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Benign neoplasm of oral cavity

MedGen UID:
91119
Concept ID:
C0347197
Neoplastic Process
Synonyms: Benign Mouth Neoplasm; benign mouth neoplasm; Benign Mouth Tumor; benign mouth tumor; benign mouth tumour; Benign Neoplasm of Mouth; benign neoplasm of mouth; Benign Neoplasm of Oral Cavity; benign neoplasm of oral cavity; Benign Neoplasm of the Mouth; benign neoplasm of the mouth; Benign Neoplasm of the Oral Cavity; benign neoplasm of the oral cavity; Benign Oral Cavity Neoplasm; benign oral cavity neoplasm; Benign Oral Cavity Tumor; benign oral cavity tumor; benign oral cavity tumour; Benign Oral Neoplasm; Benign Oral Tumor; Benign Tumor of Mouth; benign tumor of mouth; Benign Tumor of Oral Cavity; Benign tumor of oral cavity; benign tumor of oral cavity; Benign Tumor of the Mouth; benign tumor of the mouth; Benign Tumor of the Oral Cavity; benign tumor of the oral cavity; benign tumour of mouth; benign tumour of oral cavity; benign tumour of the mouth; benign tumour of the oral cavity; Oral benign tumor; oral cavity benign neoplasm; Oral Neoplasm, Benign
SNOMED CT: Benign neoplasm of oral cavity (419645003); Benign tumor of oral cavity (419645003); Oral benign tumor (419645003)
 
Monarch Initiative: MONDO:0021445

Definition

A neoplasm that arises from the oral cavity and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include hemangioma, tongue lipoma, and buccal mucosa papilloma. [from NCI]

Professional guidelines

PubMed

Kerr AR, Lodi G
Oral Dis 2021 Nov;27(8):2008-2025. Epub 2021 Oct 9 doi: 10.1111/odi.13980. PMID: 34324758
Bowers EMR, Schaitkin B
Otolaryngol Clin North Am 2021 Jun;54(3):543-551. doi: 10.1016/j.otc.2021.03.002. PMID: 34024482
Grégoire V, Evans M, Le QT, Bourhis J, Budach V, Chen A, Eisbruch A, Feng M, Giralt J, Gupta T, Hamoir M, Helito JK, Hu C, Hunter K, Johansen J, Kaanders J, Laskar SG, Lee A, Maingon P, Mäkitie A, Micciche' F, Nicolai P, O'Sullivan B, Poitevin A, Porceddu S, Składowski K, Tribius S, Waldron J, Wee J, Yao M, Yom SS, Zimmermann F, Grau C
Radiother Oncol 2018 Jan;126(1):3-24. Epub 2017 Nov 24 doi: 10.1016/j.radonc.2017.10.016. PMID: 29180076

Recent clinical studies

Etiology

Howard A, Agrawal N, Gooi Z
Hematol Oncol Clin North Am 2021 Oct;35(5):895-911. Epub 2021 Jul 14 doi: 10.1016/j.hoc.2021.05.003. PMID: 34274176
Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, Maymone AC, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):59-71. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.060. PMID: 30447325
Maymone MBC, Greer RO, Burdine LK, Dao-Cheng A, Venkatesh S, Sahitya PC, Maymone AC, Kesecker J, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):43-56. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.061. PMID: 30447312
Montero PH, Patel SG
Surg Oncol Clin N Am 2015 Jul;24(3):491-508. Epub 2015 Apr 15 doi: 10.1016/j.soc.2015.03.006. PMID: 25979396Free PMC Article
Hübbers CU, Akgül B
Virulence 2015;6(3):244-8. doi: 10.1080/21505594.2014.999570. PMID: 25654476Free PMC Article

Diagnosis

Howard A, Agrawal N, Gooi Z
Hematol Oncol Clin North Am 2021 Oct;35(5):895-911. Epub 2021 Jul 14 doi: 10.1016/j.hoc.2021.05.003. PMID: 34274176
Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, Maymone AC, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):59-71. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.060. PMID: 30447325
Maymone MBC, Greer RO, Burdine LK, Dao-Cheng A, Venkatesh S, Sahitya PC, Maymone AC, Kesecker J, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):43-56. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.061. PMID: 30447312
Khurshid Z, Zafar MS, Khan RS, Najeeb S, Slowey PD, Rehman IU
Adv Clin Chem 2018;86:23-70. Epub 2018 Jul 23 doi: 10.1016/bs.acc.2018.05.002. PMID: 30144841
Montero PH, Patel SG
Surg Oncol Clin N Am 2015 Jul;24(3):491-508. Epub 2015 Apr 15 doi: 10.1016/j.soc.2015.03.006. PMID: 25979396Free PMC Article

Therapy

Worthington HV, Bulsara VM, Glenny AM, Clarkson JE, Conway DI, Macluskey M
Cochrane Database Syst Rev 2023 Aug 31;8(8):CD006205. doi: 10.1002/14651858.CD006205.pub5. PMID: 37650478Free PMC Article
Petrelli F, Cin ED, Ghidini A, Carioli D, Falasca V, De Stefani A, Moleri G, Ardito R, Luciani A, Nardone M, Capriotti V
Eur Arch Otorhinolaryngol 2023 Sep;280(9):3921-3930. Epub 2023 May 22 doi: 10.1007/s00405-023-08027-4. PMID: 37212863
Stringer AM, Logan RM
J Oral Pathol Med 2015 Feb;44(2):81-7. Epub 2014 Feb 4 doi: 10.1111/jop.12152. PMID: 24494824
Furness S, Glenny AM, Worthington HV, Pavitt S, Oliver R, Clarkson JE, Macluskey M, Chan KK, Conway DI
Cochrane Database Syst Rev 2011 Apr 13;(4):CD006386. doi: 10.1002/14651858.CD006386.pub3. PMID: 21491393
Day TA, Davis BK, Gillespie MB, Joe JK, Kibbey M, Martin-Harris B, Neville B, Reed SG, Richardson MS, Rosenzweig S, Sharma AK, Smith MM, Stewart S, Stuart RK
Curr Treat Options Oncol 2003 Feb;4(1):27-41. doi: 10.1007/s11864-003-0029-4. PMID: 12525277

Prognosis

Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L, Gregoire V; EHNS Executive Board. Electronic address: secretariat@ehns.org; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org; ESTRO Executive Board. Electronic address: info@estro.org
Ann Oncol 2020 Nov;31(11):1462-1475. Epub 2020 Oct 23 doi: 10.1016/j.annonc.2020.07.011. PMID: 33239190
Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, Maymone AC, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):59-71. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.060. PMID: 30447325
Khurshid Z, Zafar MS, Khan RS, Najeeb S, Slowey PD, Rehman IU
Adv Clin Chem 2018;86:23-70. Epub 2018 Jul 23 doi: 10.1016/bs.acc.2018.05.002. PMID: 30144841
Montero PH, Patel SG
Surg Oncol Clin N Am 2015 Jul;24(3):491-508. Epub 2015 Apr 15 doi: 10.1016/j.soc.2015.03.006. PMID: 25979396Free PMC Article
Hübbers CU, Akgül B
Virulence 2015;6(3):244-8. doi: 10.1080/21505594.2014.999570. PMID: 25654476Free PMC Article

Clinical prediction guides

Petrelli F, Cin ED, Ghidini A, Carioli D, Falasca V, De Stefani A, Moleri G, Ardito R, Luciani A, Nardone M, Capriotti V
Eur Arch Otorhinolaryngol 2023 Sep;280(9):3921-3930. Epub 2023 May 22 doi: 10.1007/s00405-023-08027-4. PMID: 37212863
Marcus C, Subramaniam RM
PET Clin 2022 Apr;17(2):223-234. Epub 2022 Mar 4 doi: 10.1016/j.cpet.2021.12.005. PMID: 35256303
Wu DD, Ngowi EE, Zhai YK, Wang YZ, Khan NH, Kombo AF, Khattak S, Li T, Ji XY
Oxid Med Cell Longev 2022;2022:1886277. Epub 2022 Jan 25 doi: 10.1155/2022/1886277. PMID: 35116090Free PMC Article
Sideras P, Singh G
Top Magn Reson Imaging 2021 Apr 1;30(2):97-104. doi: 10.1097/RMR.0000000000000283. PMID: 33828061
Hagiwara M, Nusbaum A, Schmidt BL
Magn Reson Imaging Clin N Am 2012 Aug;20(3):473-94. Epub 2012 Jul 3 doi: 10.1016/j.mric.2012.05.003. PMID: 22877952

Recent systematic reviews

Lawler T, Warren Andersen S
Nutrients 2023 Jan 13;15(2) doi: 10.3390/nu15020422. PMID: 36678292Free PMC Article
Parmar A, Macluskey M, Mc Goldrick N, Conway DI, Glenny AM, Clarkson JE, Worthington HV, Chan KK
Cochrane Database Syst Rev 2021 Dec 20;12(12):CD006386. doi: 10.1002/14651858.CD006386.pub4. PMID: 34929047Free PMC Article
Ramos-Garcia P, Roca-Rodriguez MDM, Aguilar-Diosdado M, Gonzalez-Moles MA
Oral Dis 2021 Apr;27(3):404-421. Epub 2020 Feb 18 doi: 10.1111/odi.13289. PMID: 31994293
Wang YH, Li JQ, Shi JF, Que JY, Liu JJ, Lappin JM, Leung J, Ravindran AV, Chen WQ, Qiao YL, Shi J, Lu L, Bao YP
Mol Psychiatry 2020 Jul;25(7):1487-1499. Epub 2019 Nov 19 doi: 10.1038/s41380-019-0595-x. PMID: 31745237
Dort JC, Farwell DG, Findlay M, Huber GF, Kerr P, Shea-Budgell MA, Simon C, Uppington J, Zygun D, Ljungqvist O, Harris J
JAMA Otolaryngol Head Neck Surg 2017 Mar 1;143(3):292-303. doi: 10.1001/jamaoto.2016.2981. PMID: 27737447

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