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Pituitary cancer

MedGen UID:
96922
•Concept ID:
C0496842
•
Neoplastic Process
Synonyms: CA - Cancer of pituitary gland; Cancer of pituitary gland; cancer of pituitary gland; Malignant Neoplasm of Pituitary; malignant neoplasm of pituitary; Malignant Neoplasm of Pituitary Gland; malignant neoplasm of pituitary gland; Malignant Neoplasm of the Pituitary; malignant neoplasm of the pituitary; Malignant Neoplasm of the Pituitary Gland; malignant neoplasm of the pituitary gland; Malignant Pituitary Gland Neoplasm; malignant pituitary gland neoplasm; Malignant Pituitary Gland Tumor; malignant pituitary gland tumor; malignant pituitary gland tumour; Malignant Pituitary Neoplasm; malignant pituitary neoplasm; Malignant Pituitary Tumor; malignant pituitary tumor; malignant pituitary tumour; Malignant Tumor of Pituitary; malignant tumor of pituitary; Malignant tumor of pituitary gland; Malignant Tumor of Pituitary Gland; malignant tumor of pituitary gland; Malignant Tumor of the Pituitary; malignant tumor of the pituitary; Malignant Tumor of the Pituitary Gland; malignant tumor of the pituitary gland; malignant tumour of pituitary; malignant tumour of pituitary gland; malignant tumour of the pituitary; malignant tumour of the pituitary gland; pituitary cancer; pituitary gland cancer; Pituitary Neoplasms, Malignant; pituitary neoplasms, malignant; Pituitary Tumor, Malignant; pituitary tumor, malignant
SNOMED CT: Cancer of pituitary gland (363482009); CA - Cancer of pituitary gland (363482009); Pituitary cancer (363482009); Malignant tumor of pituitary gland (363482009)
 
Monarch Initiative: MONDO:0002109

Definition

A primary or metastatic malignant neoplasm affecting the pituitary gland. [from NCI]

Professional guidelines

PubMed

Diagnosis and Management of Pituitary Adenomas: A Review.
Tritos NA, Miller KK
JAMA 2023 Apr 25;329(16):1386-1398. doi: 10.1001/jama.2023.5444. PMID: 37097352
Consensus on diagnosis and management of Cushing's disease: a guideline update.
Fleseriu M, Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR, Boguszewski CL, Bronstein MD, Buchfelder M, Carmichael JD, Casanueva FF, Castinetti F, Chanson P, Findling J, Gadelha M, Geer EB, Giustina A, Grossman A, Gurnell M, Ho K, Ioachimescu AG, Kaiser UB, Karavitaki N, Katznelson L, Kelly DF, Lacroix A, McCormack A, Melmed S, Molitch M, Mortini P, Newell-Price J, Nieman L, Pereira AM, Petersenn S, Pivonello R, Raff H, Reincke M, Salvatori R, Scaroni C, Shimon I, Stratakis CA, Swearingen B, Tabarin A, Takahashi Y, Theodoropoulou M, Tsagarakis S, Valassi E, Varlamov EV, Vila G, Wass J, Webb SM, Zatelli MC, Biller BMK
Lancet Diabetes Endocrinol 2021 Dec;9(12):847-875. Epub 2021 Oct 20 doi: 10.1016/S2213-8587(21)00235-7. PMID: 34687601Free PMC Article
Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline.
Melmed S, Casanueva FF, Hoffman AR, Kleinberg DL, Montori VM, Schlechte JA, Wass JA; Endocrine Society
J Clin Endocrinol Metab 2011 Feb;96(2):273-88. doi: 10.1210/jc.2010-1692. PMID: 21296991

Recent clinical studies

Etiology

A comprehensive review of the role of long non-coding RNAs in organs with an endocrine function.
Ghafouri-Fard S, Esmaeili M, Shoorei H, Taheri M
Biomed Pharmacother 2020 May;125:110027. Epub 2020 Feb 25 doi: 10.1016/j.biopha.2020.110027. PMID: 32106365
MicroRNA‑16/VEGFR2/p38/NF‑κB signaling pathway regulates cell growth of human pituitary neoplasms.
Lu B, Liu GL, Yu F, Li WJ, Xiang XX, Xiao HZ
Oncol Rep 2018 Mar;39(3):1235-1244. Epub 2018 Jan 22 doi: 10.3892/or.2018.6227. PMID: 29399695
Disruption of aromatase homeostasis as the cause of a multiplicity of ailments: A comprehensive review.
Patel S
J Steroid Biochem Mol Biol 2017 Apr;168:19-25. Epub 2017 Jan 18 doi: 10.1016/j.jsbmb.2017.01.009. PMID: 28109841
Cancer risk among users of oral contraceptives: cohort data from the Royal College of General Practitioner's oral contraception study.
Hannaford PC, Selvaraj S, Elliott AM, Angus V, Iversen L, Lee AJ
BMJ 2007 Sep 29;335(7621):651. Epub 2007 Sep 11 doi: 10.1136/bmj.39289.649410.55. PMID: 17855280Free PMC Article

Diagnosis

Brain Tumor Detection and Classification Using Cycle Generative Adversarial Networks.
Gupta RK, Bharti S, Kunhare N, Sahu Y, Pathik N
Interdiscip Sci 2022 Jun;14(2):485-502. Epub 2022 Feb 9 doi: 10.1007/s12539-022-00502-6. PMID: 35137330
Pituitary surgery's epidemiology using a national inpatient database in Japan.
Hattori Y, Tahara S, Aso S, Matsui H, Fushimi K, Yasunaga H, Morita A
Acta Neurochir (Wien) 2020 Jun;162(6):1317-1323. Epub 2020 Mar 3 doi: 10.1007/s00701-020-04270-4. PMID: 32125502
A comprehensive review of the role of long non-coding RNAs in organs with an endocrine function.
Ghafouri-Fard S, Esmaeili M, Shoorei H, Taheri M
Biomed Pharmacother 2020 May;125:110027. Epub 2020 Feb 25 doi: 10.1016/j.biopha.2020.110027. PMID: 32106365
Downregulation of glucose‑6‑phosphate dehydrogenase by microRNA‑1 inhibits the growth of pituitary tumor cells.
He C, Yang J, Ding J, Li S, Wu H, Xiong Y, Zhou F, Jiang Y, Teng L, Yang J
Oncol Rep 2018 Dec;40(6):3533-3542. Epub 2018 Oct 1 doi: 10.3892/or.2018.6755. PMID: 30272333
ACTH-producing pituitary cancer: experience at the King Faisal Specialist Hospital & Research Centre.
Ahmed M, Kanaan I, Alarifi A, Ba-Essa E, Saleem M, Tulbah A, McArthur P, Hessler R
Pituitary 2000 Oct;3(2):105-12. doi: 10.1023/a:1009957824871. PMID: 11141693

Therapy

Brain Tumor Detection and Classification Using Cycle Generative Adversarial Networks.
Gupta RK, Bharti S, Kunhare N, Sahu Y, Pathik N
Interdiscip Sci 2022 Jun;14(2):485-502. Epub 2022 Feb 9 doi: 10.1007/s12539-022-00502-6. PMID: 35137330
Role of metformin and other metabolic drugs in the prevention and therapy of endocrine-related cancers.
León-González AJ, Jiménez-Vacas JM, Fuentes-Fayos AC, Sarmento-Cabral A, Herrera-Martínez AD, Gahete MD, Luque RM
Curr Opin Pharmacol 2021 Oct;60:17-26. Epub 2021 Jul 23 doi: 10.1016/j.coph.2021.06.002. PMID: 34311387
Pituitary surgery's epidemiology using a national inpatient database in Japan.
Hattori Y, Tahara S, Aso S, Matsui H, Fushimi K, Yasunaga H, Morita A
Acta Neurochir (Wien) 2020 Jun;162(6):1317-1323. Epub 2020 Mar 3 doi: 10.1007/s00701-020-04270-4. PMID: 32125502
Cancer risk among users of oral contraceptives: cohort data from the Royal College of General Practitioner's oral contraception study.
Hannaford PC, Selvaraj S, Elliott AM, Angus V, Iversen L, Lee AJ
BMJ 2007 Sep 29;335(7621):651. Epub 2007 Sep 11 doi: 10.1136/bmj.39289.649410.55. PMID: 17855280Free PMC Article
Gonadotropin-releasing hormone antagonists.
Herbst KL
Curr Opin Pharmacol 2003 Dec;3(6):660-6. doi: 10.1016/j.coph.2003.06.009. PMID: 14644020

Prognosis

A comprehensive review of the role of long non-coding RNAs in organs with an endocrine function.
Ghafouri-Fard S, Esmaeili M, Shoorei H, Taheri M
Biomed Pharmacother 2020 May;125:110027. Epub 2020 Feb 25 doi: 10.1016/j.biopha.2020.110027. PMID: 32106365
Downregulation of glucose‑6‑phosphate dehydrogenase by microRNA‑1 inhibits the growth of pituitary tumor cells.
He C, Yang J, Ding J, Li S, Wu H, Xiong Y, Zhou F, Jiang Y, Teng L, Yang J
Oncol Rep 2018 Dec;40(6):3533-3542. Epub 2018 Oct 1 doi: 10.3892/or.2018.6755. PMID: 30272333
A pituitary carcinoma secreting TSH and prolactin: a non-secreting adenoma gone awry.
Brown RL, Muzzafar T, Wollman R, Weiss RE
Eur J Endocrinol 2006 May;154(5):639-43. doi: 10.1530/eje.1.02141. PMID: 16645009
ACTH-producing pituitary cancer: experience at the King Faisal Specialist Hospital & Research Centre.
Ahmed M, Kanaan I, Alarifi A, Ba-Essa E, Saleem M, Tulbah A, McArthur P, Hessler R
Pituitary 2000 Oct;3(2):105-12. doi: 10.1023/a:1009957824871. PMID: 11141693

Clinical prediction guides

Nose-to-brain delivery of octreotide acetate in situ gel for pituitary adenoma: Pharmacological and in vitro cytotoxicity studies.
Gadhave D, Khot S, Tupe S, Shinde M, Tagalpallewar A, Gorain B, Kokare C
Int J Pharm 2022 Dec 15;629:122372. Epub 2022 Nov 12 doi: 10.1016/j.ijpharm.2022.122372. PMID: 36351503
MicroRNA‑16/VEGFR2/p38/NF‑κB signaling pathway regulates cell growth of human pituitary neoplasms.
Lu B, Liu GL, Yu F, Li WJ, Xiang XX, Xiao HZ
Oncol Rep 2018 Mar;39(3):1235-1244. Epub 2018 Jan 22 doi: 10.3892/or.2018.6227. PMID: 29399695
Cancer risk among users of oral contraceptives: cohort data from the Royal College of General Practitioner's oral contraception study.
Hannaford PC, Selvaraj S, Elliott AM, Angus V, Iversen L, Lee AJ
BMJ 2007 Sep 29;335(7621):651. Epub 2007 Sep 11 doi: 10.1136/bmj.39289.649410.55. PMID: 17855280Free PMC Article

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