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Ileal Diseases

MedGen UID:
9409
•Concept ID:
C0020875
•
Disease or Syndrome
Synonyms: Disease, Ileal; Diseases, Ileal; Ileal Disease

Definition

Pathological development in the ILEUM including the ILEOCECAL VALVE. [from MeSH]

Professional guidelines

PubMed

Inflammatory Bowel Disease: Clinical Diagnosis and Surgical Treatment-Overview.
M'Koma AE
Medicina (Kaunas) 2022 Apr 21;58(5) doi: 10.3390/medicina58050567. PMID: 35629984Free PMC Article
Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium.
Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, Cross RK, Sugita A, Schairer J, Kiran RP, Fleshner P, McCormick JT, D'Hoore A, Shah SA, Farraye FA, Kariv R, Liu X, Rosh J, Chang S, Scherl E, Schwartz DA, Kotze PG, Bruining DH, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, Picoraro JA, Vermeire S, Sandborn WJ, Silverberg MS, Pardi DS
Lancet Gastroenterol Hepatol 2022 Jan;7(1):69-95. Epub 2021 Nov 10 doi: 10.1016/S2468-1253(21)00214-4. PMID: 34774224
Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium.
Shen B, Kochhar GS, Kariv R, Liu X, Navaneethan U, Rubin DT, Cross RK, Sugita A, D'Hoore A, Schairer J, Farraye FA, Kiran RP, Fleshner P, Rosh J, Shah SA, Chang S, Scherl E, Pardi DS, Schwartz DA, Kotze PG, Bruining DH, Kane SV, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, McCormick JT, Picoraro JA, Silverberg MS, Bernstein CN, Sandborn WJ, Vermeire S
Lancet Gastroenterol Hepatol 2021 Oct;6(10):826-849. Epub 2021 Aug 18 doi: 10.1016/S2468-1253(21)00101-1. PMID: 34416186

Recent clinical studies

Etiology

An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease.
Wehkamp J, Stange EF
Front Immunol 2020;11:646. Epub 2020 Apr 15 doi: 10.3389/fimmu.2020.00646. PMID: 32351509Free PMC Article
Neonatal vermiform appendicopathy.
Bengtsson BO, van Houten JP
Am J Perinatol 2015 Jun;32(7):683-8. Epub 2014 Oct 6 doi: 10.1055/s-0034-1393934. PMID: 25285399
Intussusception.
Winslow BT, Westfall JM, Nicholas RA
Am Fam Physician 1996 Jul;54(1):213-7, 220. PMID: 8677837
Ileosigmoid knotting.
Gibney EJ, Mock CN
Dis Colon Rectum 1993 Sep;36(9):855-7. doi: 10.1007/BF02047383. PMID: 8375228
Pseudomelanosis duodeni.
West B
J Clin Gastroenterol 1988 Apr;10(2):127-9. PMID: 3047212

Diagnosis

Plum Pit Bezoar.
Herbst MK, Ledford M, Chang K
Ann Emerg Med 2022 Feb;79(2):e11-e12. doi: 10.1016/j.annemergmed.2021.08.020. PMID: 35065750
Strangulated umbilical hernia.
Blanco Rodicio A, Pichel Loureiro Á
Emergencias 2019 Feb;31(1):74. PMID: 30656888
Snapshot quiz.
Br J Surg 2018 Oct;105(11):1492. doi: 10.1002/bjs.10957. PMID: 30221766
Ileocecal Intussusception.
Cook MA, Shah J
J Am Osteopath Assoc 2016 Apr;116(4):268. doi: 10.7556/jaoa.2016.053. PMID: 27018962
Laparoscopic-assisted enteroscopy.
Baker S, Nisar A, Paice AG, Abdulaal Y
Ann R Coll Surg Engl 2010 Apr;92(3):W4-6. doi: 10.1308/147870810X12659688851311. PMID: 20412658Free PMC Article

Therapy

Plum Pit Bezoar.
Herbst MK, Ledford M, Chang K
Ann Emerg Med 2022 Feb;79(2):e11-e12. doi: 10.1016/j.annemergmed.2021.08.020. PMID: 35065750
Gallstone Ileus Post-cholecystectomy.
Månsson C, Norlén O
Acta Chir Belg 2015 Mar-Apr;115(2):159-61. doi: 10.1080/00015458.2015.11681087. PMID: 26021951
Effect of alcohol consumption on the gut.
Rajendram R, Preedy VR
Dig Dis 2005;23(3-4):214-21. doi: 10.1159/000090168. PMID: 16508285
Intermittent intussusception.
Mapagu C, Lam A, Martin HC, Fitzgerald DA
J Paediatr Child Health 2003 Mar;39(2):147-8. doi: 10.1046/j.1440-1754.2003.00115.x. PMID: 12603807
Short-bowel syndrome: a collective review.
Galea MH, Holliday H, Carachi R, Kapila L
J Pediatr Surg 1992 May;27(5):592-6. doi: 10.1016/0022-3468(92)90455-g. PMID: 1625129

Prognosis

Aortoenteric fistula.
Rossi UG, Cariati M
J Cardiovasc Comput Tomogr 2015 Sep-Oct;9(5):461-2. Epub 2015 Apr 2 doi: 10.1016/j.jcct.2015.03.009. PMID: 25958007
Strangulated obturator hernia.
Gupta R, Singh H, Kang M, Singh R
BMJ Case Rep 2014 Nov 20;2014 doi: 10.1136/bcr-2014-207071. PMID: 25414225Free PMC Article
Effect of alcohol consumption on the gut.
Rajendram R, Preedy VR
Dig Dis 2005;23(3-4):214-21. doi: 10.1159/000090168. PMID: 16508285
Short-bowel syndrome: a collective review.
Galea MH, Holliday H, Carachi R, Kapila L
J Pediatr Surg 1992 May;27(5):592-6. doi: 10.1016/0022-3468(92)90455-g. PMID: 1625129
Anorectal Crohn's disease.
Williams NS, Macfie J, Celestin LR
Br J Surg 1979 Oct;66(10):743-8. doi: 10.1002/bjs.1800661018. PMID: 509052

Clinical prediction guides

Clinical Course and Prognosis of Isolated Terminal Ileal Ulcers.
He X, Chen Y, Zhou X, Lu C
Arch Iran Med 2023 Aug 1;26(8):434-438. doi: 10.34172/aim.2023.66. PMID: 38301105Free PMC Article
Crohn's disease: Why the ileum?
Richard N, Savoye G, Leboutte M, Amamou A, Ghosh S, Marion-Letellier R
World J Gastroenterol 2023 Jun 7;29(21):3222-3240. doi: 10.3748/wjg.v29.i21.3222. PMID: 37377591Free PMC Article
Constrictive and Hypertrophic Strictures in Ileal Crohn's Disease.
Liu Q, Zhang X, Ko HM, Stocker D, Ellman J, Chen J, Hao Y, Bhardwaj S, Liang Y, Cho J, Colombel JF, Taouli B, Harpaz N
Clin Gastroenterol Hepatol 2022 Jun;20(6):e1292-e1304. Epub 2021 Aug 14 doi: 10.1016/j.cgh.2021.08.012. PMID: 34400338
Clinical Course of Terminal Ileal Ulcers Observed Incidentally During Colonoscopy.
Kim JH, Lee JY, Park YE, Lee JH, Park J, Kim TO, Moon W, Park SJ; Busan Ulsan Gyeongnam Intestinal Study Group Society (BIGS)
Dig Dis Sci 2021 Dec;66(12):4423-4428. Epub 2021 Mar 16 doi: 10.1007/s10620-020-06781-7. PMID: 33723699
Aortoenteric fistula.
Rossi UG, Cariati M
J Cardiovasc Comput Tomogr 2015 Sep-Oct;9(5):461-2. Epub 2015 Apr 2 doi: 10.1016/j.jcct.2015.03.009. PMID: 25958007

Recent systematic reviews

A systematic review of symptomatic hamartomas of the jejunum and ileum.
Farkas N, Conroy M, Baig M
Ann R Coll Surg Engl 2022 Jan;104(1):18-23. Epub 2021 Sep 21 doi: 10.1308/rcsann.2021.0038. PMID: 34545759Free PMC Article
Post-cholecystectomy Gallstone Ileus.
Meier J, Guzzetta AA, Huerta S
Am Surg 2020 Jun;86(6):675-684. doi: 10.1177/0003134820923296. PMID: 32683979
Outpatient management of intussusception: a systematic review and meta-analysis.
Litz CN, Amankwah EK, Polo RL, Sakmar KA, Danielson PD, Chandler NM
J Pediatr Surg 2019 Jul;54(7):1316-1323. Epub 2018 Oct 22 doi: 10.1016/j.jpedsurg.2018.09.019. PMID: 30503194
Not all diverticulites are colonic: small bowel diverticulitis - A systematic review.
De Simone B, Alberici L, Ansaloni L, Sartelli M, Coccolini F, Catena F
Minerva Chir 2019 Apr;74(2):137-145. Epub 2018 May 24 doi: 10.23736/S0026-4733.18.07745-3. PMID: 29795067
Recurrence rates after intussusception enema reduction: a meta-analysis.
Gray MP, Li SH, Hoffmann RG, Gorelick MH
Pediatrics 2014 Jul;134(1):110-9. Epub 2014 Jun 16 doi: 10.1542/peds.2013-3102. PMID: 24935997

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