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Fetal macrosomia

MedGen UID:
8824
Concept ID:
C0015938
Finding
Synonyms: Fetal Macrosomia; Fetal Macrosomias; Macrosomia, Fetal; Macrosomias, Fetal
SNOMED CT: Fetal macrosomia (38206000); Fetal giant (38206000)

Definition

A fetus exceeding 4500 grams. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFetal macrosomia

Professional guidelines

PubMed

Will JS, Crellin H
Am Fam Physician 2023 Sep;108(3):249-258. PMID: 37725457
Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Salomon LJ, Alfirevic Z, Da Silva Costa F, Deter RL, Figueras F, Ghi T, Glanc P, Khalil A, Lee W, Napolitano R, Papageorghiou A, Sotiriadis A, Stirnemann J, Toi A, Yeo G
Ultrasound Obstet Gynecol 2019 Jun;53(6):715-723. doi: 10.1002/uog.20272. PMID: 31169958

Recent clinical studies

Etiology

Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Damhuis SE, Ganzevoort W, Gordijn SJ
Obstet Gynecol Clin North Am 2021 Jun;48(2):267-279. doi: 10.1016/j.ogc.2021.02.002. PMID: 33972065
Obstet Gynecol 2020 Jan;135(1):e18-e35. doi: 10.1097/AOG.0000000000003606. PMID: 31856124
Araujo Júnior E, Peixoto AB, Zamarian AC, Elito Júnior J, Tonni G
Best Pract Res Clin Obstet Gynaecol 2017 Jan;38:83-96. Epub 2016 Sep 15 doi: 10.1016/j.bpobgyn.2016.08.003. PMID: 27727018
Kc K, Shakya S, Zhang H
Ann Nutr Metab 2015;66 Suppl 2:14-20. Epub 2015 Jun 2 doi: 10.1159/000371628. PMID: 26045324

Diagnosis

Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Obstet Gynecol 2020 Jan;135(1):e18-e35. doi: 10.1097/AOG.0000000000003606. PMID: 31856124
Romero R, Kingdom J, Deter R, Lee W, Vintzileos A
Am J Obstet Gynecol 2018 Feb;218(2S):S608. doi: 10.1016/j.ajog.2018.01.010. PMID: 29422202Free PMC Article
Araujo Júnior E, Peixoto AB, Zamarian AC, Elito Júnior J, Tonni G
Best Pract Res Clin Obstet Gynaecol 2017 Jan;38:83-96. Epub 2016 Sep 15 doi: 10.1016/j.bpobgyn.2016.08.003. PMID: 27727018
Pates JA, McIntire DD, Casey BM, Leveno KJ
J Ultrasound Med 2008 Jan;27(1):39-43. doi: 10.7863/jum.2008.27.1.39. PMID: 18096729

Therapy

Ye W, Luo C, Huang J, Li C, Liu Z, Liu F
BMJ 2022 May 25;377:e067946. doi: 10.1136/bmj-2021-067946. PMID: 35613728Free PMC Article
Beta J, Khan N, Khalil A, Fiolna M, Ramadan G, Akolekar R
Ultrasound Obstet Gynecol 2019 Sep;54(3):308-318. Epub 2019 Aug 2 doi: 10.1002/uog.20279. PMID: 30938004
Yamamoto JM, Kellett JE, Balsells M, García-Patterson A, Hadar E, Solà I, Gich I, van der Beek EM, Castañeda-Gutiérrez E, Heinonen S, Hod M, Laitinen K, Olsen SF, Poston L, Rueda R, Rust P, van Lieshout L, Schelkle B, Murphy HR, Corcoy R
Diabetes Care 2018 Jul;41(7):1346-1361. doi: 10.2337/dc18-0102. PMID: 29934478
Kominiarek MA, Peaceman AM
Am J Obstet Gynecol 2017 Dec;217(6):642-651. Epub 2017 May 24 doi: 10.1016/j.ajog.2017.05.040. PMID: 28549978Free PMC Article
American College of Obstetricians and Gynecologists (College); Society for Maternal-Fetal Medicine, Caughey AB, Cahill AG, Guise JM, Rouse DJ
Am J Obstet Gynecol 2014 Mar;210(3):179-93. doi: 10.1016/j.ajog.2014.01.026. PMID: 24565430

Prognosis

Hillier TA, Pedula KL, Ogasawara KK, Vesco KK, Oshiro CES, Lubarsky SL, Van Marter J
N Engl J Med 2021 Mar 11;384(10):895-904. doi: 10.1056/NEJMoa2026028. PMID: 33704936Free PMC Article
Voormolen DN, DeVries JH, Sanson RME, Heringa MP, de Valk HW, Kok M, van Loon AJ, Hoogenberg K, Bekedam DJ, Brouwer TCB, Porath M, Erdtsieck RJ, NijBijvank B, Kip H, van der Heijden OWH, Elving LD, Hermsen BB, Potter van Loon BJ, Rijnders RJP, Jansen HJ, Langenveld J, Akerboom BMC, Kiewiet RM, Naaktgeboren CA, Mol BWJ, Franx A, Evers IM
Diabetes Obes Metab 2018 Aug;20(8):1894-1902. Epub 2018 May 8 doi: 10.1111/dom.13310. PMID: 29603547
Araujo Júnior E, Peixoto AB, Zamarian AC, Elito Júnior J, Tonni G
Best Pract Res Clin Obstet Gynaecol 2017 Jan;38:83-96. Epub 2016 Sep 15 doi: 10.1016/j.bpobgyn.2016.08.003. PMID: 27727018
Landon MB, Spong CY, Thom E, Carpenter MW, Ramin SM, Casey B, Wapner RJ, Varner MW, Rouse DJ, Thorp JM Jr, Sciscione A, Catalano P, Harper M, Saade G, Lain KY, Sorokin Y, Peaceman AM, Tolosa JE, Anderson GB; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
N Engl J Med 2009 Oct 1;361(14):1339-48. doi: 10.1056/NEJMoa0902430. PMID: 19797280Free PMC Article
Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS; Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group
N Engl J Med 2005 Jun 16;352(24):2477-86. Epub 2005 Jun 12 doi: 10.1056/NEJMoa042973. PMID: 15951574

Clinical prediction guides

Shulman Y, Shah BR, Berger H, Yoon EW, Helpaerin I, Mei-Dan E, Aviram A, Retnakaran R, Melamed N
Am J Obstet Gynecol MFM 2023 Aug;5(8):101042. Epub 2023 Jun 6 doi: 10.1016/j.ajogmf.2023.101042. PMID: 37286100
Huang R, Dong Y, Levy E, Julien P, Marc I, He H, Xu YJ, Wei SQ, Fraser WD, Luo ZC
J Clin Endocrinol Metab 2022 Jan 18;107(2):e688-e697. doi: 10.1210/clinem/dgab642. PMID: 34477199
Wong SPW, Twynstra J, Gilliland JA, Cook JL, Seabrook JA
J Pediatr Adolesc Gynecol 2020 Apr;33(2):153-159. Epub 2019 Oct 18 doi: 10.1016/j.jpag.2019.10.006. PMID: 31634579
Araujo Júnior E, Peixoto AB, Zamarian AC, Elito Júnior J, Tonni G
Best Pract Res Clin Obstet Gynaecol 2017 Jan;38:83-96. Epub 2016 Sep 15 doi: 10.1016/j.bpobgyn.2016.08.003. PMID: 27727018
Pates JA, McIntire DD, Casey BM, Leveno KJ
J Ultrasound Med 2008 Jan;27(1):39-43. doi: 10.7863/jum.2008.27.1.39. PMID: 18096729

Recent systematic reviews

Ye W, Luo C, Huang J, Li C, Liu Z, Liu F
BMJ 2022 May 25;377:e067946. doi: 10.1136/bmj-2021-067946. PMID: 35613728Free PMC Article
Ribeiro MM, Andrade A, Nunes I
J Perinat Med 2022 Jan 27;50(1):4-17. Epub 2021 Sep 6 doi: 10.1515/jpm-2021-0315. PMID: 34478617
Beta J, Khan N, Khalil A, Fiolna M, Ramadan G, Akolekar R
Ultrasound Obstet Gynecol 2019 Sep;54(3):308-318. Epub 2019 Aug 2 doi: 10.1002/uog.20279. PMID: 30938004
Yamamoto JM, Kellett JE, Balsells M, García-Patterson A, Hadar E, Solà I, Gich I, van der Beek EM, Castañeda-Gutiérrez E, Heinonen S, Hod M, Laitinen K, Olsen SF, Poston L, Rueda R, Rust P, van Lieshout L, Schelkle B, Murphy HR, Corcoy R
Diabetes Care 2018 Jul;41(7):1346-1361. doi: 10.2337/dc18-0102. PMID: 29934478
Goldstein RF, Abell SK, Ranasinha S, Misso M, Boyle JA, Black MH, Li N, Hu G, Corrado F, Rode L, Kim YJ, Haugen M, Song WO, Kim MH, Bogaerts A, Devlieger R, Chung JH, Teede HJ
JAMA 2017 Jun 6;317(21):2207-2225. doi: 10.1001/jama.2017.3635. PMID: 28586887Free PMC Article

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