini O, Lattanzi W
Genes (Basel) 2021 Jul 14;12(7) doi: 10.3390/genes12071073. PMID: 34356089Free PMC Article
Evaluation of factors related to the success of miniscrew-assisted rapid palatal expansion.
Oliveira CB, Ayub P, Angelieri F, Murata WH, Suzuki SS, Ravelli DB, Santos-Pinto A
Angle Orthod 2021 Mar 1;91(2):187-194. doi: 10.2319/051420-436.1. PMID: 33351888Free PMC Article
Nonsyndromic Craniosynostosis.
Dempsey RF, Monson LA, Maricevich RS, Truong TA, Olarunnipa S, Lam SK, Dauser RC, Hollier LH Jr, Buchanan EP
Clin Plast Surg 2019 Apr;46(2):123-139. Epub 2019 Jan 30 doi: 10.1016/j.cps.2018.11.001. PMID: 30851746
The effects of micro-implant assisted rapid palatal expansion (MARPE) on the nasomaxillary complex--a finite element method (FEM) analysis.
MacGinnis M, Chu H, Youssef G, Wu KW, Machado AW, Moon W
Prog Orthod 2014 Aug 29;15(1):52. doi: 10.1186/s40510-014-0052-y. PMID: 25242527Free PMC Article
Midpalatal suture maturation: classification method for individual assessment before rapid maxillary expansion.
Angelieri F, Cevidanes LH, Franchi L, Gonçalves JR, Benavides E, McNamara JA Jr
Am J Orthod Dentofacial Orthop 2013 Nov;144(5):759-69. doi: 10.1016/j.ajodo.2013.04.022. PMID: 24182592Free PMC Article

Recent systematic reviews

The minimal access cranial suspension (MACS) lift: A systematic review of literature 18 years after its introduction.
Hijkoop LF, Stevens HPJD, van der Lei B
J Plast Reconstr Aesthet Surg 2022 Mar;75(3):1187-1196. Epub 2021 Nov 15 doi: 10.1016/j.bjps.2021.11.051. PMID: 34922854
Postnatal diagnosis of single-suture craniosynostosis with cranial ultrasound: a systematic review.
Whittall I, Lambert WA, Moote DJ, Bookland MJ, Martin JE, Hughes CD, Hersh DS
Childs Nerv Syst 2021 Dec;37(12):3705-3714. Epub 2021 Oct 5 doi: 10.1007/s00381-021-05301-w. PMID: 34611761
The State of Technology in Craniosynostosis.
Safran T, Viezel-Mathieu A, Beland B, Azzi AJ, Galli R, Gilardino M
J Craniofac Surg 2018 Jun;29(4):904-907. doi: 10.1097/SCS.0000000000004399. PMID: 29498975
Determining the fate of cranial sutures after surgical correction of non-syndromic craniosynostosis.
Kim SY, Shin HJ, Lim SY
J Craniomaxillofac Surg 2017 Nov;45(11):1801-1808. Epub 2017 Aug 19 doi: 10.1016/j.jcms.2017.08.009. PMID: 28939204
Effects of rapid maxillary expansion on the midpalatal suture: a systematic review.
Liu S, Xu T, Zou W
Eur J Orthod 2015 Dec;37(6):651-5. Epub 2015 Feb 19 doi: 10.1093/ejo/cju100. PMID: 25700989

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