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Intestinal type adenocarcinoma

MedGen UID:
87206
•Concept ID:
C0334279
•
Neoplastic Process
Synonyms: Adenocarcinoma - intestinal type; Adenocarcinoma, intestinal type; Carcinoma - intestinal type; Carcinoma, intestinal type; intestinal type adenocarcinoma; Intestinal Type Carcinoma; intestinal type carcinoma; Intestinal-Type Adenocarcinoma; intestinal-type adenocarcinoma
SNOMED CT: Carcinoma - intestinal type (25190001); Adenocarcinoma - intestinal type (25190001); Adenocarcinoma, intestinal type (25190001); Carcinoma, intestinal type (25190001)
 
Monarch Initiative: MONDO:0006254

Definition

An adenocarcinoma arising from epithelium which has undergone intestinal metaplasia. Representative examples include gastric, gallbladder, and ampulla of Vater intestinal type adenocarcinomas. [from NCI]

Professional guidelines

PubMed

Molecular Biomarkers in Sinonasal Cancers: New Frontiers in Diagnosis and Treatment.
Turri-Zanoni M, Gravante G, Castelnuovo P
Curr Oncol Rep 2022 Jan;24(1):55-67. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01154-3. PMID: 35059992Free PMC Article
Intestinal-Type Adenocarcinoma: Classification, Immunophenotype, Molecular Features and Differential Diagnosis.
Leivo I
Head Neck Pathol 2017 Sep;11(3):295-300. Epub 2017 Mar 20 doi: 10.1007/s12105-017-0800-7. PMID: 28321774Free PMC Article
Intestinal-type sinonasal adenocarcinomas: The road to molecular diagnosis and personalized treatment.
Hoeben A, van de Winkel L, Hoebers F, Kross K, Driessen C, Slootweg P, Tjan-Heijnen VC, van Herpen C
Head Neck 2016 Oct;38(10):1564-70. Epub 2016 May 25 doi: 10.1002/hed.24416. PMID: 27224655

Recent clinical studies

Etiology

Signaling Pathways mTOR and ERK as Therapeutic Targets in Sinonasal Intestinal-Type Adenocarcinoma.
Codina-Martínez H, Lorenzo-Guerra SL, Cabal VN, García-Marín R, Suárez-Fernández L, Vivanco B, Sánchez-Fernández P, López F, Llorente JL, Hermsen MA
Int J Mol Sci 2023 Oct 12;24(20) doi: 10.3390/ijms242015110. PMID: 37894790Free PMC Article
Sinonasal intestinal- and non-intestinal-type adenocarcinoma in China: a retrospective study of 14 cases.
Li G, Shi Y, Liu Q, Zhang H, Xue K, Song X, Gu Y, Sun X, Dai Q, Yu H
Acta Otolaryngol 2023 Feb;143(2):185-190. Epub 2023 Feb 13 doi: 10.1080/00016489.2023.2175032. PMID: 36780311
Sinonasal low-grade non-intestinal-type adenocarcinoma: A retrospective analysis and literature review.
Yue C, Piao Y, Bai Y, Liu H, Zhang L
Ann Diagn Pathol 2021 Jun;52:151709. Epub 2021 Jan 29 doi: 10.1016/j.anndiagpath.2021.151709. PMID: 33550111
Sinonasal Non-Intestinal-Type Adenocarcinoma: A Retrospective Review of 22 Patients.
Bignami M, Lepera D, Volpi L, Lambertoni A, Arosio A, Pistochini A, Nicolai P, Castelnuovo P
World Neurosurg 2018 Dec;120:e962-e969. Epub 2018 Sep 6 doi: 10.1016/j.wneu.2018.08.201. PMID: 30196179
Intestinal-type adenocarcinoma of the sinonasal tract: an update.
Rampinelli V, Ferrari M, Nicolai P
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):115-121. doi: 10.1097/MOO.0000000000000445. PMID: 29389737

Diagnosis

Sinonasal intestinal- and non-intestinal-type adenocarcinoma in China: a retrospective study of 14 cases.
Li G, Shi Y, Liu Q, Zhang H, Xue K, Song X, Gu Y, Sun X, Dai Q, Yu H
Acta Otolaryngol 2023 Feb;143(2):185-190. Epub 2023 Feb 13 doi: 10.1080/00016489.2023.2175032. PMID: 36780311
Emerging concepts in sinonasal tumor research.
Lopez DC, Wadley AE, London NR Jr
Curr Opin Otolaryngol Head Neck Surg 2022 Feb 1;30(1):33-39. doi: 10.1097/MOO.0000000000000776. PMID: 34958321Free PMC Article
Intestinal-Type Adenocarcinoma: Classification, Immunophenotype, Molecular Features and Differential Diagnosis.
Leivo I
Head Neck Pathol 2017 Sep;11(3):295-300. Epub 2017 Mar 20 doi: 10.1007/s12105-017-0800-7. PMID: 28321774Free PMC Article
Intestinal-type sinonasal adenocarcinomas: The road to molecular diagnosis and personalized treatment.
Hoeben A, van de Winkel L, Hoebers F, Kross K, Driessen C, Slootweg P, Tjan-Heijnen VC, van Herpen C
Head Neck 2016 Oct;38(10):1564-70. Epub 2016 May 25 doi: 10.1002/hed.24416. PMID: 27224655
Pulmonary intestinal-type adenocarcinoma.
Maeda R, Isowa N, Onuma H, Miura H
Interact Cardiovasc Thorac Surg 2008 Apr;7(2):349-51. Epub 2008 Jan 9 doi: 10.1510/icvts.2007.168716. PMID: 18184677

Therapy

Signaling Pathways mTOR and ERK as Therapeutic Targets in Sinonasal Intestinal-Type Adenocarcinoma.
Codina-Martínez H, Lorenzo-Guerra SL, Cabal VN, García-Marín R, Suárez-Fernández L, Vivanco B, Sánchez-Fernández P, López F, Llorente JL, Hermsen MA
Int J Mol Sci 2023 Oct 12;24(20) doi: 10.3390/ijms242015110. PMID: 37894790Free PMC Article
The SINTART 1 study. A phase II non-randomised controlled trial of induction chemotherapy, surgery, photon-, proton- and carbon ion-based radiotherapy integration in patients with locally advanced resectable sinonasal tumours.
Resteghini C, Castelnuovo P, Nicolai P, Orlandi E, Bossi P, Vischioni B, Schreiber A, Gambazza S, Iacovelli NA, Battaglia P, Guzzo M, Turri-Zanoni M, Mattavelli D, Facchinetti N, Calareso G, Ravanelli M, Facco C, Tartaro T, Licitra L
Eur J Cancer 2023 Jul;187:185-194. Epub 2023 Apr 5 doi: 10.1016/j.ejca.2023.03.033. PMID: 37164774
5-fluorouracil with oxaliplatin and/or irinotecan for advanced sinonasal intestinal-type adenocarcinoma (ITAC).
Sarradin V, Betrian S, Chaltiel L, Brac De La Perriere C, Delord JP
Bull Cancer 2023 Feb;110(2):168-173. Epub 2022 Nov 10 doi: 10.1016/j.bulcan.2022.10.004. PMID: 36372589
The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
Skalova A, Sar A, Laco J, Metelkova A, Miesbauerova M, Steiner P, Švajdler M, Michal M
Appl Immunohistochem Mol Morphol 2018 Feb;26(2):140-146. doi: 10.1097/PAI.0000000000000388. PMID: 27258560
Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model.
Fiaux-Camous D, Chevret S, Oker N, Turri-Zanoni M, Lombardi D, Choussy O, Duprez F, Jorissen M, de Gabory L, Malard O, Herman P, Nicolai P, Castelnuovo P, Verillaud B
Head Neck 2017 Apr;39(4):668-678. Epub 2017 Jan 9 doi: 10.1002/hed.24663. PMID: 28067974

Prognosis

Signaling Pathways mTOR and ERK as Therapeutic Targets in Sinonasal Intestinal-Type Adenocarcinoma.
Codina-Martínez H, Lorenzo-Guerra SL, Cabal VN, García-Marín R, Suárez-Fernández L, Vivanco B, Sánchez-Fernández P, López F, Llorente JL, Hermsen MA
Int J Mol Sci 2023 Oct 12;24(20) doi: 10.3390/ijms242015110. PMID: 37894790Free PMC Article
HER2 status in sinonasal intestinal-type adenocarcinoma.
Maffeis V, Cappellesso R, Zanon A, Cazzador D, Emanuelli E, Martini A, Fassina A
Pathol Res Pract 2019 Jun;215(6):152432. Epub 2019 Apr 28 doi: 10.1016/j.prp.2019.04.024. PMID: 31047725
Sinonasal Non-Intestinal-Type Adenocarcinoma: A Retrospective Review of 22 Patients.
Bignami M, Lepera D, Volpi L, Lambertoni A, Arosio A, Pistochini A, Nicolai P, Castelnuovo P
World Neurosurg 2018 Dec;120:e962-e969. Epub 2018 Sep 6 doi: 10.1016/j.wneu.2018.08.201. PMID: 30196179
Intestinal-type adenocarcinoma of the sinonasal tract: an update.
Rampinelli V, Ferrari M, Nicolai P
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):115-121. doi: 10.1097/MOO.0000000000000445. PMID: 29389737
Intestinal-type sinonasal adenocarcinomas: The road to molecular diagnosis and personalized treatment.
Hoeben A, van de Winkel L, Hoebers F, Kross K, Driessen C, Slootweg P, Tjan-Heijnen VC, van Herpen C
Head Neck 2016 Oct;38(10):1564-70. Epub 2016 May 25 doi: 10.1002/hed.24416. PMID: 27224655

Clinical prediction guides

Molecular Biomarkers in Sinonasal Cancers: New Frontiers in Diagnosis and Treatment.
Turri-Zanoni M, Gravante G, Castelnuovo P
Curr Oncol Rep 2022 Jan;24(1):55-67. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01154-3. PMID: 35059992Free PMC Article
HER2 status in sinonasal intestinal-type adenocarcinoma.
Maffeis V, Cappellesso R, Zanon A, Cazzador D, Emanuelli E, Martini A, Fassina A
Pathol Res Pract 2019 Jun;215(6):152432. Epub 2019 Apr 28 doi: 10.1016/j.prp.2019.04.024. PMID: 31047725
RHOA mutations and CLDN18-ARHGAP fusions in intestinal-type adenocarcinoma with anastomosing glands of the stomach.
Hashimoto T, Ogawa R, Tang TY, Yoshida H, Taniguchi H, Katai H, Oda I, Sekine S
Mod Pathol 2019 Apr;32(4):568-575. Epub 2018 Nov 13 doi: 10.1038/s41379-018-0181-9. PMID: 30425335
Intestinal-type adenocarcinoma of the vagina: clinico-pathologic features of a common tumor with a rare localization.
Broggi G, Piombino E, Magro G, Vecchio GM
Pathologica 2018 Sep;110(2):92-95. PMID: 30546144
Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model.
Fiaux-Camous D, Chevret S, Oker N, Turri-Zanoni M, Lombardi D, Choussy O, Duprez F, Jorissen M, de Gabory L, Malard O, Herman P, Nicolai P, Castelnuovo P, Verillaud B
Head Neck 2017 Apr;39(4):668-678. Epub 2017 Jan 9 doi: 10.1002/hed.24663. PMID: 28067974

Recent systematic reviews

Tumors of the Nose and Paranasal Sinuses: Promoting Factors and Molecular Mechanisms-A Systematic Review.
Lucidi D, Cantaffa C, Miglio M, Spina F, Alicandri Ciufelli M, Marchioni A, Marchioni D
Int J Mol Sci 2023 Jan 31;24(3) doi: 10.3390/ijms24032670. PMID: 36768990Free PMC Article
Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model.
Fiaux-Camous D, Chevret S, Oker N, Turri-Zanoni M, Lombardi D, Choussy O, Duprez F, Jorissen M, de Gabory L, Malard O, Herman P, Nicolai P, Castelnuovo P, Verillaud B
Head Neck 2017 Apr;39(4):668-678. Epub 2017 Jan 9 doi: 10.1002/hed.24663. PMID: 28067974

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