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P2 Hydronephrosis

MedGen UID:
887766
•Concept ID:
C4054279
•
Finding

Definition

Postnatal Hydronephrosis with the following clinical findings: 1) APRPD is greater than or equal to 15 mm, 2) the calyces may be dilated centrally and peripherally, 3) or a dilated ureter is visible, 4) the parenchymal thickness and appearance is normal, and 5) the bladder is normal. Cases in which there is peripheral calyceal dilation but the APRPD is less than 15 mm are classified as UTD P2. (Adapted from: Hiep T. Nguyen, Carol B. Benson, Bryann Bromley, Jeffrey B. Campbell, Jeanne Chow, Beverly Coleman, Christopher Cooper, Jude Crino, Kassa Darge, C.D. Anthony Herndon, Anthony O. Odibo, Michael J.G. Somers, Deborah R. Stein; Multidisciplinary consensus on the classification of prenatal and postnatal urinary tract dilation (UTD classification system); Pediatric Urology; December 2014 Volume 10, Issue 6, Pages 982-998) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVP2 Hydronephrosis

Professional guidelines

PubMed

A long-term follow-up in conservative management of unilateral ureteropelvic junction obstruction with poor drainage and good renal function.
Arena S, Chimenz R, Antonelli E, Peri FM, Romeo P, Impellizzeri P, Romeo C
Eur J Pediatr 2018 Dec;177(12):1761-1765. Epub 2018 Sep 12 doi: 10.1007/s00431-018-3239-2. PMID: 30209594

Recent clinical studies

Etiology

Clinical characteristics of patients with prenatal hydronephrosis in early postnatal period: a single center retrospective study.
Gu SL, Yang XQ, Zhai YH, Xu WL, Guo WX, Shen T
BMC Pediatr 2023 May 12;23(1):235. doi: 10.1186/s12887-023-04063-5. PMID: 37173710Free PMC Article
Outcomes of intermediate-risk hydronephrosis in pediatric patients.
Abimbola O, Smith BD, Gurjar M, Ross SS
J Pediatr Urol 2023 Apr;19(2):196.e1-196.e6. Epub 2022 Oct 8 doi: 10.1016/j.jpurol.2022.10.007. PMID: 36473783
The different elements of the Urinary Tract Dilation (UTD) Classification System and their capacity to predict findings on mercaptoacetyltriglycine (MAG3) diuretic renography.
Agard H, Massanyi E, Albertson M, Anderson M, Alam M, Lyden E, Del Rio CV
J Pediatr Urol 2020 Oct;16(5):686.e1-686.e6. Epub 2020 Aug 6 doi: 10.1016/j.jpurol.2020.07.045. PMID: 32888887
Validation of "urinary tract dilation" classification system: Correlation between fetal hydronephrosis and postnatal urological abnormalities.
Zhang H, Zhang L, Guo N
Medicine (Baltimore) 2020 Jan;99(2):e18707. doi: 10.1097/MD.0000000000018707. PMID: 31914077Free PMC Article
The association of postnatal urinary tract dilation risk score with clinical outcomes.
Nelson CP, Lee RS, Trout AT, Servaes S, Kraft KH, Barnewolt CE, Logvinenko T, Chow JS
J Pediatr Urol 2019 Aug;15(4):341.e1-341.e6. Epub 2019 May 9 doi: 10.1016/j.jpurol.2019.05.001. PMID: 31164273

Diagnosis

Outcomes of intermediate-risk hydronephrosis in pediatric patients.
Abimbola O, Smith BD, Gurjar M, Ross SS
J Pediatr Urol 2023 Apr;19(2):196.e1-196.e6. Epub 2022 Oct 8 doi: 10.1016/j.jpurol.2022.10.007. PMID: 36473783
Associations, follow up data, and postnatal outcome of antenatally diagnosed Urinary Tract Dilatation - Five-year single tertiary center experience from South India.
Paladugu S, Vasudeva A, Poojari VG, Machado NM, Roopa PS, Hegde N, Mundkur A, Kumar V
J Pediatr Urol 2023 Feb;19(1):89.e1-89.e8. Epub 2022 Oct 28 doi: 10.1016/j.jpurol.2022.10.028. PMID: 36404195
Evaluation of Urinary Tract Dilation Classification System for Prediction of Long-Term Outcomes in Isolated Antenatal Hydronephrosis: A Cohort Study.
Melo FF, Mak RH, Simões E Silva AC, Vasconcelos MA, Dias CS, Rosa LC, Shiomatsu GY, Storch C, Oliveira MCL, Oliveira EA
J Urol 2021 Oct;206(4):1022-1030. Epub 2021 Jun 8 doi: 10.1097/JU.0000000000001899. PMID: 34100626
Validation of "urinary tract dilation" classification system: Correlation between fetal hydronephrosis and postnatal urological abnormalities.
Zhang H, Zhang L, Guo N
Medicine (Baltimore) 2020 Jan;99(2):e18707. doi: 10.1097/MD.0000000000018707. PMID: 31914077Free PMC Article
The association of postnatal urinary tract dilation risk score with clinical outcomes.
Nelson CP, Lee RS, Trout AT, Servaes S, Kraft KH, Barnewolt CE, Logvinenko T, Chow JS
J Pediatr Urol 2019 Aug;15(4):341.e1-341.e6. Epub 2019 May 9 doi: 10.1016/j.jpurol.2019.05.001. PMID: 31164273

Therapy

The association of postnatal urinary tract dilation risk score with clinical outcomes.
Nelson CP, Lee RS, Trout AT, Servaes S, Kraft KH, Barnewolt CE, Logvinenko T, Chow JS
J Pediatr Urol 2019 Aug;15(4):341.e1-341.e6. Epub 2019 May 9 doi: 10.1016/j.jpurol.2019.05.001. PMID: 31164273
Preoperative chemotherapy for prostatic stromal invasive urothelial bladder cancer: comparison of oncological outcomes of male patients with cT4a disease undergoing radical cystectomy with or without preoperative chemotherapy.
Chen J, Miranda G, Cai J, Daneshmand S, Djaladat H
Scand J Urol 2019 Apr-Jun;53(2-3):123-128. Epub 2019 May 13 doi: 10.1080/21681805.2019.1613445. PMID: 31081431
Interobserver and Intra-Observer Reliability of the Urinary Tract Dilation Classification System in Neonates: A Multicenter Study.
Nelson CP, Lee RS, Trout AT, Servaes S, Kraft KH, Barnewolt CE, Logvinenko T, Chow JS
J Urol 2019 Jun;201(6):1186-1192. doi: 10.1097/JU.0000000000000026. PMID: 30676479

Prognosis

Associations, follow up data, and postnatal outcome of antenatally diagnosed Urinary Tract Dilatation - Five-year single tertiary center experience from South India.
Paladugu S, Vasudeva A, Poojari VG, Machado NM, Roopa PS, Hegde N, Mundkur A, Kumar V
J Pediatr Urol 2023 Feb;19(1):89.e1-89.e8. Epub 2022 Oct 28 doi: 10.1016/j.jpurol.2022.10.028. PMID: 36404195
The different elements of the Urinary Tract Dilation (UTD) Classification System and their capacity to predict findings on mercaptoacetyltriglycine (MAG3) diuretic renography.
Agard H, Massanyi E, Albertson M, Anderson M, Alam M, Lyden E, Del Rio CV
J Pediatr Urol 2020 Oct;16(5):686.e1-686.e6. Epub 2020 Aug 6 doi: 10.1016/j.jpurol.2020.07.045. PMID: 32888887
Validation of "urinary tract dilation" classification system: Correlation between fetal hydronephrosis and postnatal urological abnormalities.
Zhang H, Zhang L, Guo N
Medicine (Baltimore) 2020 Jan;99(2):e18707. doi: 10.1097/MD.0000000000018707. PMID: 31914077Free PMC Article
The association of postnatal urinary tract dilation risk score with clinical outcomes.
Nelson CP, Lee RS, Trout AT, Servaes S, Kraft KH, Barnewolt CE, Logvinenko T, Chow JS
J Pediatr Urol 2019 Aug;15(4):341.e1-341.e6. Epub 2019 May 9 doi: 10.1016/j.jpurol.2019.05.001. PMID: 31164273
A long-term follow-up in conservative management of unilateral ureteropelvic junction obstruction with poor drainage and good renal function.
Arena S, Chimenz R, Antonelli E, Peri FM, Romeo P, Impellizzeri P, Romeo C
Eur J Pediatr 2018 Dec;177(12):1761-1765. Epub 2018 Sep 12 doi: 10.1007/s00431-018-3239-2. PMID: 30209594

Clinical prediction guides

Associations, follow up data, and postnatal outcome of antenatally diagnosed Urinary Tract Dilatation - Five-year single tertiary center experience from South India.
Paladugu S, Vasudeva A, Poojari VG, Machado NM, Roopa PS, Hegde N, Mundkur A, Kumar V
J Pediatr Urol 2023 Feb;19(1):89.e1-89.e8. Epub 2022 Oct 28 doi: 10.1016/j.jpurol.2022.10.028. PMID: 36404195
Evaluation of Urinary Tract Dilation Classification System for Prediction of Long-Term Outcomes in Isolated Antenatal Hydronephrosis: A Cohort Study.
Melo FF, Mak RH, Simões E Silva AC, Vasconcelos MA, Dias CS, Rosa LC, Shiomatsu GY, Storch C, Oliveira MCL, Oliveira EA
J Urol 2021 Oct;206(4):1022-1030. Epub 2021 Jun 8 doi: 10.1097/JU.0000000000001899. PMID: 34100626
The different elements of the Urinary Tract Dilation (UTD) Classification System and their capacity to predict findings on mercaptoacetyltriglycine (MAG3) diuretic renography.
Agard H, Massanyi E, Albertson M, Anderson M, Alam M, Lyden E, Del Rio CV
J Pediatr Urol 2020 Oct;16(5):686.e1-686.e6. Epub 2020 Aug 6 doi: 10.1016/j.jpurol.2020.07.045. PMID: 32888887
The association of postnatal urinary tract dilation risk score with clinical outcomes.
Nelson CP, Lee RS, Trout AT, Servaes S, Kraft KH, Barnewolt CE, Logvinenko T, Chow JS
J Pediatr Urol 2019 Aug;15(4):341.e1-341.e6. Epub 2019 May 9 doi: 10.1016/j.jpurol.2019.05.001. PMID: 31164273
Conversion and reliability of two urological grading systems in infants: the Society for Fetal Urology and the urinary tract dilatation classifications system.
Han M, Kim HG, Lee JD, Park SY, Sur YK
Pediatr Radiol 2017 Jan;47(1):65-73. Epub 2016 Oct 10 doi: 10.1007/s00247-016-3721-9. PMID: 27725992

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